Clinical trials: Geriatric Disorders
Female Hypogonadism
Perception of Hormonal Replacement Therapy Among Patients Aged 11 to 17 Years
To establish a current knowledge and perception of patients and their parents regarding HRT in order to assess the needs that can promote understanding and adherence to treatment by implementing therapeutic education workshops
- Trial name
- THS (NCT07315932)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Strasbourg, France
GERIATRIC SYNDROMES, Hip Fractures
Incidence of Geriatric Syndromes Overlap
The overlap of depression and delirium as geriatric syndromes present in elderly patients with hospital admission due to hip fracture has been previously studied.
- Conditions
- GERIATRIC SYNDROMES, Hip Fractures, GERIATRIC ASSESSMENT, Delirium
- Trial name
- NCT03647436
- Testing
- Comprehensive Geriatric Assessment. Both groups.
- Where
- Spain
- Volunteers
- 506 people
- Sponsor
- Hospital de la Ribera
Hip Fracture, Arthrosis
Preventing Loss of Weight, Fat Free Mass and Activities of Daily Living
Malnutrition of elder orthopaedic patients leads to weight loss and loss of fat free mass. Changes in the individual's nutritional status and body composition may adversely affect the patient's postoperative level of activity.
- Trial name
- NCT00373971
- Testing
- Involving the patients in their own nutritional care
- Where
- Denmark
- Volunteers
- 252 people
- Sponsor
- University of Aarhus
Old Age; Debility, Peripheral Neuropathy
Protective Arm Balance Responses
The overall objective of this study is to investigate the effect of attention control training on reach-grasp stabilizing responses during fall-induced perturbations.
- Trial name
- PAT (NCT06388434)
- Testing
- Protective Arm Balance Response Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Leukemia
AT9283 in Treating Young Patients With Relapsed or Refractory Acute Leukemia
RATIONALE: AT9283 may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase I/IIa clinical trial is studying the side effects and best dose of AT9283 in treating young…
- Trial name
- NCT01431664
- Testing
- multikinase inhibitor AT9283, laboratory biomarker analysis, pharmacological study
- Where
- 5 sites in United Kingdom
- Volunteers
- 7 people
- Sponsor
- Cancer Research UK
Myopia, Refractive Errors
Prevalence and Environmental Factors for Myopia Among Chinese School-aged Children and Adolescent in Tianjin
The high prevalence of myopia has become a global public health problem. The study amied to investigate the prevalence and progression of myopia associated with social environmental factors in Tianjin, a Chinese megacity in north…
- Trial name
- NCT05336799
- Where
- China
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
NASH With Fibrosis, NAFLD
AGED Diagnostics Liver Disease Assessment
Continue development of previously established methods to further validate candidate biomarkers that can discriminate steatosis from NASH and separately stage fibrosis from blood.
- Conditions
- NASH With Fibrosis, NAFLD, Healthy
- Trial name
- AGEDDX (NCT06348563)
- Testing
- AGED Multiple Target Assay in Healthy Controls, AGED Multiple Target Assay in NAFLD Participants, AGED Multiple Target Assay in Fibrosis Participants
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Active Genomes Expressed Diagnostics, Corp
Diabetes Mellitus
DiaFrail: A Short Duration Study in Older People ( DIAFRAIL Study)
1. Many patients with type 2 diabetes are not at glycaemic goal and require additional therapy in order to reduce vascular risk and improve symptom control 2.
- Trial name
- DiaFrail (NCT02484209)
- Testing
- Metformin, Glimepiride
- Sponsor
- Diabetes Frail Ltd
Incarcerated Groin Hernia
Suture Repair vs Mesh Repair in the Treatment of Incarcerated Groin Hernia in Elderly Populations
Purpose: Tension-free hernia repair is the gold standard for groin hernia repair. However, there is no consensus on the optimal surgical treatment for incarcerated groin hernia in elderly populations, The aim of this study was to…
- Trial name
- NCT05966285
- Testing
- suture repair, mesh repair
- Volunteers
- 70 people
- Sponsor
- Fudan University
Influenza, Healthy
A Study to Assess the Safety and Immunogenicity of M-001 Influenza Vaccine as a Primer to TIV in Elderly Volunteers
"Multimeric-001" (M-001) has been recently developed, containing conserved, common linear influenza epitopes that activate both cellular and humoral arms of the immune system against a wide variety of influenza A and B strains.
- Trial name
- NCT01419925
- Testing
- Two Multimeric-001 administrations followed by TIV, One administration of Multimeric-001 followed by TIV, One administration of adjuvanted M-001 followed by TIV
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- BiondVax Pharmaceuticals ltd.
Cardiovascular Diseases Risk, Adiposity
Dose-effect of HIIT on Cardiovascular Health of Children
An adequate physical activity level has important effects on cardiovascular health of children. However, the scientific literature suggests that few children meet the physical activity recommendations to obtain these…
- Trial name
- NCT03479658
- Testing
- High intensity interval training, Nutritional education
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Acute Myeloid Leukemia
Safety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood
Quizartinib is an experimental drug. It is not approved for regular use. It can only be used in medical research. Children or young adults with a certain kind of blood cancer (FLT3-ITD AML) might be able to join this study if it…
- Trial name
- NCT03793478
- Testing
- Quizartinib, Fludarabine, Cytarabine
- Where
- 27 sites in United States, Belgium and 8 more
- Volunteers
- 65 people
- Sponsor
- Daiichi Sankyo
Osteoarthritis, Knee
Effects of MatPilates in Pain and Functionality in Elderly Woman With Osteoarthritis.
Introduction: The osteoarthrosis is incurable, one of the most incapacitating disease around the world and your prevalence is increasing every year.
- Trial name
- NCT03321084
- Testing
- MatPliates, Control
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Maria das Graças Rodrigues de Araújo
Malnutrition
Assessment of the Nutritional Status of Children and Adolescents With Malignancies
The main objective of this study was the assessment of the nutritional status of children and adolescents aged between 0-18 with malignancies based on BMI percentiles and standard deviation scores, at diagnosis, during treatment…
- Trial name
- NCT02246452
- Volunteers
- 135 people
- Sponsor
- University of Hohenheim
Prostate Cancer
Assessment of Primary Androgen Deprivation Therapy for Non-metastatic Prostate Cancer Among Elderly
The widespread availability of screening coupled with high risks of over diagnosis, over treatment, and a rising risk of dying from competing causes of deaths pose a major challenge for prostate cancer patients and our health…
- Trial name
- NCT00161252
- Where
- United States
- Sponsor
- University of Medicine and Dentistry of New Jersey
Influenza
Immunogenicity and Safety of Three Dose Levels of OVX836 Candidate Vaccine Against Influenza in Healthy Volunteers.
This Phase 2a clinical trial is designed to evaluate the immunogenicity and the safety of one administration of OVX836 influenza vaccine at different dose levels (180µg, 300μg and 480μg) in order to assess the dose response of…
- Trial name
- NCT05060887
- Testing
- OVX836-003, Saline solution
- Where
- Belgium
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Osivax
Breast Cancer, Lung Cancer
Impact of Geriatrician Interventions on Chemotherapy Delivery in Vulnerable Elderly Oncology Patients
This is a randomized parallel group trial designed to evaluate the impact of implementing geriatrician-prescribed interventions based on the comprehensive geriatric assessment (CGA), on the ability to deliver adequate…
- Conditions
- Breast Cancer, Lung Cancer, Ovarian Cancer, Prostate Cancer
- Trial name
- GIVE (NCT02785887)
- Testing
- Geriatrician review
- Where
- 3 sites in Italy
- Volunteers
- 233 people
- Sponsor
- Azienda USL 4 Prato
Poliomyelitis
A Post-marketing Safety Study of GSK Bio IPV Vaccine (PoliorixTM) in Korean Children
Following licensing of PoliorixTM in Korea, this study will collect safety data about the routine use of this vaccine in 600 children according to the regulations of Korean Food and Drugs Administration (KFDA).
- Trial name
- NCT00514033
- Testing
- Poliomyelitis vaccine (inactivated) -PoliorixTM
- Where
- South Korea
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sarcopenia in Elderly
THE EFFECT OF PROPRIOCEPTIVE EXERCISE TRAINING ON CERVICAL PROPRIOCEPTION, KINESIOPHOBIA, AND PAIN CATASTROPHIZING LEVELS IN SARCOPENIC GERIATRIC INDIVIDUALS RESIDING IN NURSING HOMES
This study investigated the effects of cervical proprioceptive exercise training on cervical proprioception, kinesiophobia and pain catastrophising in sarcopenic nursing home residents.
- Trial name
- NCT07253714
- Testing
- Classic exercises, Proprioceptive exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Atılım University
Cognitive Impairment, Alzheimer Disease
A Multi-domain Lifestyle Intervention Among Aged Community-residents in Zhejiang, China
A study conducted in Finland discovered that a multidomain intervention, consisting of physical activity, nutritional guidance, cognitive training, social activities, and management of vascular risk factors, effectively…
- Conditions
- Cognitive Impairment, Alzheimer Disease, Vascular Cognitive Impairment, Dement
- Trial name
- HERITAGE (NCT05886114)
- Testing
- Structured Multi-domain Intervention, Self-Guided Intervention
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
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