Clinical trials: Geriatric Individuals
Immune Deficiency
Immune Benefits of Consumption of Dairy Yogurt in Elderly
To investigate the impact of consuming dairy yogurt on immun function including natural killer (NK) cell activity, circulating levels of cytokines, and immunoglobulin (Ig) in elderly.
- Trial name
- NCT03051425
- Testing
- Probiotic yogurt
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Skin Quality Improvement, Photo-aged Skin
Fractional CO2 Laser-assisted Delivery of Hyaluronic Acid, Ascorbic Acid and Sodium DNA For Enhancing Facial Skin Quality in Individuals Over the Age of 30
Evaluate the effectiveness of topical hyaluronic acid, ascorbic acid, and sodium DNA following ablative fractional laser treatment in objectively reversing facial skin alterations induced by photoaging.
- Conditions
- Skin Quality Improvement, Photo-aged Skin, Drug Delivery Systems
- Trial name
- FCLADHAAASDFSQ (NCT07376148)
- Testing
- topical hyaluronic acid, ascorbic acid, and sodium DNA following ablative fractional laser treatment
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Diphtheria, Tetanus and Acellular Pertussis, Epidemic Meningitis
Clinical Trial of the Adsorbed Acellular Pertussis (Tricomponent) DTaP-Haemophilus Influenzae Type b (Conjugate)-ACYW135 Group Meningococcal (Conjugate) Combined Vaccine
This clinical trial is conducted in two parts. Part One employs a randomized, partially blinded, dose-escalation, partially active-controlled design. Part Two utilizes a randomized, blinded, placebo-controlled design.
- Conditions
- Diphtheria, Tetanus and Acellular Pertussis, Epidemic Meningitis, Haemophilus Influenzae Type B Infection
- Trial name
- NCT07203755
- Testing
- Adsorbed Acellular Pertussis (3-Component) Diphtheria-Tetanus-Pertussis-Haemophilus influenzae type b (Conjugate)-Meningococcal Group ACYW135 (Conjugate) Combined Vaccine (DTcP-Hib-MCV4), DTcP-Hib-MCV4, Adsorbed Acellular Pertussis (3-Component) Diphtheria-Tetanus-Pertussis (DTcP)
- Where
- China
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Influenza
Phase Ⅱ Clinical Trial of Influenza Virus Split Vaccine for Individuals Aged 60 Years and Above
To evaluate the immunogenicity of administering one dose of influenza virus split vaccine (0.7mL/dose) to individuals aged 60 and above.
- Trial name
- NCT07327398
- Testing
- Influenza virus split vaccine (0.7mL/vial), Influenza virus split vaccine
- Where
- 2 sites in China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Shanghai Institute Of Biological Products
Elderly People
Improving the Quality of Life of Elderly Individuals Living in Nursing Homes
The development of physical activity (PA) and exercise habits improves strength, flexibility, balance and coordination, activities such as walking, sleep quality and cognitive status in elderly people and supports their…
- Trial name
- NCT06520956
- Testing
- Video based exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Galata University
Streptococcus Pneumoniae Pneumonia
Phase Ⅱ Clinical Trial of 24-valent Pneumococcal Polysaccharide Conjugate Vaccine
In the treatment of pneumococcal diseases, the common use of penicillin-based antimicrobial agents has led to drug resistance, which has become a global challenge. Therefore, disease prevention through vaccination is essential.
- Trial name
- NCT07035054
- Testing
- low dose-1, low dose-2, high dose
- Where
- China
- Volunteers
- 992 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
Frail Elderly
Comparison of the Effects of Different Exercise Protocols in Frail Elderly Individuals
The aim of this research is to investigate and compare the effects of two different exercise programs developed for frail geriatric individuals on fall risk, fear of falling, and physical performance.
- Trial name
- NCT07564076
- Testing
- Vivifrail Exercise Program, Otago Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Healthy, Mild Cognitive Impairment
tES Effects on Associative Memory Performance
Previous studies showed that transcranial electric stimulation (tES) applied over the prefrontal cortex improves cognitive performance in healthy elderly adults as well as in patients suffering from mild cognitive impairment or…
- Conditions
- Healthy, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT03351452
- Testing
- real anodal transcranial direct current stimulation, real transcranial alternating current stimulation
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Bern
Influenza Immunization, Health Volunteers
A Study to Assess Tolerability of the Trivalent Recombinant Vaccine in Individuals Aged 18 and Older Using the Vaccinees Perception of Injection Questionnaire
This study aims to assess patient-reported experiences following trivalent recombinant influenza vaccine (RIV3) vaccination using the Vaccinees' Perception of Injection (VAPI) questionnaire, identify factors related to vaccine…
- Trial name
- NCT06765187
- Testing
- Trivalent Recombinant Influenza Vaccine
- Where
- United States
- Volunteers
- 1,007 people, healthy volunteers welcome
- Sponsor
- Sanofi
Aging, Age-Related Cognitive Decline
Multidomain Interventions for Elderly Individuals in Residential Structures
The "Multidomain Interventions to improve the COgnitive and fUNctional well-being of elderly individuals in residential sTructures" (I-COUNT) study aims to test the feasibility and the effectiveness of a multidisciplinary…
- Conditions
- Aging, Age-Related Cognitive Decline, Sarcopenia, Long Term Care Facility
- Trial name
- I-COUNT (NCT06820710)
- Testing
- Physical activity, Cognitive stimulation, Nutritional Intervention
- Where
- 2 sites in Italy
- Volunteers
- 90 people
- Sponsor
- Istituto di Neuroscienze Consiglio Nazionale delle Ricerche
Sedentary Behavior
Effect of Cocoa Supplementation and Aerobic Exercise on Pressure Parameters
This study evaluates the cocoa supplementation and aerobic exercise on central pressure and arterial stiffness parameters in physically inactive middle-aged individuals. 500mg capsules will be offered to all patients.
- Trial name
- NCT04732754
- Testing
- Aerobic exercise + Theobroma cocoa (AETC), Control Group (CG), Aerobic Exercise (AE)
- Where
- Brazil
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
SARS-CoV-2
Safety and Immunogenicity of GX-19N, a COVID-19 Preventive DNA Vaccine in Elderly Individuals
The objective of the study is to demonstrate safety and immunogenicity of COVID-19 preventive DNA vaccine in elderly individuals.
- Trial name
- NCT04915989
- Testing
- GX-19N
- Where
- 2 sites in South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Genexine, Inc.
Home Care for Elderly or Disabled Individuals
Evaluating the Impact of Training for IHSS Workers
This trial investigates whether high-quality training for consumer-directed home health workers impacts health outcomes for care consumers and employment outcomes for care workers.
- Trial name
- NCT06205433
- Testing
- IHSS Basic Training
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Abdul Latif Jameel Poverty Action Lab
Muscle Function, Mitochondrial Function, Overweight
AMAZ-02 Effect on Exercise ToLerance in Healthy, Overweight Middle Aged Subjects (ATLAS Trial)
This is a Phase 2 randomized, double-blind, placebo-controlled study enrolling 90 healthy, overweight, middle aged subjects (30 placebo, 30 low dose and 30 high dose AMAZ-02 intervention), 40-65 years of age, who are otherwise…
- Conditions
- Muscle Function, Mitochondrial Function, Overweight, Healthy Aging
- Trial name
- ATLAS (NCT03464500)
- Testing
- Mitopure 500mg, Mitopure 1000mg
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Elderly Immune Senescence
Pilot Study to Evaluate Immunopotentiating Effects of Immulina in Elderly Individuals
This will be a small study aimed at determining the effects of oral Immulina consumption on the immune system in elderly individuals.
- Trial name
- NCT01784692
- Testing
- Immulina
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Immune Senescence
Influence of Persistent CMV-infection on Immune Senescence
Recent studies indicate that persistent viral infections particularly with Cytomegalovirus (CMV) might have a negative impact on immune senescence (i.e. immunocompetence of elderly individuals).
- Trial name
- NCT00461695
- Testing
- Vaccination against TBEV (FSME Immun CC)
- Where
- Switzerland
- Volunteers
- 183 people
- Sponsor
- University of Zurich
Geriatric Individuals, Cognitive Function
Attentional Focus Training in Older Adults
The ability to walk safely and efficiently is crucial for older adults to maintain their independence and minimize the risk of falls.
- Conditions
- Geriatric Individuals, Cognitive Function, Physical Performance
- Trial name
- NCT06700928
- Testing
- External focus training, Internal focus training, No attentional focus training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Müşerref Ebru YALÇIN
Subclinical Hypothyroidism
Mechanistic Study of Subclinical Hypothyroidism In the Elderly
Subclinical hypothyroidism, defined as an elevated TSH in the setting of normal thyroid hormone levels, is a common diagnosis in the elderly.
- Trial name
- NCT02399475
- Testing
- Levothyroxine, Liothyronine, Thyrotropin-Releasing Hormone
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Pennsylvania
Mild Cognitive Impairment
Real-time fMRI Neurofeedback in Patients With MCI
Increased activity in the hippocampus (i.e., hyperactivity) during a fMRI memory task was found in patients with Mild Cognitive Impairment due to Alzheimer's disease (MCI).
- Trial name
- NCT04020744
- Testing
- real-time fMRI based neurofeedback from the hippocampus, real-time fMRI based neurofeedback from another brain area
- Where
- 2 sites in Switzerland
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Bern
Frail Elderly
Pilot Study of Virtual Gait Training in Older Adults
Older individuals suffer from falls and fear of falling. The purpose of this study was to determine the effectiveness of a novel virtual gait training on walking performance and fear of falling in older adults, and to evaluate…
- Trial name
- NCT01607736
- Testing
- Virtual Gait Training
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland