Clinical trials: Gestational Age
Premature Infants
Urine Concentration of S100B in Extremely Premature Infants
S100B, a calcium-binding protein, is found predominantly in the central nervous system (CNS) and is increased in CSF and blood after CNS injury. There are two objectives to this study.
- Trial name
- NCT00747591
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Utah
Premature, Nutrition Disorders
Comparison of the Effects of Oral Stimulation and Non-nutritive Sucking Practices
This study, it was aimed to compare the effects of oral stimulation and non-nutritive sucking practices on the transition to full oral feeding in babies with a gestational age of 26-32 weeks.
- Conditions
- Premature, Nutrition Disorders, Sucking Behavior
- Trial name
- NCT05249179
- Testing
- Pacifier, Oral stimulation
- Volunteers
- 140 people
- Sponsor
- Ankara City Hospital Bilkent
Foetal Growth Problem, Small for Gestational Age
Growth Hormone Treatment of Children Born With Retarded Intrauterine Growth at Age 2-5 Years
This trial is conducted in Europe. The aim of this trial is to evaluate the efficacy and tolerance of a new growth hormone (GH) formulation, in the treatment of children born with retarded intrauterine growth, starting at age 2…
- Trial name
- NCT00184691
- Testing
- somatropin
- Where
- 13 sites in Spain
- Volunteers
- 78 people
- Sponsor
- Novo Nordisk A/S
Preterm Labor
Oral Nifedipine vs Vaginal Progesterone for Prolonging Pregnancy in Preterm Labor
The purpose of this randomized clinical trial is to compare oral nifedipine and vaginal progesterone for prolonging pregnancy in women who develop preterm labor.
- Trial name
- NCT07865949
- Testing
- Nifedipine 20 Mg, Vaginal micronized progesterone
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Medicare Hospital (Pvt) Limited
Small for Gestational Age
A Phase III Clinical Study of Jinpei Growth Hormone Injection in the Treatment of Short Stature Children With Small for Gestational Age (SGA)
This is a multicenter, randomized, open-label, active-controlled Phase III clinical study to evaluate the efficacy, safety and pharmacokinetic (PK) characteristics of once-weekly PEG-hGH injection compared with once-daily hGH…
- Trial name
- NCT07841678
- Testing
- PEG-hGH Injection, hGH Injection
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Foetal Growth Problem, Small for Gestational Age
Long Term Effect of Somatropin in Subjects With Intrauterine Growth Retardation
This trial is conducted in Europe. The aim of this trial is to assess the safety of long-term growth hormone treatment in growth-retarded children with intrauterine growth retardation (IUGR) enrolled in trial GHRETARD/F/1/F.
- Trial name
- NCT01734447
- Testing
- somatropin
- Where
- France
- Volunteers
- 57 people
- Sponsor
- Novo Nordisk A/S
Cardiovascular Diseases, Diabetes
Fit After Baby: Increasing Postpartum Weight Loss in Women at Increased Risk for Cardiometabolic Disease
This study plans to learn more about how to increase postpartum weight loss and how to decrease risk factors for postpartum women at increased risk for diabetes and heart disease.
- Conditions
- Cardiovascular Diseases, Diabetes, Gestational Diabetes, Preeclampsia
- Trial name
- FAB (NCT03215173)
- Testing
- Fit After Baby, Text4Baby Control Group
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Growth Hormone Deficiency, Idiopathic Short Stature
Constructing an Insulin-Like Growth Factor-based Prediction Model
Serum insulin-like growth factor-I (IGF-I) measurements have been shown to correlate well with growth hormone action and effect, and recent data show that serum IGF-I may be related to safety and efficacy of growth hormone (GH)…
- Conditions
- Growth Hormone Deficiency, Idiopathic Short Stature, Small for Gestational Age
- Trial name
- NCT00263445
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Los Angeles
Extubation Failure, Prematurity
Comparing HHHFNC and nCPAP Ventilation Methods for the Prevention of Extubation Failure in Preterm Infants
Purpose is to show that HHHFNC method is as effective and safe as nCPAPand even more comfortable than it as non-invasive respiratory support for the prevention of extubation failure in preterm with gestational age of 26-32 weeks.
- Trial name
- NCT02887846
- Testing
- Heated Humidified High-Flow Nasal Cannula
- Volunteers
- 200 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Hypothermia
Warming Mattress Versus Polyethylene Wrapping to Prevent Hypothermia in Preterm Newborns.
Mean axillary temperatures, taken during NICU resuscitation upon admission to the NICU, will not differ between VLBW babies who are occlusively wrapped and very low birth weight (VLBW) babies who are placed on thermal warming…
- Trial name
- NCT00603837
- Testing
- NeoWrap, InfaTherm
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Small for Gestational Age Infants, Appropriate for Gestational Age Infants
The Correlation Between the n-6:n-3 Ratio and Inflammatory Markers in Small for Gestational Age (SGA) Infants Compared With Appropriate for Gestational Age (AGA) Infants
Numerous studies have recommended the use of n-3 PUFA supplementation during human pregnancy and lactation for the prevention of preterm birth, beneficial effects on fetal development, visual and cognitive development and other…
- Trial name
- NCT02887664
- Testing
- Blood test
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Complication Due to Immunization
Cardio-respiratory Events and Inflammatory Response After Primary Immunization in Preterm Infants
Background: Inflammation may depress respiration in neonates. The aim of this study was to establish a link between post-immunization inflammation and cardio-respiratory events (CRE).
- Trial name
- NCT02726178
- Testing
- Advil® Pediatric drops for infants
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Materno-fetal Transfer of Anti-HCMV-IgG, Materno-fetal Transfer of Anti-VZV-IgG
Diaplacental Transfer of Anti-HCMV- and Anti-VZV-immunoglobulin G (IgG) -Antibodies at Premature and Mature Newborns
The aim of the study is to determine the total concentration of HCMV- and VZV-specific IgG-antibodies and the total concentration of neutralizing antibodies against HCMV in neonatal bloodstream depending on gestational age at…
- Trial name
- MoChi-HCMV (NCT02689700)
- Testing
- Blood samples
- Where
- Germany
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Thrombocytopenia, Neonatal
Neonatal Platelet Transfusion Threshold Trial
The objective of the NeoPlaTT trial is to test whether, among extremely preterm infants born at 23 0/7 to 26 6/7 weeks' gestation, a lower platelet transfusion threshold, compared to a higher threshold, improves survival without…
- Conditions
- Thrombocytopenia, Neonatal, Platelet Transfusion, Infant, Newborn, Diseases
- Trial name
- NeoPlaTT (NCT06676904)
- Testing
- Higher Platelet Transfusion Threshold, Lower Platelet Transfusion Threshold
- Where
- 20 sites in United States
- Volunteers
- 2,433 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Infant, Newborn, Infant, Low Birth Weight
Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity
The purpose of this trial was to determine the efficacy and safety of supplemental therapeutic oxygen for infants with prethreshold retinopathy of prematurity (ROP) to reduce the probability of progression to threshold ROP and…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- STOP-ROP (NCT01203436)
- Testing
- Supplemental Oxygen Management, Conventional Oxygen Management
- Where
- 9 sites in United States
- Volunteers
- 649 people
- Sponsor
- NICHD Neonatal Research Network
The Primary Outcome is Preterm Delivery Before 28 Weeks Gestational Age Compared to Women With One vs Two Cerclages Placed
Single Versus Double Suture Cervical Cerclage to Prevent Preterm Birth
Cerclage placement is known to be beneficial in prevention of preterm birth when placed inn a certain subset of patients. Clinically, the number of sutures can also vary by surgeon preference to one or two sutures in one…
- Trial name
- NCT04742647
- Testing
- Double cerclage, Single cerclage
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Contraception, Fetal Growth Retardation
Obesity and Oral Contraceptive Failure
Contraceptive failure is the primary cause of unintended pregnancy in the United States. With obesity rates at epidemic proportions, any association between obesity and strategies that prevent undesired pregnancies constitutes a…
- Conditions
- Contraception, Fetal Growth Retardation, Infant, Small for Gestational Age, Obesity
- Trial name
- NCT01944306
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Labor Long
Effect of Date Fruit Consumption in Later Pregnancy
EFFECT OF DATE FRUIT CONSUMPTION IN LATER PREGNANCY ON LENGTH OF GESTATION LABOR AND DELIVERY OF NULLIPAROUS WOMEN
- Trial name
- NCT05105893
- Testing
- Dates group
- Where
- Pakistan
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Pak Emirates Military Hospital
Childhood Overweight
Effects of Lifestyle Intervention on Childhood Outcomes in LGA Infants
Large-for-gestational-age (LGA) infants have a higher risk of metabolic disease later in life, and their postnatal growth in early childhood may be associated with long-term adverse outcomes.
- Trial name
- NCT04661449
- Testing
- Comprehensive lifestyle intervention
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Gestational Diabetes Mellitus, Type 2 Diabetes Mellitus
Managing Diabetes During Pregnancy in the Wireless Age
This Randomized Controlled Trial (RCT) will test the efficacy of a home blood glucose telemonitoring system against usual care in women with gestational diabetes mellitus (GDM) or type 2 diabetes mellitus (T2DM) during pregnancy.
- Trial name
- NCT01474525
- Testing
- Home Blood Glucose Telemonitoring System
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital