Clinical trials: Gestational Diabetes
Prediabetic State, Obesity
Presessions for the National Diabetes Prevention Program
The National Diabetes Prevention Program (NDPP) is a widely available, evidence-based intervention that promotes weight loss to prevent type 2 diabetes; however, participant attendance is problematic and leads to suboptimal…
- Conditions
- Prediabetic State, Obesity, Gestational Diabetes
- Trial name
- NCT04022499
- Testing
- Presessions, National Diabetes Prevention Program
- Where
- United States
- Volunteers
- 483 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Diabetes During Pregnancy, Gestational Diabetes
Managing Diabetes in Pregnancy Using Cell Phone/Internet Technology
To compare compliance and satisfaction between a traditional method of blood glucose reporting using voicemail (control) and a novel method using cell phone /internet (Confidant) technology in the management of diabetic pregnant…
- Trial name
- NCT01907516
- Testing
- Cell phone-internet home glucose reporting system, Voicemail home blood glucose reporting
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hawaii Pacific Health
Gestational Diabetes
Postpartum Continuous Glucose Monitoring (CGM) Study
This research study is being done to assess if using a glucose sensor (also known as a continuous glucose monitor) after childbirth can help identify women who are at risk of developing diabetes after having diabetes during…
- Trial name
- NCT05714761
- Testing
- Dexcom glucose sensor
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Diabetes, Gestational
Outpatient Cervical Ripening With Orally Administered Misoprostol in Diabetics
A. Null Hypothesis: In term pregnancies complicated by diabetes, there is no difference in the time interval from start of induction to delivery when outpatient cervical ripening and labor induction is initiated with orally…
- Trial name
- NCT00514618
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
Diabetes, Gestational, Gestational Weight Gain
Meals for Moms: Medically-Tailored Meals for Women Who Had Gestational Diabetes
The purpose of this research study is to test whether delivery of medically tailored meals (meals designed specifically to be healthy) can be used to help reduce high blood sugar after delivery of a baby.
- Conditions
- Diabetes, Gestational, Gestational Weight Gain, Postpartum Weight Retention
- Trial name
- NCT04866823
- Testing
- Medically Tailored Meals
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Wake Forest University Health Sciences
Diabetes, Gestational
Correlation of Continuous Glucose Monitoring and Glucose Tolerance Testing With Pregnancy Outcomes
Diabetic pregnant patients are at risk for adverse pregnancy outcomes, including larger than expected fetuses and unplanned operative deliveries, due to elevated blood glucose levels.
- Trial name
- NCT00850135
- Testing
- The Seven Continuous Glucose Monitoring System
- Where
- 2 sites in United States
- Volunteers
- 57 people
- Sponsor
- Stanford University
Gestational Diabetes, Diagnoses Disease
Fasting Versus Fed: Effect of Oral Intake Prior to the Glucose Tolerance Test in Pregnancy
Studies suggest that the timing interval between oral intake and the 1-hour gestational diabetes screen may have a significant impact on gestational diabetes screening glucose levels.
- Conditions
- Gestational Diabetes, Diagnoses Disease, Pregnancy in Diabetic, Glucose, High Blood
- Trial name
- NCT04547023
- Testing
- Fasting before gestational diabetes screen, Per oral intake of food and drink
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Stanford University
Diabetes, Gestational
Metformin Postpartum for GDM RCT for Reduced Weight Retention
The purpose of this study is to determine whether the study drug metformin is helpful in reducing weight after pregnancy in women with gestational diabetes.
- Trial name
- NCT01280409
- Testing
- Metformin
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- The University of Texas Health Science Center, Houston
Infants of Diabetic Mothers
Fatty Acid Ethyl Esters in Meconium of Infants of Diabetic Mothers: a Pilot Trial
Gestational diabetes mellitus (GDM) affects as many as 14% of women in the United States. Furthermore, the number of pregnant women with pregestational diabetes mellitus (PGDM) is also increasing, mainly due to an increase in the…
- Trial name
- FAEE-IDM (NCT02308735)
- Testing
- N/A - No intervention
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Gestational Diabetes, Obesity
Early Gestational Diabetes Screening in the Gravid Obese Woman
Specific Aim 1: To test the hypothesis that early GDM screening between 14-18 weeks in obese women (body mass index ≥30.0) will result in improved perinatal outcomes.
- Trial name
- EGGO (NCT01864564)
- Testing
- Early Screen
- Where
- 2 sites in United States
- Volunteers
- 962 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Gestational Diabetes, Pregnancy
Comparison of Two Screening Strategies for Gestational Diabetes (GDM2)
This is a single site blinded RCT of 920 pregnant women with singleton gestation designed to compare the Carpenter-Coustan and IADPSG criteria for diagnosing gestational diabetes.
- Conditions
- Gestational Diabetes, Pregnancy, Glucose Intolerance
- Trial name
- GDM2 (NCT02309138)
- Testing
- Gestational diabetes screening with fasting 3 hour 100 gm, Gestational diabetes screening with fasting 2 hour 75g
- Where
- United States
- Volunteers
- 921 people, healthy volunteers welcome
- Sponsor
- Esa M Davis, MD MPH FAAFP
Diabetes Prevention in Women After GDM Who Are at High-risk
Dapagliflozin and Metformin,Alone and in Combination, in Overweight/Obese Prior GDM Women
Women with a history of gestational diabetes (GDM) are at substantially increased risk of type 2 diabetes mellitus (T2DM). Compared with the general population, these women are more likely to be overweight or obese.
- Trial name
- DAPA-GDM (NCT02338193)
- Testing
- DAPA/MET XR, DAPA, MET XR
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Woman's
Gestational Diabetes
Continuous Glucose Monitoring for Screening for Diabetes in Pregnancy
The purpose of this study is to evaluate whether Continuous glucose monitoring (CGM) for diagnosis of gestational diabetes mellitus (GDM) improves maternal and neonatal outcomes related to GDM and to evaluate whether CGM for GDM…
- Trial name
- NCT05430204
- Testing
- Group 1: one-hour GCT, Group 2: CGM placement
- Where
- United States
- Volunteers
- 1,628 people
- Sponsor
- The University of Texas Health Science Center, Houston
Gestational Diabetes
Ursodeoxycholic Acid vs Metformin in Gestational Diabetes Mellitus
GUARD is a Clinical Trial that wants to explore the impact of UDCA compared to metformin in the treatment of GDM. The trial wants to recruit 158 women who are overweight or obese who have been diagnosed with GDM, and require…
- Trial name
- GUARD (NCT04407650)
- Testing
- Metformin, Ursodeoxycholic Acid
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- King's College London
Gestational Diabetes
Effect of Fibre Supplements on Gestational Diabetes
The primary aim of this study is to evaluate the effect of a soluble fibre supplement in the development of gestational diabetes in women at high-risk.
- Trial name
- GG-GDM (NCT03547960)
- Testing
- Guar gum, Cellulose
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Gestational Diabetes
RCT Metformin for Reduction of Gestational Diabetes Mellitus Effects
The overall objective of the EMERGE trial is to determine whether metformin + usual care, compared to placebo + usual care (introduced at the time of initial diagnosis of GDM), reduces a) the need for insulin use, or…
- Trial name
- EMERGE (NCT02980276)
- Testing
- Metformin Hydrochloride
- Where
- 2 sites in Ireland
- Volunteers
- 535 people
- Sponsor
- National University of Ireland, Galway, Ireland
Gestational Diabetes
Metformin Compared to Glyburide in Gestational Diabetes
Our hypothesis is that metformin and glyburide will have equal efficacy in controlling blood glucose in gestational diabetics with no increase in adverse maternal, fetal or neonatal outcomes.
- Trial name
- NCT00965991
- Testing
- metformin, Glyburide
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
IUGR, Gestational Diabetes
PED NEONAT 20-000599 Fetal Body Composition
Obesity is an ongoing public health problem that is difficult to treat. There is evidence that obesity has fetal origins. Body composition, including visceral, subcutaneous, brown, and hepatic fat have been found to be important…
- Conditions
- IUGR, Gestational Diabetes, Pregnancy Related
- Trial name
- NCT04508751
- Testing
- 3T "Free-Breathing" Fetal Magnetic Resonance Imaging
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gestational Diabetes, Maternal Complication of Pregnancy
CAPO: Continuous Glucose Monitoring in A2 Gestational Diabetes and Pregnancy Outcomes
This study will utilize continuous glucose monitoring in women with A2 gestational diabetes. Women will be randomized to continuous glucose monitoring or routine care with fingersticks to check their blood glucose four times…
- Trial name
- CAPO (NCT04219085)
- Testing
- Continuous Glucose Monitor, Routine Care
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Yale University
Disorder of Glucose Regulation
Sitagliptin + Metformin Compared to Metformin Monotherapy and Placebo in Women With a Recent GDM
Gestational diabetes mellitus (GDM) is defined as "any degree of glucose intolerance with onset or first recognition during pregnancy." GDM is one of the most frequent metabolic disorders occurring during pregnancy.
- Trial name
- NCT01856907
- Testing
- Sitagliptin-Metformin, Metformin
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Woman's