Clinical trials: Gestational Hypertension
Pre-Eclampsia, Gestational Diabetes
Lifestyle Intervention for Women With Recent Pre-eclampsia or Gestational Diabetes Mellitus ('Mom's Healthy Heart')
The aim of this pilot intervention study is to develop and test a tailored web-based lifestyle modification program for women with recent preeclampsia or gestational diabetes. Women will start the study 3-15 months postpartum.
- Trial name
- NCT03993145
- Testing
- Web-based lifestyle intervention
- Where
- 2 sites in Norway
- Volunteers
- 44 people
- Sponsor
- Norwegian University of Science and Technology
Hypertension in Pregnancy
Mindfulness & Mechanisms Study
Hypertensive disorders of pregnancy (HDP) are the most common medical condition affecting pregnancy and a leading cause of maternal morbidity and mortality in the Unites States.
- Trial name
- NCT04626245
- Testing
- Mindfulness training
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Lifespan
Obstructive Sleep Apnea
Targeted CPAP Therapy for Obstructive Sleep Apnea in Pregnancy
Prospective, randomized controlled trial. Pregnant women in early pregnancy will be randomized to either the Sleep Study + CPAP (Continuous Positive Airway Pressure Therapy) group or to a Standard Prenatal Care group.
- Trial name
- NCT02755831
- Testing
- CPAP, Pre-natal care
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Postpartum Hypertension (PPHT)
Swiss Postpartum Hypertension Cohort
This open label, prospective observational, single-center registry is to study short-, intermediate-and long-term course of postpartum hypertension and predictors/risk factors associated with long term cardiovascular and renal…
- Trial name
- NCT04690660
- Testing
- Data collection for parameters of organ damage (cardiac and renal blood markers), Data collection for blood pressure (BP), Home-based blood pressure management (substudy)
- Where
- Switzerland
- Volunteers
- 480 people
- Sponsor
- University Hospital, Basel, Switzerland
Gestational Hypertension, Hypertension in Pregnancy
A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies (HP)
This trial is a pilot-scale, single institution randomized, placebo-controlled trial to assess the feasibility, acceptability, and efficacy of administering dapagliflozin for cardiovascular risk reduction in the postpartum…
- Conditions
- Gestational Hypertension, Hypertension in Pregnancy, Pre-Eclampsia, Superimposed Pre-Eclampsia
- Trial name
- DAPA-HP (NCT06785116)
- Testing
- Dapagliflozin 10mg Tab
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Michigan
Small for Gestational Age (Disorder), Pre-Eclampsia
Establishing First Trimester Markers for the Identification of High Risk Twin
The purpose of this study is to determine whether we can establish different markers suc as mean arterial pressure , flow in the uterine arteries, biochemical markers in maternal blood and more un the first trimester, in order to…
- Trial name
- NCT02031393
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Assaf-Harofeh Medical Center
Gestational Diabetes Mellitus With Baby Delivered
Carbohydrate Counting and DASH Intervention and Pregnancy Outcomes Among Women With Gestational Diabetes
Study is an interventional clinical trial. Pregnant women (aged 25-40 years) diagnosed with GDM (by a 75-g oral glucose tolerance test at 24-28 weeks' gestation) will be recruited conveniently from Obstetrics and Gynecology…
- Trial name
- NCT03244579
- Testing
- Dietary Intervention
- Where
- Jordan
- Volunteers
- 180 people
- Sponsor
- University of Jordan
Muc3, Pregnancy Induced Hypertension
Investigation of the Serum Mucoprotein 3 (MUC3) Protein Levels in Gestational Hypertensive Disease
Hypertensive diseases of pregnancy are one of the most frequently encountered reasons for maternal and neonatal morbidity and mortality.
- Trial name
- MUC3 (NCT04421183)
- Testing
- draw blood
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Pregnancy Induced Hypertension
Breathing Exercise in Pregnancy-induced Hypertension
To determine the effects of Breathing control vs Alternate nostril breathing on maternal cardiovascular parameters in pregnancy and to determine the effect of breathing control vs Alternate nostril breathing on Fetal Heart rate.
- Trial name
- NCT05828615
- Testing
- Group A, Group B
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Preeclampsia
Clonidine Versus Captopril for Treatment of Postpartum Very High Blood Pressure
The postpartum period represents a stage of the pregnancy-puerperal still rarely addressed scientifically. There are no reports in the literature and concrete enough to elucidate important issues, especially in the field of…
- Trial name
- CLONCAP (NCT01761916)
- Testing
- CLONIDINE, CAPTOPRIL
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Preterm Birth, Low Birth Weight
Perinatal Conditions Influencing Morbidity, Mortality, and Medical Care in Newborns
This study focuses on understanding the conditions that affect newborn health and survival from pregnancy to the first weeks of life at the Isidro Ayora Hospital.
- Conditions
- Preterm Birth, Low Birth Weight, Intrauterine Growth Restriction (IUGR), Perinatal Asphyxia
- Trial name
- UCE (NCT06653374)
- Testing
- Infant, Premature
- Where
- Ecuador
- Volunteers
- 26,000 people
- Sponsor
- HOSPITAL GINECO OBSTETRICO ISIDRO AYORA
Maternal Death, Neonatal Death
Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana
Introduction Maternal and neonatal mortality continue to be to be prominent public health issues in sub Saharan Africa including Ghana, with slow progress made towards attainment of Millennium Development Goals (MDG) 4 \& 5.
- Conditions
- Maternal Death, Neonatal Death, Postpartum Haemorrhage, Pre-eclampsia
- Trial name
- Accelerate (NCT02468310)
- Testing
- Maternal and neonatal emergency protocols
- Where
- Ghana
- Volunteers
- 65,831 people, healthy volunteers welcome
- Sponsor
- Hannah Brown Amoakoh
Preeclampsia, Small for Gestational Age at Delivery
Early Vascular Adjustments to Prevent Preeclampsia
Women destined to develop gestational hypertensive complications often exhibit deviant hemodynamic adaptation patterns before overt clinical disease.
- Conditions
- Preeclampsia, Small for Gestational Age at Delivery, HELLP Syndrome
- Trial name
- NCT04216706
- Testing
- tailored pharmaceutical treatment
- Where
- Netherlands
- Volunteers
- 314 people
- Sponsor
- Maastricht University Medical Center
Pregnancy Related, Hypertension in Pregnancy
Deep Breathing Techniques (Pranayama) in Pregnancy
Slow deep breathing actives the vagal nerve and leads to a natural reduction in physiological parameters such as blood pressure, heart rate and digestion. The effects of these techniques have not been assessed in pregnancy.
- Conditions
- Pregnancy Related, Hypertension in Pregnancy, Blood Pressure
- Trial name
- NCT05341921
- Testing
- Alternate Nostril Breathing, Bhramari Breathing, Sheetali Breathing
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Hypertension in Pregnancy
Perinatal Outcomes in Patients With Elevated sFlt-1/PlGF Ratio
Retrospective cohort study that evaluated 190 subjects admitted with diagnosis of hypertensive disorder of pregnancy, between 24 and 36 6/7 weeks, with an sFlt-1/PlGF index greater than or equal to 110.
- Trial name
- NCT06403722
- Testing
- Standard of care
- Where
- Panama
- Volunteers
- 190 people
- Sponsor
- Saint Thomas Hospital, Panama
Hypertension, Pregnancy
Measuring Blood Pressure in Pregnancy Using Mercury and Automated Device
The aim of the PRAM study was to determine whether women diagnosed with hypertension in pregnancy, using the traditional mercury device, have the same pregnancy outcomes when blood pressure is measured by either an automated…
- Conditions
- Hypertension, Pregnancy, Pre Eclampsia
- Trial name
- PRAM (NCT00809666)
- Testing
- Automated blood pressure recording device Omron HEM 705CP
- Where
- Australia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- St George Hospital, Australia
Pregnancy Induced Hypertension
Optical Coherence Tomography Angiography Compared to Maternal Doppler in Screening for Hypertension in Pregnancy
Pregnancy related hypertension is one of the most prevalent obstetric complications. The aim of the study is to evaluate the validity and sensitivity of OCT angiography in prediction of pregnancy induced hypertensive disorders in…
- Trial name
- NCT05330949
- Testing
- Optical coherence Tomography Angiography, Uterine artry doppler
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Pregnant Women With Singleton Pregnancies
Harvesting Health: Advancing Nutrition and Wellness for Moms and Babies
This is a randomized controlled trial to assess whether a personalized food kit to pregnant women is feasible, improves diet quality, and enhances pregnancy and birth outcomes compared to standard prenatal care.
- Trial name
- HH (NCT07659821)
- Testing
- Food Kit
- Where
- 3 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Pregnancy, Eclampsia
A Cluster-Randomized Trial of Ultrasound Use to Improve Pregnancy Outcomes in Low Income Country Settings
In many low-income countries, the use of ultrasound by medical officers and non-physician health care staff (e.g., midwives) for antenatal identification of high risk pregnancies is a new intervention requiring authoritative…
- Conditions
- Pregnancy, Eclampsia, Placenta Previa, Stillbirth
- Trial name
- NCT01990625
- Testing
- Antenatal Ultrasound Scan
- Where
- 5 sites in Guatemala, Kenya and 3 more
- Volunteers
- 45,038 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Periodontal Diseases, Pregnancy Complications
Oral Health and Adverse Pregnancy Complications
Pregnant women are susceptible to develop periodontitis, but these oral health changes related to pregnancy are often neglected.
- Conditions
- Periodontal Diseases, Pregnancy Complications, Pregnancy Preterm, Gestational Diabetes
- Trial name
- NCT06110143
- Testing
- Periodontal treatment
- Where
- 3 sites in Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg