Clinical trials: Ghrelin
Diabetes Mellitus, Type 2, Obesity
Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Obesity and Insulin Resistance
Being overweight or obese has been associated with insulin resistance contributing to an increased risk for the development of type II diabetes.
- Trial name
- NCT04926415
- Testing
- taVNS
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Burrell College of Health Sciences
Healthy
Study of Glucagon, Ghrelin and Growth Hormone as Counterregulatory Hormones
Glucagon has been used for decades as a test of growth hormone (GH) reserve. The pathway by which GH is stimulated by glucagon is not established.
- Trial name
- NCT01795235
- Testing
- Saline, Glucagon, Atenolol
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Dementia
Circulating Ghrelin as a Biomarker for Dementia
The primary objective of this study will explore whether circulating acyl-ghrelin (AG) and unacylated-ghrelin (UAG) are reduced in neurodegenerative disease associated with cognitive impairment.
- Trial name
- GDEM3 (NCT05381090)
- Testing
- Venous blood collection
- Where
- United Kingdom
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Swansea University
Obesity
Effect of Hydroxychloroquine Sulphate in Healthy Lean Females
The effect of an acute administration of hydroxychloroquine sulphate will be investigated on hedonic food intake, appetite related sensations and gastrointestinal hormone release in healthy female subjects.
- Trial name
- PLAQHV (NCT04005768)
- Testing
- Hydroxychloroquine Sulphate
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Satiety
Protein Intake and Satiety: a Postprandial Study
Obesity is considered the emerging epidemic of the 21st century, becoming one of the major public health problems. Excessive body weight increases morbidity and mortality risk, while decreases the quality of life and expectance.
- Trial name
- NCT04210544
- Testing
- Experimental dietary protein, Casein, Water
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Obesity
Effect of Ghrelin on Glucose Metabolism After Bariatric Surgery
The purpose of this study is to determine if the altered nutrient exposure to the GI tract after bariatric surgery reveals a negative incretin effect of ghrelin.
- Trial name
- NCT02953587
- Testing
- Oral Glucose Tolerance Test (OGTT), Human Ghrelin, Saline
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Vanderbilt University Medical Center
Frailty in Aging
Ghrelin Repeated Dose Study
Frailty is a geriatric syndrome leading to physical deterioration including muscle wasting (sarcopenia) and unintentional weight loss. There are currently no approved therapies for frailty.
- Trial name
- GRD (NCT01833078)
- Testing
- ghrelin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Pennsylvania
Esophageal Neoplasms, Stomach Neoplasms
Food Intake and Gut Hormones in Patients Who Have Undergone Upper Gastrointestinal Surgery for Cancer
Improvements to treatment strategies for patients upper gastrointestinal cancers have produced an increasing population of people who remain free from disease recurrence in the long term.
- Conditions
- Esophageal Neoplasms, Stomach Neoplasms, Weight Loss, Malnutrition
- Trial name
- NCT02385617
- Testing
- Octreotide
- Where
- 2 sites in Ireland, Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- St. James's Hospital, Ireland
the Diabetic Process
Deacylated Ghrelin and Beta Cell Function
Use of human unacylated ghrelin (UAG, also called des-octanoyl ghrelin) to study physiology in healthy subjects. The proposed research is an investigator-initiated study funded by the National Institutes of Health designed to…
- Trial name
- UAG (NCT01531283)
- Testing
- unacylated ghrelin, acyl ghrelin, combined acyl and desacyl ghrelin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- David Dalessio
Obesity, Childhood, Eating Behavior
Interoception and Eating Behaviors in Children
The purpose of this study is to examine how individual differences in interoception (the ability to sense, interpret, and act on bodily feelings like hunger, fullness, thirst, hot, cold, etc.) relate to eating behaviors in…
- Trial name
- I-EAT (NCT06504654)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Penn State University
Type 2 Diabetes Mellitus, Obesity
Effects of Rosiglitazone on Serum Ghrelin and Peptide YY Levels
We aimed to evaluate the effects of rosiglitazone on serum ghrelin and peptide yy levels in diabetic women.
- Trial name
- NCT00522470
- Testing
- rosiglitazone
- Where
- Turkey (Türkiye)
- Sponsor
- Baskent University
Obesity
A Comparison of the Metabolic Effects of Fructose, Glucose, High Fructose Corn Syrup and Sucrose at Normal Population Consumed Levels in Adults Aged 20-60 Years Old
The purpose of this study is to investigate the acute and chronic effects of consumption fructose containing sugars and glucose in a real word setting when consumed in a manner and amount typical in the American diet.
- Trial name
- NCT01797042
- Testing
- Dietary Compliance
- Where
- United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Rippe Lifestyle Institute
Breast Cancer Survivors
Effects of Green Coffee Extract Supplementation on Leptin, Ghrelin, Adiponectin,Anthropometric Measurements, Lipid Profile in Breast Cancer Survivors
To study the effects of green coffee supplement on leptin, adiponectin, ghrelin, anthropometric measurements, lipid profile in breast cancer survivors.50 breast cancer survivors who their treatment is over and referred to follow…
- Trial name
- NCT03394690
- Testing
- green coffee, control
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- National Nutrition and Food Technology Institute