Clinical trials: Gingiva Disorder
Dental Plaque and Gingivitis
The Comparative Effects of Using 0.12% Chlorhexidine and Silver Nanoparticles Mouthwashes in Medical Students
This double-blind, randomized intervention study aims to evaluate and compare the efficacy of 0.12% Chlorhexidine (CHX) mouthwash and Nano Silver (AgNPs) mouthwash.
- Trial name
- mouthwash (NCT06963788)
- Testing
- Chlorhexidine 0,12%, 0,9% Chloride Sodium, Silver nanoparticles mouthwash
- Where
- Vietnam
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Gum Bleed
Sulcular Bristle Tip Technique (SBTT) With an Electric Toothbrush
In this study, all subjects will be given an electric toothbrush. Half of the participants will be instructed on how to use the Sulcular Bristle Tip Technique (SBTT).
- Trial name
- NCT04427397
- Testing
- Sulcular Bristle Tip Technique (SBTT)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Tufts University
Gingivitis, Plaque
COMORAL® the Oral Irrigation Unit Clinical Trial
This is a clinical study to evaluate the safety and effectiveness of COMORAL®, the intraoral water-spraying cleaning device that is developed to remove plaque around teeth in the oral cavity.
- Trial name
- COMORAL (NCT05031260)
- Testing
- applying COMORAL®
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gingival Recession
Clinical Comparison Between Two Surgical Techniques for the Treatment of Gingival Recessions
The aim of this study is to test a surgical technique for the treatment of gingival recessions. The hypothesis of the study is to promote greater root coverage and better healing.
- Trial name
- NCT01175720
- Testing
- Periodontal surgery to gingival recessions
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Breast Cancer, Gingivitis
Assessment of Periodontal Therapy and Biofilm Management in Breast Cancer
Objective: To evaluate the impact of chemotherapy on periodontal conditions, hematology, and salivary flow in patients with breast cancer and gingivitis, after basic periodontal therapy (BPT).
- Conditions
- Breast Cancer, Gingivitis, Periodontal
- Trial name
- BREASTCANCER (NCT06212908)
- Testing
- Basic Periodontal Therapy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Periodontoclasia, Gingiva; Injury
Use of Injectable-platelet-rich-fibrin (I-PRF) to Thicken Gingival Phenotype
The main objective of this study is to investigate whether the for individuals with thin gingival thickness who are susceptible to gingival recession, the investigators will use i-PRF with microneedle to increase gingival…
- Conditions
- Periodontoclasia, Gingiva; Injury, Condition, Blood Clot
- Trial name
- NCT03274674
- Testing
- I-PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Gingivitis
Clinical Effectiveness of 5 Different Mouthwashes in the Treatment of Generalised Gingivitis
The aim of the present study is to evaluate the efficacy of 5 mouthwashes, based on different ingredients, in the treatment of generalised gingivitis.
- Trial name
- NCT04733196
- Testing
- Essential oils, Essential oils in combination with chlorhexidine 0,12%, Chlorhexidine 0,20 % in combination with aroma oils
- Where
- Bulgaria
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Gingival Recession
A Pilot Clinical Trial of Gintuit (TM)in Establishing a Functional Zone of Attached Gingiva
The purpose of this study is to evaluate the safety and efficacy of Gintuit compared to a free autogenous graft using donor tissue harvested from the subject's palate in the treatment of subjects who have an insufficient zone of…
- Trial name
- NCT01547962
- Testing
- Gintuit, autologous Free Gingival Graft (FGG)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Organogenesis
Gingival Recession
Effect of Hyaluronic-acid on the Healing After Free Gingival Graft
This study evaluated the effect of topical hyaluronic acid (HA) application on free gingival graft (FGG) donor and recipient sites during the early wound healing period with laser Doppler flowmetry (LDF) and to investigate the…
- Trial name
- NCT03871218
- Testing
- Hyaluronic acid group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Temporomandibular Joint Disorder
The Effect of Prolonged Sugar-Free Chewing Gum Mastication on Self-Reported Fatigue Levels and Changes of Static and Dynamic Surface Electromyography Parameters in Young Individuals With and Without Temporomandibular Joint Disorders.
This case-control study investigates fatigue induced by prolonged gum mastication in individuals with temporomandibular disorders (TMD).
- Trial name
- NCT07273123
- Testing
- Mastication of sugar-free chewing gum
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Milan
Periodontitis, Periodontitis (Stage 3)
Evaluation of Albumin Platelet-Rich Fibrin Following SRP in Patients With Periodontitis
The study aims to investigate whether application of albumin platelet-rich fibrin (Alb-PRF) into the gum pockets after scaling and root planing (SRP) can improve healing in patients with Stage III Grade B periodontitis.
- Trial name
- NCT07363135
- Testing
- Albumin platelet-rich fibrin, Sterile saline (0.9%)
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Saglik Bilimleri Universitesi
Dental Plaque, Gingivitis
Essential Oil+ELA, Plaque and Gingivitis
A commercially available mouth rinse with ethyl lauroyl arginate and essential oils claims to have enhanced antimicrobial properties as compared to the traditional essential oil products.
- Trial name
- NCT02884817
- Testing
- Experimental: essential oils and ELA, Water
- Where
- Norway
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Chronic Periodontitis, Type 2 Diabetes
The Periodontal Disease and Diabetes Mellitus Interrelationship Among Adult Malaysians
Periodontitis, a chronic inflammatory disease which results in irreversible attachment loss, bone destruction and tooth loss, is a major oral health problem affecting 90.2% of Malaysian population.
- Trial name
- NCT01951547
- Testing
- Nonsurgical periodontal therapy, Oral hygiene instructions
- Where
- Malaysia
- Volunteers
- 40 people
- Sponsor
- University of Malaya
Pregnancy, Periodontal Disease
Effectiveness of Coenzyme Q10 and Probiotics in Periodontal Therapy During Pregnancy
This randomized controlled clinical trial aims to evaluate the effectiveness of adjunctive coenzyme Q10 and probiotic supplementation (Limosilactobacillus reuteri Prodentis®) in improving periodontal health in pregnant women…
- Conditions
- Pregnancy, Periodontal Disease, Gingivitis, Dental Plaque
- Trial name
- PREG-Q10 (NCT07029360)
- Testing
- Limosilactobacillus reuteri Prodentis®, Coenzyme Q10 Toothpaste
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Tinnitus, Chronic Subjective Tinnitus
Acute Nicotine Gum and Tinnitus Loudness in Non-Smoking Adults
This study tested whether a single dose of nicotine gum can reduce the loudness of tinnitus (ringing in the ears) in non-smoking adults with chronic tinnitus.
- Trial name
- NCT07772089
- Testing
- Nicotine polacrilex gum 4 mg
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- San Diego State University
Gingival Disease, Oral Disease
Impact of an Educational Program on Gingival Status and Oral Health Related Quality of Life
This research targets the evaluation of the impact of oral health educational programs on the gingival status and oral health related quality of life in early adolescence of the Egyptian population.
- Trial name
- NCT03723174
- Testing
- Oral Health Educational Program
- Where
- Egypt
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpal Inflammation, Dental Caries
Effect of Different Heating Protocols of Resin Composites on Pulp Condition (Randomized Controlled Trial)
This randomized controlled clinical trial evaluates the effect of different resin composite preheating protocols on pulpal inflammation and postoperative pain.
- Conditions
- Pulpal Inflammation, Dental Caries, Postoperative Pain
- Trial name
- NCT07720999
- Testing
- Arm 1 only "VisCalor Thermoviscous Bulk-Fill Composite", Tetric EvoCeram Conventional Nanohybrid Composite (Preheated 55°C), Tetric EvoCeram Conventional Nanohybrid Composite (Room Temperature)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Plaque Induced Gingivitis, Mouth Diseases
Anti-inflammatory and Anti-plaque Efficacies of Mouth Rinse Containing Hyaluronic Acid and Hydrogen Peroxide
The goal of this clinical trial is to test efficiency of using mouth rinse containing (H2O2 and HA) over a period of two weeks to control on gingival inflammation and plaque accumulation through measuring the clinical periodontal…
- Conditions
- Plaque Induced Gingivitis, Mouth Diseases, Bleeding Gum, Periodontal Diseases
- Trial name
- NCT05787600
- Testing
- Perhyal rinse, Chlorhexidine mouthwash
- Where
- Iraq
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Sensitive Gum, Gum Inflammation
Usage Test on a New Cosmetic Product: Mouthwash
The goal of this clinical trial is to learn if a new mouthwash can help soothing oral mucosa in adult patients with sensitive gums.
- Trial name
- NCT06808711
- Testing
- Buccocéan mouthwash, Marketed mouthwash
- Where
- France
- Volunteers
- 50 people
- Sponsor
- YSLab
Chronic Peridontitis Patients, Chronic Gingivitis
Effect of Non-surgical Periodontal Therapy on Gingival Crevicular Fluid Interleukin-21 Levels
Human IL-21 is present in gingival crevicular fluid in periodontal health, gingivitis and chronic periodontitis. A significant increase in the concentration of IL-21 in gingival crevicular fluid is observed with an increase in…
- Conditions
- Chronic Peridontitis Patients, Chronic Gingivitis, Healthy
- Trial name
- NCT02861937
- Testing
- non surgical periodontal therapy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
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