Clinical trials: Gingiva Disorder
Periodontal Diseases, Gingivitis
Asprosin, Adropin, Irisin Levels in Periodontitis
The recently discovered association of the hormones 'asprosin, adropin and irisin' with obesity and metabolic status, as well as the fact that periodontal diseases are affected by obesity and nutrition bilaterally, have led us to…
- Conditions
- Periodontal Diseases, Gingivitis, Obesity
- Trial name
- NCT06250764
- Testing
- Clinical periodontal measuremenets, ELISA test from gingival crevicular fluid (GCF)
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- AYSAN LEKTEMUR ALPAN
Gingivitis
A Study of the C3 Complement Inhibitor AMY-101 in Adults With Gingivitis
A Phase 2a Clinical Trial to Assess the Safety and Efficacy of Complement 3 Inhibitor Analog, AMY-101, in Adults with gingivitis.
- Trial name
- NCT03694444
- Testing
- AMY-101, Water for injection
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Amyndas Pharmaceuticals S.A.
Gingival Inflammation
Gingival Irritation Due to Bleaching Tray Design in an At-home Bleaching Treatment
The primary aim of this study is to assess whether the design of the bleaching tray used in at-home bleaching treatment is directly correlated with the risk of gingival irritation.
- Trial name
- NCT06371664
- Testing
- Conventional Tray (1 mm), Extended Tray (3 mm)
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Plaque, Gingivitis
Antiplaque/Antigingivitis Efficacy of Essential Oil Mouthrinses in Six-Month Study
The objective of this randomized, single-center, examiner-blind, controlled, parallel group, six-month clinical study is to compare the antiplaque/antigingivitis potential of a no-alcohol essential oil containing mouthrinse and…
- Conditions
- Plaque, Gingivitis, Gum Inflammation, Bleeding
- Trial name
- NCT02980497
- Testing
- Listerine Zero Mouthwash (without alcohol), Listerine Antiseptic Mouthwash (with alcohol)
- Where
- Brazil
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Epulis
Histological/ Immunohistological and Molecularpathological Types of Epulides and Central Giant Cell Lesions of the Jaws
This retrospective study will evaluate the patient collective of the Division of Oral Surgery and Orthodontics, Department of Dental Medicine and Oral Health and of the Division of Cranio-Maxillofacial Surgery at the Medical…
- Trial name
- NCT03829059
- Where
- Austria
- Volunteers
- 83 people
- Sponsor
- Medical University of Graz
Dental Plaque
Effect of Enzymes on Dental Biofilm Accumulation in Healthy Individuals
The purpose of the study is to assess the effect of enzyme containing lozenges on dental plaque accumulation in healthy adults.
- Trial name
- NCT05082103
- Testing
- Enzyme lozenge 1, Enzyme lozenge 2
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Periodontitis, Periodontal Diseases
Vitamin D Supplementation Prior to Non-surgical Periodontal Therapy
The purpose of this study is to test the feasibility i. e. to examine all aspects necessary for the implementation of a future randomized clinical trial (RCT) that aims to determine whether non-surgical periodontal treatment can…
- Conditions
- Periodontitis, Periodontal Diseases, Periodontal Inflammation, Inflammation
- Trial name
- NCT05398770
- Testing
- Vitamin D supplementation (30 µg/d)
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- University of Tromso
Periodontitis, Treatment Adherence
I-Smads in Periodontitis
Recently, it has been stated that Smads play an active role in all conditions where transforming growth factor-beta (TGF-β) is involved, including periodontal inflammation.
- Trial name
- NCT04846166
- Testing
- Periodontally healthy group, Periodontitis
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Gingival Recession, Localized
Impact of Microneedling on Coverage of RT1 Gingival Recession in Thin Phenotype.
Gingival Recession (GR) is a common finding among adults, regardless of the oral hygiene levels. When it is associated with esthetic impairment, dentin hypersensitivity, root caries, surgical treatment is indicated.
- Trial name
- NCT06432439
- Testing
- microneedling followed by CAF procedures, CAF procedure
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Recession, Localized, Sensitivity, Tooth
Two Different Graft Harvesting Techniques Applied in Localized Gingival Recessions
The primary purpose of this study is to compare the root coverage rate of the gingival unit-shaped connective tissue graft, obtained by intraoral de-epithelization, with the traditional de-epithelialized free gingival graft in…
- Conditions
- Gingival Recession, Localized, Sensitivity, Tooth, Attachment Loss, Periodontal
- Trial name
- NCT05923294
- Testing
- Coronally advanced flap with connective tissue graft
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Gingival Recession
Ultrasonic vs Radiographic Measurement of Gingival Biotype. A Novel Method
This clinical study consists on taking 2 different records of the upper and lower incisors area : 1) a perpendicular x-ray and 2) an ultrasonic measurement of gingival thickness on the labial plate.
- Trial name
- NCT03735394
- Testing
- ultrasonic probe
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Oral Biofilm, Periodontitis
Methodology Antiseptic Application, Influence on Oral Biofilm.
The study has the objective to compare two different methodology of application the antiseptic on the oral biofilm will be formed during 48h in situ on a specific device.
- Conditions
- Oral Biofilm, Periodontitis, Gingivitis
- Trial name
- NCT02267239
- Testing
- essential oils, immersion, Chlorhexidine, immersion, essential oils, mouthwash
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Nitric Oxide, Vasodilation
Evidence of Spreading Vasodilation in Human Gingiva
The aim of this study is to observe the mechanism of spreading vasodilatation on human healthy gingiva. Nitric-oxide donor solutions in lower and higher concentration are used to trigger the vasoactivity.
- Conditions
- Nitric Oxide, Vasodilation, Oral Soft Tissue Conditions
- Trial name
- NCT03605095
- Testing
- nitroglycerin
- Where
- Hungary
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Gingival Recession
Composite Resin Plus Connective Tissue Graft.
The aim of the present study is to evaluate the clinical, aesthetic and patient-centered parameters of connective tissue graft associated or not with composite resin for the treatment of gingival recession.
- Trial name
- NCT02423473
- Testing
- Connective tissue graft, Composite resin restoration (Filtek Supreme - 3M)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Gingivitis, Dental Plaque
Pooled Analysis of Clinical Data From Six GSK Studies to Investigate the Efficacy of a Dentifrice Containing 67% Weight by Weight (w/w) Sodium Bicarbonate on Gingivitis and Plaque Accumulation
The aim of this analysis was to pool data from 6 GSK studies with similar clinical design to investigate the overall efficacy of a test dentifrice containing 67% w/w sodium bicarbonate in the treatment of gingivitis and plaque…
- Trial name
- NCT03703245
- Testing
- Sodium bicarbonate, Control Dentifrice
- Where
- United Kingdom
- Volunteers
- 1,601 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Paralytic Ileus
Gum Chewing Reduces the Risk of Postoperative Ileus After Arthroplasty Procedures in The Elderly Population
Postoperative ileus (POI) is defined as a temporary cessation of bowel movement after a surgical procedure. Surgical procedures not only include abdominal or colorectal procedures but non-abdominal procedures as well.
- Trial name
- NCT04489875
- Testing
- Chewing Gum
- Volunteers
- 50 people
- Sponsor
- Indus Hospital and Health Network
Mouth Diseases, Bleeding Gum
The Impact of Ginger Mouthwash on the Pregnant Women With Stress and Gingivitis
The study aims to determine ginger mouthwash's impact on gingival health, IL-6, cortisol, LF, and 8-OHdG levels in pregnant women with stress and gingivitis compared to CHX and distilled water. Objectives: 1.
- Conditions
- Mouth Diseases, Bleeding Gum, Stress
- Trial name
- NCT06792812
- Testing
- ginger mouthwash, chlorohexidine mouthwash
- Where
- Iraq
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Gingival Recession, Localized
Effectiveness of Modified-free Gingival Graft for Treatment of Localized Gingival Recession Defects
The aim of the present study is to evaluate, whether use of the modified free gingival graft (mod-FGG) technique improves treatment outcomes after surgical root coverage at mandibular incisors with gingival recession defects.
- Trial name
- NCT04718545
- Testing
- Mucogingival surgery
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Göteborg University
Gingivitis
Artificial Intelligence for the Diagnosis of Gingivitis
this study aims to use AI to diagnose the stages of gingivitis
- Trial name
- NCT07727421
- Testing
- Artificial intelligence Diagnostic Model
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Abfraction
Treatment of NCCL Asociated With Gingival Recession With B.O.P.T. Technique
The purpose of this clinical trial is to evaluate the gingival margin changes resulting from the treatment with biologically oriented preparation technique (B.O.P.T.) of non-carious cervical lesions (NCCL).
- Trial name
- NCT05861193
- Testing
- Treatment of the abfraction with BOPT technique
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Valencia
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.