Clinical trials: Gingiva Disorder
Plaque, Gingivitis
Safety and Tolerability of Antiplaque Chewing Gum in a Gingivitis Population
This study is to assess the safety and tolerability of single doses and multiple doses in reducing plaque and gingivitis when delivered in a chewing gum formulation.
- Trial name
- APCG (NCT01877421)
- Testing
- 2 mg KSL-W, 4 mg KSL-W, 6 mg KSL-W
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Peri-Implantation Loss, Periodontal Bone Loss
The Rehabilitation of Atrophic Jaws Using Short Implants With Different Surface Characteristics
The aim of the research is to evaluate the clinical outcome of short dental implants, characterized by a new macro-structural design and inserted in the upper or lower jaw in patients with reduced bone volume.
- Conditions
- Peri-Implantation Loss, Periodontal Bone Loss, Periimplantitis, Gingival Inflammation
- Trial name
- NCT05766878
- Testing
- implants placement
- Where
- 3 sites in Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Melanin Hyperpigmentation
Melanin Recurrence in Scalpel and LASER Gingival Depigmentation in Thin and Thick Phenotypes.
This study aimed to compare melanin pigmentation recurrence, pain perception and wound healing between laser and scalpel surgeries in thin and thick gingival phenotypes.Thirty patients (60 sites) were included in this study.
- Trial name
- NCT06886100
- Testing
- Diode laser, Scalpel No 15
- Where
- Yemen
- Volunteers
- 30 people
- Sponsor
- Thamar University
Obesity, Obesity, Childhood
Associations Between Obesity, Dental Caries, Erosive Tooth Wear and Periodontal Disease in Adolescents: A Case Control-study
Objectives To compare oral health (dental caries, periodontal status, and erosive tooth wear (ETW)), diet and oral hygiene habits between obese and normal weight adolescents, and to explore possible risk associations.
- Conditions
- Obesity, Obesity, Childhood, Tooth Wear, Tooth Erosion
- Trial name
- NCT05146557
- Testing
- Dental examination
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University Ghent
Gingival Recession, Mucogingival Surgery
Microsurgical Instruments and Magnification May Enhance Treatment Outcomes Of Laterally Moved, Coronally Advanced Flap in Miller Class III Isolated Recession Defects
The benefits of microsurgical approaches in periodontal therapy have been described. The main focus of this study is to determine if using microsurgical LMCAF technique would improve the outcomes of the therapy for the Miller…
- Trial name
- NCT02281071
- Testing
- laterally moved coronally advanced flap with microsurgical instruments and x2.5 loupe
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Stage II Grade B Periodontitis
Active Oxygen Gel vs Chlorhexidine Gel in Stage II Grade B Periodontitis
This randomized controlled clinical trial will evaluate the effectiveness of locally delivered active oxygen gel and chlorhexidine gel as adjuncts to scaling and root planing in the treatment of stage II grade B…
- Trial name
- NCT07840716
- Testing
- Active oxygen gel, Chlorhexidine gel
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Dental Plaque, Gingivitis
The Clinical Efficacy of Three Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste and a Mouthwash in Controlling Dental Plaque and Gingivitis
The objective of this clinical research study is to assess the efficacy of three oral hygiene multi-component regimens encompassing the use of a manual toothbrush, toothpaste and a mouthwash in controlling established dental…
- Trial name
- NCT02193165
- Testing
- triclosan/fluoride toothpaste + cetylpyridinium chloride Mouthwash, stannous fluoride toothpaste + cetylpyridinium chloride Mouthwash, fluoride toothpaste + fluoride Mouthwash
- Where
- Puerto Rico
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingival Recession
Coronally Advanced Flap and PRF With or Without Demineralized Freeze-dried Bone Allograft in Gingival Recession
Gingival recession is defined as the apical migration of gingival margin beyond cemento-enamel junction with the exposure of root surface.
- Trial name
- NCT02835430
- Testing
- Coronally advanced flap and PRF with DFDBA, Coronally advanced flap and PRF without DFDBA
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Periodontitis, Gingivitis
GCF Bax and Bcl-xl Levels in Periodontitis
Intrinsic apoptosis pathway plays a critical role in the host immune defense and inflammation and its dysregulation is involved in various chronic diseases. Bcl-2 protein family primarly mediates this mitochondrial pathway.
- Conditions
- Periodontitis, Gingivitis, Periodontal Health
- Trial name
- NCT06443372
- Testing
- Clinical periodontal measurements, GCF sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Gingivitis, Gingivitis and Periodontal Diseases
Evaluation of the Effect of a Toothpaste Containing 0.3% Chlorhexidine in Subjects With Established Dental Plaque and Gingivitis
This is a Phase III, one-center, parallel group, double blind, clinical study to evaluate the effect of a toothpaste containing 0.3% chlorhexidine in subjects with established dental plaque and gingivitis.
- Conditions
- Gingivitis, Gingivitis and Periodontal Diseases, Gingival Disease, Dental Plaque
- Trial name
- CHX TP (NCT06732466)
- Testing
- Chlorhexidine toothpaste, Toothbrush
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Colgate Palmolive
Plaque, Dental
Anti-bacterial Clinical Study on Teeth, Tongue, Cheek, Gum, and Saliva
This 4-week clinical study was designed to examine the antibacterial efficacy of brushing with a 0.454% stannous fluoride toothpaste with potassium nitrate and pyrophosphate compared to a toothpaste containing 0.76% MFP (marketed…
- Trial name
- NCT06353165
- Testing
- Stannous fluoride toothpaste, Colgate Dental Cream
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingival Recession, Generalized
Comparison of De-Epithelialized Gingival Graft With or Without Platelet Rich Fibrin in Multiple Gingival Recessions
The aim of this study is to compare the clinical efficacy and patient reported outcome measures of de-epithelialized gingival graft (DGG) with or without platelet rich fibrin on treatment of multiple adjacent gingival recessions…
- Trial name
- NCT06509867
- Testing
- DGG, Platelet rich fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Postoperative Sore Throat
Effect of Chewing Gum and Mouthwash Before Operation on Sore Throat After General Anesthesia With a Laryngeal Mask
Postoperative sore throat (POST) is an important problem after general anaesthesia. We assessed whether chewing gum preoperatively or mouthwash can reduce the incidence of POST after general anaesthesia administered via a…
- Trial name
- NCT04644900
- Testing
- chewed mint gum, Mouthwash
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Fudan University
Gingival Recessions
Guided Versus Non-Guided Harvesting Technique of Soft Tissue Graft in Cairo Recession Type I Sites
The goal of this clinical trial is to compare the healing pattern in the palate following harvesting of deepithelialized free gingival graft by two different harvesting techniques and to compare the recession coverage at the…
- Trial name
- RCT (NCT06603467)
- Testing
- non-guided de-epithelialized free gingival graft harvested, guided de-epithelialized free gingival graft harvested
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Recession, Gingival
Long-term Outcomes of Tunnel Technique
Few studies evaluate the outcomes beyond 1 year follow up for gingival recessions treatments using the tunnel technique in combination with connective tissue graft.
- Trial name
- NCT04016493
- Testing
- Connective tissue graft
- Volunteers
- 40 people
- Sponsor
- University of Liege
Gingivitis, Supragingival Plaque
Evaluation of the Efficacy and Safety of a Loop Stretchable Dental Floss
This will be a single-blind, single-center, parallel, randomized controlled clinical trial to evaluate the efficacy and safety of Floss Loops stretchable floss for the control of gingivitis and supragingival plaque removal…
- Trial name
- NCT06515483
- Testing
- Brushing and Flossing of teeth, Brushing Only
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pain, Postoperative, Gingival Diseases
Effect of Using Placental Membranes on Healing and Post-op Pain After Gum Surgery
When harvesting autogenous free grafts to treat periodontal conditions (e.g., lack of attached keratinized tissue, ridge defects, and other mucogingival deformities), the hard palate is the preferred donor site.
- Trial name
- NCT04957342
- Testing
- amnion-chorion membrane, Sutures
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Specific Learning Disabilities, Dental Caries
Dental Caries and Oral Hygiene Status in Children With Specific Learning Disabilities
This study aims to evaluate dental caries and oral hygiene status in children aged 7-12 years with specific learning disabilities (SLD) and to compare the findings with healthy children.
- Conditions
- Specific Learning Disabilities, Dental Caries, Oral Hygiene
- Trial name
- SLD-OH (NCT07611981)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Gingival Overgrowth
Comparison of I-PRF, T-PRF, and 0.8% Hyaluronic Acid Applications in Wound Healing After Gingivectomy.
Objectives: This study aimed to evaluate the effect of injectable platelet-rich fibrin (i-prf), titanium-prepared platelet-rich fibrin (t-prf), and 0.8% hyaluronic acid (HA) gel on clinical periodontal parameters, wound healing…
- Trial name
- NCT06865092
- Testing
- injectable platelet-rich fibrin, titanium-prepared platelet-rich fibrin, Hyaluronic Acid (HA)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi
Gingivitis, Periodontal Infection
Intervention Study of Oral Health Education Programs Directed to Adolescents
This study evaluates behavioral interventions to increase adolescent's motivation for self performed periodontal infection control, by means of adequate oral hygiene.
- Trial name
- NCT02906098
- Testing
- Patient centered oral health education, Standard educational intervention
- Where
- Sweden
- Volunteers
- 312 people
- Sponsor
- Göteborg University
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