Clinical trials: Gingiva Disorder
Gingival Hyperplasia, Dental Plaque
Clinical Efficacy of Chlorhexidine Varnish in Reducing Gingival Hyperplasia, Plaque Accumulation, and White Spot Lesions in Orthodontic Patients
This study investigates whether applying a chlorohexidine varnish (a dental coating) reduces gum overgrowth, plaque buildup, and early tooth decay (white spots) in patients with braces.
- Conditions
- Gingival Hyperplasia, Dental Plaque, Tooth Demineralization
- Trial name
- NCT07115784
- Testing
- Chlorhexidine Varnish
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
RT II Gingival Recession
Hyaluronic Acid and Polynucleotides With Connective Tissue Graft and Coronally Advanced Flap for RT II Gingival Recession
This case series will evaluate the effectiveness of injectable hyaluronic acid combined with polynucleotides as an adjunct to coronally advanced flap and connective tissue graft in patients with RT II gingival recession.
- Trial name
- NCT07771244
- Testing
- Coronally Advanced Flap with Connective Tissue Graft and Hyaluronic Acid/Polynucleotides
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Cairo University
Gingivitis
Controlled Clinical Trial of Traditional Chinese Medicine Mouthrinse
Traditional Chinese medicine (TCM) has been seen as the predominant way of treating disease in China over three thousand years. Certain TCM have scientifically proved to have anti-bacterial property.
- Trial name
- NCT01637948
- Testing
- Listerine mouthrinse, Chinese Medicine mouthrinse
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Gingivitis, DMFT Index
Motivational Interviewing to Improve Oral Hygiene in Adolescent Orthodontic Patients
This study is being conducted to explore how motivational interviewing (MI), A patient-centered counseling method, can help improve oral health awareness and practices in adolescents undergoing orthodontic treatment.
- Conditions
- Gingivitis, DMFT Index, Dental Plaque Index, Oral Hygiene Education Methods
- Trial name
- MI-Ortho (NCT07164989)
- Testing
- Motivational Interviewing-Based Counseling, Standard Oral Health Education
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Nutritional and Metabolic Diseases, Overweight
The FaibaGo Study - Long-Term Weight Reduction Via Low-Threshold Intervention
The main aim of this study is to assess the effect of a chewing gum containing galactooligosaccharides (GOS) on the body mass index (BMI), the metabolism and the oral and intestinal microbiomes in a population of overweight…
- Trial name
- NCT07036692
- Testing
- FibreGum
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Bern
Gingival Recession
Platelet Rich Fibrin in the Treatment of Localized Gingival Recessions
The present study deals with treatment of localized gingival recessions. The hypothesis of this study is that platelet rich fibrin can be used an alternative to subepithelial connective tissue graft in the coverage of denuded…
- Trial name
- NCT01793389
- Testing
- Subepithelial connective tissue graft, Platelet Rich Fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ege University
Gingivitis, Plaque
Clinical Study of Toothpaste Containing Zinc Lactate as Compared to Colgate Cavity Protection Toothpaste.
The objective of this six-month clinical research study is to evaluate the clinical efficacy of two dentifrices - Toothpaste containing zinc lactate and Colgate Cavity Protection Toothpaste in reducing gingivitis and dental…
- Trial name
- NCT06563518
- Testing
- Meridol, Colgate Cavity Protection
- Where
- Thailand
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Pregnancy Gingivitis, Ozone
Ozone Therapy for the Home Oral Hygiene of the Pregnant Woman.
The aim of the present study is analyzing the effect of an domestic ozonated water delivering device on the oral health status of pregnant women.
- Trial name
- NCT04140643
- Testing
- Ozonated water delivering device effects on the oral health of pregnant women, Oral hygiene instructions
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Gingival Recession
Manual Versus Oscillating-rotating Toothbrushes After Root Coverage Procedure
The aim of this study is to evaluate the gingival margin stability with the use of oscillating-rotating toothbrushes compared to manual toothbrushes.
- Trial name
- NCT02534220
- Testing
- Manual Toothbrush, Oscillating-rotating toothbrush
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Milan
Age Problem
Gingivitis Treated With Chlorhexidine 0.12% Mouthwash in Young Adults
The aim of this study will evaluate the effectiveness of 0.12% chlorhexidine solution as an anti-inflammatory agent and reducing the presence of biofilm in young adults.
- Trial name
- NCT04658225
- Testing
- 0.12% chlorhexidine
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal Fluminense
Gingivitis, Oral Health
Frequency of Self-performed Mechanical Control of Plaque
The purpose of this blind randomized clinical trial is to evaluate different frequencies in self-mechanical control of plaque in individuals with historic of periodontitis and in periodic and preventive maintenance in order to…
- Trial name
- NCT02684682
- Testing
- Frequency of mechanical control of plaque (12h), Frequency of mechanical control of plaque (24h), Frequency of mechanical control of plaque (48h)
- Where
- Brazil
- Volunteers
- 39 people
- Sponsor
- Universidade Federal de Santa Maria
Psoriasis, Periodontal Diseases
Interleukin- 17 (IL-17), Bcl-3, and NF-kappa-B Inhibitor Zeta (IκBζ) Expression Levels in the Psoriasis Patients
This study aimed to compare the levels of IL-17 (interleukin- 17), Bcl-3 (B-cell lymphoma 3-encoded protein), and IκBζ (NF-kappa-B inhibitor zeta) in the gingival crevicular fluid of psoriatic and healthy individuals and the…
- Trial name
- NCT06408454
- Testing
- Gingival crevicular fluid collection, periodontal test
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Gingival Recession
Single Stage Root Coverage for Gingival Recession With or Without Free Gingival Graft
Background and Objective: Gingival recession accounts for apical migration of the gingival margin resulting in exposure of the cementoenamel junction (CEJ) and root surface.
- Trial name
- NCT03370042
- Testing
- semilunar coronally positioned flap with free gingival graft, semilunar coronally positioned flap alone
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kamineni Institute of Dental Sciences
Gingival and Periodontal Disease, Deficiency of Vitamin D3
Study of Vitamin D Supplementation on Improvement of Gums Health
There is a gap in knowledge regarding the effects of Vitamin D supplementation on periodontal status in pregnant wome. The investigators aim to evaluate the potential benefit, if any of vitamin D supplementation during pregnancy…
- Conditions
- Gingival and Periodontal Disease, Deficiency of Vitamin D3, Pregnancy
- Trial name
- VitaminD (NCT01422122)
- Testing
- Vitamin D3
- Where
- Pakistan
- Volunteers
- 115 people
- Sponsor
- Aga Khan University
Gingival Recession
Gingival Augmentation and Root Coverage With Superficial and Deep Cut Acellular Dermal Matrices
This entire protocol involves procedures that are standard care and will randomize subjects to of one two routine care procedures. Patients needing root coverage for gingival recession will be enrolled.
- Trial name
- NCT05956496
- Testing
- Allograft Material ADM-S, Allograft Material ADM-D
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Gingival Diseases
Coronally Advanced Flap With Two Different Techniques for the Treatment of Multiple Gingival Recessions
This study compared the clinical outcomes of coronally advanced flap using two different surgical strategies in the treatment of multiple gingival recessions.
- Trial name
- NCT02229669
- Testing
- Horizontal incisions, Oblique incisions
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Paulista University
Pain Management
Effect of Chewing Different Flavor Gum on Procedural Pain and Fear
Needle-related pain and anxiety present persistent challenges in pediatric clinical procedures. This study aims to investigate the effects of chewing sugared and sugar-free gum on pain, anxiety, and fear in children undergoing…
- Trial name
- Gum-Pain (NCT07326254)
- Testing
- Sugared Gum Chewing, Sugar-Free Gum Chewing, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Gingivitis, Periodontal Diseases
Changes in Oral Health in Tobacco Cigarettes Smokers After Switching to Combustion-Free Nicotine Delivery Systems
Although the well-known detrimental effects of conventional cigarette smoking on oral health, there are still lack of evidences about the impact of less harmful alternatives (such as electronic cigarettes or heat not burn…
- Trial name
- SMILE (NCT04649645)
- Testing
- TOBACCO CIGARETTES, COMBUSTION-FREE NICOTINE DELIVERY SYSTEMS (C-F NDS), NOT SMOKING
- Where
- Italy
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Eclat Srl.
Gingival Recession Generalized Moderate
The Use of Coronary Displaced Flap and Deepithelialized Free Graft in the Treatment of Multiple Gingival Recessions
Successful treatment of multiple gingival recessions (MRG) is a major challenge in periodontal plastic surgery due to complicated predisposing anatomical features of the surrounding tissues, such as a thin gingival phenotype or a…
- Trial name
- NCT05664373
- Testing
- Coronally advanced flap and deepithelized free gingival graft
- Where
- Serbia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Gingivitis, Gum Disease
Efficacy of Devices in Maintaining Oral Health and Managing Periodontal and Interproximal Tissues
The aim of the study was to assess the acceptability of the assisted individual and compliance with home use, as well as their clinical impact on the plaque index (PI) and bleeding on probing (BOP), with monthly reassessments…
- Conditions
- Gingivitis, Gum Disease, Oral Health
- Trial name
- NCT07520994
- Testing
- Group 1: use of the rubber interdental brush (picks) at baseline for 3 months, Group 2: use of the traditional bristle interdental brush at baseline for 3 months
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Roma La Sapienza
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