Clinical trials: Gingiva Disorder
Periodontal Diseases, Gingivitis
Comparative Evaluation of Antiplaque and Antigingivitis Efficacy of Ocimum Sanctum (Tulsi) Extract
Chlorhexidine is considered as gold standard for its antiplaque and antigingivitis efficacy till date but it has got many side effects.
- Conditions
- Periodontal Diseases, Gingivitis, Periodontitis
- Trial name
- NCT03474146
- Testing
- Ocimum sanctum, Chlorhexidine Gluconate, Propylene Glycol
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government College of Dentistry, Indore
Periodontal Diseases
Periodontal Disease Prediction System
The purpose of this study was to develop a periodontal disease prediction software and a patient-based gingival recession simulator for clinical practice aiming at improving oral hygiene motivation of patients with periodontal…
- Trial name
- NCT05809570
- Testing
- Clinical examination
- Where
- Turkey (Türkiye)
- Volunteers
- 1,057 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Gingivitis; Chronic, Gingivitis and Periodontal Diseases
Comparision of Enzymatic and Active Salt Toothpaste
Dental plaque is a major etiological factor in the development of gingivitis. Mechanical plaque control through toothbrushing is essential for maintaining oral hygiene, while toothpaste formulations containing active ingredients…
- Conditions
- Gingivitis; Chronic, Gingivitis and Periodontal Diseases, Dental Plaque
- Trial name
- Enzyme T/P (NCT07880483)
- Testing
- Enzyme toothpaste, active salt toothpaste, standard fluoridated toothpaste
- Where
- India
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Uttar Pradesh University of medical sciences
Gingival Recession, Xenograft Model
Two Different Surgical Techniques for the Treatment of Multiple Gingival Recessions With Porcine Collagen Matrix
The gold standard for gingival recession treatment is the coronal repositioning of the flap associated with the subepithelial connective tissue graft.
- Conditions
- Gingival Recession, Xenograft Model, Gingival Recession, Generalized
- Trial name
- NCT03619096
- Testing
- tunnel technique for Root coverage with Porcine collagen Matrix, extended fla technique for Root coverage with Porcine collagen Matrix
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dentinal Hypersensitivity
Comparison Of Clinical Efficacy Of A Herbal And A Non-Herbal Mouthwash On Dentinal Hypersensitivity
Aim of this study was to assess and compare the efficacy of a commercially available novel herbal mouthwash containing potassium nitrate on Dentinal Hypersensitivity (DH) compared to a placebo and non herbal potassium nitrate…
- Trial name
- NCT02008500
- Testing
- Herbal Mouthwash, Non Herbal Mouthwash
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Periodontitis, Periodontal Inflammation
GCF Galectin-3 and Interleukin-1beta Levels in Periodontitis.
This study aims to evaluate gingival crevicular fluid Galectin-3 and Interleukin-1beta levels in different grades (B and C) of stage 3 periodontitis, concurrently, and also to investigate their discriminative efficiencies in…
- Trial name
- NCT05449093
- Testing
- Periodontal clinical measurements and gingival crevicular fluid sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Gingival Recession, Generalized
Comparison Between Connective Graft and Xenogeneic Matrix, in Patients With Multiple Gingival Recessions
Subepithelial connective tissue graft (SCTG) is considered the gold standard for root coverage treatment. However, it is associated with postoperative morbidity, limited amount of donor tissue, and longer surgical time.
- Trial name
- NCT03207984
- Testing
- Root coverage surgery
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Gingival Recession, Localized
Reconstruction of Deficient Interdental Papilla Using Stem Cells vs Physiological Saline
The goal of this study is to assess the reconstruction of interdental papilla following the injection of UC-MSCs or physiological saline in patients with interdental papilla deficiency.
- Trial name
- NCT06388447
- Testing
- Umbilical cord-mesenchymal stem cells
- Where
- Malaysia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Gingival Recession
Platelet Rich Fibrin on Root Coverage of Gingival Recessions
Several surgical techniques and various adjunctive agents have been used to covered Gingival Recession (GR) and promote clinical outcomes.
- Trial name
- NCT04248049
- Testing
- Platelet rich fibrin
- Where
- Colombia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universidad Antonio Nariño
Gingival Recession
Microsurgical Versus Conventional Semilunar Coronally Advanced Flap
BACKGROUND: The semilunar coronally repositioned flap (SLCRF) has been used for the treatment of recession defects (GR). Recently a microsusgical (MICRO) has been successfully employed with the procedure apparently resulting in…
- Trial name
- NCT02433899
- Testing
- MICROSURGERY, MACROSURGERY, Dexamethasone
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Periodontal Diseases
Accuracy of Assessing the Gingival Biotype in Upper Anterior in Adult Patients, Using Different Methods.
The study is a Diagnostic accuracy study that determining the accuracy of assessing the gingival biotype and some other anatomic parameters,including (crown width / crown length ratio, attached gingival width, labial bone…
- Trial name
- NCT04640506
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingivitis, Dental Plaque
A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health
The aim of this analysis was to compare gingivitis- and plaque-reduction efficacy from randomized controlled trials (RCTs) up to six months long evaluating oscillating-rotating, sonic, and manual toothbrushes
- Trial name
- NCT05594004
- Testing
- Oscillating-rotating electric toothbrush, Sonic electric toothbrush, Manual toothbrush
- Where
- United States
- Volunteers
- 2,929 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Gingival Recession
CAF With or Without CTG for the Treatment of Single Maxillary Gingival Recession With NCCL
This studies evaluate the efficacy of the coronally advanced flap (CAF) with or without connective tissue graft (CTG) for the treatment of single maxillary recession associated to non carious cervical lesion (NCCL).
- Trial name
- NCT03862534
- Testing
- CAF, CAF + CTG
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florence
Biofilm Removal, Gingival Abrasion
Capacity of Biofilm Removal and Gingival Abrasion After Utilization Medium and Soft Toothbrushes
This study compared the removal of dental biofilm between soft and medium toothbrushes. The patients refrained from performing mechanical or chemical plaque control for 96 hours to allow dental biofilm accumulation on the tooth…
- Trial name
- NCT01125007
- Testing
- Two kind toothbrushes
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Franciscan University Center
Gingivitis, Dental Plaque
Clear Aligner Cleaning: Brushing, Chlorhexidine, and BlueM Effects on Oral Microbial Ecology and Periodontal Indices
This randomized crossover study will assess how three aligner-cleaning methods affect early supragingival oral microbial ecology and periodontal health in adults using clear aligners.
- Trial name
- NCT07307716
- Testing
- Mechanical toothbrushing (fluoride toothpaste), Chlorhexidine mouthwash (0.2%), Oxygen-based cleanser
- Where
- Saudi Arabia
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Periapical Diseases
Evaluation of RANKL/OPG Levels in Gingival Crevicular Fluid at 1st and 3rd Months of Activation of NaOCl With Er,Cr YSSG Laser in Root Canal Treatment
Chronic Apical Periodontitis (CAP) is a disease caused by bacterial infection of the dental pulp and characterized by inflammation of the periradicular tissues.
- Trial name
- NCT05478811
- Testing
- Er,Cr:YSSG laser, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Gum Chewing, Sore Throat
Preoperative Gum Chewing for Different Durations to Prevent Sore Throat After Endotracheal Intubation
This study aims to evaluate the effect preoperative chewing gums for 2 or 4 minutes on postoperative sore throat after general anesthesia using an endotracheal tube.
- Conditions
- Gum Chewing, Sore Throat, Endotracheal Intubation, Randomized Controlled Trial
- Trial name
- NCT05069844
- Testing
- Gum chewing for 2 minutes, Gum chewing for 4 minutes
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Ahmed Salah Ahmed Abd Elgalil
Gingivitis, Dentin Hypersensitivity
Toothpastes With Thermal Water for Oral Health
The aim of the study is to compare the effect of toothpastes containing thermal water of Castera-Verduzan with 1450 ppm fluoride and without fluorinated derivatives on oral hygiene, gingivitis, and dentin hypersensitivity in…
- Trial name
- NCT05623761
- Testing
- BUCCOTHERM® Sensitive Gums with Fluoride, BUCCOTHERM® Sensitive Gums Fluoride-Free
- Where
- Russia
- Volunteers
- 84 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Periodontitis, Gingivitis and Periodontal Diseases
Effectiveness of Intraseptal Anesthesia for Periodontal Surgical Procedures
The primary aim of this study is to evaluate the efficacy of intraseptal anesthesia using 0.3 mL of 4% articaine with 1:100,000 epinephrine (4% Ar+Ep) for periodontal flap surgery in patients with periodontitis and for…
- Trial name
- NCT07212270
- Testing
- periodontal flap surgery, gingivectomy and gingivoplasty
- Where
- Serbia
- Volunteers
- 60 people
- Sponsor
- University of Belgrade
Paralytic Ileus
Effects of Gum Chewing on Recovery of Bowel Function Following Abdominal Surgery for Endometrial and Ovarian Cancer
Following extensive abdominal surgery for the treatment of endometrial or ovarian cancer, paralytic ileus frequently develops. Gum chewing can promotes the return of bowel function through the cephalic-vagal reflex and increased…
- Trial name
- NCT01389986
- Testing
- Gum chewing
- Where
- Thailand
- Sponsor
- Chiang Mai University
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