Clinical trials: Gingiva Disorder
Periodontitis, Gingivitis
Meteorin-like Levels in Individuals With Periodontitis
Metrnl has proven to be an inflammatory-related immunoregulatory cytokine and shown to play a role in the pathogenesis of human inflammatory diseases. Metrnl is highly expressed from the oral mucosa to the esophagus.
- Conditions
- Periodontitis, Gingivitis, Healthy
- Trial name
- NCT04402996
- Testing
- Saliva, gingival crevicular fluid
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Dental Abrasion, Gingival Recession
Evaluation of Two Resin Composites and Two Adhesives for a Novel Restorative Protocol to Treat Cervical Lesions
Non-carious cervical lesion is frequently associated with gingival recession, resulting in a combined lesion that has a different treatment prognosis when the two lesions appear alone.
- Conditions
- Dental Abrasion, Gingival Recession, Composite Resins
- Trial name
- NCT03215615
- Testing
- Periodontal surgery, Total Etch adhesive, Universal Adhesive
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Gingival Bleeding
Garlic With Lime Juice and Chlorhexidine Mouthwash
the study about herbal mouthwash. it is clinical trial .the investigator will compare between chlorhexidine mouthwash and garlic with lime juice mouthwash.and their effect on gingival bleeding and plaque and salivary bacteria.
- Trial name
- mouthwash (NCT03105960)
- Testing
- garlic with lime mouth wash, chlorhexidine
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Periodontitis, Type 2 Diabetes
The Periodontal Disease and Diabetes Mellitus Interrelationship Among Adult Malaysians
Periodontitis, a chronic inflammatory disease which results in irreversible attachment loss, bone destruction and tooth loss, is a major oral health problem affecting 90.2% of Malaysian population.
- Trial name
- NCT01951547
- Testing
- Nonsurgical periodontal therapy, Oral hygiene instructions
- Where
- Malaysia
- Volunteers
- 40 people
- Sponsor
- University of Malaya
Obesity, Overweight
Chewing Gum for Weight Loss
This is a randomized controlled trial of the effects of chewing gum on body weight. The investigators will randomly assign 200 overweight or mildly obese adults to one of two groups.
- Conditions
- Obesity, Overweight, Weight Loss
- Trial name
- NCT00971347
- Testing
- Extra sugar-free chewing gum sticks, nutrition brochure
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pregnant Woman
Pregnancy Women and Individual Oral Prophylaxis in the Control of Gingival Inflammation (PRE-IOP)
Gingivitis in pregnant women is a common inflammatory periodontal disease that appears from the third month of pregnancy with an overall prevalence of 35 to 100%.
- Trial name
- PRE-IOP (NCT05945225)
- Testing
- Sonicare DiamondClean 9000 Philips®, HydroSonic Easy Curaden®, Manual toothbrush Oral-B 123
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Claude Bernard University
Nutritional and Metabolic Diseases, Child Obesity
The FibreGum Study - Changing the Course of Obesity in Children
The aim of this study is thus to assess the effect of a chewing gum containing fibres on body weight, metabolism and the oral and intestinal microbiomes in a population of obese children.
- Conditions
- Nutritional and Metabolic Diseases, Child Obesity, Adolescent Obesity
- Trial name
- FibreGum (NCT05540678)
- Testing
- FibreGum
- Where
- 2 sites in Switzerland
- Volunteers
- 93 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Gingival Recession
Treatment Off Gingival Recession Defects Using a Xenogenic Acellular Dermal Matrix Compared to Connective Tissue Graft.
Limitation of donor site and significant postoperative morbidity are often described in connective tissue graft harvesting. We want to show if mucoderm used in tunnel technique to recover miller class I and II recessions defects…
- Trial name
- MUCODERM (NCT03162016)
- Testing
- transplants
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Gingivitis, Periodontitis
A Clinical and Imaging Study to Evaluate a Novel Dentifrice
There is a need for toothpastes that more effectively remove oral biofilm, inhibit biofilm re-formation and support periodontal health.
- Conditions
- Gingivitis, Periodontitis, Dental Plaque
- Trial name
- NCT02271815
- Testing
- Oral Hygiene
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- University of California, Irvine
Gingival Recession, Generalized
Comparison Between Connective Graft and Xenogeneic Matrix, in Patients With Multiple Gingival Recessions
Subepithelial connective tissue graft (SCTG) is considered the gold standard for root coverage treatment. However, it is associated with postoperative morbidity, limited amount of donor tissue, and longer surgical time.
- Trial name
- NCT03207984
- Testing
- Root coverage surgery
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Periodontitis
Impact of Non-surgical Periodontal Treatment of miRNome
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with…
- Trial name
- NCT06382935
- Testing
- Probin Pocket Depth reduction
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Catania
Periodontal Diseases
Pinhole Surgical Technique Compared to Connective Tissue Graft in Treatment of Gingival Recession
This study compares the efficacy of root coverage achieved by the Pinhole Surgical Technique (PST) technique and the Connective Tissue Graft (CTG) technique in the treatment of Miller class I and II gingival recession defects.
- Trial name
- NCT04356391
- Testing
- Connective Tissue Graft Technique, Pinhole Surgical Technique
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- State University of New York at Buffalo
Dental Plaque, Gingivitis
Preliminary Evidence of the Efficacy of a Mouthwash Containing 5% Propolis for the Control of Plaque and Gingivitis
Mouthwash based on medicinal plants and propolis can be easily found in the Brazilian market even if it has not been tested in reliable clinical trials on its efficacy or possible unpleasant side effects like the ones which alter…
- Trial name
- MGP (NCT01142843)
- Testing
- green propolis mouthwash
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Federal University of Minas Gerais
Mouth and Tooth Diseases, Periodontal Diseases
Chlorhexidine and Essential Oil Mouthwashes on Human Beta-Defensin 2 (hbD2) and Kathelicidin (LL-37) Saliva Levels
Recent studies have shown that while mouthwashes exhibit antimicrobial properties against bacteria and their products, at the same time showing the cytotoxic effect on living cells in the mouth.29 To the best of our knowledge…
- Conditions
- Mouth and Tooth Diseases, Periodontal Diseases, Gingivitis
- Trial name
- hbD2 (NCT04946617)
- Testing
- undefined
- Volunteers
- 120 people
- Sponsor
- Istanbul Medeniyet University
Periodontitis, Gingivitis
Evaluation of the Effect of Smoking on Pyroptosis in Periodontal Pathogenesis
This study investigates the impact of smoking on pyroptosis and inflammatory signaling pathways in systemically healthy individuals with various periodontal conditions.
- Conditions
- Periodontitis, Gingivitis, Periodontal Diseases, Smoking ( Cigarette)
- Trial name
- NCT07563192
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Plaque, Gingivitis
A Pilot Study to Evaluate a Molecular Method for Plaque
This study is to evaluate the sensitivity of the molecular method and its ability to split a stannous fluoride toothpaste versus a negative control.
- Trial name
- NCT02574221
- Testing
- stannous fluoride toothpaste, cavity protection toothpaste
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dental Plaque, Gingivitis
Mechanical Plaque Control and Gingivitis Reduction in Fixed Appliance Patients
The purpose of this study is to determine whether the use of a sonic toothbrush alone is more effective than two other toothbrushing protocols on dental plaque elimination in patients with fixed orthodontic appliances.
- Trial name
- NCT00681135
- Testing
- sonic toothbrush (Philips Sonicare® FlexCare, Typ HX6942/04), manual toothbrush / interdental toothbrush (elmex® Inter X medium toothbrush / interdental brush Curaprox®), manual toothbrush (elmex® Inter X medium toothbrush)
- Where
- Germany
- Volunteers
- 118 people
- Sponsor
- Sebastian Zingler
Gingival Enlargement
Comparative Evaluation of Hyaluronic Acid Spray and Low-Level Laser Therapy on Wound Healing Following Gingivectomy
Gingival enlargement may impair oral hygiene, esthetics, and periodontal health, and gingivectomy is commonly performed when non-surgical treatment is insufficient.
- Trial name
- NCT07034625
- Testing
- Low Level Laser Therapy, Hyaluronic Acid Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Gingival Recession, Lack of Keratinized Gingiva (Disorder)
Progenitor Potential of Mesenchymal Stem Cells in Palatal Tissue Harvested From Molar and Premolar Sites
The primary purpose of this protocol is to isolate, investigate and compare the regenerative and differentiation potential of mesenchymal stem cells (MSC's) in the gingival (gum) tissue harvested from two different locations from…
- Trial name
- NCT03570333
- Testing
- progenitor potential of Gingival Mesenchymal cells
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Iron-deficiency
The Effect of Different Prebiotics on Iron Absorption From High Dose Iron Supplements
Iron deficiency (ID) remains the most common global nutrient deficiency, with young women at high risk. Iron supplements are first line treatment for ID but absorption is often low.
- Trial name
- NCT04194255
- Testing
- ferrous fumarate, ferrous fumarate + 15 g GOS, ferrous fumarate + 15 g FOS
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Swiss Federal Institute of Technology
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.