Clinical trials: Gingiva Disorder
Graft Pain, Gingival Recession
MEBO Ointment and Hyaluronic Acid Gel in the Management of Pain After Free Gingival Graft Harvesting
Postoperative pain as well as bleeding are the most common complications after palatal graft harvesting also postsurgical swelling have been reported , Although different agents were used to protect the denuded areas on the…
- Trial name
- NCT03728244
- Testing
- MEBO ointment, Hyaluronic Acid gel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingivitis
Evaluate Inflammation Caused by Gingivitis in Adults
The purpose of this study is to compare the anti-inflammatory efficacy of a dentifrice
- Trial name
- NCT00941668
- Testing
- Triclosan/Copolymer/fluoride toothpaste, sodium monofluorophosphate toothpaste
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Thickening; Gingival
Assessment of Keratinized Gingiva With and Without PRF Application in Patients With Dental Implant
we used prf with dental implant treatment to find out whether prf has an effect on increasing the soft tissue thickness and keratinized tissue width
- Trial name
- NCT04864197
- Testing
- platelet rich fibrin
- Where
- Iraq
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Periodontal Diseases, Smoking
The Effect of Scaling and Root Planing on Oral Inflammatory Biomarkers Among E-cig Users and Non-smokers
Background/Aim: There are no studies that have compared the gingival crevicular fluid (GCF) levels of IL-1β in non-smokers (NS) and electronic nicotine delivery system (ENDS)-users before and after scaling and root planing (SRP)…
- Trial name
- ENDS-SRP (NCT05745324)
- Testing
- Scaling and root planing
- Where
- Kuwait
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Atrophy of Gingiva
Volumetric Evaluation of Gingival Augmentation Around Dental Implants
The goal of this observational prospective study is to objectively assess the dimensional (volume \& linear variance) and clinical changes of vestibular gingival soft tissues upon treatment with laser-aided pouch roll…
- Trial name
- NCT06057363
- Testing
- volumetric evaluation of gingival augmentation around dental implants
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Odontostomatologic Laser Therapy Center, Florence, Italy
Genitourinary Syndrome of Menopause, Pelvic Floor Dysfunction
Efficacy and Safety of the Neodymium Laser in Treatment of Urogenital Tract Diseases in Women
Study objective: To evaluate the efficacy and safety of the Magic Max neodymium laser in the medical treatment of women with symptoms of genitourinary syndrome of menopausal, vulvar lichen sclerosus and pelvic floor muscle…
- Conditions
- Genitourinary Syndrome of Menopause, Pelvic Floor Dysfunction, Vulvar Lichen Sclerosus
- Trial name
- NCT05251220
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- 1st Federal Budgetary Healthcare Institution Volga District Medical Center
Gingival Recession
Manual Versus Oscillating-rotating Toothbrushes After Root Coverage Procedure
The aim of this study is to evaluate the gingival margin stability with the use of oscillating-rotating toothbrushes compared to manual toothbrushes.
- Trial name
- NCT02534220
- Testing
- Manual Toothbrush, Oscillating-rotating toothbrush
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Milan
Gingival Recession, Periodontal Atrophy
Comparison Between Two Coronally Positioned Flap With Connective Tissue
The aim of this study is to evaluate the effectiveness of total root coverage between two coronally positioned flap technique in Miller recession Class I and II, in patients attending at "Universidad El Bosque" dental school…
- Trial name
- NCT01814592
- Testing
- coronally partial thickness flap plus connective tissue, coronally mucosal thickness flap
- Where
- Colombia
- Volunteers
- 72 people
- Sponsor
- Universidad El Bosque, Bogotá
HNSCC, HNSCC,Larynx, Pharynx and Oral Cavity
Window Trial of Fluorescently Labeled Panitumumab (Panitumumab-IRDye800) in Head and Neck Cancer
This study is exploring the use of Panitumumab in Head and Neck Cancer. Panitumumab is an approved drug named Vectibix and is used as an anti-cancer agent in other cancers such as colorectal cancer.
- Conditions
- HNSCC, HNSCC,Larynx, Pharynx and Oral Cavity, SCC - Squamous Cell Carcinoma
- Trial name
- NCT06819228
- Testing
- Panitumumab IRDye 800
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Orthodontics, Dental Hygiene
Evaluation of the Effect of a Probiotic in Patients Undergoing Orthodontic Therapy
Orthodontic patients need supplementary oral hygiene tools in addition to professional oral hygiene. The aim of this study is to evaluate the effects of Bifidobacterium animalis subs.
- Conditions
- Orthodontics, Dental Hygiene, Gingivitis and Periodontal Diseases
- Trial name
- NCT06752330
- Testing
- Use of probiotics during oral hygiene at home
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Turin, Italy
Dental Calculus, Gingivitis and Periodontal Diseases
Bio-Descaling Toothpaste for Dental Calculus Reduction
Dental calculus is a calcified mineralized plaque composed primarily of calcium phosphate salts covered by an unmineralized bacterial biofilm layer.
- Conditions
- Dental Calculus, Gingivitis and Periodontal Diseases, Periodontal Diseases
- Trial name
- AntiCal (NCT07689071)
- Testing
- Bio-Descaling Powder (BDP) Toothpaste
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Gingivitis; Chronic
The Effect of Probiotics on Gingivitis
The aim of the study is to assess the effect of oral probiotics containing Streptococcus salivarius M18 on gingivitis and oral hygiene in young adults.
- Trial name
- NCT05727436
- Testing
- Dentoblis
- Where
- Russia
- Volunteers
- 61 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Halitosis, Mouth Disease
Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyrymonas Gingivalis.
The aim of the study: To assess the efficacy of antioxidant (resveratrol) mouthwash in reducing the level of p. gingivitis and oral malodor over 7 day period among undergraduate dental student patients from Mustansiriyah…
- Conditions
- Halitosis, Mouth Disease, Plaque Induced Gingival Disease, Bleeding Gum
- Trial name
- NCT06882564
- Testing
- resveratrol mouthwash, Chlorhexidine mouthwash (0.2%)
- Where
- Iraq
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Periodontitis
Effects of Azithromycin as an Adjunct to Scaling and Root Planning in the Treatment of Periodontitis
The growing interest in the possibilities of modulating macrophages in inflammatory diseases with therapeutic purpose has prompted the development of new approaches for the treatment of periodontitis.
- Trial name
- NCT05506371
- Testing
- Az+SRP, SRP, No interventions
- Where
- Ukraine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ukrainian Medical Stomatological Academy
Gingivitis
Dose-dependent Anti-inflammatory Effects of Vitamin D in a Human Gingivitis Model
The burden of chronic gingivitis and periodontitis in the US is disproportionately high among Non-Hispanic Blacks compared to Non-Hispanic Whites.
- Trial name
- NCT00779909
- Testing
- vitamin D3
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Boston University
Gingival Recession
Xenogenous Collagen Matrix Graft With or Without Enamel Matrix Proteins Derivative for Root Coverage
The purpose of this study is to evaluate the reduction of gingival recession of single Miller Class I and II defects treated by coronally advanced flap with subepithelial porcine collagen matrix graft and / or enamel matrix…
- Trial name
- NCT02456337
- Testing
- Mucograft, Emdogain, Coronally Advanced flap
- Where
- Brazil
- Volunteers
- 49 people
- Sponsor
- University of Campinas, Brazil
Tooth Decay, Cavities of Teeth
Plaque Removal Effectiveness of a Flossing Device Compared to the Conventional Flossing in Adults
Objective: To evaluate the effectiveness in plaque removal of the new device; Dental floss holders and compare the results to the conventional way of flossing.
- Conditions
- Tooth Decay, Cavities of Teeth, Gingivitis, Plaque
- Trial name
- NCT06318819
- Testing
- Dental Floss Holders
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maha A. Bahammam
Obesity, Periodontitis
Gingival Crevicular Fluid Vaspin and Omentin Levels in Obese Patients With Chronic Periodontitis
Our objective in this case-control intervention study, therefore, was to explore the effect of nonsurgical periodontal therapy on the GCF levels of vaspin and omentin in patients with chronic periodontitis in order to determine…
- Trial name
- NCT02563171
- Testing
- non surgical periodontal treatment, Gingival crevicular fluid collection
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Umut BALLI
Periodontis, Aggressive Periodontitis
Single-cell and Spatial Transcriptomic Profiling of Gingival Tissues in Aggressive and Chronic Periodontitis: Deciphering Cellular Heterogeneity and Inflammatory Microenvironment Features
The goal of this observational study is to investigate cellular heterogeneity and inflammatory microenvironment features in gingival tissues from patients with aggressive periodontitis compared to chronic periodontitis and…
- Trial name
- NCT07487272
- Where
- China
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Oral Leukoplakia, Oral Leukoplakia of Tongue
Prediction of Malignant Transformation of Oral Leukoplakia Using a MAGE-A-based Immunoscore
Oral squamous cell carcinomas (OSCC) is among the most common malignancies worldwide. Early detection and prevention of OSCC is thought to have the highest potential to reduce morbidity and mortality.
- Conditions
- Oral Leukoplakia, Oral Leukoplakia of Tongue, Oral Leukoplakia of Gingiva, Oral Lichen Planus
- Trial name
- PREDICT-OLP (NCT03975322)
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
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