Clinical trials: Gingiva Disorder
Gingival Recession
Partial-thickness/Non-advanced vs. Full-thickness/MCAT Tunnelling for the Treatment of Multiple Gingival Recessions
Included patients will be randomly allocated to the test (split-thickness non-advanced tunnel - Zabalegui et al. 1999) or to the control group (full-thickness coronally-advanced tunnel - MCAT - Aroca et al. 2010).
- Trial name
- Tun_RCT (NCT05655247)
- Testing
- Split-thickness non-advanced tunnel (Zabalegui et al. 1999), Full-thickness coronally-advanced tunnel (Aroca et al. 2010)
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Universidad Complutense de Madrid
Periodontal Pocket
The Proposed Study Aims to Investigate the Impact of Adjunctive Vitamin D Gel Application on Gingival Crevicular Fluid Levels of Alkaline Phosphatase and Interleukin-8 in Periodontitis Patients Undergoing Phase 1 Periodontal Therapy. By Elucidating the Molecular Mechanisms Underlying the Therapeutic
The proposed study aims to investigate the impact of adjunctive vitamin D gel application on gingival crevicular fluid levels of alkaline phosphatase and interleukin-8 in periodontitis patients undergoing phase 1 periodontal…
- Trial name
- NCT06669026
- Testing
- vitamin D loaded Poly lactic-co-glycolic acid nanoparticles gel, vitamin D3 gel (regular non-nanoparticle form), only mechanical debridement
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Gingival Diseases
Effects of Three Different Mouth Rinses on Dental Plaque in Children
Dental plaque is a major problem in the field of oral and dental health and its prevention is more important to avoid dental caries and gingival diseases.
- Trial name
- NCT06013735
- Testing
- sodium fluoride solution, guava leaves aqueous extract, pomegranate peel aqueous extrac
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Suez Canal University
Periodontal Diseases, Periodontitis
Assessment of Salivary GM-CSF, MIP, and IL-1β Levels in Subjects With Varying Periodontal Conditions
In order to determine the pathogenesis of chronic inflammatory diseases, the levels of various cytokines are examined in tissues and fluids taken from the body.
- Conditions
- Periodontal Diseases, Periodontitis, Gingivitis, Periodontal Health
- Trial name
- NCT06961409
- Testing
- Saliva obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Orthodontic, Gingival Recession
The Impact of a 3D Imaging Tool on Reducing Gum Recession During Orthodontic Treatment With Aligners
This study investigates whether using 3D imaging technology (Cone Beam Computed Tomography or CBCT) for orthodontic treatment planning with aligners can reduce the risk of gingival recession in adult patients seeking dental arch…
- Conditions
- Orthodontic, Gingival Recession, Cone-Beam Computed Tomography
- Trial name
- GOPRO (NCT07513792)
- Testing
- 3D CBCT-Guided Orthodontic Treatment with Aligners, conventional orthodontic treatment planning
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University of Liege
Gingivitis
Anti-Inflammatory Efficacy of Ginger Containing Dentifrice in the Control of Biofilm Induced Gingivitis
The goal of this clinical trial is to test efficiency of using toothpaste containing (Ginger) over a period of three month to control on gingival inflammation and plaque accumulation through measuring the clinical periodontal…
- Trial name
- NCT05868200
- Testing
- Capitano zenzero toothpaste, Colgate total toothpaste
- Where
- Iraq
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Periodontal Diseases
The Effect of Non-Surgical Periodontal Treatment on Bone Metabolism in Type 2 Diabetes and Systemically Healthy Individuals
In this study, it was concluded that sclerostin and irisin may be alternative markers for evaluating the effectiveness of periodontal treatment and healing of periodontal tissues by affecting bone metabolism.
- Trial name
- NCT05862311
- Testing
- ELISA
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Gingival Inflammation
Investigation of the Interplay Between Local Oral Inflammation, Microbiota and Systemic Immune Responses.
This is a clinical research study designed to measure changes in inflammation and the oral microbiome during a phase of good oral hygiene and the absence of oral hygiene.
- Trial name
- ILIMSIR (NCT06966492)
- Testing
- Stannous Fluoride Toothpaste (SnF)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingival Recession, Tooth Abrasion
A New Surgical-restorative Approach to Treat Gingival Recessions Associated With Non-carious Cervical Lesions (NCCL)
The aim of the present study is to evaluate the clinical, aesthetic and patient-centered parameters of connective tissue graft associated or not with partial resin composite (RC) for the treatment of gingival recession with NCCL…
- Trial name
- NCT02817763
- Testing
- Connective tissue graft (CTG), CTG plus resin composite restoration, sodium dipyrone
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Gingival Recession
A Modified Tunnel Approach in Treatment of Gingival Recession
Objectives: To clinically evaluate the healing of Miller Class I and II isolated gingival recessions treated with the modified tunnel approach (mTA) versus the conventional tunnel technique (cTT) in conjunction with subepithelial…
- Trial name
- NCT02642887
- Testing
- mTA + SCTG
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Gingivitis, Gingival Diseases
NOVOSYN® Quick Versus MONOSYN® Quick Suture Material in Resective Periodontal Surgery
The aim of this study is to prove that Novosyn Quick and Monosyn Quick are equivalent in early wound healing in adult patients undergoing resective periodontal surgery.
- Conditions
- Gingivitis, Gingival Diseases, Periodontal Diseases
- Trial name
- NOQMOQS (NCT05813236)
- Testing
- Novosyn® in resective periodontal surgery, Monosyn® in resective periodontal surgery
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Aesculap AG
Gingival Recession
Microsurgical Versus Conventional Semilunar Coronally Advanced Flap
BACKGROUND: The semilunar coronally repositioned flap (SLCRF) has been used for the treatment of recession defects (GR). Recently a microsusgical (MICRO) has been successfully employed with the procedure apparently resulting in…
- Trial name
- NCT02433899
- Testing
- MICROSURGERY, MACROSURGERY, Dexamethasone
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Cognitive Performance, Sleep Quality
The Effect of Caffeinated Chewing Gum on Cognitive Performance in Night-shift Emergency Physicians
This study aimed to examine the impact of caffeinated chewing gum on the cognitive performance of night-shift emergency physicians in a partially sleep-deprived state.
- Trial name
- NCT06693505
- Testing
- caffeinated chewing gum
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Gingival Recession, Gingival Diseases
Influence of Anatomical Factors Upon Root Coverage
Introduction: Gingival recession is a lesion characterized by the loss of attachment of root surface of the tooth, resulting in an apical migration of the gingival margin that occasionally generates aesthetic problems…
- Conditions
- Gingival Recession, Gingival Diseases, Periodontal Attachment Loss
- Trial name
- NCT04813302
- Testing
- Coronally advanced flap and connective tissue graft
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Gingival Recession, Localized
Ultrasonographic Evaluation of the Connective Tissue Grafts Obtained With Two Different Methods in Root Coverage
Gingival recession is a clinical problem that increases with age and affects patient comfort. It is defined as the displacement of the gingival margin to a more apical position of the cementum-enamel border of the tooth.
- Trial name
- NCT06373783
- Testing
- subepithelial connective tissue graft, de- epithelize gingival graft, ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Gingival Recession
Root Coverage Comparing an Allograft to a Bovine Xenograft
Root coverage with acellular dermal matrix using the coronally positioned tunnel technique comparing two different donor materials
- Trial name
- NCT02810067
- Testing
- Tunnel + AlloDerm, Tunnel + Novomatrix
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Louisville
Gingivitis
The Effects of Green Tea and Salvadora Persica L. in Patients With Gingivitis
Gingivitis is an inflammatory condition of the gingival tissue, most commonly caused by bacterial infection.The plaque control is considered the most important preventive factor concerning caries, gingivitis, and periodontitis…
- Trial name
- NCT06211309
- Testing
- co.mouthwas, Kin, Distilled water
- Where
- Iraq
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Periodontitis, Periodontal Diseases
Effect of Smoking and Periodontal Therapy on Salivary and Gingival Crevicular IL-17 and IL-35
Periodontal diseases are among the major causes of tooth loss. Smoking may play a role as a contributing factor in the development of periodontitis by reducing the immune response.
- Conditions
- Periodontitis, Periodontal Diseases, Smoking, Smoking, Tobacco
- Trial name
- NCT05281848
- Testing
- Non-surgical periodontal treatment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Gazi University
Gingival Recession
Amnion Membrane Versus DFGG Using the Tunneling Technique in Management of Gingival Recession Defects.
Treatment of gingival recession is indicated mainly for esthetic reasons and keratinized tissue augmentation (Zucchelli and Mounssif, 2015).
- Trial name
- NCT06146855
- Testing
- Tunneling procedure with Amnion Membrane, Tunneling procedure with De-epithelialized Free Gingival Graft
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Periodontal Diseases
Gingival Crevicular Fluid Levels of Prolactin Hormone in Obese Patients With Stage ii and Iii Periodontitis Before and After Non-surgical Periodontal Therapy
Obesity and periodontitis are among the most common chronic disorders affecting the world population, while Prolactin (PRL) is a neuroendocrine hormone that within the physiological range stimulates bone formation while mild to…
- Trial name
- NCT07571850
- Testing
- Obese patients with stage II and III periodontitis and non surgical peridontal therapy, obese patients with healthy periodontium with no intervention
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University
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