Clinical trials: Gingiva Disorder
Gingivitis, Cardiovascular Diseases
Dietary Nitrate Functional Gum Effect on Gingivitis and Heart Health
The purpose of this research is to determine the effects of a chewing gum containing dietary nitrate to gingival and heart health. Dietary nitrates are commonly found in leafy vegetables and beets.
- Conditions
- Gingivitis, Cardiovascular Diseases, Gingival Diseases, Gingival Bleeding
- Trial name
- NCT06029283
- Testing
- dietary nitrate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Maryland, Baltimore
Periodontal Disease
Endocan, VEGF and TNF-alpha Levels in Periodontal Disease and After Treatment
The primer aim of the study was to determine serum and gingival crevicular fluid (GCF) endocan levels in periodontal diseases pathogenesis supported with vascular endothelial growth factor (VEGF) and tumor necrosis factor alpha…
- Trial name
- NCT02750956
- Testing
- Non-surgical periodontal treatment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Positive Regulation of Oxidative Stress Process
A Clinical Trial to Study the Effect of Lycopene in Patients With Gum Disease and type2 Diabetes Mellitus
This study was performed to assess the efficacy of systemic lycopene (8 mgms Daily for two months) as an adjunct to scaling and root planing in chronic periodontitis patients with type 2 diabetes mellitus.
- Trial name
- "SLSRPD" (NCT02263352)
- Testing
- Lycored soft gels Jagsonpal Pharma, Systemic 8mgms/day, Scaling and root planing
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Gingivitis, Maxillary Transversal Deficiency
St. John's Wort Oil Versus Chlorhexidine Mouthwash for Gingival Problems After Rapid Maxillary Expansion
The goal of this clinical trial was to learn whether St. John's wort (Hypericum perforatum) oil helps gum healing in children and adolescents aged 11 to 16 years after treatment with a rapid maxillary expansion appliance.
- Trial name
- SJW-CHX-RME (NCT07882771)
- Testing
- St. John's Wort Oil, Chlorhexidine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Gingival Recession
Evaluation of SECTG Vs. Laser-DGG in Management of Gingival Recessions.
This study evaluates laser de-epithelialized gingival graft to be as effective as subepithelial connective tissue graft in management of multiple gingival recessions using tunneling technique.
- Trial name
- NCT04133298
- Testing
- Tunneling with laser de-epithelized gingival graft, Tunnelingwith subepithelial connective tissue graf
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingivitis, Plaque, Dental
Clinical Investigation Examining Plaque and Gingivitis Connected Toothbrush Compared to Non-Connected Toothbrush
The objective of this clinical research study is to assess plaque and gingivitis reductions of Connected Toothbrush compared to Non-Connected Toothbrush over a six-week clinical study.
- Trial name
- Connected (NCT04221334)
- Testing
- Electric Toothbrush, oral health care application
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
COVID 19
Potential Role of Gum Arabic as Immunomodulatory Agent Among COVID 19 Patients
To study the efficacy of Gum Arabic as an immuno modulator and anti-inflammatory agent among COVID 19 seropositive patients..Half of participants will receive Gum Arabic and the other half will receive placebo
- Trial name
- GA&COVID19 (NCT04381871)
- Testing
- Acacia Senegal, Pectin
- Where
- 2 sites in Sudan
- Volunteers
- 110 people
- Sponsor
- Al-Neelain University
Periodontal Diseases
Osteocalcin Level in Gingival Clavicular Fluid During Canine Retraction in Periodontal Compromised Patients
Osteocalcin levels can be measured Gingival crevicular fluid (GCF). Changes in osteocalcin levels can provide important information about the status of bone metabolism and bone remodeling.
- Trial name
- NCT06102616
- Testing
- measure Osteocalcin level
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Faculty of Dental Medicine for Girls
Down Syndrome, Gingival Bleeding
Clinical Comparison of a Postbiotic-gel With Placebo Gel for Gingival Inflammation in Patients With Down Syndrome
The aim of the study is to evaluate the efficacy of home treatment with a postbiotic-based gel for the management of periodontal inflammation in patients with Down syndrome. Patients will be enrolled at the S.C.
- Trial name
- NCT06293911
- Testing
- Biorepair Plus Parodontgel Intensive
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Graft Shrinkage, Gingival Recession, Localized
Effect of i-PRF and LLLT on Free Gingival Graft Shrinkage
This randomized clinical trial aims to evaluate whether injectable platelet-rich fibrin (i-PRF) and low-level laser therapy (LLLT) can reduce graft shrinkage after free gingival graft procedures.
- Trial name
- NCT07303192
- Testing
- Free Gingival Graft (FGG), Injectable Platelet-Rich Fibrin (i-PRF), Low-Level Laser Therapy (LLLT)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Tobacco Use, Periodontitis
Snuff Use, Smoking, Periodontal Health and Premature Death: 30-year Study
Snuff use and smoking associated with poor periodontal health, especially if used together.
- Trial name
- NCT03614871
- Testing
- Epidemiological study
- Volunteers
- 1,676 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Obesity, Periodontitis
The Role of Visfatin in Obesity and Periodontal Disease
Visfatin is an adipokine that plays an important role in immune functions as a growth factor, enzyme, and proinflammatory mediator.
- Trial name
- NCT03470987
- Testing
- Phase I Periodontal therapy, Metabolic control
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gazi University
Gingival Recession, Palate; Wound
Ultrasonographic Assessment of Palatal Wound Healing
Palatal-tissue harvesting is a routinely performed procedure in periodontal plastic surgery. Subepithelial connective tissue graft (sCTG) is considered the gold standard in root coverage.
- Trial name
- NCT06118177
- Testing
- connective tissue harvesting, ultrasonography, autolog platelet rich fibrin application
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Dental Plaque, Gingivitis
Effectiveness of Toothbrushing Habits of Preschool Children, With or Without a Toothbrushing Assisting Application
The aim of this study is to investigate the effectiveness of the use of a toothbrushing assisting mobile application in dental plaque removal and adherence to the toothbrushing routine, in preschool children (3-5 yrs old) when…
- Trial name
- NCT05788692
- Testing
- electric tootbrush, manual toothbrush, toothbrushing assisting application
- Where
- 6 sites in Greece
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Gingivitis
Treatment of Human Gingivitis With Amnion-derived Cellular Cytokine Solution (ACCS)
The purpose of this study is to evaluate the safety of oral topical application of Amnion-derived Cellular Cytokine Solution (ACCS) in subjects with gingivitis
- Trial name
- NCT02071199
- Testing
- 1X ACCS (Amnion-derived Cellular Cytokine Solution), Normal saline, 0.3X ACCS
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Noveome Biotherapeutics, formerly Stemnion
Gingival Recession, Localized
Er,Cr:YSGG Laser For Recipient Bed Bio-modification And Connective Tissue Harvesting in Treatment of Gingival Recession
A clinical and radiographic evaluation of using Erbium, Chromium, Scandium, Gallium and Garnet (Er,Cr:YSGG) laser in recipient site bio-modification and de-epithelialized connective tissue graft harvesting compared to…
- Trial name
- NCT03200392
- Testing
- laser root surface conditioning & laser DGG harvesting, laser root surface conditioning & blade DGG harvesting, blade DGG harvesting
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Misr International University
Periodontal Diseases
Evaluation of GCF And Salivary Ferritin, ALP And MMP-8 Levels of Individuals With Different Periodontal Diseases
The aim of this clinical study was to determine the levels of ferritin, alkaline phosphatase and matrix metalloproteinase-8 in the gingival crevicular fluid (GCF) and saliva samples were collected from 60 systemically healthy…
- Trial name
- NCT06561802
- Testing
- GCF and saliva obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Gingivitis
Dose Finding Study to Assess Octenidine Mouthwash Concentrations in Comparison to Placebo
The objective of this clinical trial is to identify the most efficacious octenidine dihydrochloride concentration regarding bacterial count reduction in comparison to a placebo in the oral cavity.
- Trial name
- OML0113 (NCT02138552)
- Testing
- Octenidine dihydrochloride
- Where
- 2 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Schülke & Mayr GmbH
Dental Caries, Gingival Inflammation
DETERMINATION OF THE EFFECTS OF STAINLESS STEEL CROWNS CEMENTED WITH RESIN CEMENTS ON INTERLEUKIN-10, 12, 18 LEVELS IN GINGIVAL CREVICULAR FLUID
This split-mouth clinical study aimed to evaluate the early effects of stainless steel crowns cemented with self-adhesive resin cement and high-viscosity glass ionomer cement on clinical periodontal parameters and interleukin-10…
- Conditions
- Dental Caries, Gingival Inflammation, Periodontal Response to Dental Restorative Materials
- Trial name
- SSC-CYTO (NCT07421206)
- Testing
- Self-Adhesive Resin Cement Group, High-Viscosity Glass Ionomer Cement
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Gingival Recession
Platelet Rich Fibrin on Root Coverage of Gingival Recessions
Several surgical techniques and various adjunctive agents have been used to covered Gingival Recession (GR) and promote clinical outcomes.
- Trial name
- NCT04248049
- Testing
- Platelet rich fibrin
- Where
- Colombia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universidad Antonio Nariño
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