Clinical trials: Gingiva Disorder
Gingivitis
Dietary Collagen Peptides and Periodontal Inflammation
This randomized, double-blind, placebo-controlled 2-arm, parallel group clinical trial is designed to evaluate the impact of the regular consumption of collagen peptides on the clinical signs of gingival and periodontal…
- Trial name
- NCT03765125
- Testing
- collagen peptide test
- Where
- 2 sites in Germany
- Volunteers
- 40 people
- Sponsor
- Wuerzburg University Hospital
Gingival Recession
A Comparision of Collagen Matrix and Connective Tissue Graft With Modified Coronally Advanced Tunnel for Root Coverage
Recently porcine derived bioresorbable collagen matrices have shown predictable outcomes for augmenting keratinzed gingiva , improved wound healing, recession coverage in localized gingival recessions and multiple recession…
- Trial name
- NCT02876562
- Testing
- root coverage with collagen matrix
- Where
- India
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Polycystic Ovary Syndrome, Inflammation Gum
Endocan Levels at Polycystic Ovary Syndrome and Periodontal Inflammation
Periodontal diseases are chronic inflammatory disease occurred by the interaction between pathogenic microorganism and the host defense.
- Conditions
- Polycystic Ovary Syndrome, Inflammation Gum, Cytokines
- Trial name
- NCT03264846
- Testing
- Collection of Serum and Saliva Samples
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Ebru Saglam
Spondylosis, Spondylolisthesis
Return of Bowel Function After One or Two Level Anterior Lumbar Interbody Fusion With Chewing Gum
Researchers are trying to identify is chewing gum improves bowel function after anterior lumbar interbody fusion
- Conditions
- Spondylosis, Spondylolisthesis, Neurogenic Claudication, Foraminal Stenosis
- Trial name
- NCT03945461
- Testing
- Chewing gum
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Periodontal Pocket, Periodontitis
Treatment Of Shallow Periodontal Pockets 4-6mm Using AIRFLOW Prophylaxis Master Device With Erythritol vs Manual Scalers
Periodontitis is a chronic condition associated with the inflammatory destruction of the periodontal tissues ultimately leading to tooth loss.
- Conditions
- Periodontal Pocket, Periodontitis, Gingival Diseases, Gingival Bleeding
- Trial name
- NCT06351982
- Testing
- Electro Medical Systems AIRFLOW® Prophylaxis Master Device, Hand and ultrasonic scalers and curettes
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingivitis
A Study is to Evaluate a Regimen on Gingivitis Using Traditional and Novel Assessment Methods
Subjects who have shown evidence of gingivitis and plaque will be enrolled in this study. Each subject will be randomly assigned to one of two treatment products.
- Trial name
- NCT07211061
- Testing
- Stannous Fluoride Dentifrice, Sodium Fluoride Dentifrice, electric toothbrush
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Gingival Recession, Localized
Theravex Oral and Theravex Tissue Care Plus in the Healing Process of Mucogingival Surgery
This clinical study assesses the efficacy of two novel bioactive solutions, Theravex Oral and Theravex Tissue Care Plus, in enhancing soft tissue healing after periodontal surgery.
- Trial name
- NCT07430670
- Testing
- Modified Free Gingival Graft (M-FGG), Theravex Bioactive Solutions (Tissue Care Plus and Oral)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Gingival Recession, Localized
Effectiveness of Modified-free Gingival Graft for Treatment of Localized Gingival Recession Defects
The aim of the present study is to evaluate, whether use of the modified free gingival graft (mod-FGG) technique improves treatment outcomes after surgical root coverage at mandibular incisors with gingival recession defects.
- Trial name
- NCT04718545
- Testing
- Mucogingival surgery
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Göteborg University
Gingival Recession
Comparative Evaluation of CTG With and Without rhPDGF- BB Using Modified Coronally Advanced Tunnel for Root Coverage
The present study is a human, prospective, single centre, single blind, comparative controlled randomized clinical trial for the treatment of Miller's Class I, II or combination of class I and II mandibular recession and…
- Trial name
- NCT03676088
- Testing
- root coverage
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Chronic Periodontitis, Generalized, Gingivitis
Measurement of Oncostatin M, Leukemia Inhibitory Factor and Interleukin-11 Levels of Patients With Periodontal Disease
This study aims to determine Oncostatin M (OSM), Leukemia inhibitory factor (LIF), and Interleukin-11 (IL-11) levels in gingival crevicular fluid (GCF), saliva, and serum in periodontally healthy individuals and those with…
- Trial name
- NCT04597073
- Testing
- Initial Periodontal Therapy
- Volunteers
- 72 people
- Sponsor
- Ataturk University
Cardiac Arrest, Inflammation
Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)
This is a prospective, observational study to investigate molecular mechanisms mediating the systemic inflammatory process, and changes to metabolism, and their impact on brain injury, survival, and functional outcomes after…
- Conditions
- Cardiac Arrest, Inflammation, Obesity, Hypoxic Ischemic Encephalopathy (HIE)
- Trial name
- PCAS (NCT02664831)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- MaineHealth
Tooth Discolouration
16% Carbamide Peroxide Home Bleaching: Soft vs. Rigid Tray in a Randomized Blinded Equivalence Trial
The aim of this clinical study is to evaluate patient satisfaction, bleaching efficacy, and the risk and severity of tooth sensitivity and gingival irritation during home bleaching with 16% carbamide peroxide using conventional…
- Trial name
- Rigid tray (NCT06881654)
- Testing
- Bleaching teeth
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Rey Juan Carlos
Periodontal Diseases, Chronic Periodontitis
Effect of Switching From Cigarette Smoking to the Use of IQOS on Periodontitis Treatment Outcome
The purpose of this study was to demonstrate in patients with generalized chronic periodontitis that switching from cigarette smoking to using IQOS improves the response to periodontal therapy and the overall oral health status…
- Conditions
- Periodontal Diseases, Chronic Periodontitis, Periodontal Pocket, Tooth Mobility
- Trial name
- NCT03364751
- Testing
- IQOS, Cigarette
- Where
- 26 sites in Japan
- Volunteers
- 179 people
- Sponsor
- Philip Morris Products S.A.
Periodontitis, Subgingival Plaque
The Effect of Post-surgical Chlorhexidine Mouth Washing on the Sub-gingival Periodontal Microbiome A Pilot Study
Prospective applicants who conform with inclusion and exclusion criteria will be accepted into the study and sign a consent form.
- Trial name
- SUPEM1 (NCT05355740)
- Testing
- Corsodyl
- Where
- 2 sites in Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Gingivitis
Effect of Nigella Sativa Toothpaste on Salivary Biomarkers in Patients With Gingivitis
This study evaluated the effects of Nigella sativa toothpaste on salivary inflammatory biomarkers (IL-1β, PGE2, and MMP-8) in Indonesian Army personnel with gingivitis.
- Trial name
- NS-GINGIVITIS (NCT07447349)
- Testing
- Nigella sativa toothpaste
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Universitas Airlangga
Oral Mucosa
Diagnostic Markers of Neuropathic Odontalgia
The DIAMOND study aims to investigate the presence and diagnostic relevance of potential biomarkers of the blood-nerve barrier disruption as surrogate markers of painful post-traumatic trigeminal neuropathic pain in patients…
- Trial name
- DIAMOND-1 (NCT04142918)
- Testing
- Immunostaining
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gingival Recession, Surgery
Analysis of Root Coverage Stability.
One-hundred and one healthy participants (221 gingival recessions-GRs) were treated from 1987 to 1996. The probing depth (PD), keratinized tissue width (KTW), gingival recession depth (RD), gingival recession width (RW), gingival…
- Conditions
- Gingival Recession, Surgery, Oral Disease
- Trial name
- NCT05439382
- Testing
- Gingival recession regenerative surgery
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Gingival Recession Localized Moderate
Comparing Tunnel Technique and CAF With CTG in Mandibular Gingival Recession Treatment
The goal of this clinical trial is to evaluate the effectiveness of two different surgical techniques, the Coronally Advanced Flap (CAF) and the Tunnel Technique (TT) with Connective Tissue Grafts (CTG), in treating mandibular…
- Trial name
- NCT06135662
- Testing
- CAF + CTG, Tunnel Technique + CTG
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Gingival Recession
Effect of Low-Level Laser on Pain and Healing of Donor Site Following Free Gingival Graft
The aim of this randomized split-mouth design clinical trial is to clinically evaluate the effectiveness of diode laser in the healing of donor site of palate in free gingival graft.
- Trial name
- NCT02896283
- Testing
- Low-level laser therapy, Turned-off laser
- Where
- Iran
- Volunteers
- 12 people
- Sponsor
- Tehran University of Medical Sciences
Gingival Hemorrhage, Gingivitis
Intra-oral Camera in Gingival Health
Evaluate the effects of using an intra-oral camera (IOC) during supportive periodontal therapy (SPT), on the psychological, behavioral and clinical parameters of patients with gingivitis, outlined by evidence and a theory-based…
- Conditions
- Gingival Hemorrhage, Gingivitis, Health Behavior, Communication
- Trial name
- NCT02725983
- Testing
- SPT consultation, SOPROCARE®
- Volunteers
- 78 people
- Sponsor
- University of Lisbon
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