Clinical trials: Gingival Diseases
Gingival Recession
Use of Platelet Rich Fibrin in Addition to CAF and SCTG for Treatment of Gingival Recession
This research will be conducted in an attempt to achieve complete root coverage with physiologic probing depth and a harmonious view with the adjacent tissues using Platelet rich fibrin in conjunction with Coronally advanced flap…
- Trial name
- NCT03199118
- Testing
- CAF +SCTG, platelet rich fibrin
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Plaque
Investigation of Dental Plaque and Gingival Index
Investigation of inhibitory effect of prototype toothpaste on dental plaque formation via modified gingival margin plaque index method.
- Trial name
- NCT00759031
- Testing
- Sodium Monofluorophosphate, Triclosan/Fluoride/Copolymer
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingival Recession, Bone Loss, Alveolar
Esthetic Outcomes of Single Immediate Implant Placement
A randomized controlled trial of 12-month duration to compare gingival margin location, buccal horizontal ridge dimensions, and interproximal crestal bone levels following two surgical approaches for immediate placement of…
- Trial name
- NCT02435706
- Testing
- Flapless immediate implant placement, Flap assisted immediate implant placement, Implant and temporary crown
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Columbia University
Dental Plaque
Efficacy of Plaque Removal of a Novel Brushing Device
The purpose of this research study is to compare how a novel, automated mouthpiece-based toothbrushing device removes dental plaque compared to a manual toothbrush.
- Trial name
- NCT05038293
- Testing
- Automated mouthpiece-based toothbrush, Manual toothbrush
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Washington
Gingivitis
Comparative Efficacy of a Toothpaste That Reduces Plaque and Gingivitis
The objective of this study is to evaluate the performance of two toothpastes in controlling established gingivitis and dental plaque in adults.
- Trial name
- NCT00926328
- Testing
- Triclosan, fluoride, Fluoride
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingival Inflammation
Efficacy of Eco-Friendly Toothpaste Tablets Versus Conventional Toothpaste Using PI and GI Index
Objectives: To assess the change in gingival index (GI) and plaque index (PI) when comparing the use of toothpaste tablets to conventional toothpaste.
- Trial name
- NCT05805865
- Testing
- Toothpaste Tablet, Conventional Toothpaste
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Gingival Recession
Single Stage Root Coverage for Gingival Recession With or Without Free Gingival Graft
Background and Objective: Gingival recession accounts for apical migration of the gingival margin resulting in exposure of the cementoenamel junction (CEJ) and root surface.
- Trial name
- NCT03370042
- Testing
- semilunar coronally positioned flap with free gingival graft, semilunar coronally positioned flap alone
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kamineni Institute of Dental Sciences
Gingivitis
Iranian Traditional Mouth Rinse Punica Granatum Pleniflora (Golnaar) in Treatment of Gingivitis in Diabetic Patients
This is a triple-blinded randomized clinical trial to evaluate the effect of an Iranian traditional mouth rinse (Punica granatum Pleniflora or "Golnaar" mouthrinse) on treatment of diabetic gingivitis and compare it with…
- Trial name
- Golnaar (NCT02227485)
- Testing
- Punica granatum Pleniflora (Golnaar) mouth rinse, Chlorhexidine (0.2%), Tooth bleaching
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Shiraz University of Medical Sciences
Gingivitis
Evaluate Inflammation Caused by Gingivitis in Adults
The purpose of this study is to compare the anti-inflammatory efficacy of a dentifrice
- Trial name
- NCT00941668
- Testing
- Triclosan/Copolymer/fluoride toothpaste, sodium monofluorophosphate toothpaste
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis, Plaque, Dental
Cetylpyridium Chloride (CPC) Based Chewing Gum and Gingivitis
This placebo-controlled, double-blinded, randomized crossover study evaluates the plaque and gingivitis reducing capacity of Cetylpyridium Chloride (CPC) chewing gum, with mechanical oral hygiene.
- Conditions
- Gingivitis, Plaque, Dental, Periodontal Diseases
- Trial name
- NCT03219840
- Testing
- Cetylpyridinium Chloride (CPC) 0.09% + Xylitol chewing gum, Xylitol only chewing gum
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Gingivitis
A Controlled Clinical Study to Determine the Gingivitis Benefit of Flossing
This is a randomized, controlled, examiner-blind, parallel group, four week clinical study comparing brushing plus flossing to brushing alone in 60 healthy adults with pre-existing gingivitis.
- Trial name
- NCT00964860
- Testing
- Glide dental floss
- Where
- Guatemala
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Gingival Diseases
Evaluate Clinical Research From Commerical Oral Care Products
The purpose of this study is to conduct a clinical study comparing anti-plaque efficacy of commercial oral care products.
- Trial name
- NCT00759187
- Testing
- Fluoride, Triclosan/Fluoride, Chlorhexidine Gluconate
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingival Recession
Platelet Rich Fibrin vs Sub Epithelial Connective Tissue and Coronally Advanced Flap Alone in Gingival Recession
Gingival thickness plays a key role not only in the etiology but also in the treatment of gingival recessions. a thin marginal tissue lining the hard periodontal tissues seems to be one of the main risk factor for the onset of…
- Trial name
- NCT03712852
- Testing
- PRF+CAF treated patients, SCTG+ CAF treated patients, CAF treated patients
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Plaque, Dental, Gingivitis
Evaluation of Toothbrush Bristles in Plaque Reduction
The purpose of this cross-over clinical research is to evaluate the cleaning efficacy of toothbrushes tufted with two types of tapered bristles and end rounded bristles in removal of interdental plaque with clinical measurement…
- Trial name
- NCT04681885
- Testing
- Tapered bristles A, Tapered bristles B, End rounded bristles
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sunstar Americas
Dental Caries
Comparing Mouth Rinses (and Chewing Gum) in Regard to Streptococcus Mutans Reduction
This study compared four mouth rinses/chews for their ability to reduce Streptococcus Mutans after usage. The four that were compared were chlorhexidine gluconate (0.12%), sodium fluoride (0.05%), paraffin wax chewing gum (sugar…
- Trial name
- NCT02598778
- Testing
- Chlorhexidine gluconate (0.12%), Sodium Fluoride (0.05%), Paraffin wax chewing gum (sugar-free)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Gingivitis, Plaque
Measuring Efficacy of an Oral-Irrigator After Three Weeks of Use
The primary objective of this exploratory study is to evaluate the efficacy of an Oral Irrigator in the reduction of gingivitis compared to a negative control over a 3 week period by using the Modified Gingival Index and the…
- Trial name
- NCT04899440
- Testing
- Water Flosser, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Periodontitis, Gingivitis
The Effects of DHA on Periodontitis
The purpose of this study is to determine whether docosahexaenoic acid (DHA) is effective in the treatment of periodontitis in adults.
- Conditions
- Periodontitis, Gingivitis, Inflammation
- Trial name
- DAP (NCT01976806)
- Testing
- Aspirin, Docosahexaenoic acid
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Aggressive Periodontitis
Evaluation of Efficacy of Full-mouth Disinfection in Generalized Aggressive Periodontitis Patients
The purpose of this study is to determine whether full-mouth disinfection is effective in the initial periodontal treatment of generalized aggressive periodontitis on clinical parameters, gingival crevicular fluid interleukin-1β…
- Trial name
- NCT02466646
- Testing
- Klorhex® Gel, rinse and spray, Conventional IPT, Full-mouth IPT
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Marmara University
Gingivitis
Potential of Stannous Fluoride Toothpaste to Reduce Gum Disease
This will be a single-center, 12 week, examiner-blind, randomized, stratified (gender and baseline mean whole mouth MGI score), two-treatment, parallel group, clinical study in healthy adult volunteers with moderate gingivitis.
- Trial name
- NCT02750943
- Testing
- Stannous Fluoride, Sodium Monofluorophosphate
- Where
- United States
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Palatal Wound
Comparison of Two Different Low-level Laser Intensity Protocols on the Healing of Palatal Wounds
The aim of this study was to compare two intensities of LLLT on wound healing process of the donor palatine area after CTG removal.
- Trial name
- NCT02580357
- Testing
- Low Level Laser Therapy, GaAlAs laser
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho