Clinical trials: Gingival Graft
Gingival Diseases
Connective Tissue Graft Versus Collagen Matrix.
Despite the potential role of soft tissue thickness in maintaining gingival margin stability, the existing literature has mainly focused on investigating the effect of different surgical techniques on recession coverage…
- Trial name
- NCT04678804
- Testing
- Mucogingival surgery for single recession coverage
- Where
- Italy
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Parma
Gingival Recession, Lack of Keratinized Gingiva (Disorder)
Progenitor Potential of Mesenchymal Stem Cells in Palatal Tissue Harvested From Molar and Premolar Sites
The primary purpose of this protocol is to isolate, investigate and compare the regenerative and differentiation potential of mesenchymal stem cells (MSC's) in the gingival (gum) tissue harvested from two different locations from…
- Trial name
- NCT03570333
- Testing
- progenitor potential of Gingival Mesenchymal cells
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Keratinized Tissue Gain
Comparison of the Keratinized Tissue Gain in Frenal Relocation Alone to Frenal Relocation Combined With the Application of Free Gingival Graft in High Frenum Attachment in Adults
The goal of this randomized clinical study is to compare in Adults Clinical Effect of Frenal Relocation without Free Gingival Graft Application on Keratinized Tissue Gain When Compared to Frenal Relocation with Free Gingival…
- Trial name
- Frenotomy/FGG (NCT07854132)
- Testing
- Frenotomy, Frenotomy with Free Gingival Graft
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- October University for Modern Sciences and Arts
Gingival Recession, Emdogain
Gingival Recession Coverage With and Without Emdogain
Enamel matrix proteins have been shown to play a crucial role during tooth development and its supporting tissues. This is used in periodontal surgery where regeneration of lost tissues around the teeth is intended.
- Trial name
- NCT02230787
- Testing
- Recession coverage without Emdogain, Recession coverage with Emdogain
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Bern
Gingival Recession, Localized
Effect of Vestibular Depth on Predictability of Miller Class III/ RT2 Gingival Recession Coverage
Aim of this study is to assess the influence of vestibular depth on root coverage in Miller class III/ Cairo RT2 gingival recession when treated with minimally invasive technique using connective tissue graft.
- Trial name
- NCT06000228
- Testing
- Recession coverage with CTG using minimally invasive access technique in shallow vestibule, Recession coverage with CTG using minimally invasive access technique in deep vestibule
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Recession
Platelet Rich Fibrin in the Treatment of Full Thickness Palatal Wounds
In this study it will be investigated the usefulness of Platelet-Rich Fibrin (PRF) on in the full thickness palatal graft donor site healing acceleration and in the patient's morbidity reduction.
- Trial name
- NCT04043039
- Testing
- Palatal wound bandage with PRF, Palatal wound bandage with Gelatine Sponge
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Gingival Recession
Platelet-Rich Fibrin Prepared With Titanium in the Treatment of Multiple Gingival Recessions
The aim of this study was to treat the areas with Miller Class I bilateral multiple gingival recession in the maxillary teeth using the Titanium Platelet-Rich Fibrin (T-PRF), an autogenous biomaterial applied in combination with…
- Trial name
- NCT05270941
- Testing
- COMPARISON OF PLATELET-RICH FIBRIN PREPARED WITH TITANIUM AND SUBEPITHELIAL CONNECTIVE TISSUE GRAFT
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Gingival Recession, Generalized
ASSESSMENT OF CLINICAL PARAMETERS AND LASER DOPPLER FLOWMETRY FOR THE TREATMENT OF MULTIPLE GENGIVAL RECESSIONS WITH TWO TYPES OF SUBEPITELIAL CONNECTIVE GRAFT: RANDOMIZED CLINICAL STUDY
Subepithelial connective tissue graft (SCTG) is considered the gold standard treatment for root coverage in Miller Class I and II single gingival recession.
- Trial name
- NCT03207971
- Testing
- Root coverage treatment with subepithelial connective tissue graft
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Gingival Recession
Expression of Angiogenic Biomarkers During Healing of Intra-Oral Soft Tissue Engineered Grafts
The purpose of this observational research study is to understand more about wound healing of gum tissue. This study was the biomarker study of a small cohort of study participants derived from NCT01547962 (completed).
- Trial name
- NCT01134081
- Testing
- CelTx™, Free Gingival Graft
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Michigan
Gingival Recession, Gingival Diseases
Biofiller and Gingival Phenotype Thickening
The periodontal phenotype is defined as the combination of the gingival phenotype and the thickness of the buccal bone plate (bone morphotype).
- Conditions
- Gingival Recession, Gingival Diseases, Gingival Inflammation
- Trial name
- NCT07104019
- Testing
- Biofiller Injection, connective tissue graft
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Inonu University
Gingival Recession
Root Coverage in Smokers With Acellular Dermal Matrix Graft and Enamel Matrix Derivative
Smoking has a negative effect on the predictability and stability of root coverage procedures because of decreased blood supply and fibroblast activity.
- Trial name
- NCT02135471
- Testing
- acellular dermal matrix graft, enamel matrix derivative
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- University of Sao Paulo
Missing Teeth
Assessment of Hard and Soft Tissue Changes Following XCM Versus FGG Simultaneous With Delayed Dental Implant Placement
Teeth loss are usually associated with alterations of extraction sockets result in obviously absorbed alveolar ridges and are often accompanied with soft tissue atrophy such as narrow keratinized tissue and a shallow vestibule.
- Trial name
- NCT07080177
- Testing
- Free gingival graft simultaneous with delayed implant placement, Xenogeneic collagen matrix simultaneous with delayed implant placement
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Vertically Coronally Advanced Flap Versus Coronally Advanced Flap for Miller Class I Gingival Recession
This randomized controlled clinical trial compares the clinical effectiveness of the Vertically Coronally Advanced Flap (VCAF) and the Coronally Advanced Flap (CAF), both combined with connective tissue graft (CTG) and enamel…
- Trial name
- NCT07763093
- Testing
- Coronally Advanced Flap, Vertically Coronally Advanced Flap
- Where
- Vietnam
- Volunteers
- 13 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Implant Dentistry, Connective Tissue Graft
Evaluation of Different Grafting Technique of Thin Gingival Phenotype With Delayed Dental Implants
Implant dentistry has become a fundamental aspect of modern dental practice, with its success now determined by more than just Osseo integration.
- Trial name
- NCT07892820
- Testing
- De-epithelized connective tissue graft, Sub-epithelized connective tissue graft
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Future University in Egypt
Gingivitis; Chronic
Effects of Using Miswak in Addition to Oral Hygiene Products in Patients With Gingivitis
This pilot study aims to evaluate the effects of miswak use on the oral biological environment by comparing biochemical parameters obtained from saliva and dental plaque samples collected from individuals who use miswak and…
- Trial name
- NCT07689786
- Testing
- Miswak, Toothpaste
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Gingival Recession Localized Moderate, Dental Implant
Free Soft Tissue Grafts FSTG) Using Autograft Palatal Donor Tissue vs. Xenograft Collagen Matrix (Zderm™)
Participant in this study are asked to participate because they have teeth or dental implants that were identified as having very little gum tissue and would benefit from gum tissue graft surgery.
- Trial name
- NCT07713199
- Testing
- Zderm
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Gingivitis; Chronic, Smoking
Synbiotic as an Adjunct to Mechanical Treatment of Gingivitis
The aim of this study is to evaluate the efficacy of oral administration of synbiotic tablets on the clinical parameters and the levels of selected inflammatory mediators in gingival crevicular fluid (GCF) in smokers and…
- Trial name
- NCT03455192
- Testing
- Synbiotic Supplement
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Gingival Recession
Clinical Outcomes of Enamel Matrix Derivative and Connective Tissue Graft in Modified Coronally Advanced Tunnel (MCAT)
This study investigates the treatment of gingival recession (specifically Miller Class I and II defects) using a minimally invasive surgical approach known as the modified coronally advanced tunnel (MCAT) technique.
- Trial name
- MCAT (NCT06504329)
- Testing
- Modified Coronally Advanced Tunnel (MCAT) + Subepithelial Connective Tissue Graft (SCTG), Modified Coronally Advanced Tunnel (MCAT) + Enamel Matrix Derivative (EMD)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Pain, Postoperative
Platelet Rich Fibrin VS Hyaloronic Acid in Management of Pain After Harvesting a Free Gingival Graft
Comparative study to assess the efficacy of topical application of 0.2% hyaluronic acid vs platelet rich fibrin in decreasing a postoperative pain following free gingival graft procedure . .
- Trial name
- NCT03814707
- Testing
- Topical application of 0.2% hyaluronic acid gel, Platelet rich fibrin
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- mostafa soliman
Tooth Loss
Bone Remodeling After Immediate Implant Placement With and Without Bone Grafting
This study compares two ways of placing a dental implant on the day of tooth extraction. One method will place a additional bone graft (derived from bovine bone) and the other group will not have the graft placed.
- Trial name
- NCT02174198
- Testing
- BioOss Collagen at the time of implant placement
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Columbia University