Clinical trials: Gingivitis; Chronic
Gingivitis; Chronic, Smoking
Synbiotic as an Adjunct to Mechanical Treatment of Gingivitis
The aim of this study is to evaluate the efficacy of oral administration of synbiotic tablets on the clinical parameters and the levels of selected inflammatory mediators in gingival crevicular fluid (GCF) in smokers and…
- Trial name
- NCT03455192
- Testing
- Synbiotic Supplement
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Chronic Periodontitis, Generalized, Gingivitis
Measurement of Oncostatin M, Leukemia Inhibitory Factor and Interleukin-11 Levels of Patients With Periodontal Disease
This study aims to determine Oncostatin M (OSM), Leukemia inhibitory factor (LIF), and Interleukin-11 (IL-11) levels in gingival crevicular fluid (GCF), saliva, and serum in periodontally healthy individuals and those with…
- Trial name
- NCT04597073
- Testing
- Initial Periodontal Therapy
- Volunteers
- 72 people
- Sponsor
- Ataturk University
Gingivitis; Chronic
The Effect of Probiotics on Gingivitis
The aim of the study is to assess the effect of oral probiotics containing Streptococcus salivarius M18 on gingivitis and oral hygiene in young adults.
- Trial name
- NCT05727436
- Testing
- Dentoblis
- Where
- Russia
- Volunteers
- 61 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Chronic Gingivitis, Plaque Induced
Comparative Evaluation of Guava Leaf Extract and Chlorhexidine Mouthwash in Patients With Chronic Gingivitis
The goal of this clinical trial is to compare the effectiveness of 0.15% guava (Psidium guajava) leaf extract mouth rinse with 0.2% Chlorhexidine (CHX) mouth rinse in reducing plaque accumulation, gingival inflammation, and oral…
- Trial name
- NCT07059572
- Testing
- Group A- 0.15% Guava leaf extract mouthwash group, Group B- 0.2% Chlorhexidine mouthwash
- Where
- Bangladesh
- Volunteers
- 160 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Periodontitis, Adult, Inflammation Gum
Effect of Local Cannabidiol on Clinical and Inflammatory Outcomes in Periodontal Maintenance Patients.
This study will determine if cannabidiol (CBD) has any effect on local inflammation in periodontal maintenance patients. Many successful therapies exist for the active, untreated periodontal patient.
- Trial name
- NCT05646459
- Testing
- cannabidiol, floss, proxabrush
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Gingivitis; Chronic
Hyaluronic Acid Mouthwash as Adjunct
Patients were instructed to use 2 different mouthwashes after performing professional tooth cleaning. The effect of each of the 2 mouthwashes was detected.
- Trial name
- NCT07366398
- Testing
- Hyaluoric acid mouthwash, Chlorhexidine 0,12%
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Cairo University
Periodontal Diseases, Periodontitis
Interaction Between Immune Cells and Bacteria Associated With Periodontitis
This study evaluates the interaction between host immune cells and bacteria associated with periodontitis. It comprises biological material from donors with and without periodontal disease.
- Conditions
- Periodontal Diseases, Periodontitis, Aggressive Periodontitis, Immunologic Disease
- Trial name
- NCT03225950
- Testing
- In vitro stimulation of blood with periodontitis-associated- and control bacteria, Anti-CCP- and anti-P.g.-antibodies titers, Analysis of selected single nucleotide polymorphisms (SNPs)
- Where
- 2 sites in Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Gingivitis; Chronic
The Effect of Probiotics on Gingivitis: Part 2
The aim of the study is to assess the effect of oral probiotics containing Streptococcus salivarius M18 on gingivitis and oral hygiene in young adults.
- Trial name
- NCT05919134
- Testing
- Dentoblis
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Chronic Gingivitis, Chronic Gingivitis, Plaque Induced
Efficacy of a Rinse Containing Sea Salt and Lysozyme on Biofilm and Gingival Health
This study evaluates the addition of a mouth rinse containing sea salt, xylitol and lysozyme to standardized oral health practices on biofilm formation and gingival health in a group of young adults.
- Trial name
- NCT03329105
- Testing
- Sea Salt Mouth Rinse, Standardized Oral Health Practices
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan