Clinical trials: Gingivitis, completed
Periodontitis, Gingivitis
Evaluation of Salivary Biomarker Levels in Individuals With Different Periodontal Conditions
In order to determine the pathogenesis of chronic inflammatory diseases, the levels of various cytokines are examined in tissues and fluids taken from the body.
- Conditions
- Periodontitis, Gingivitis, Periodontal Health
- Trial name
- NCT06558136
- Testing
- Saliva obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Peri-implant Mucositis, Gingivitis
Experimental Peri-implant Mucositis in Humans
This is a pilot study. The investigators hypothesize that the peri-implant soft tissue response to de novo plaque accumulation is similar to that of normal gingival tissue in the same subjects.
- Trial name
- NCT01941797
- Testing
- interruption of oral hygiene
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- UConn Health
Healthy
Clinical Efficacy of Single-Use of Peroxyl Mouthwash for Reducing Bacteria in Saliva and Bioaerosol Contamination
To evaluate the anti-bacterial, pre-procedural, clinical efficacy of Peroxyl mouthwash (1.5% hydrogen peroxide) in saliva and the reduction of bioaerosol contamination as compared to a matching placebo mouthwash (0.0% hydrogen…
- Trial name
- NCT04626778
- Testing
- Peroxyl Mouthwash
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis
To Compare the Effectiveness of Three Self-care Oral Hygiene Regimens
The study is designed to evaluate the clinical changes in gingival health by measuring the reduction of gingival bleeding and inflammation over 4 weeks.
- Trial name
- NCT04804670
- Testing
- Power device A, Power device B, Routine Oral Hygiene
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Water Pik, Inc.
Periodontal Diseases, Dental Plaque
Marginal Biofilm Distribution and Periodontal Response to Supragingival and Juxtagingival Aligner Designs
This prospective, longitudinal, within-person (split-mouth) clinical study evaluates the influence of two clear aligner trimming-line designs on marginal soft-tissue biofilm distribution and periodontal tissue response over a…
- Conditions
- Periodontal Diseases, Dental Plaque, Gingivitis
- Trial name
- BIOFILM-ALIGN (NCT07642037)
- Testing
- Supragingival aligner trimming-line, Juxtagingival festooned aligner trimming-line
- Where
- Romania
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Gingival Inflammation
Lactobacillus Reuteri Strains for Gingivitis Reduction
The aim of the present study was to investigate the potential beneficial effects in volunteer young adults of orally administered L. reuteri (DSM 17938 and ATCC PTA 5289) on gingival inflammation.
- Trial name
- NCT06234839
- Testing
- L. reuteri (DSM 17938 and ATCC PTA 5289) in form of oral tablets
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Gingivitis
A Clinical Study Investigating the Efficacy of a Stannous Fluoride Dentifrice in Improving Gingival Health After Twice Daily Use for 3 Weeks
The aim of this study is to investigate the impact of a stannous fluoride containing toothpaste in reducing gingivitis when used twice daily for a maximum for 3 weeks, when compared to a standard sodium fluoride toothpaste…
- Trial name
- NCT04050722
- Testing
- Sensodyne Repair and Protect, Colgate Cavity Protection
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Caries, Tooth Decay
Improving Oral Health With Serious Games
This study investigated if computer games can be effective at changing the way children take care of their teeth. We a museum exhibit with 3D virtual reality games called "Attack of the S.
- Conditions
- Caries, Tooth Decay, Cavities, Gingivitis
- Trial name
- AOTSM (NCT02027597)
- Testing
- Attack of the S. Mutans, Follow-up, SnowWorld
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of Washington
Periodontal Diseases, Pregnancy Gingivitis
Stress and Gingival Inflammation in Non-pregnant and Pregnant Women
Background: The purpose of the present study is to research whether stress scale scores alter with relationship to gingival inflammation and examine the impact of non-surgical periodontal therapy during pregnancy on the levels of…
- Trial name
- NCT03336957
- Testing
- periodontal treatment
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Periodontal Diseases, Gingivitis
Asprosin, Adropin, Irisin Levels in Periodontitis
The recently discovered association of the hormones 'asprosin, adropin and irisin' with obesity and metabolic status, as well as the fact that periodontal diseases are affected by obesity and nutrition bilaterally, have led us to…
- Conditions
- Periodontal Diseases, Gingivitis, Obesity
- Trial name
- NCT06250764
- Testing
- Clinical periodontal measuremenets, ELISA test from gingival crevicular fluid (GCF)
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- AYSAN LEKTEMUR ALPAN
Gingival Inflammation
Evaluation of The Effect of Live Probiotic Cultures Present in Fermented Dairy Product (Yogurt) Versus The Effect of Freeze-Dried Probiotic Sachets on Gingival Bleeding of Adolescents
To evaluate the effect of probiotics supplied in two different forms (dairy products containing probiotics as yogurt and freeze-dried synthetic probiotics sachets) on improving gingival condition and caries potentiality of dental…
- Trial name
- NCT03640065
- Testing
- freeze-dried probiotic sachets, fermented dairy product ( yogurt)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingivitis
Clinical Evaluation and Assesment of Ginigivitis Patients Treated by Yarrow Natural Extract in Compare to a Contro Group
A double-blind, prospective, randomized, intra-individual comparative, single-center clinical study was conducted. Participants were placed in parallel groups, and the study was performed in the Department of Operative Dentistry…
- Trial name
- NCT06070571
- Testing
- Yarrow and moringa mixture
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Deraya University
Gingival Pocket
Gingival Displacement by Polytetrafluoroethylene & Conventional Retraction Cord
To achieve harmony between restoration and surrounding periodontium, soft tissue management plays a pivotal role. Various Gingival displacement techniques show varying results in achieving the goals of displacement.
- Trial name
- NCT04087226
- Testing
- PTFE Retraction Cord
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Gingivitis
A Clinical Study to Assess the Plaque and Gingivitis Effects of a Stannous Fluoride Dentifrice
The objective of this clinical study is to assess the effects of a 0.454% stannous fluoride dentifrice on gingivitis and plaque after 3 months when compared to a negative control.
- Trial name
- NCT03936569
- Testing
- Marketed Toothpaste, Marketed Cavity Protection Toothpaste
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Halitosis, Gingivitis
Day Long Prevention of Oral Malodor With a Palatal Patch (SmellX) Containing A Herbal Formula
In a previous study the prevention of halitosis by the herbal formula and delivery system (SmellX), were established both in vitro and clinicaly. The duration of relief was established as long as 8 hours.
- Trial name
- SmellX (NCT01388023)
- Testing
- herbal formula for fresh breath
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Gingivitis, Mouth Diseases
Clinical Effects of Tooth Powder on Gingivitis
Dental plaque, known as dental biofilm, is implicated as the primary etiological agent responsible for oral inflammatory diseases.
- Trial name
- Toothpowder (NCT01902095)
- Testing
- Tooth powder, Tooth paste (control)
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Sheikh Zayed Federal Postgraduate Medical Institute
Gingivitis
A Controlled Clinical Study to Determine the Gingivitis Benefit of Flossing
This is a randomized, controlled, examiner-blind, parallel group, four week clinical study comparing brushing plus flossing to brushing alone in 60 healthy adults with pre-existing gingivitis.
- Trial name
- NCT00964860
- Testing
- Glide dental floss
- Where
- Guatemala
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Gingivitis
Incentives for Daily Tooth Brushing to Reduce Gingivitis
In this randomized controlled study, the investigators compare two classes of behavioral approaches to change habits and health outcomes with an application to dental health: cognitive vs. behavioral financial incentives.
- Trial name
- NCT02160418
- Testing
- Financial Incentives, Cognitive Incentives, Financial and Cognitive Incentives
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Gingivitis, Dental Plaque
Comparison Of Clinical Effects Of Listerine And Chlorhexidine Mouth Wash In Patients Undergoing Fixed Orthodontic Treatment
This randomized clinical trial aims to compare the effectiveness of Listerine and Chlorhexidine mouthwashes in improving periodontal health in patients undergoing fixed orthodontic treatment.
- Trial name
- NCT07119840
- Testing
- Listerine Mouthwash Product, Chlorhexidine mouthwash
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Gingivitis, Orthodontic Treatment
Effect of Individually Trained Oral Prophylaxis (iTOP) on Gingival Health in Orthodontic Patients
This randomized controlled clinical trial aims to evaluate the effectiveness of individualized oral hygiene education using the Individually Trained Oral Prophylaxis (iTOP) method compared with conventional oral hygiene…
- Trial name
- NCT07468773
- Testing
- Individually Trained Oral Prophylaxis (iTOP) Oral Hygiene Training, Conventional Oral Hygiene Instruction
- Where
- United Arab Emirates
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University