Clinical trials: Gingivitis, completed
Plaque, Gingivitis
A Pilot Study to Evaluate a Method for Plaque When Comparing Stannous Fluoride Toothpaste to a Regular Dentifrice
This study will evaluate the sensitivity of an assay and its ability to split a marketed stannous fluoride toothpaste versus a negative control.
- Trial name
- NCT02543060
- Testing
- stannous fluoride toothpaste, cavity protection toothpaste
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Gingivitis, Orthodontics
Effectiveness of Different Types of Toothbrushes on Periodontal Health in Orthodontic Patients
The goal of this clinical trial is to compare the effectiveness of different toothbrushes in patients with fixed orthodontic appliances who have gingival inflammation. The main questions it aims to answer are: 1.
- Trial name
- NCT06510179
- Testing
- Toothbrushing
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Okan University
Dental Plaque, Saliva Altered
Effects of Two Sugar Substituted Chewing Gums on Caries and Gingivitis Variables
The purpose of this study is to determine the effect of three times a day mastication, during a follow-up period of 4 weeks, of two sugar-substituted chewing gums on various factors associated with dental caries and gingivitis.
- Conditions
- Dental Plaque, Saliva Altered, Gingivitis
- Trial name
- NCT01578603
- Testing
- xylitol, casein phosphopeptide amorphous calcium phosphate complex
- Where
- Colombia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Gingivitis
Oral Hygiene and Systemic Inflammation (Perio-Hygiene 1.0)
The purpose of the study is to evaluate the impact of oral hygiene changes (drastic plaque and gingival inflammation reduction) on markers of systemic inflammation and indicators of oral health related quality of life and other…
- Trial name
- NCT03848351
- Testing
- Oral Hygiene Instruction (OHI), Professional supragingival scaling and polishing
- Where
- Italy
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Gingivitis, Dental Plaque Accumulation
Essential Oils Mouth Rinse and Dental Floss: Efficacy on Interproximal Gingivitis and Dental Plaque Accumulation
It is difficult to obtain patient's compliance with regular interproximal dental hygiene. Dental floss is recognized as an effective procedure to remove dental plaque and prevent gingivitis in the space between teeth, but it is…
- Trial name
- NCT01236963
- Testing
- Essential oils mouthrinse, Dental Floss
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Gingivitis, Dental Plaque
A Clinical Comparison of an Experimental Power Brush Compared to a Manual Toothbrush
The objective of the study is to evaluate and compare the efficacy of an experimental power brush to a regular manual brush in the reduction of gingivitis and dental plaque over an 8 week period by using the Modified Gingival…
- Trial name
- NCT03624647
- Testing
- Power toothbrush, Manual toothbrush
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Gingivitis, Dental Plaque
A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health
The aim of this analysis was to compare gingivitis- and plaque-reduction efficacy from randomized controlled trials (RCTs) up to six months long evaluating oscillating-rotating, sonic, and manual toothbrushes
- Trial name
- NCT05594004
- Testing
- Oscillating-rotating electric toothbrush, Sonic electric toothbrush, Manual toothbrush
- Where
- United States
- Volunteers
- 2,929 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Periodontal Diseases
Comparison of Salivary Biormarkers Levels With Periodontal Clinical Parameters in Smokers and Non-Smokers With Different Periodontal Diseases
To better understand the pathogenesis of chronic inflammatory diseases, the levels of various cytokines are commonly analyzed in tissues and biological fluids collected from the body.
- Trial name
- NCT06459037
- Testing
- Saliva obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Plaque
A Clinical Study to Evaluate Effects of an Oral Rinse on Plaque and Gingivitis
Rinse contains an anti-plaque agent that helps prevent the accumulation of dental plaque associated with gingivitis.
- Trial name
- NCT03421145
- Testing
- 3M™ Oral Rinse, Vehicle Control Oral Rinse, PerioShield™ Oral Health Rinse
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Gingival Inflammation
Lactobacillus Reuteri Strains for Gingivitis Reduction
The aim of the present study was to investigate the potential beneficial effects in volunteer young adults of orally administered L. reuteri (DSM 17938 and ATCC PTA 5289) on gingival inflammation.
- Trial name
- NCT06234839
- Testing
- L. reuteri (DSM 17938 and ATCC PTA 5289) in form of oral tablets
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Gingivitis, Plaque, Dental
Antiplaque Efficacy of Two Novel Commercially Available Herbal Toothpastes.
Maintaining proper oral hygiene is essential in the prevention of oral as well as general illness. The use of herbal medicine in dentistry is growing exponentially over the years.
- Trial name
- NCT05363956
- Testing
- salvadora, Eucalyptus Oil
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ajman University
Gingivitis
Compare Anti-inflammatory Dentifrices
Plaque induced gingivitis
- Trial name
- NCT00762528
- Testing
- Triclosan/Copolymer/fluoride toothpaste, Sodium monofluorophosphate toothpaste
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis Infection
Chlorhexidine (CHX) Mouthwash With or Without an Anti-Discoloration System (ADS) During Experimental Gingivitis
Recently, a chlorhexidine product with an anti-discoloration system (ADS) was launched in the market. A comparative study was done to confirm the effectiveness of 0.2% chlorhexidine with ADS. The study was single-blinded.
- Trial name
- NCT07696364
- Testing
- Experimental gingivitis model
- Where
- Switzerland
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Bern
Gingivitis, Plaque
A Study of Experimental Mouthwashes
The purpose of this study is to evaluate the safety and efficacy of experimental mouthwash formulations compared to a hydroalcohol control mouthwash and a positive control mouthwash for the reduction of gingivitis and plaque when…
- Trial name
- NCT05121909
- Testing
- Colgate (R) Cavity Protection Toothpaste, Colgate (R) Cello Toothbrush, Prototype 1 Mouthwash
- Where
- Canada
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Plaque, Gingivitis
The Clinical of Stannous Fluoride Toothpaste and a Newly Designed Toothbrush Compared to Colgate Cavity Protection Toothpaste and a Regular Toothbrush in Reducing Plaque and Gingivitis.
Qualified subjects will be enrolled and randomly assigned to either of the two study groups based on their initial Plaque and Gingivitis scores.
- Trial name
- NCT06427499
- Testing
- Stannous fluoride toothpaste, Colgate Cavity Protection Toothpaste
- Where
- Thailand
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Adolescent Behavior, Dental Plaque
Evaluating the Effectiveness of a Cognitive Behavioral Intervention (CBI)
This is a Phase III, randomized, one-center, three arm parallel group, open label and single blind clinical study to evaluate the effectiveness of a cognitive behavioral intervention (CBI) adjunctive to a smart powered toothbrush…
- Conditions
- Adolescent Behavior, Dental Plaque, Gingivitis, Cognitive Change
- Trial name
- NCT05782348
- Testing
- Cognitive behavioral intervention, Colgate smart toothbrush
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Howard University
Gingivitis
Comparisons of Efficacy of Triphala and Chlorhexidine Mouthwash Against Plaque Accumulation and Gingivitis.
Gingivitis is one of the commonly prevalent oral diseases worldwide which is caused by the bacterial biofilm adhering to the teeth surfaces. Chlorhexidine is the antimicrobial agent most familiar to dental professionals.
- Trial name
- NCT07426393
- Testing
- 6% Triphala mouthwash, .2% chlorhexidine mouthwash
- Where
- Bangladesh
- Volunteers
- 220 people
- Sponsor
- Bangladesh Medical University
Gingivitis
A Three Month Bleeding-Model Clinical Study
The objective of the study is to evaluate the gingivitis control benefit of an established stannous fluoride containing toothpaste relative to a negative control dentifrice.
- Trial name
- NCT05916521
- Testing
- 0.454% stannous fluoride, 0.76% sodium monofluorophosphate, 0.454% stannous fluoride AM and 0.76% sodium monofluorophosphate PM
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Halitosis, Gingivitis
Day Long Prevention of Oral Malodor With a Palatal Patch (SmellX) Containing A Herbal Formula
In a previous study the prevention of halitosis by the herbal formula and delivery system (SmellX), were established both in vitro and clinicaly. The duration of relief was established as long as 8 hours.
- Trial name
- SmellX (NCT01388023)
- Testing
- herbal formula for fresh breath
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Hyperlipidemia, Periodontitis, Gingivitis
PERIODONTAL DISEASE AND HYPERLIPIDEMIA
The investigators hypothesized that hyperlipidemia as an unfavourable levels of lipoprotein subfractions have deleterious impact on the development of periodontal infection by altering oxidative stres status of periodontal…
- Trial name
- NCT02808130
- Testing
- hyperlipidemia, periodontitis, gingivitis
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University