Clinical trials: Girls
Smoke Inhalation Patients
Impact of Hydroxocobalamine on Outcome of Smoke Inhalation Injury Admitted to the ICU
In Europe, hydroxocobalamin (cyanokit) has been used for suspicion of cyanide intoxication associated with the inhalation of fire smoke (1). However, the impact of hydroxocobalamin on outcome has never been thoroughly evaluated.
- Trial name
- COB-AKI (NCT03558646)
- Testing
- There is no intervention planned (observational)
- Where
- France
- Volunteers
- 739 people
- Sponsor
- Saint-Louis Hospital, Paris, France
Postpartum Hemorrhage
Does the Rapid Intravenous Administration of Oxytocin After Delivery of the Baby Decrease the Bleeding During Cesarean Section in Women at Risk of Bleeding During Cesarean Section?
Oxytocin is normally given either rapidly into the vein (bolus) or put into an intravenous bag and administered more slowly, after delivery of the baby by cesarean section. Both of these methods are commonly used.
- Trial name
- NCT00257803
- Testing
- Oxytocin, Saline solution
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
HIV Infected Women, Healthy Women Volunteers
Study of Immunity at the Genital Mucosa of HIV-1 Infected and Healthy Women
Current knowledge on mucosa, especially genitals in women, however, remain inadequate, especially regarding defense mechanisms and possibilities for a vaccine to induce an active immune response at mucosal front door of the most…
- Trial name
- MUCOVAC (NCT01715103)
- Testing
- vaginal swabs by washing and cytobrush
- Where
- 2 sites in France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Metastatic Renal Cell Carcinoma
Velcade and Sorafenib in Unresected or Metastatic Renal Cell Carcinoma
This is an open label, non-randomized, single arm phase II study. The primary objective of this study is to investigate the efficacy of combination of sorafenib and VELCADE® (bortezomib).
- Trial name
- NCT01100242
- Testing
- Velcade and Sorafenib
- Where
- 3 sites in United States
- Volunteers
- 17 people
- Sponsor
- New Mexico Cancer Research Alliance
Smoking, Smoking Cessation
Remote Incentives for Smoking Cessation Among AN Pregnant Women
Cigarette smoking during pregnancy increases risk for catastrophic pregnancy complications, growth retardation, other adverse infant health problems, and later-in-life chronic conditions.
- Trial name
- NCT05019170
- Testing
- Smartphone-based Financial Incentives, Best Practices
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Fungal Infection
A Drug-Drug Interaction Study of CYP3A4 Inhibition and Pan-CYP Induction on APX001
This is a Phase 1, open-label study to evaluate the drug-drug interaction potential of a strong CYP3A4 inhibitor (itraconazole) and a pan-CYP inducer (rifampin) on APX001 in two parallel groups of healthy subjects.
- Trial name
- NCT04166669
- Testing
- APX001, Itraconazole, Rifampin
- Where
- 2 sites in Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Basilea Pharmaceutica
Maternal Health Care
Evaluating the Impact of a Symptom Checker on Healthcare-seeking Decisions: a Mixed-Methods Study
The goal of this study is to evaluate the integration of a symptom checker (SC) into the MomConnect (MC) platform to support maternal healthcare in South Africa.
- Trial name
- SAFEMOM (NCT06790069)
- Where
- South Africa
- Volunteers
- 968 people
- Sponsor
- Ada Health GmbH
Endometritis
Doxycycline Prophylaxis at Vacuum Aspiration Trial
This study is a randomized, double-blinded, controlled trial comparing two regimens of doxycycline for the prevention of infection after surgical abortion.
- Trial name
- Tu Du Doxy (NCT00547170)
- Testing
- Doxycycline pre-operatively, Doxycycline post-operatively
- Where
- Vietnam
- Volunteers
- 1,000 people
- Sponsor
- University of Pittsburgh
Alcohol Misuse, HIV
Gathering Online for Dialogue and Discussion to Enhance Social Support
The goal of this trial is to test a modified mobile health intervention (with a group component) relative to a mobile health intervention in a two-arm randomized trial with up to 500 young women who are human immunodeficiency…
- Conditions
- Alcohol Misuse, HIV, Sexually Transmitted Infections, Pre-exposure Prophylaxis
- Trial name
- GODDESS (NCT05753683)
- Testing
- mHealth-Women's CoOp, Virtual Group
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- RTI International
Kidney Transplantation, End Stage Renal Disease
Live Kidney Donor Study
Kidney transplants from living donors now account for 40% of all the kidney transplants done in the United States. However, the current information on how donating a kidney can affect the donor's long term health needs further…
- Trial name
- NCT00608283
- Where
- 3 sites in United States
- Volunteers
- 8,951 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Breast Cancer
Efficacy of Exercise Using Connected Activity Trackers and Therapeutic Education in Localized Breast Cancer
The 3-year DISCO study aims to systematically implement physical activity in breast cancer patients. The primary objective is to investigate the efficacy of a connected device (personalized non-supervised exercise program…
- Trial name
- DISCO (NCT03529383)
- Testing
- Connected device, Therapeutic education
- Where
- 3 sites in France
- Volunteers
- 436 people
- Sponsor
- Centre Leon Berard
Endometrial Cancer
Adjuvant Sequential & Concurrent CarboTaxol + Radiotherapy for High Risk Endometrial Cancer
The purpose of this trial is to evaluate the safety of sequential and concurrent carboplatin and paclitaxel with adjuvant external beam radiotherapy for locally advanced endometrial cancer.
- Trial name
- NCT03935256
- Testing
- Carboplatin and Paclitaxel, Radiation Therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Loyola University
Cervical Intraepithelial Neoplasia, Cervical Cancer
Efficacy, Immunogenicity and Safety Study of Recombinant Human Papillomavirus Vaccine(6,11,16,18,31,33,45,52,58 Type)(E.Coli)
This phase III clinical study was designed to evaluate the efficacy,immunogenicity and safety of Recombinant Human Papillomavirus Vaccine (6,11,16,18,31,33,45,52,58 Type)(E.Coli) manufactured by Xiamen Innovax Biotech CO., LTD.…
- Conditions
- Cervical Intraepithelial Neoplasia, Cervical Cancer, Condylomata Acuminata
- Trial name
- NCT04537156
- Testing
- Nonavalent HPV vaccine, Bivalent HPV vaccine
- Where
- 2 sites in China
- Volunteers
- 9,327 people, healthy volunteers welcome
- Sponsor
- Xiamen University
Premenstrual Syndrome
Dual-Task Postural Stability in Women With Premstrual Syndrome: A Within-Subject Comparative Study
This within-subject repeated-measures study investigated dual-task postural stability in women with premenstrual syndrome (PMS) by comparing performance during the PMS and non-PMS phases of the menstrual cycle.
- Trial name
- NCT07801651
- Testing
- PMS Group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Deraya University
Urinary Incontinence, Urinary Incontinence,Stress
Adjustable Continence Therapy (ACT) for the Treatment of Female SUI
A prospective, single arm, non-randomized, multicenter, prospective case-series trial. The purpose of this trial is to demonstrate the safety and effectiveness of using the Adjustable Continence Therapy (ACT) to provide a…
- Trial name
- NCT04248283
- Testing
- Adjustable Continence Therapy for Women (ACT)
- Where
- 8 sites in United States, France
- Volunteers
- 167 people
- Sponsor
- Uromedica
Hypertension, Chronic Kidney Disease
Renal Nerve Ablation in Chronic Kidney Disease Patients
In patients with treatment resistent hypertension renal nerve ablation emerged as an effective interventional approach of treating hypertensive disease with a progressively increasing fall in blood pressure.
- Trial name
- NCT01442883
- Testing
- Simplicity Catheter
- Where
- 2 sites in Germany
- Volunteers
- 27 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Colon Cancer, Ovarian Cancer
Exercise Intervention Prior to CRS-HIPEC: Feasibility & Impact
Our objective is to initiate an exercise program for patients with advanced GI or Gyn cancer, as prehabilitation prior to surgery.
- Conditions
- Colon Cancer, Ovarian Cancer, GI Cancer, Gynecologic Cancer
- Trial name
- NCT04731441
- Testing
- Home-based Exercise Program Prior to CRS-HIPEC, Exercise Education
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Milton S. Hershey Medical Center
Intestinal Microbiota, Vaginal Microbiota
Characteristics of Vaginal and Intestinal Microbiota and Cervical HPV Infection
There are different microbial communities on the surface of human body (skin, hair, nails, etc.) and in the cavity connected with the outside world.
- Conditions
- Intestinal Microbiota, Vaginal Microbiota, HPV Infection
- Trial name
- NCT05003505
- Testing
- Follow up
- Where
- 8 sites in China
- Volunteers
- 651 people, healthy volunteers welcome
- Sponsor
- Fujian Maternity and Child Health Hospital
Adjuvant Chemotherapy, Ovarian Neoplasms
Efficacy and Safety of PEG-rhG-CSF Secondary Prophylaxis vs. Therapeutic Administration in Patients With Ovarian Cancer
This study is a multicenter, open-label, randomized clinical trial. Patients with ovarian cancer receiving postoperative adjuvant chemotherapy were eligible to enroll in this study.
- Conditions
- Adjuvant Chemotherapy, Ovarian Neoplasms, Ovarian Cancer
- Trial name
- NCT03858166
- Testing
- PEG-rhG-CSF
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Shandong University
Insulin Resistance, Oxidative Stress
Microencapsulated Fish Oil or Conjugated Linoleic Acid in Metabolic Syndrome
Our aim was to assess the effects of a hypocaloric diet, including diet fruit jelly with microencapsulated fish oil or conjugated linoleic acid or placebo, on anthropometry, body composition, insulin resistance and lipid profile…
- Conditions
- Insulin Resistance, Oxidative Stress, Lipid Profile, Blood Pressure
- Trial name
- NCT02183922
- Testing
- microencapsulated conjugated linoleic acid, microencapsulated fish oil, light fruit jam
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
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