Clinical trials: Girls
Metastatic Bladder Cancer, Peripheral Neuropathy
Acupuncture and Exercise for EV-Pembro-Induced Peripheral Neuropathy
The goal of this study is to evaluate the feasibility and preliminary efficacy of a combined acupuncture and exercise intervention for the management of chemotherapy-induced peripheral neuropathy (CIPN) in participants with…
- Conditions
- Metastatic Bladder Cancer, Peripheral Neuropathy, Advanced Urothelial Cancer, Metastatic Urothelial Cancer
- Trial name
- ACE (NCT07548476)
- Testing
- Acupuncture, Exercise
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dana-Farber Cancer Institute
Membranous Nephropathy
Rituximab in Membranous Nephropathy
Membranous glomerulopathy (MN) is a common immune-mediated glomerular disease and the leading cause of nephrotic syndrome in Caucasian adults.
- Trial name
- NCT00425217
- Testing
- Rituximab
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Lynch Syndrome, Endometrial Cancer
EC_ItaLynch: Mainstreaming the Diagnosis of Lynch Syndrome
Lynch syndrome (LS) is the most common cause of hereditary endometrial cancer (EC) and is associated with an increased risk of colorectal (CRC), ovarian, gastric, small bowel and urinary tract cancer.
- Trial name
- EC_ItaLynch (NCT06501417)
- Testing
- mainstreaming
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lactation
Growth Hormones and Cells in Human Milk Depending on Gestational Age
Human breast milk contains growth factors including neurotrophins and cells with neuroprotective potential. Concerning growth factors milk of preterms differs significantly from term milk.
- Trial name
- BMProfile (NCT02662517)
- Where
- Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University Hospital of Cologne
Peripartum Anemia
Impact of Intraoperative Cell Salvage
Patients presenting for elective cesarean section will be screened for pre-procedural anemia. If the potential subject meets the selection criteria they will be presented with the option of participating in the study.
- Trial name
- NCT06240117
- Testing
- Intraoperative cellular salvage
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Family Planning
Misoprostol Prior to IUD Insertion in Nullipara
The use of misoprostol at a dose of 400 µg administered vaginally four hours prior to IUD insertion increased the ease of insertion and reduced the incidence of pain during the procedure, although the frequency of cramps…
- Trial name
- NCT03490617
- Testing
- Vaginal misoprostol
- Where
- Brazil
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Pregnancy Related, Anesthesia
Pre-oxygenation With High-flow Nasal Cannula in Caesarian Section Under General Anesthesia
The investigators and other groups have demonstrated that high-flow nasal oxygen used during preoxygenation for emergency surgery is at least equally effective as preoxygenation compared to standard tight fitting mask.
- Conditions
- Pregnancy Related, Anesthesia, Oxygen Deficiency, Cesarean Section Complications
- Trial name
- PRIOROB (NCT04711317)
- Testing
- Nasal high flow oxygen
- Where
- 4 sites in Sweden
- Volunteers
- 34 people
- Sponsor
- Karolinska University Hospital
Trichomonas Vaginitis, Bacterial Vaginitis
Refining Treatment Options for Trichomonas Vaginalis Infection: A Comparative Analysis of Metronidazole and Secnidazole
This is a multi-centered, randomized, open-label, parallel, phase IV clinical trial comparing the effectiveness and cost-effectiveness of oral multi-dose metronidazole (MTZ) and oral single-dose secnidazole (SEC) for the…
- Trial name
- NCT06261840
- Testing
- Metronidazole 500 mg, Secnidazole 2000 MG
- Where
- 4 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Tulane University
Preeclampsia Postpartum
Losartan for Improved Vascular Endothelial Function After Preeclampsia
Women who develop preeclampsia during pregnancy are more likely to develop and die of cardiovascular disease later in life, even if they are otherwise healthy.
- Trial name
- LIVE-PE (NCT04632589)
- Testing
- Losartan Potassium
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Anna Stanhewicz, PhD
Glomerulonephritis, Proteinuria
Empagliflozin in Patients With Glomerulonephritis
Sodium-glucose cotransporter 2 (SGLT2) inhibitors are newly developed antihyperglycemic medications. In addition to their glucose lowering properties, they have been shown to have favourable effects on the cardiovascular and…
- Trial name
- NCT05283057
- Testing
- Empagliflozin 25 MG
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Metastatic Breast Carcinoma, Stage IIIB Breast Cancer AJCC v7
Fulvestrant With or Without Bortezomib in Patients With Inoperable Locally Advanced or Metastatic Estrogen Receptor Positive Breast Cancer
This randomized phase II trial studies how well fulvestrant works with or without bortezomib in treating patients with estrogen receptor positive breast cancer that has spread to other places in the body and cannot be removed by…
- Conditions
- Metastatic Breast Carcinoma, Stage IIIB Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7, Stage IV Breast Cancer AJCC v6 and v7
- Trial name
- NCT01142401
- Testing
- Bortezomib, Fulvestrant, Laboratory Biomarker Analysis
- Where
- 21 sites in United States
- Volunteers
- 118 people
- Sponsor
- National Cancer Institute (NCI)
Ovarian Neoplasm
Phase II CT-2103/Carboplatin in Ovarian Cancer
The purpose of this study is to evaluate the safety and efficacy of CT-2103 (poly(L)glutamate-paclitaxel) in combination with carboplatin for the treatment of patients with Stage III or IV ovarian or primary peritoneal cancer.
- Trial name
- NCT00069901
- Testing
- CT-2103 (poly(L)glutamate-paclitaxel), carboplatin
- Where
- 17 sites in United States
- Volunteers
- 82 people
- Sponsor
- CTI BioPharma
Overactive Bladder
The Efficacy of Botulinum Toxin in OVERACTIVE Bladder
To assess the efficacy of botulinum toxin injection in overactive bladder.
- Trial name
- NCT03888001
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Female Infertility of Tubal Origin
Intracervical Lidocaine Versus Intramuscular Diclofenac for Pain Relief in HSG in a Tertiary Hospital in Kano
This study compares the effect of intracervical block with 1% lidocaine and intramuscular diclofenac 75mg in decreasing pain perception during hysterosalpingography.
- Trial name
- NCT02918812
- Testing
- Intracervical lidocaine, Intramuscular Diclofenac
- Where
- Nigeria
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Bayero University Kano, Nigeria
Eating Disorders in Adolescence
The Peer-Delivered "Mind. Body. Voice." Program for High School Women (Mbv) - Remote
This study will evaluate the impact of a program (called mind. body. voice. or "mbv") that was collaboratively designed by youth, educators, and researchers, informed by the Body Project (Becker et al., 2013; Stice et al., 2019)…
- Trial name
- NCT04591912
- Testing
- mind. body. voice
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Breast Cancer Female, Quality of Life
Effects of Aerobic Exercise on Cancer-Related Biomarkers, Functional Capacity, Cognitive Status and Quality of Life in Women With Breast Cancer
This study aims to emphasize the exercise-induced changes in some circulating biomarkers (CRP, IGF-1(insulin like growth factor), insulin, leptin, IL-6(interleukin-6) , TNF-α(tumor necrosis factor), adiponectin), quality of life…
- Conditions
- Breast Cancer Female, Quality of Life, Survivorship
- Trial name
- NCT06540612
- Testing
- Aerobic exercise, Physical activity counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Hasan Kalyoncu University
Thoracic Surgery, Acute Kidney Injury
Influence of Preoperative Fluid Intake on the Onset of Postoperative Acute Kidney Injury
To investigate the influence of preoperative fluid and food intake in cardiac surgery patients on the development of postoperative AKI.
- Conditions
- Thoracic Surgery, Acute Kidney Injury, Critical Care
- Trial name
- HYDRATE-CSX (NCT03938181)
- Where
- Germany
- Volunteers
- 320 people
- Sponsor
- RWTH Aachen University
End-Stage Renal Disease
Clinical Observation of the Performance of Artis Dialysis System, ArtiSet PrePost and Ultra HDF Line in Treatments of Patients With End-Stage Renal Disease (ESRD)
The incidence and prevalence of chronic kidney disease are increasing worldwide, as is the number of patients progressing to End-Stage Renal Disease (ESRD).
- Trial name
- NCT03859830
- Testing
- Artis Dialysis System, ArtiSet PrePost and Ultra HDF Line, AK200 Ultra S, extracorporeal circulation conduct of blood purification
- Where
- 7 sites in China
- Volunteers
- 276 people
- Sponsor
- Vantive Health LLC
Patients With Newly Diagnosed Small Renal Masses(<4cm)
The Natural History of Small Renal Masses
There is a rising incidence of incidentally detected small renal tumours due to improved imaging techniques. Traditionally, patients diagnosed with these small renal masses undergo surgery and therefore there is limited data…
- Trial name
- NCT01305330
- Where
- Canada
- Volunteers
- 137 people
- Sponsor
- University Health Network, Toronto
Gestational Diabetes
The Effects of Resistance Exercises in Glycemic Control of Women With Gestational Diabetes
The object of this study is to evaluate patients with a diagnosis of GD who are included in a program of RE carried out with rubber tubes, comparing the frequency of women who will use insulin in the group who will participate in…
- Trial name
- NCT00815828
- Testing
- Resistance exercises
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- University of Sao Paulo
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