Clinical trials: Glaucoma, Narrow Angle
Glaucoma Eye, Open-angle Glaucoma
Quality of Life After Glaucoma Surgery: Evaluating the Patient Perspective Across Surgical Options
Glaucoma surgery currently relies on a wide therapeutic arsenal, ranging from conventional filtering surgeries to minimally invasive glaucoma surgery (MIGS).
- Conditions
- Glaucoma Eye, Open-angle Glaucoma, Closed-Angle Glaucoma, Pseudo Exfoliative Syndrome
- Trial name
- G-SCOPE (NCT07303257)
- Testing
- NEI-VFQ-25 (National Eye Institute Visual Function Questionnaire-25).
- Where
- France
- Volunteers
- 132 people
- Sponsor
- Hospices Civils de Lyon
Open Angle Glaucoma, Narrow Angles
Comparison of Gonioscopy With Cirrus and Visante
The aim of this study is to analyze similarities and evaluate interchangeability of Visante and Cirrus OCT (optical coherent tomography)and to compare agreement between gonioscopy and the two systems for evaluation of anterior…
- Conditions
- Open Angle Glaucoma, Narrow Angles, Angle Closure Glaucoma
- Trial name
- ASOCT (NCT01895686)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Wills Eye
Angle Closure Glaucoma
Comparing Nd:YAG Laser and Sequential Double Frequency YAG-Nd:YAG Laser Iridotomy
No single type of laser or set of laser parameters is appropriate for all type of irides. Pure Nd:YAG laser iridotomy is very effective in the light color irides. It was considered as the gold standard for iridotomy.
- Trial name
- NCT02474238
- Testing
- The sequential technique, The pure Nd:YAG laser technique
- Where
- Thailand
- Volunteers
- 82 people
- Sponsor
- Prince of Songkla University
Glaucoma,Primary Open-Angle ,Primary Angle Closure
Comparison of Optical Coherence Tomography Angiography Microvascular Changes in Primary Open Angle and Primary Angle Closure Glaucoma
This work aims to study the peripapillary and macular microvascular changes in primary open angle and primary angle closure glaucoma using Optical Coherence Tomography Angiography (OCTA).
- Trial name
- NCT06000176
- Testing
- Optical coherence tomography angiography
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Omar Said
Glaucoma
IOP Pattern in Primary Angle Closure and Primary Angle Closure Glaucoma Patients, Before and After LPI
The purpose of the study is to determine the relationship of the intraocular pressure patterns recorded during 2 sessions using Triggerfish, before and after elective laser peripheral iridotomy in angle closure glaucoma patients
- Trial name
- NCT01906151
- Testing
- SENSIMED Triggerfish®
- Where
- France
- Sponsor
- Sensimed AG
Glaucoma, Open-Angle, Glaucoma, Narrow Angle
Study of a Cilioscleral Interposition Device (CID) SV22 in Patients With Primary Open Angle Glaucoma and Narrow Angle Glaucoma
The purpose of this study is to evaluate the safety and effectiveness of implanting a new version of an interposition supraciliary implant (SV22) as a stand-alone therapy for lowering intraocular pressure (IOP) in patients with…
- Trial name
- SAFARI 3 (NCT05236439)
- Testing
- Interposition supraciliary implant
- Where
- Armenia
- Volunteers
- 57 people
- Sponsor
- Ciliatech
Primary Angle-Closure Glaucoma
Vitreous Zonule in Primary Angle-Closure Glaucoma
This study aims to investigate the role of the vitreous zonule (VZ) in the pathogenesis of primary angle-closure glaucoma (PACG) and to explore the feasibility of three-dimensional ultrasound biomicroscopy (3D-UBM) for imaging…
- Trial name
- NCT07523139
- Where
- China
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Glaucoma, Narrow Angle
Intraocular Pressure Control After Anterior Segment Laser - Comparison Between 2 Drugs
The purpose of this study is to compare the intra-ocular (IOP) control efficacy between brimonidine 0.1% vs. 0.2% after laser peripheral iridotomy (LPI).
- Trial name
- NCT01417858
- Testing
- YAG laser peripheral iridotomy
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Universidade Federal do Paraná
Primary Open Angle Glaucoma, Primary Angle Closure Glaucoma
Patch Graft Material Safety and Effectiveness in Covering Glaucoma Drainage Device Tube
The investigators hypothesize that KeraSys is a safe as Tutoplast to cover the tube of the Molteno 3 glaucoma drainage device during surgery
- Conditions
- Primary Open Angle Glaucoma, Primary Angle Closure Glaucoma, Pseudoexfoliation Glaucoma, Pigmentary Glaucoma
- Trial name
- NCT01301378
- Testing
- Molteno 3 glaucoma drainage shunt
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wills Eye
Acute Primary Angle-closure Glaucoma
Corneal Densitometry in Acute Primary Angle Closure Glaucoma
Purpose: Our purpose was to investigate the laser peripheral iridotomy (LPI) induced changes in corneal densitometry in acute primary angle closure glaucoma (PACG) cases during the post-laser 1 month period.
- Trial name
- NCT04254458
- Testing
- Corneal densitometry
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Ulucanlar Eye Training and Research Hospital
Angle-closure Glaucoma, Minimally Invasive Glaucoma Surgery
Biometric Changes After Intervention of Anterior Chamber Angle : an Observational Study
The drainage angle in the anterior chamber of the eye mediates the outflow of aqueous humor, and pathological changes here can lead to high intraocular pressure and glaucoma.
- Conditions
- Angle-closure Glaucoma, Minimally Invasive Glaucoma Surgery, Goniosynechialysis, Goniotomy
- Trial name
- NCT06492538
- Testing
- various types of angle interventions
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Primary Angle Closure Glaucoma
The Effect of Phacoemulsification on Intraocular Pressure in Primary Angle Closure Glaucoma (PACG) Patients At Phanat Nikhom Hospital, Chonburi Province
BACKGROUND: Primary angle closure glaucoma (PACG) is one of a leading cause of blindness worldwide including Thailand. This problem impact to the overall health of people and health care system.
- Trial name
- NCT06252246
- Testing
- Phacoemulsification machine
- Where
- Thailand
- Volunteers
- 121 people
- Sponsor
- Phanatnikhom Hospital
Glaucoma, Glaucoma Eye
MicroPulse TLT - UK Study
This Prospective Interventional Study will assess the efficacy of MPTLT in the UK.
- Conditions
- Glaucoma, Glaucoma Eye, Glaucoma, Open-Angle, Glaucoma Secondary
- Trial name
- MPTLTUKS (NCT05593354)
- Testing
- Micropulse Transscleral laser therapy
- Volunteers
- 250 people
- Sponsor
- Imperial College Healthcare NHS Trust
Angle-closure Glaucoma
Travoprost 0.004% Versus Pilocarpine 1% in Patients With Chronic Angle Closure Glaucoma (CACG)
The purpose of this study is to demonstrate that the Intraocular Pressure (IOP) lowering efficacy of Travoprost Ophthalmic Solution 0.004% is superior to that of Pilocarpine 1% in patients with chronic angle-closure glaucoma…
- Trial name
- NCT00762645
- Testing
- Travoprost 0.004% (Travatan), Pilocarpine 1%
- Volunteers
- 30 people
- Sponsor
- Alcon Research
Glaucoma, Angle-closure
Immediate Anterior Chamber Paracentesis With A 30-Gauge Needle for Acute Primary Angle - Closure
This study was to evaluate the efficacy and safety of immediate anterior chamber paracentesis (ACP) with a 30-gauge needle as an initial treatment for acute primary angle closure (APAC).
- Trial name
- NCT01923454
- Testing
- Paracentesis, Acetazolamide, Peripheral iridotomy
- Where
- Thailand
- Volunteers
- 15 people
- Sponsor
- Siriraj Hospital
Primary Angle Closure Glaucoma
Trabeculectomy Versus Peripheral Iridectomy Plus Goniotomy in Advanced PACG
A multicenter, parallel, open, non-inferior randomized controlled trial is conducted to compare the effectiveness and safety of trabeculectomy and peripheral iridectomy plus goniotomy (TVG) in the treatment of advanced primary…
- Trial name
- TVG (NCT05163951)
- Testing
- Trabeculectomy, SPI+GSL+GT
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Sun Yat-sen University
Glaucoma
The Genetic Study of Primary Angle-Closure Glaucoma
The purpose of this study is to evaluate the possible candidate gene of Primary Angle-Closure Glaucoma.
- Trial name
- NCT00155857
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Glaucoma, Angle-Closure
Study of Brimonidine and Timolol Ophthalmic Solution With Latanoprost Compared With Latanoprost in Glaucoma Patients
This study will evaluate the safety and efficacy of patients switched from latanoprost monotherapy to a combination therapy of latanoprost with COMBIGAN® (brimonidine 0.2%/timolol 0.5% fixed combination ophthalmic solution) for…
- Trial name
- NCT01151904
- Testing
- brimonidine 0.2%/timolol 0.5% fixed combination ophthalmic solution, latanoprost
- Where
- Thailand
- Volunteers
- 17 people
- Sponsor
- Allergan
Glaucoma
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma
There is increasing evidence that there are genetic risk factors for several forms of glaucoma, such as glaucoma caused by pseudoexfoliation syndrome (PXF) ,primary angle closure glaucoma (PACG) and primary open-angle glaucoma…
- Trial name
- NCT03423758
- Testing
- Blood sample
- Where
- Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Primary Angle Closure Glaucoma
Comparison of Phaco Surgery With Goniosynechialysis Versus Trabeculectomy in Glaucoma Treatment
The goal of this clinical trial is to learn whether phacoemulsification combined with goniosynechialysis (Phaco-GSL) is as effective and safe as trabeculectomy in treating patients with primary angle-closure glaucoma.
- Trial name
- NCT06952153
- Testing
- Phacoemulsification with Goniosynechialysis, Trabeculectomy with 5FU
- Where
- Vietnam
- Volunteers
- 82 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City