Clinical trials: Glaucoma
Glaucoma, Pterygium
Ologen (OculusGen)-Glaucoma and Pterygium Historical Control Study in China Beijing Hospital
The purpose of this study is to determine whether the OculusGen Collagen Matrix is effective and safe to implant as an aid of glaucoma and pterygium surgeries.
- Trial name
- NCT00320762
- Testing
- OculusGen Biodegradable Collagen Matrix Implant
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Pro Top & Mediking Company Limited
Glaucoma
Supracapsular Ahmed Glaucoma Valve Plate Delivery Technique for Management of Encapsulated Bleb in Pediatric Patients
This study aims to assess the safety and efficacy of supracapsular Ahmed Glaucoma Valve plate delivery for management of encapsulated bleb in pediatric patients with failed Ahmed Glaucoma Valve.
- Trial name
- NCT04931290
- Testing
- Supracapsular Ahmed Glaucoma Valve plate delivery technique
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Mansoura University
Glaucoma
Glaucoma Evaluation With the P200TE
Images captured on the P200TE device on glaucoma patients
- Trial name
- NCT06305481
- Testing
- P200TE
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Optos, PLC
Glaucoma
Comparison of Optic Nerve Head and Retinal Nerve Fiber Layer Parameters Derived From Two Different Methods of Scan Alignment
This prospective, monocentric, non-invasive clinical study is designed to measure normal structural parameters of the optic nerve head, the peripapillary retinal nerve fiber layer, and the macula using the Heidelberg Spectralis…
- Trial name
- NCT02666144
- Testing
- Spectralis OCT
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
The Incidence and Risk Factors of Glaucoma After Congenital Cataract Surgery
Correlative Study on Incidence and Risk Factors of Glaucoma-related Adverse Event at Various Durations After Congenital Cataract Surgery
A retrospective chart review of 264 eyes from 177 patients was performed who underwent congenital cataract surgery before the age of 14 years.
- Trial name
- NCT04521907
- Where
- China
- Volunteers
- 177 people
- Sponsor
- Wenzhou Medical University
Glaucoma
Serum Citrate in Diagnosis and Follow-up for Glaucoma
Glaucoma might be a mitochondria associated disease. Since citrate is a major component in mitochondrial metabolism its determination in blood might serve as a biomarker.
- Trial name
- NCT00804063
- Testing
- drawing blood sample
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Glaucoma, Open-Angle, Ocular Hypertension
Performance of the Travoprost Intraocular Implant
To evaluate the performance of the Travoprost Intracameral Implant by determining residual drug in explanted implants of the Travoprost Intracameral Implant and by determining aqueous humor concentrations of travoprost free acid…
- Trial name
- NCT06582732
- Testing
- Travoprost Intracameral Implant exchanged at Month 12, Travoprost Intracameral Implant exchanged at Month 3, Travoprost Intracameral Implant exchanged at Month 6
- Where
- Armenia
- Volunteers
- 210 people
- Sponsor
- Glaukos Corporation
Glaucoma
Comparison Between Handheld Rebound Tonometer and Applanation Tonometer in IOP Measurement in Paediatric Glaucomas
To compare the accuracy between handheld rebound tonometer \& applanation tonometer in IOP measurement in pediatric glaucoma cases
- Trial name
- NCT06766799
- Testing
- Rebound and Applanation Tonometer
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Sohag University
Assess Eye Measurements in Patients Having Retina Pathology or Glaucoma
Evaluation of OCT Measurements
The purpose of the study is to repeatability, reproducibility and agreement of eye measurements in retina and glaucoma patients.
- Trial name
- NCT01806402
- Where
- 3 sites in United States
- Volunteers
- 135 people
- Sponsor
- Optovue
Glaucoma
Phase 2 Study of BL1107 Eye Drops vs. Timolol in Adults With Primary Open Angle Glaucoma or Ocular Hypertension
Phase 2 Study of BL1107 Eye Drops vs. Timolol in Adults with Primary Open Angle Glaucoma or Ocular Hypertension
- Trial name
- NCT07168902
- Testing
- BL1107 Low dose, BL1107 High dose, Timolol maleate 0.5%
- Where
- 14 sites in United States
- Volunteers
- 252 people
- Sponsor
- Bausch & Lomb Incorporated
Glaucoma
Spectralis OCT Repeatability and Reproducibility Study
This single-center, prospective, interventional clinical study is conducted to evaluate the repeatability and reproducibility of structural parameters of the optic nerve head, the peripapillary retinal nerve fiber layer, and the…
- Trial name
- S-2013-1 (NCT02209077)
- Testing
- OCT performed to collect data from the back of the eye
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Glaucoma
Evaluate the Safety and Effectiveness of iSTAR Medical's MINIject™ Implant for Lowering Intraocular Pressure (IOP) in Subjects With Primary Open-angle Glaucoma.
Evaluate the safety and effectiveness of iSTAR Medical's MINIject™ implant for lowering intraocular pressure (IOP) in subjects with primary open-angle glaucoma.
- Trial name
- STAR-V (NCT05024695)
- Testing
- MINIject™ Implant
- Where
- 37 sites in United States, Canada and 2 more
- Volunteers
- 975 people
- Sponsor
- iSTAR Medical
Glaucoma
Altered Non-Visual Photoreception in Patients With Glaucoma: Impacts on Sleep, Alertness, Mood, and Cognition
The goal of this study is to understand how light sensitivity in the eye affects sleep, mood, alertness, and cognition in adults with glaucoma compared to healthy individuals aged 45-75 years.
- Trial name
- EyeQ (NCT07364929)
- Testing
- Full-spectrum light exposure, Standard indoor light exposure (Control)
- Where
- 2 sites in Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Glaucoma, Eye Diseases
The Role of Transscleral Cyclophotocoagulation in Patients Undergoing a Boston Keratoprosthesis
The Boston keratoprosthesis (KPro) is a special plastic device that is used to replace a sick cornea (transparent part of the eye, in front of the iris) in order to restore vision in patients who have failed traditional corneal…
- Conditions
- Glaucoma, Eye Diseases, Cornea Disease
- Trial name
- NCT04232982
- Testing
- Transscleral cyclphophotocoagulation using the Micropulse system ( IRIDEX IQ810 Laser systems, Mountain View, CA)., G-Probe transscleral cyclphophotocoagulation (Iris Medical Instruments, Montain View, CA)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Glaucoma, Ocular Hypertension
Patient Preference Study
In this randomized crossover study, patients will receive a single drop of two test articles and assess comfort.
- Trial name
- NCT00576342
- Testing
- AL-3862+timolol ophthalmic suspension, Dorzolamide+timolol ophthalmic solution
- Volunteers
- 129 people
- Sponsor
- Alcon Research
Glaucoma
Awareness and Perception of Glaucoma Among Patients Attending Ophthalmology OPD in a Tertiary Care Hospital.
Glaucoma is often called the "silent thief of vision" because it can slowly damage the optic nerve and cause permanent blindness if it is not found and treated early.
- Trial name
- NCT07153588
- Testing
- Level of awareness
- Where
- Pakistan
- Volunteers
- 379 people, healthy volunteers welcome
- Sponsor
- Bacha Khan Medical College
Glaucoma
Open Label Extension of LipoLat-CS202
This is an open-label, observational extension of patients who received POLAT-001 in LipoLat-CS202.
- Trial name
- NCT02599688
- Testing
- Observation only
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Peregrine Ophthalmic
Open Angle Glaucoma, Ocular Hypertension
Pilocarpine After Combined Cataract/Trabectome Surgery
Combined cataract + trabectome surgery is a surgery designed to help lower the intraocular pressure (pressure in the eye) and hopefully reduce the need for topical drops, progression of glaucoma, and/or further glaucoma…
- Trial name
- PACCT (NCT04005079)
- Testing
- Pilocarpine, Ofloxacin, Prednisolone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Glaucoma
Goldmann Applanation Tonometry, Dynamic Contour Tonometry, and Corvis ST Tonometer
The study is investigating Intra ocular pressure (IOP) by Goldmann Applanation Tonometry, Dynamic Contour Tonometry, and the Corvis ST tonometer.
- Trial name
- NCT02624427
- Testing
- Measurement of intraocular pressure (IOP)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Glaucoma
CLARITY Imaging Study
OCT image quality is necessary to provide accurate diagnostic information to ophthalmologists. The increasing resolution of imaging techniques will require ever more high standards of optical transmission through the cornea and…
- Trial name
- CLARITY (NCT03758859)
- Testing
- sodium hyaluronate eyedrops
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Imperial College London