Clinical trials: Glaucoma Diagnosis
Glaucoma, Angle-Closure
AS-OCT Evaluation of Iridocorneal Angle of Patients of Angle Closure Glaucoma After Phacoemulsification
Evaluation of the effect of phacoemulsification and YAG Laser peripheral iridotomy on the anterior chamber angle anatomic parameters in PACG eyes, using anterior segment optical coherence tomography (SS ASOCT) device
- Trial name
- NCT05332665
- Testing
- AS-OCT, YAG laser PI
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Minia University
Glaucoma
Evaluation of Blood Flow Characteristics in Glaucoma Using Optical Coherence Tomography Angiography (OCT-A).
The investigators aim to evaluate the efficacy of the new Optical Coherence Tomography based Angiography (OCT-A) softwares in the diagnosis and management of glaucoma.
- Trial name
- NCT02757677
- Testing
- Optical Coherence Tomography based Angiography
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Swiss Vision Network
Open Angle Glaucoma, Ocular Hypertension
A Long Term Study of STN1012600 in Subjects With Open Angle Glaucoma or Ocular Hypertension
To evaluate safety and the ocular hypotensive effect of STN1012600 ophthalmic solution 0.002% alone or in combination with Timolol ophthalmic solution 0.5% for 52 weeks in subjects with open angle glaucoma or ocular hypertension.
- Trial name
- NCT05503901
- Testing
- STN1012600 ophthalmic solution 0.002%, STN1012600 ophthalmic solution 0.002% and Timolol ophthalmic solution 0.5%
- Where
- 18 sites in Japan
- Volunteers
- 131 people
- Sponsor
- Santen Pharmaceutical Co., Ltd.
Glaucoma, Open-Angle
Early Evaluation of the Beacon Aqueous Microshunt in Patients Refractory to Drug Therapy in the European Union
This is prospective, non-randomized, single-arm study to assess the safety and effectiveness of lowering intraocular pressure with the Beacon Aqueous Microshunt. A total of 65 subjects will be enrolled at five centers.
- Trial name
- EARLY BIRD EU (NCT03634319)
- Testing
- Beacon Aqueous Microshunt
- Where
- 2 sites in Germany
- Volunteers
- 10 people
- Sponsor
- MicroOptx
Glaucoma, Cataract
Evaluation of Microinvasive Glaucoma Surgery: MINIject® Versus Hydrus® Microstent in Combination With Cataract Surgery
The study aims to investigate postoperative outcomes after two different MIGS implants (MINIject or Hydrus) in combination with cataract surgery for patients with glaucoma.
- Trial name
- MINHY (NCT06844292)
- Testing
- MINIject with Cataract Surgery, Hydrus Microstent with Cataract Surgery
- Where
- Austria
- Volunteers
- 152 people
- Sponsor
- Medical University of Graz
Normal Tension Glaucoma
R&D of Non-invasive Innovative Intracranial Waves Monitoring System for Diagnostics and Treatment Monitoring of Patients with Normal Tension Glaucoma
Assessment and monitoring of intracranial pressure (ICP) changes are important in the management of cerebral pathologies. In the eye, ICP increase and decrease both correlate with optic neuropathies, the former because of…
- Trial name
- NCT06443411
- Testing
- Monitoring of cerebral hemodynamics
- Where
- Lithuania
- Volunteers
- 156 people
- Sponsor
- Lithuanian University of Health Sciences
Retina Disease, Glaucoma
Multi-modal Intelligent Diagnosis System for Multiple Ophthalmic Diseases
Aiming at the problems of low image reading efficiency, crowded medical resources and fragmented cross-modal information of ophthalmic OCT and OCTA, a multimodal large model diagnostic framework for various diseases such as…
- Trial name
- NCT07143851
- Testing
- Not applicable- observational study
- Volunteers
- 5,000 people
- Sponsor
- Beijing Hospital
Glaucoma
Timing of Treatment Completion in Staged Selective Laser Trabeculoplasty (SLT): Early vs. Late Completion
This study will evaluate the effect of the timing of treatment completion in two-staged selective laser trabeculoplasty therapy on intraocular pressure lowering effect.
- Trial name
- NCT00551395
- Testing
- selective laser trabeculoplasty - early completion, Selective laser trabeculoplasty - late completion
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Queen's University
Glaucoma, Ocular Hypertension
Latanoprost Preserved Versus Unpreserved: Effect on Tear Film Thickness as Measured With OCT
Topical antihypertensive eye drops are a key element of modern antiglaucoma treatment. Most of these eye drops contain preservatives to allow for the use of multi-dose containers.
- Trial name
- NCT02585375
- Testing
- Preservative-free latanoprost 50µg/ml, Preserved latanoprost 0.005%
- Where
- Austria
- Volunteers
- 70 people
- Sponsor
- Medical University of Vienna
Glaucoma, Open-Angle
Travoprost Intraocular Implant + iStent Infinite
Adult subjects with elevated intraocular pressure will be randomized to receive iStent infinite trabecular bypass system plus a travoprost intraocular implant or receive a sham procedure plus a travoprost intraocular implant and…
- Trial name
- NCT06066645
- Testing
- Travoprost Intraocular Implant, iStent infinite
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Glaukos Corporation
Glaucoma, Ocular Hypertension
Safety and Efficacy of Brinzolamide Dosed TID With Dorzolamide Dosed TID in Reducing Intraocular Pressure in Patients With Open Angle Glaucoma or Ocular Hypertension
Safety and Efficacy of Brinzolamide Dosed TID With Dorzolamide Dosed TID in Reducing Intraocular Pressure in Patients With Open Angle Glaucoma or Ocular Hypertension
- Trial name
- NCT00761995
- Testing
- Azopt, Cosopt
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Alcon Research
Glaucoma, Glaucoma, Open-Angle
Clinical Study of Glaukos® Trabecular Micro-Bypass System Model iS3 Infinite Vs. Competitor
A study of the iStent Infinite product in the treatment of open-angle glaucoma vs competitor
- Trial name
- NCT05127551
- Testing
- iStent Infinite, Competitor Device
- Where
- Canada
- Volunteers
- 179 people
- Sponsor
- Glaukos Corporation
Glaucoma
Patient Performance on Virtual Reality Visual Field Devices as Compared to Standard of Care
The purpose of this research is to study the effectiveness and patient experience when measuring visual fields using virtual reality goggles.
- Trial name
- NCT04994457
- Testing
- Virtual Reality Visual Field, Standard Automated Perimetry
- Where
- United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- University of Miami
Glaucoma, Ocular Hypertension
Efficacy and Safety Assessment of T4032 (Unpreserved Bimatoprost 0.01%) Versus Lumigan® 0.01% in Ocular Hypertensive or Glaucomatous Patients
The main study purpose is to demonstrate the non-inferiority of T4032 compared to Lumigan® 0.01% in terms of efficacy.
- Trial name
- NCT05397600
- Testing
- Bimatoprost Ophthalmic
- Where
- 64 sites in United States, Canada and 1 more
- Volunteers
- 684 people
- Sponsor
- Laboratoires Thea
Glaucoma, Diabetic Retinopathy
Providing Financial Incentives to Improve Adherence to Referral Eye Care Visits
Glaucoma is a blinding eye disease increasingly common in older adults, particularly in African Americans, and often diagnosed late in the disease course.
- Conditions
- Glaucoma, Diabetic Retinopathy, Refractive Errors, Cataract
- Trial name
- AL-SIGHT (NCT04328207)
- Testing
- No Financial Incentive, Financial Incentive
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Primary Open-angle Glaucoma
Impact of Glaucoma and Visual Field Loss on Life Space
Mobility refers to a person's purposeful movement through the environment from one place to another and can be conceptualized as a continuum from bed bound (immobility) on one extreme to making excursions to distant locations on…
- Trial name
- NCT03673644
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Alabama at Birmingham
Primary Open Angle Glaucoma, Ocular Hypertension
A Phase 2, Dose Finding Study of PF-03187207 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension.
To investigate dose response, safety and efficacy of PF-03187207 in patients with primary open-angle glaucoma or ocular hypertension
- Trial name
- NCT00595101
- Testing
- PF-03187207, Latanoprost 0.005%, PF-03187207 Vehicle
- Where
- 13 sites in Japan
- Volunteers
- 117 people
- Sponsor
- Bausch & Lomb Incorporated
Glaucoma, Glaucoma, Open-Angle
Treatment Outcomes of a Novel Glaucoma Tube Shunt Implant for Intraocular Pressure Control in Eyes With Refractory Glaucoma
The aim of this study is to determine the effectiveness of lowering intraocular pressure and safety profile of the Paul Glaucoma Implant (Advanced Ophthalmic Innovations, Singapore).
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Surgery, Intraocular Pressure
- Trial name
- NCT04297930
- Testing
- Paul Glaucoma Implant Surgery
- Where
- Singapore
- Volunteers
- 82 people
- Sponsor
- National University Hospital, Singapore
Glaucoma, Open-Angle
Negative Pressure Applied by the Equinox MPD for Severe Open Angle Glaucoma
This is a prospective, non-significant risk, controlled, randomized, multi-center, masked, feasibility study to evaluate the safety and IOP-lowering effectiveness of negative pressure application (via the Mercury MPD) for…
- Trial name
- NCT04632329
- Testing
- Negative Pressure Treatment via the Mercury Multi-Pressure Dial
- Where
- 3 sites in United States
- Volunteers
- 64 people
- Sponsor
- Equinox
Open Angle Glaucoma
Standalone OMNI Surgical System for Open-angle Glaucoma
The emergence of minimally invasive glaucoma surgeries (MIGS) has seen a variety of potential innovative surgical alternatives to help better control intraocular pressure (IOP).
- Trial name
- OMNIgl (NCT04427995)
- Testing
- OMNI surgical system
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Iqbal Ahmed
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