Clinical trials: Glaucoma Diagnosis
Glaucoma, Open-Angle
Study of OMNI Surgical System and iStent for Eyes With OAG (Trident)
First, to compare safety and effectiveness outcomes for canaloplasty and trabeculotomy using the OMNI Surgical System to implantation of the iStent inject in lowering intraocular pressure (IOP) in pseudophakic eyes with open…
- Trial name
- NCT04658095
- Testing
- Canaloplasty and trabeculotomy with the OMNI system., iStent inject, Canaloplasty
- Where
- 5 sites in Germany, Spain and 1 more
- Volunteers
- 10 people
- Sponsor
- Sight Sciences, Inc.
Primary Open Angle Glaucoma (POAG), Juvenile Open Angle Glaucoma
Testing a Reading Module to Improve Reading Skills and Quality of Life in Glaucoma Patients
The goal of this interventional study is to test the effectiveness of reading rehabilitation module towards reading speed and error, and quality of life in glaucoma patients.The main questions it aims to answer are: 1.
- Conditions
- Primary Open Angle Glaucoma (POAG), Juvenile Open Angle Glaucoma, Normotensive Glaucoma, Primary Angle Closure Glaucoma
- Trial name
- NCT07741812
- Testing
- Reading Rehabilitation Module
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- Universiti Sains Malaysia
Glaucoma, Acupuncture
Clinical Evaluation of Acupuncture in Treating Glaucoma
The present study predicts that acupuncture or electroacupuncture can reduce intraocular pressure and also can improve quality of life in patients with glaucoma.
- Trial name
- NCT04157530
- Testing
- wang-bu-liu-xing, acupuncture, Electroacupuncture
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- China Medical University Hospital
Glaucoma
OculusGen-Glaucoma Historical Control Study in Taiwan
The purpose of this study is to determine whether the OculusGen Collagen Matrix are effective and safe to implant as an aid of glaucoma surgery.
- Trial name
- NCT00406822
- Testing
- OculusGen Biodegradable Collagen Matrix Implant
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Pro Top & Mediking Company Limited
Glaucoma, Ocular Hypertension
Effects of Travatan Z and Xalatan on Ocular Surface Health
The purpose of this randomized, double-masked, parallel-group, multicenter study is to evaluate ocular surface effects after the administration of travoprost with SofZia® preservative system or Xalatan once daily for 12 weeks.
- Trial name
- NCT00708422
- Testing
- Travoprost ophthalmic solution 0.004% with SofZia® preservative system (TRAVATAN Z®), Latanoprost ophthalmic solution 0.005% (XALATAN®)
- Volunteers
- 231 people
- Sponsor
- Alcon Research
Glaucomas, Pterygium
Ologen (OculusGen)-Glaucoma and Pterygium Historical Control Study in China Zhong-Shan Hospital
The purpose of this study is to determine whether the OculusGen Collagen Matrix are effective and safe to implant as an aid of glaucoma surgery.
- Trial name
- NCT00320957
- Testing
- OculusGen Biodegradable Collagen Matrix Implant
- Where
- China
- Volunteers
- 61 people
- Sponsor
- Pro Top & Mediking Company Limited
Glaucoma, Open-Angle, Suprachoroidal Space
Safety and Efficacy of Suprachoroidal Tube Shunt in Patients With Primary Open and Pseudoexfoliation Glaucomas
To assess safety and efficacy of a novel suprachoroidal silicone tube (SST) shunt for the treatment of primary open angle and exfoliative glaucomas.
- Conditions
- Glaucoma, Open-Angle, Suprachoroidal Space, Pseudo Exfoliation Syndrome
- Trial name
- NCT06154330
- Where
- Georgia
- Volunteers
- 91 people
- Sponsor
- Davinci LTD
Kidney Diseases, Diastolic Heart Failure
Investigating Multimodally Endothelial Dysfunction in Ocular and Systemic Disease
To explore the distribution of retinal vasculature parameters in patients with different subtypes of cardiovascular and ocular disease.
- Conditions
- Kidney Diseases, Diastolic Heart Failure, Small Vessel Disease, Glaucoma
- Trial name
- NCT06485128
- Testing
- Optical coherence tomography(-angiography) OCT(A), Fundus pictures, DVA 3.0
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Glaucoma, Ocular Hypertension
Safety and Efficacy of Triple Combination Therapy With Dorzolamide Hydrochloride / Brimonidine Tartrate / Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
This study will investigate the safety and efficacy of Triple Combination Therapy with dorzolamide hydrochloride/brimonidine tartrate/timolol ophthalmic solution in patients with glaucoma or ocular hypertension who have elevated…
- Trial name
- NCT01284166
- Testing
- dorzolamide hydrochloride 2.0%/brimonidine tartrate 0.2%/timolol 0.5% ophthalmic solution
- Sponsor
- Allergan
Glaucoma, AMD
A Real-World Study of Interventional Clinical Outcomes in Patients With Open Angle Glaucoma and Other Chronic Eye Diseases
This is a real world investigation of patient who have undergone treatments for chronic eye conditions such as glaucoma and AMD.
- Conditions
- Glaucoma, AMD, Diabetic Retinopathy (DR)
- Trial name
- NCT07216677
- Testing
- Chronic Disease Intervention CDI
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Interstat LLC
Glaucoma
Intraocular Pressure (IOP) Lowering Effect of Selective Laser Trabeculoplasty Versus Prostaglandin Analogues in Angle Closure Glaucoma
Glaucoma affects 66 million people worldwide and is the leading cause of irreversible blindness, and Primary angle-closure glaucoma (PACG) is a major form of glaucoma in Asia.
- Trial name
- NCT01004900
- Testing
- Selective Laser Trabeculoplasty, Travoprost/ Timolol/ Azopt/ Brimonidine
- Where
- Singapore
- Volunteers
- 90 people
- Sponsor
- Singapore Eye Research Institute
Primary Open-angle Glaucoma
Decorin in Sub Scleral Trabeculectomy
This is a prospective, single-center, interventional, randomized controlled study comparing Decorin as antifibrotic agent in sub scleral trabeculectomy versus Mitomycin.
- Trial name
- NCT03924544
- Testing
- Decorin, Mitomycin c
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Primary Angle-Closure Glaucoma
The Multi-Omics Analysis of Lens Zonule Relaxation in The PACG Pathogenesis
Compared with primary angle-closure glaucoma (PACG) patients without zonular laxity and the control group, there are differentially expressed molecules in PACG patients with zonular laxity, and a potential mechanistic network can…
- Trial name
- NCT07539675
- Testing
- No Additional Experimental Intervention
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Zhongnan Hospital
Glaucoma
Steroids and/ or Non-steroidal Anti-inflammatory Drugs in the Postoperative Regime After Trabeculectomy.
PURPOSE: Glaucoma is the leading cause of non-curable blindness globally. Patients with glaucoma will get a gradual narrowing of the visual fields caused by compression at the optic nerve head due to increased intraocular…
- Trial name
- SNAP (NCT04054830)
- Testing
- Voltaren Ophtha 1 mg/ml, GSK, Monopex 1 mg/ml, Théa
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Glaucoma
Frequency Doubling Technology (FDT) Mobile Visual Field Testing
This is a single center, prospective study to evaluate the efficacy and reproducibility of frequency doubling technology (FDT)-based visual field devices compared to conventional Humphrey Visual Field (HVF) perimetry.
- Trial name
- NCT02862158
- Testing
- FDT visual field, Standard HVF
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Miami
Open Angle Glaucoma
Impact of a Tolerability Switch to Dorzolamide/Timolol Preservative-free Fixed Combination on Ocular Surface Symptoms
This study aims at validating in real-life clinical practice and using the self-reported Glaucoma Symptom Scale (GSS) questionnaire, the impact of a switch to preservative-free dorzolamide/timolol fixed combination (DTFC) in…
- Trial name
- NCT01923714
- Where
- Belgium
- Volunteers
- 103 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cataract
Symfony Intraocular Lens Retrospective Chart Review
Retrospective chart review of patients with pre-existing ocular pathology who underwent cataract surgery with implantation of the Symfony IOL.
- Trial name
- NCT05111106
- Testing
- Symfony IOL
- Volunteers
- 463 people
- Sponsor
- Austin Eye
Glaucoma
Cyclophotocoagulation in Glaucoma
Transscleral cyclophotocoagulation of the ciliary body is an effective technique to reduce intraocular pressure in case of glaucoma.
- Trial name
- NCT02875158
- Testing
- Cyclophotocoagulation protocol, Conventional cyclophotocoagulation, Modified cyclophotocoagulation
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Glaucoma and Ocular Hypertension
Prospective,Randomized,Controlled Study to Assess Efficacy,Safety, and Tolerability of SLT vs. PLT in Patients With POAG
A prospective, randomized, controlled study to assess efficacy, safety, and tolerability of selective laser trabeculoplasty vs. pattern laser trabeculoplasty in patients with open-angle glaucoma.
- Trial name
- NCT02231515
- Testing
- Selective laser trabeculoplasty (SLT), Pattern laser trabeculoplasty (PLT)
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- University Hospital, Geneva
Glaucoma, Open Angle or Ocular Hypertension
Therapeutic Equivalence Study of Generic Brinzolamide vs Azopt
The main purpose of this prospective study is to demonstrate the therapeutic equivalence of topical brinzolamide dosed three times daily compared with AzoptTM (brinzolamide ophthalmic suspension 1%) dosed three times daily in IOP…
- Trial name
- NCT01722604
- Testing
- brinzolamide 1% ophthalmic suspension, Azopt 1%
- Where
- United States
- Volunteers
- 258 people
- Sponsor
- Bausch & Lomb Incorporated
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