Clinical trials: Glaucoma Diagnosis
Glaucoma, Primary Open Angle Glaucoma
Tafluprost Preservative Free Switch Study
This study is conducted to document the effect of switching from preserved prostaglandin analogues monotherapy to preservative free tafluprost 0.0015%. The endpoints analyzed are side effect improvement in these patients.
- Conditions
- Glaucoma, Primary Open Angle Glaucoma, Ocular Hypertension
- Trial name
- NCT04654611
- Testing
- preservative free tafluprost 0.0015%
- Where
- Malaysia
- Volunteers
- 28 people
- Sponsor
- Tun Hussein Onn National Eye Hospital
Glaucoma
Effect of Mitomycin-C on the Outcomes of Patients Receiving Ahmed Glaucoma Valve Implantation Surgery
The goal of this clinical trial is to determine if the intraoperative application of Mitomycin-C can enhance the outcomes of Ahmed Glaucoma Valve (AGV) implantation in treating refractory glaucoma.
- Trial name
- MMC (NCT06680245)
- Testing
- Mitomycin c
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Glaucoma
Micro vs. Standard Trabeculectomy Study
The purpose of this study is to determine the reduction in intraocular pressure and cumulative incidence of complications between the standard and micro trabeculectomy surgeries 3 months after surgery.
- Trial name
- NCT02598765
- Testing
- Standard Trabeculectomy, Microtrabeculectomy
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Ophthalmopathy, Glaucoma
Phaco-Trabeculotomy Vs Phaco-Trabeculectomy
A prospective, randomized comparative study on adult patients with synechial angle closure glaucoma.
- Conditions
- Ophthalmopathy, Glaucoma, Glaucoma, Angle-Closure
- Trial name
- PDT vs PT (NCT04683055)
- Testing
- Phacoemulsification combined with trabeculectomy, Phacoemulsificaiton combined with ab-externo trabeculotomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Primary Open Angle Glaucoma
Visco-Circumferential-Suture-Trabeculotomy Versus Rigid Probe Viscotrabeculotomy in Primary Open Angle Glaucoma
Visco-Circumferential-Suture-Trabeculotomy versus Rigid probe Viscotrabeculotomy in Primary Open Angle Glaucoma.
- Trial name
- NCT05666440
- Testing
- Visco-Circumferential-Suture-Trabeculotomy in Primary Open Angle Glaucoma., Rigid probe Viscotrabeculotomy in Primary Open Angle Glaucoma.
- Volunteers
- 166 people
- Sponsor
- Mansoura University
Glaucoma Eye
The Value of Visual Field Examination in Driving Licence.
The aim of the study is to identify clinical criteria, easily achievable with patient's follow-up tests, which can identify individuals at increased risk of being unfit to drive.
- Trial name
- NCT04671550
- Testing
- questionnaire
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Università degli Studi dell'Insubria
Primary Open Angle Glaucoma, Ocular Hypertension
Study of the Intraocular Pressure (IOP)-Lowering Efficacy of Azopt 1.0% Compared to Timolol 0.5% in Patients With Glaucoma or Ocular Hypertension
This is a multiple-dose study of the IOP-lowering efficacy of Azopt (brinzolamide) 1.0% compared to timolol 0.5% when added to a prostaglandin analogue (PGA) as adjunctive therapy over a 24 hour period in patients with glaucoma…
- Trial name
- NCT00300079
- Testing
- brinzolamide 1.0%
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Alcon Research
Primary Open - Angle Glaucoma (POAG), Ocular Hypertension (OHT)
A Phase 2a Study Comparing the Efficacy, Safety and Tolerability of Pregabalin Eye Drops Comparing With Timolol Eye Drops in Adults With Glaucoma or High Eye Pressure.
This study is evaluating a new eye drop containing pregabalin (TB0001) as a potential treatment for people with primary open-angle glaucoma or ocular hypertension.
- Trial name
- NCT07913074
- Testing
- Arm 1: TB0001 ophthalmic solution 0.9%, Arm 2: TB0001 ophthalmic solution 1.2%, TB0001 ophthalmic solution 1.5%
- Where
- 3 sites in United States
- Volunteers
- 96 people
- Sponsor
- Tavo Biotherapeutics
Glaucoma
Human Optokinetic Contrast Device (HOCD) to Measure Visual Function and Identify Patients With and Without Glaucoma
The purpose of this study is to determine if an optokinetic contrast detection device is sufficient to measure contrast sensitivity and to distinguish between patients with and without glaucoma.
- Trial name
- HOCD (NCT02014597)
- Testing
- HOCD
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Benjamin Frankfort, MD, PhD
Diabetes Mellitus, Glaucoma
Smartphone Screening for Eye Diseases
To validate new screening instruments for eye disease, increase eye care access in underserved communities, and provide a scientifically implemented method to set up programs for eye disease screening.
- Conditions
- Diabetes Mellitus, Glaucoma, Age Related Macular Degeneration, ROP
- Trial name
- NCT03076697
- Testing
- Fundus photography
- Volunteers
- 472 people
- Sponsor
- University of Michigan
Glaucoma, Open-Angle
Evaluating Home Testing Devices for the Management of Glaucoma
With the advancement in technology we have the opportunity of performing the glaucoma testing at home to monitor the disease. The purpose of this study is evaluating the feasibility and patient acceptance of home testing with…
- Trial name
- NCT05325996
- Testing
- Standard Automatic Perimetry Humphrey Field Analyzer, visuALL H, iCare Home Tonometer
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Wills Eye
Open-Angle Glaucoma, Ocular Hypertension
Long-term Safety and Efficacy Extension Trial of Bimatoprost SR
This study will evaluate the long-term safety and efficacy of Bimatoprost Sustained Release (SR) in patients with open-angle glaucoma or ocular hypertension who completed 1 of the 4 Phase 3 Bimatoprost SR studies (192024-091…
- Trial name
- MAIA (NCT03891446)
- Testing
- Bimatoprost SR, Standard of Care
- Where
- 124 sites in United States, Argentina and 24 more
- Volunteers
- 455 people
- Sponsor
- AbbVie
Glaucoma, Open-Angle, Ocular Hypertension
Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.
This is a randomized, double-blind, two-treatment, single-period, parallel design, multiple dose at multiple clinical trial sites designed to demonstrate bioequivalence with clinical endpoint in subjects with chronic open-angle…
- Trial name
- NCT05401357
- Testing
- Test - Bimatoprost 0.01% Ophthalmic Solution, Reference - LUMIGAN® (Bimatoprost 0.01% Ophthalmic Solution)
- Where
- 9 sites in United States
- Volunteers
- 168 people
- Sponsor
- Amneal Pharmaceuticals, LLC
Glaucoma
NSAID vs Steroid in Trabeculectomy Wound Management
This study will examine the efficacy of steroid vs NSAID treatment in relation to trabeculectomy wound management. Eligible study participants will be randomized to receive either steroid or NSAID topical treatment one week…
- Trial name
- NCT03751059
- Testing
- Bromfenac 0.07% Oph Susp, Dexamethasone
- Volunteers
- 150 people
- Sponsor
- Cindy Hutnik
Primary Open-angle Glaucoma
Safety and Tolerability of a Timolol Releasing Intraocular Implant in Subjects With Primary Open-angle Glaucoma
The purpose of this study is to test a new method to deliver an approved medicine called Timolol in the eye of participants with glaucoma and pseudophakia (currently present or to be performed during the concomitant implantation…
- Trial name
- NCT06321562
- Testing
- TimoD implant, Injector system
- Where
- 5 sites in Germany
- Volunteers
- 1 people
- Sponsor
- EyeD Pharma
Glaucoma
Impact of an Educational Video on Satisfaction After Glaucoma Surgery
Overall Objective: This study will assess whether an educational video is effective in increasing patient satisfaction with glaucoma surgery. 1.
- Trial name
- NCT03958929
- Testing
- Educational Video
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Sun Yat-sen University
Primary Open Angle Glaucoma (POAG), Ocular Hypertension (OH)
A Study to Evaluate Efficacy and Safety of YSBP Compared to Lumigan in Patients With Glaucoma or Ocular Hypertension
This study is to establish non-inferiority of a preservative free formulation of Bimatoprost ophthalmic solution 0.01% (YSBP) of YS Life Science Co., Ltd.
- Trial name
- NCT07661329
- Testing
- Bimatoprost ophthalmic solution 0.01% YSBP, bimatoprost ophthalmic solution 0.01% (Lumigan®)
- Where
- 22 sites in United States, India
- Volunteers
- 600 people
- Sponsor
- YS Life Science Co., Ltd.
Open Angle Glaucoma, Ocular Hypertension
Efficacy and Safety of SPARC0912 and Reference0912 in Open Angle Glaucoma or Ocular Hypertension
A single-blind , 12-week, parallel group clinical study is planned to evaluate the efficacy and safety of SPARC0912 and Reference0912.
- Trial name
- NCT00947661
- Testing
- SPARC0912, Reference0912
- Where
- United States
- Volunteers
- 578 people
- Sponsor
- Sun Pharma Advanced Research Company Limited
Glaucoma
Supracapsular Ahmed Glaucoma Valve Plate Delivery Technique for Management of Encapsulated Bleb in Pediatric Patients
This study aims to assess the safety and efficacy of supracapsular Ahmed Glaucoma Valve plate delivery for management of encapsulated bleb in pediatric patients with failed Ahmed Glaucoma Valve.
- Trial name
- NCT04931290
- Testing
- Supracapsular Ahmed Glaucoma Valve plate delivery technique
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Mansoura University
Open Angle Glaucoma, Ocular Hypertension
24-hour Efficacy of AR-12286
An open-label, non-comparative, pilot evaluation of the 24-hour ocular hypotensive efficacy of AR-12286 in patients with open-angle glaucoma or ocular hypertension
- Trial name
- NCT01330979
- Testing
- AR-12286 0.5% Ophthalmic Solution
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Aerie Pharmaceuticals
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