Clinical trials: Glaucoma Diagnosis
Blind Painful Eye, Refractory Glaucoma
Use of Intravitreal Triamcinolone and Retrobulbar Chlorpromazine as Alternatives to the Management of Painful Blind Eye
The purpose of this study is to evaluate the efficacy of intravitreal triamcinolone and retrobulbar chlorpromazine as alternatives in the management of ocular pain in blind eyes.
- Conditions
- Blind Painful Eye, Refractory Glaucoma, Control of Pain Through Drug Injection
- Trial name
- NCT01404364
- Testing
- Triamcinolone, Chlorpromazine
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Hospital Governador Celso Ramos
Glaucoma
An App-based Instructional Platform to Improve Eye Drop Recall
The goal of this interventional study is to assess whether an in-office, language-concordant instructional app improves drop regimen recall in a population of glaucoma patients who are on multi-drop regimens.
- Trial name
- NCT06045390
- Testing
- App
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Glaucoma
Zhongshan Iridocorneal Endothelial Syndrome Study (ICEs)
This is a multi-center study to report the demographic profile, clinical features, and management in patients with Iridocorneal endothelial (ICE) syndrome in China.
- Trial name
- NCT03270761
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Sun Yat-sen University
Glaucoma
Analysis of Clinical Profiles of Chinese Patients With Normal Tension Glaucoma
To obtain demographic and baseline ophthalmic parameters (such as Intraocular Pressure profiles, disc morphological characteristics, central corneal thickness, peripapillary retinal nerve fibre layer thickness and its serial…
- Trial name
- NCT00321386
- Where
- 2 sites in Hong Kong
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Glaucoma
Effects of Anti-Glaucoma Medications on the Ocular Surface
The purpose of the study is to compare the efficacy of FDA-approved Travoprost (Travatan Z) and Latanoprost (Xalatan)as anti-glaucoma treatment.
- Trial name
- BAK (NCT01315574)
- Testing
- Travoprost, Latanoprost
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Primary Open Angle Glaucoma
Post Market Study of the InnFocus MicroShunt
Prospective, multicentric, single arm post market study to gather safety and effectiveness data on the CE Marked InnFocus MicroShunt (MIDI Arrow) device in primary open angle glaucoma patients
- Trial name
- NCT02177123
- Testing
- InnFocus MicroShunt implantation
- Where
- 6 sites in France, Netherlands and 2 more
- Volunteers
- 107 people
- Sponsor
- InnFocus Inc.
Open Angle Glaucoma or Ocular Hypertension
A Phase III Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Compared With Latanoprost Ophthalmic Solution in Subjects With OAG or OHT
The purpose of this study is to investigate the intraocular pressure-lowering effect and the safety of DE-117 ophthalmic solution compared with Latanoprost ophthalmic solution in subjects with open angle glaucoma or ocular…
- Trial name
- NCT02981446
- Testing
- DE-117, Latanoprost ophthalmic solution
- Where
- Singapore
- Volunteers
- 370 people
- Sponsor
- Santen Pharmaceutical Co., Ltd.
Glaucoma
Minimally Invasive Micro Sclerostomy: Safety and Preliminary Performance Study
Eligible Glaucoma patients will undergo pre-surgery examination including: medicines list, blood tests and ECG. On surgery day: intraocular pressure (IOP) will be measured.
- Trial name
- NCT04484155
- Testing
- Minimally Invasive Micro Sclerostomy (MIMS)
- Where
- India
- Volunteers
- 31 people
- Sponsor
- Sanoculis Ltd
Primary Open Angle Glaucoma, Normal Tension Glaucoma
Advanced Glycation End Products as a Biomarker for Accelerated Ageing
Globally primary open angle glaucoma (POAG) affects over 60 million people. The exact pathogenesis of POAG is poorly understood. A significant risk factor for glaucoma is advancing age.
- Conditions
- Primary Open Angle Glaucoma, Normal Tension Glaucoma, Ocular Hypertension
- Trial name
- NCT02863224
- Where
- United Kingdom
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University of Plymouth
Ocular Hypertension, Glaucoma
Foot Reflexology in Ocular Hypertensive and Glaucoma Patients
To determine the effect of foot reflexology in primary open angle glaucoma (POAG) patients and the effect of a shoe insert to perform continuous foot reflexology in ocular hypertensive (OHTN) patients.
- Trial name
- NCT04695314
- Testing
- Massage, Experimental insert
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Temple University
Glaucoma, Primary Open Angle (POAG), Ocular Hypertension
Determination Of Predictive Factors Allowing To An Additional 10% Reduction Of Intra-Ocular Pressure
To determine the predictive factors of a positive response to latanoprost 0.005% / timolol 0.5% fixed combination (defined as a 10% IOP reduction from baseline), after 12 weeks of treatment (age, sex, ethnic origin, patient's…
- Trial name
- PREDICOM (NCT00230763)
- Testing
- GSS questionnaire, IOP, LATANOPROST 0.005% / TIMOLOL 0.5% FIXED COMBINATION
- Where
- 102 sites in France
- Volunteers
- 396 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Glaucoma
Study Comparing the P200TE and the P200TxE in Glaucoma Patients
The study evaluates the image quality between two OCT devices.
- Trial name
- NCT03912584
- Testing
- P200TE, P200TxE
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Optos, PLC
Glaucoma
Is There a Response of Glaucoma to Baduanjin Exercise in Elders?
glaucoma is prevalent between elders. Baduanjin exercise is a suitable exercise for elders. elders with glaucoma will divided to group I or group II. each/every group will contain 30 elders.
- Trial name
- NCT07163676
- Testing
- Baduanjin exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Glaucoma, Ocular Hypertension
Safety and Efficacy of TimoD Sustained-Release Implant in Participants With Glaucoma or Ocular Hypertension Undergoing Cataract Surgery
The goal of this clinical trial is to test a new method to deliver an approved medicine called Timolol in the eye of participants with glaucoma or ocular hypertension and requiring cataract surgery.
- Trial name
- NCT07036510
- Testing
- TimoD implant, Injector system, Timolol eye drops 0.5%
- Where
- Panama
- Volunteers
- 42 people
- Sponsor
- EyeD Pharma
Glaucoma
Instrument for Glaucoma Early Detection and Monitoring
To introduce a rapid and objective electrophysiological technique that can assess visual function in the magnocellular pathway, which is thought to be affected in early-stage glaucoma.
- Trial name
- IGDM (NCT00578110)
- Testing
- Glaucoma Diagnosis, Name: Neucodia
- Where
- 5 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Synabridge Corporation
Ocular Hypertension, Open Angle Glaucoma
Study of INS115644 Ophthalmic Solution in Subjects With Ocular Hypertension or Glaucoma
The purpose of this trial is to evaluate the safety and tolerability of INS115644 Ophthalmic Solution in subjects with bilateral ocular hypertension or early primary open angle glaucoma and to investigate the intraocular pressure…
- Trial name
- NCT00443924
- Testing
- INS115644 Ophthalmic Solution
- Volunteers
- 56 people
- Sponsor
- Merck Sharp & Dohme LLC
Ocular Hypertension
Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension
The purpose of this study is to assess the safety and efficacy of Bimatoprost/Timolol Fixed Combination in patients with glaucoma or ocular hypertension
- Trial name
- NCT00332059
- Testing
- bimatoprost/timolol fixed combination
- Where
- 4 sites in United States, Austria and 2 more
- Volunteers
- 445 people
- Sponsor
- Allergan
Glaucoma
Prevalence of Glaucoma in the Israeli Arab Population
there is a variety of glaucoma prevalence within different populations. this study examine the prevalence of glaucoma in the Arab population in Israel' as well as the demographic variables and the compliance to treatment in the…
- Trial name
- NCT01546740
- Where
- Israel
- Volunteers
- 15,000 people
- Sponsor
- Ziv Hospital
Glaucoma and Ocular Hypertension, Diabetic Macular Edema
Effect of Dexamethasone Implant on Optic Disc
This study evaluates the effect of dexamethasone implant which is an intraocular corticosteroid on the optic nerve fibers. Retinal nerve fiber thicknesses and optic nerve head pitting rates were measured before and 6 months after…
- Conditions
- Glaucoma and Ocular Hypertension, Diabetic Macular Edema, Intravenous Drug Usage, Optic Disk Disorders
- Trial name
- NCT03927118
- Testing
- intravitreal dexamethasone implant application
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Ocular Hypertension, Open-Angle Glaucoma
A Phase 2 Single-Masked, Randomized Study of Latanoprost PPDS in Ocular Hypertension or Open-Angle Glaucoma
Determine efficacy of the latanoprost punctal plug. Effect of configuration of L-PPDS placement on efficacy will also be examined.
- Trial name
- NCT02014142
- Testing
- Latanoprost Punctal Plug Delivery System (L-PPDS)
- Where
- 18 sites in United States
- Volunteers
- 86 people
- Sponsor
- Mati Therapeutics Inc.
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