Clinical trials: Glaucoma Diagnosis
Glaucoma, Glaucoma Open-Angle
Electrical Stimulation for Vision Neuroenhancement in Glaucoma
The purpose of the study is to evaluate the efficacy, transorbital alternating current stimulation (rtACS) using the EYETRONIC for the treatment in patients with glaucoma.
- Trial name
- NCT06685211
- Testing
- Eyetronic rtACS
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Glaucoma
Triamcinolone for Ahmed Glaucoma Valve
This triple-blind, stratified, randomized clinical trial includes 100 eyes of 100 patients aged 18 to 85 years with refractory glaucoma.
- Trial name
- NCT02653963
- Testing
- Adjunctival Triamcinolone
- Where
- Iran
- Volunteers
- 106 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Glaucoma, Open-Angle
GATT Versus Canaloplasty (GVC)
Study aims to compare the effectiveness and safety profile of Gonioscopy-assisted Transluminal Trabeculotomy and canaloplasty, in order to find out if one operation is superior to the other.
- Trial name
- NCT05366647
- Testing
- canaloplasty, Gonioscopy-assisted Transluminal Trabeculotomy
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Bialystok
Glaucoma
How Safe and Effective is Micropulse Transscleral Cyclophotocoagulation in Patients With Uncontrolled Glaucoma?
The purpose of this study is to investigate the surgical outcomes of the micropulse transscleral cyclophotocoagulation (mTSCPC) in patients with uncontrolled glaucoma; analyze intraocular pressure lowering effect; and correlate…
- Trial name
- TSCPC (NCT02627352)
- Testing
- Micropulse Transscleral Cyclophotocoagulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Wills Eye
Glaucoma, Ocular Hypertension
Safety and Efficacy of Adding AZARGA® Adjunctive to Prostaglandin Therapy
The purpose of this study was to evaluate the safety and efficacy of adding AZARGA® as a single agent to prostaglandin monotherapy in patients with either ocular hypertension or primary open-angle glaucoma.
- Trial name
- NCT01263444
- Testing
- Brinzolamide 1% / timolol 0.5% Fixed Combination, Habitual prostaglandin monotherapy
- Volunteers
- 47 people
- Sponsor
- Alcon Research
Glaucoma
Serum Citrate in Diagnosis and Follow-up for Glaucoma
Glaucoma might be a mitochondria associated disease. Since citrate is a major component in mitochondrial metabolism its determination in blood might serve as a biomarker.
- Trial name
- NCT00804063
- Testing
- drawing blood sample
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Healthy Eyes, Eye Diseases
Triton Agreement and Precision Study
To Compare the agreement and precision between the Topcon DRI OCT Triton and the 3D OCT-1 Maestro with RDB.
- Trial name
- NCT03080714
- Testing
- Topcon DRI OCT Triton (plus), 3D OCT-1 Maestro
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.
Primary Open Angle Glaucoma
Surgical Approaches in Treating Uncontrolled Glaucoma in Black African and African-Caribbeans
The aim is to perform a randomised feasibility trial preceding a large prospective randomised controlled trial (RCT) comparing three surgical methods - trabeculectomy with Mitomycin C (MMC), primary Baerveldt tube with MMC and…
- Trial name
- PEACE (NCT02989207)
- Testing
- Trabeculectomy, Baerveldt tube surgery, mitomycin-C
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Neovascular Glaucoma, Type 2 Diabetes
Observation of Iris Blood Flow Via OCTA in Diabetic Neovascular Glaucoma
The goal of this observational study is to quantify iris blood flow via non-invasive eye scanning for evaluating ocular lesions in adults aged 18 years and older, including healthy volunteers, patients with type 2 diabetes…
- Trial name
- NCT07722910
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Qilu Hospital of Shandong University
Glaucoma
Tolerability of an Anesthesia-free Tonometer Tip
The purpose of this study is to compare the tolerability and comfort of 4 different prototype anesthesia-free tonometer tips with the standard tonometer tip in conjunction with anesthesia.
- Trial name
- NCT06585423
- Testing
- Sterile commercially available bandage contact lens, Medical grade silicone of a thickness <100 µm, Medical grade silicone of a thickness >100 µm
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Duke University
Eye Disease
The DIOXXACT Trial(Diurnal IOP and OBF Xalatan vs Xalatan And Cosopt Trial)
Diurnal and intervisit fluctuations in IOP are strongly associated with progression of open angle glaucoma and therefore need to be minimized.
- Trial name
- DIOXXACT (NCT00957190)
- Testing
- Dorzolamide 20 mg and Timolol 5 mg
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Glaucoma, Open-Angle, Ocular Hypertension
Safety and Efficacy of a Glaucoma Drug Delivery System
The purpose of this study is to evaluate the ocular safety and efficacy of a glaucoma drug delivery system in open-angle glaucoma or ocular hypertension.
- Trial name
- NCT00824720
- Testing
- High Dose Device, Low Dose Device
- Where
- 4 sites in United States
- Volunteers
- 55 people
- Sponsor
- Vistakon Pharmaceuticals
Glaucoma, Open-Angle, Ocular Hypertension
Safety and Pharmacodynamics Study of AGN-207281 Ophthalmic Solutions Compared With Timolol Ophthalmic Solution or Placebo in Patients With Ocular Hypertension or Primary Open-Angle Glaucoma
This is an exploratory study that will evaluate the safety and pharmacodynamics of up to 3 doses of AGN-207281 based on an ongoing review of data during the study period compared with timolol ophthalmic solution or placebo in…
- Trial name
- NCT01215786
- Testing
- timolol ophthalmic solution 0.5%
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Allergan
Glaucoma
Intraocular Pressure (IOP) Changes Associated With Muslim Prayer Postural Changes
Elevated intraocular pressure is widely accepted as a risk factor for glaucoma and controlling the pressure remains the cornerstone of effective treatment.
- Trial name
- NCT00454025
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Open Angle Glaucoma, Ocular Hypertension
Travoprost Ophthalmic Topical Cream for Open-angle Glaucoma or Ocular Hypertension
The goal of this clinical trial is to learn about the safety of Travoprost Ophthalmic Topical Cream and how well it works in lowering high intraocular pressure (IOP) in patients with open-angle glaucoma (OAG) or ocular…
- Trial name
- NCT06152861
- Testing
- Travoprost Ophthalmic Topical Cream low-dose, Travoprost Ophthalmic Topical Cream mid-dose, Travoprost Ophthalmic Topical Cream high-dose
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Glaukos Corporation
Glaucoma
The Aim of This Study is to Investigate the Correlation Between the Severity of Glaucoma and Corneal Biomechanics as Well as Anterior Chamber Parameters.
The ocular biomechanical differences between the normal control group and primary glaucoma patients, including those treated with conventional medication, laser therapy, and surgery, were compared.
- Trial name
- NCT06340061
- Testing
- Observational study
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Henan Provincial People's Hospital
Primary Open-Angle Glaucoma, Ocular Hypertension
Bimatoprost Ocular Insert Compared to Topical Timolol Solution in Patients With Glaucoma or Ocular Hypertension
The objective of this Phase 2 study is to evaluate whether the Bimatoprost Ocular Insert is non-inferior to that of timolol ophthalmic solution (0.5%) at 12 weeks.
- Trial name
- NCT01915940
- Testing
- Bimatoprost, Timolol 0.5%
- Where
- 10 sites in United States
- Volunteers
- 169 people
- Sponsor
- ForSight Vision5, Inc.
Glaucoma, Quality of Life (QOL)
Triplenex (triple Fixed Combination) Use Evaluation in Patients with Glaucoma
This project purpose is to evaluate the effectiveness, ocular surface quality, medication adherence and quality of life in 46 glaucoma patients in use of three separate drugs (Bimatoprost 0.3%, Timolol Maleate 0.5% and…
- Trial name
- NCT06761313
- Testing
- Triple combination formula, Bimatoprost .03% sterile ophthalmic solution
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Glaucoma
Results of Different Location of Ahmed Glaucoma Valve Implantation in Refractory Glaucoma, Superior Versus Inferior
Purpose:To compare the efficacy and safety of Ahmed Glaucoma Valve (AGV) implantation in the superior versus inferior quadrants.
- Trial name
- NCT00628173
- Testing
- AGV implantation
- Volunteers
- 106 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Neovascular Age Related Macular Degeneration (AMD), Open Angle Glaucoma
TF (SENSIMED Triggerfish) in Intraocular Anti-VEGF (Vascular Endothelial Growth Factor) Injection
This is a prospective, open label study assessing the 24-hour IOP patterns using TF in patients undergoing anti-VEGF injection for the treatment of neovascular AMD (age related macular degeneration).
- Trial name
- NCT01983579
- Testing
- Intraocular anti-VEGF injection, SENSIMED Triggerfish
- Where
- Spain
- Volunteers
- 4 people
- Sponsor
- Sensimed AG
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