Clinical trials: Glaucoma Eye
Open-Angle Glaucoma, Ocular Hypertension
A Comfort Study of Brinzolamide 1% / Brimonidine 0.2% Fixed Combination, Brinzolamide 1% and Brimonidine 0.2%
The purpose of this study was to describe the ocular discomfort immediately upon instillation of Brinzolamide 1%/Brimonidine 0.2% Tartrate Ophthalmic Suspension, Brinzolamide 1% Ophthalmic Suspension, and Brimonidine Tartrate…
- Trial name
- NCT01426867
- Testing
- Brinzolamide 1%/brimonidine tartrate 0.2% ophthalmic suspension, Brinzolamide ophthalmic suspension, 1%, Brimonidine tartrate ophthalmic solution, 0.2%
- Volunteers
- 103 people
- Sponsor
- Alcon Research
Healthy Subjects
SENSIMED Triggerfish® in Sitting and Supine Position
The purpose of the study is to evaluate changes in intraocular pressure (IOP) between sitting and supine body positions and correlate the values obtained with conventional tonometers to the output provided by the investigational…
- Trial name
- NCT01347229
- Testing
- SENSIMED Triggerfish®
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sensimed AG
Posterior Vitreous Detachment, Vitreomacular Traction
Vitreopapillary Interface and Optic Disc Morphology
The vitreous fills the posterior chamber of the eye and is firmly attached, at the posterior pole, to the macula and the optic nerve head (ONH).
- Conditions
- Posterior Vitreous Detachment, Vitreomacular Traction, Glaucoma, Vitreopapillary Traction
- Trial name
- NCT02290795
- Testing
- OCT imaging/HRT imaging
- Where
- Belgium
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Glaucoma, Intraocular Pressure
Intraocular Pressure During Static Apnea
This prospective observational study evaluated changes in intraocular pressure (IOP) during dry static apnea (STA) in breath-hold divers.
- Conditions
- Glaucoma, Intraocular Pressure, Apnea
- Trial name
- NCT07604428
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Olomouc
Open-angle Glaucoma, Ocular Hypertension
Safety and Intraocular Pressure (IOP) Lowering Efficacy of Low Dose Travoprost
The purpose of this study is to compare the safety and IOP-lowering efficacy of various low dose travoprost formulations in patients with open-angle glaucoma or ocular hypertension.
- Trial name
- NCT00637130
- Testing
- Travoprost ophthalmic solution, 0.0008%, Travoprost ophthalmic solution, 0.001%, Travoprost ophthalmic solution, 0.0012%
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Alcon Research
Glaucoma
Comparison of Silicone and Porous Plate Ahmed Glaucoma Valves
The purpose of this study is to evaluate and compare the clinical outcomes after implantation of the porous plate (polyethylene) (Model M4) Ahmed Glaucoma Valve with the silicone plate Ahmed Glaucoma Valve (Model FP7) in…
- Trial name
- NCT01883856
- Testing
- Silicone plate Ahmed Glaucoma Valve (Model FP7), Porous Plate Ahmed Glaucoma Valve (Model M4)
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Peter Netland, MD
Glaucoma, Acupuncture
Clinical Evaluation of Acupuncture in Treating Glaucoma
The present study predicts that acupuncture or electroacupuncture can reduce intraocular pressure and also can improve quality of life in patients with glaucoma.
- Trial name
- NCT04157530
- Testing
- wang-bu-liu-xing, acupuncture, Electroacupuncture
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- China Medical University Hospital
Glaucoma
Home Tonometry With the I-care Tonometer for Glaucoma
The overall objective of the study is to scope the self-management for self-monitoring glaucoma using home tonometry.
- Trial name
- NCT02656836
- Testing
- Home tonometry, diagnostic study
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Queen's University, Belfast
Glaucoma, Ocular Hypertension
Evaluation Of Intraocular Pressure Lowering-Effect Of Xalacom In Patients With Poag Or Oh.
This study is designed as an open label evaluation of the efficacy of latanoprost and timolol fixed combination (Xalacom) after 6 month of treatment. Eligible patients may be enrolled at the baseline visit.
- Trial name
- NCT00143208
- Testing
- Xalacom
- Where
- 21 sites in Italy
- Volunteers
- 250 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Ocular Hypertension, Primary Open Angle Glaucoma of Both Eyes
Is the Reduction in IOP After Treatment of 180 Degrees Equivalent to Treatment of 360 Degrees With SLT?
The study is a prospective randomised controlled intervention comparing the intraocular pressure outcomes following Selective Laser Trabeculoplasty (SLT) treatment of 180 degrees SLT compared to 360 degrees in treatment naive…
- Conditions
- Ocular Hypertension, Primary Open Angle Glaucoma of Both Eyes, Intraocular Pressure
- Trial name
- SLT (NCT03529591)
- Testing
- Selective laser trabeculoplasty (SLT), Selective laser trabeculoplasty
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Western University, Canada
Glaucoma
Assessment of the Ability to Distinguish Odors in Glaucoma Patients
Glaucoma is one of the leading causes of blindness worldwide. The key feature of glaucoma is damage to the optic nerve head with loss of retinal ganglion cells and local tissue remodeling.
- Trial name
- NCT00304824
- Volunteers
- 30 people
- Sponsor
- University Hospital, Basel, Switzerland
Glaucoma
VW-50 Feasibility Study
An investigator-initiated 10-participant Feasibility Study to assess a novel glaucoma drainage implant, VW-50.
- Trial name
- NCT07730424
- Testing
- Surgical implantation of VW-50
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Melbourne Eye Specialists
Ocular Hypertension, Glaucoma
Tolerance and Effect on Intraocular Pressure After Administration of SYL040012
The purpose of this study is to determine whether SYL040012 is safe for the treatment of ocular hypertension and glaucoma.
- Trial name
- NCT00990743
- Testing
- SYL040012
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sylentis, S.A.
Glaucoma, Open-angle, Ocular Hypertension
A Long-term Safety Study of Once-daily Travatan
Long term safety study of TRAVATAN in patients with Open-angle glaucoma or ocular hypertension.
- Trial name
- NCT00051168
- Testing
- Travatan
- Where
- United States
- Volunteers
- 502 people
- Sponsor
- Alcon Research
Glaucoma, Ocular Hypertension
Surgical and Refractive Outcomes of Combined Glaucoma Surgery
The aim of the study is to examine surgical and refractive outcomes of glaucoma combined surgery in six months period of follow up
- Conditions
- Glaucoma, Ocular Hypertension, Filtering Surgery
- Trial name
- NCT04335825
- Testing
- phacotrabeculectomy, ExPress antiglaucoma surgery combined with phacoemulsification
- Volunteers
- 81 people
- Sponsor
- Medical University of Bialystok
Glaucoma, Glaucoma, Open Angle
SOLX Titanium Sapphire Laser for Trabeculoplasty
Use of the Titanium Sapphire laser for laser trabeculoplasty to reduce intraocular pressure in patients with poorly controlled intraocular pressure on maximally tolerated medical therapy or prior failed laser trabeculoplasty.
- Trial name
- NCT00145535
- Testing
- SOLX Titanium Sapphire Laser (TiSaLT), Argon Laser Trabeculoplasty (ALT)
- Where
- 10 sites in United States, Canada and 2 more
- Volunteers
- 120 people
- Sponsor
- SOLX, Inc.
Primary Congenital Glaucoma
Iris Tissue in Primary Congenital Glaucoma
To present the histopathological features of the iris tissue in primary congenital glaucoma which may play a role in pathogenesis
- Trial name
- NCT04079725
- Testing
- Combined trabeculotomy-trabeculectomy with mitomycin c
- Volunteers
- 15 people
- Sponsor
- Assiut University
Glaucoma, Filtering Surgery
Long-Term IOP Fluctuation and VF Progression After Triple Procedure
Long-term intraocular pressure (IOP) fluctuation may be significantly associated with the progression of glaucomatous visual field loss, even in patients kept always low IOP after triple procedure, an effective approach for…
- Conditions
- Glaucoma, Filtering Surgery, Intraocular Pressure
- Trial name
- NCT00428740
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Yonsei University
Open Angle Glaucoma, Primary Open Angle Glaucoma
Safety and Effectiveness of the Hydrus Microstent
The purpose of this study is to assess the safety and effectiveness of the Hydrus Microstent for lowering intraocular pressure (IOP) in pseudophakic patients with open-angle glaucoma for whom IOP is not sufficiently controlled on…
- Conditions
- Open Angle Glaucoma, Primary Open Angle Glaucoma, Pseudoexfoliation Glaucoma, Pigmentary Glaucoma
- Trial name
- FRONTIER (NCT05198297)
- Testing
- Hydrus Microstent, Ophthalmic surgery
- Where
- 5 sites in United States
- Volunteers
- 33 people
- Sponsor
- Alcon Research
Glaucoma, Ocular Hypertension
Efficacy of Selective Laser Trabeculoplasty in Patients Under Treatment With Topical Prostaglandines
Retrospective analysis of efficacy of selective laser trabeculoplasty in patients under treatment with topical prostaglandins compared to patients without topical prostaglandins is performed.
- Trial name
- NCT01467440
- Testing
- Selective Laser Trabeculoplasty
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University of Zurich