Clinical trials: Glaucoma Therapy
Open-angle Glaucoma
A Multicenter Study of the Pigmentation in the Trabecular Meshwork After Two Years of Treatment With TRAVATAN 0.004% Ophthalmic Solution
The purpose of this study was to assess the pigmentation in the trabecular meshwork of patients who had been treated for at least 2 years with TRAVATAN compared with patients without exposure (or less than 1 month) to a…
- Trial name
- NCT01485822
- Testing
- Trabecular Meshwork Tissue Collection, Travoprost 0.004% ophthalmic solution
- Volunteers
- 88 people
- Sponsor
- Alcon Research
Glaucoma, Dry Eye Syndrome
Eye Drop Use in Glaucoma Patients Through Patient Surveys and Video Observations
This study will be used to evaluate how patients put eye drops in their eyes and any problems that may arise from this activity.
- Conditions
- Glaucoma, Dry Eye Syndrome, Conjunctivitis
- Trial name
- NCT00522600
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Robin, Alan L., M.D.
Glaucoma
Glaucoma Treatment by Cyclo-coagulation Using High Intensity Focused Ultrasound (HIFU)
The purpose of this study is to evaluate the effectiveness and the safety of the cyclocoagulation using High Intensity Focused Ulatrsound with the EYEOP1 device in glaucoma patients
- Trial name
- NCT01592955
- Testing
- EYEOP1
- Where
- 7 sites in Israel, Italy and 2 more
- Volunteers
- 84 people
- Sponsor
- EyeTechCare
Open-Angle Glaucoma, Ocular Hypertension
Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-01-69
To compare intraocular pressure lowering effectiveness of a combination drug vs. two individual drugs dosed alone.
- Trial name
- NCT00047515
- Testing
- Alcon Investigational Agent
- Where
- United States
- Sponsor
- Alcon Research
Open-angle Glaucoma, Ocular Hypertension
Phase II Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-angle Glaucoma or Ocular Hypertension Patients
The purpose of this study is to determine the safety and IOP-lowering ability of a glaucoma therapy in patients with open-angle glaucoma or ocular hypertension.
- Trial name
- NCT00069706
- Testing
- AL-12182 0.003% Ophthalmic Solution, AL-12182 Ophthalmic Solution Vehicle, Latanoprost 0.005% Ophthalmic Solution
- Volunteers
- 118 people
- Sponsor
- Alcon Research
Glaucoma
Multi-Arm Feasibility Study Evaluating OTX-TP Compared to Timolol in Treatment of Subjects With Open Angle Glaucoma
The purpose of this study is to evaluate how OTX-TP, a sustained release travoprost drug product, when placed in the canaliculus of the eyelid compares to timolol drops for the lowering of intraocular pressure (IOP) in patients…
- Trial name
- NCT01845038
- Testing
- OTX-TPa ~4µg/day over 2 mos. with natural tears drops, OTX-TPb ~3µg/day over 3 months with natural tears drops, Timolol Maleate (0.5%) dosed twice daily with punctum plug without drug
- Where
- South Africa
- Volunteers
- 41 people
- Sponsor
- Ocular Therapeutix, Inc.
Medication Adherence, Glaucoma
The eyeGuide: Improving Glaucoma Self-management With a Personalized Behavior Change Program
The purpose of this research study is to test the impact of two personalized technology based programs that may help improve adherence to glaucoma medications.
- Trial name
- eyeGuide (NCT03159247)
- Testing
- eyeGuide
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- University of Michigan
Glaucoma, Open-Angle
GATT Versus Canaloplasty (GVC)
Study aims to compare the effectiveness and safety profile of Gonioscopy-assisted Transluminal Trabeculotomy and canaloplasty, in order to find out if one operation is superior to the other.
- Trial name
- NCT05366647
- Testing
- canaloplasty, Gonioscopy-assisted Transluminal Trabeculotomy
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Bialystok
Primary Open Angle Glaucoma, Hypertension Ocular
Effects of Magnetic Therapy and Seawater Combined in Decreasing Intraocular Presion.
Glaucoma is among the leading causes for blindness in the western world. Elevated intraocular pressure (IOP) has been identified as the most important risk factor.
- Trial name
- GME (NCT02300818)
- Testing
- Pulsed Electromagnetic Field Therapy, Seawater eyedrops
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- American Society Of Thermalism And Climatology Inc
Glaucoma Secondary
Treatment of Malignant Glaucoma by Anterior Vitrectomy From Two Different Approaches
To compare the surgical outcomes of treating phacoemulsification with intraocular lens implantation combined with goniosynechialysis (Phaco-IOL-GSL) associated malignant glaucoma (MG), using different incision sites in anterior…
- Trial name
- NCT04172857
- Testing
- anterior vitrectomy combined with hyaloidotomy, zonulectomy and iridectomy
- Volunteers
- 9 people
- Sponsor
- Wenzhou Medical University
To See the Safety and Efficacy of the Topical Latanoprost Compared With Topical Brimonidine in the Treatment of the Primary Open Angle Glaucoma Patients
The Effectiveness of Topical Latanoprost Compared With Topical Brimonidine in the Treatment of the Primary Open Angle Glaucoma
Outpatient department of cmch, ceitc,cimch POAG patients enrolled for the study.
- Trial name
- NCT04205201
- Testing
- Drugs, Investigational
- Where
- 2 sites in Bangladesh
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chittagong Medical College
Open Angle Glaucoma
Micropulse Laser Trabeculoplasty (MLT) Versus Selective Laser Trabeculoplasty (SLT) for Treatment of Open Angle Glaucoma
The purpose of this study is to evaluate the effectiveness of a new laser (called Micropulse Laser Trabeculoplasty or MLT) in the treatment of glaucoma compared to the conventional laser presently used which is called selective…
- Trial name
- NCT01956942
- Testing
- Micropulse Laser Trabeculoplasty, Selective Laser Trabeculoplasty
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- David Belyea
Age-Related Macular Degeneration
The Role of Occupational Therapy for Improving Medication Management for Persons With AMD, DR and Glaucoma
The goal of this clinical trial is to learn if education about additional task lighting, enhanced contrast, enlarged print instructions, smart apps and organizational strategies will improve medication management skills.
- Trial name
- NCT06593405
- Testing
- occupational therapy interventions for low vision care
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- MCPHS University
Glaucoma
Primary Glaucoma Treatment Trial in Kenya and South Africa - SLT vs. Medication
Multi-centre randomised controlled trial of selective laser trabeculoplasty compared with prostaglandin analogue therapy as primary treatment for high tension open angle glaucoma.
- Trial name
- SLT/med (NCT02774811)
- Testing
- Prostaglandin analogue, Selective laser trabeculoplasy, laser
- Where
- Kenya
- Volunteers
- 15 people
- Sponsor
- University College, London
Glaucoma
Dual Intravitreal Implantation of NT-501 Encapsulated Cell Therapy for Glaucoma
To determine the safety and efficacy over 24 months of dual NT-501 CNTF encapsulated cell therapy (ECT) on visual impairment related to glaucoma.
- Trial name
- NCT04577300
- Testing
- NT-501
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University