Clinical trials: Global Mental Health
Generalized Anxiety Disorder (GAD)
The Effect of Patient Preference for Treatment Model in Internet Delivered Cognitive Behavior Therapy for Generalized Anxiety Disorder
The goal of this clinical trial is to investigate the effect of allowing patients to choose between two internet-based cognitive behavioral treatments (ICBT) for generalized anxiety disorder (GAD).
- Trial name
- ORIGAMI (NCT07201844)
- Testing
- Metacognitive Internet delivered Cognitive Behavior Therapy, Intolerance of uncertainty based Internet delivered Cognitive Behavior Therapy
- Where
- Sweden
- Volunteers
- 440 people
- Sponsor
- Karolinska Institutet
Anxiety Disorders
Online, Guided Interventions to Reduce Generalized Anxiety Disorder Among Indian University Students
This controlled, three-arm, randomized (1:1:1), multi-site trial will evaluate the efficacy, feasibility and acceptability of cognitive-behavioral therapy (CBT)-based online guided and unguided self-help intervention to reduce…
- Trial name
- NCT02410265
- Testing
- Lantern: Guided self-help program, Mental Health Online: Self-help program
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Stanford University
Child Behavior Problem, Mental Health Issue
Supporting Parents & Kids Through Lockdown Experiences (SPARKLE).
Throughout the COVID-19 pandemic, reduced access to childcare, money- and health-related worries and extended confinement and social isolation have placed great pressure on many families.
- Trial name
- SPARKLE (NCT04786080)
- Testing
- Parent Positive
- Where
- United Kingdom
- Volunteers
- 646 people, healthy volunteers welcome
- Sponsor
- King's College London
Knowledge Translation, Cognitive Impairment
Preventing and Managing Cognitive Impairment
This randomized controlled trial (RCT) is used to address the knowledge translation of primary care practitioners (PCPs) for the early identification of cognitive impairment.
- Trial name
- CognitnECHO (NCT05471141)
- Testing
- Cognition ECHO
- Sponsor
- Charles Drew University of Medicine and Science
Chronic Fatigue Syndrome, Fibromyalgia
Compare the Medical Conditions of Gulf War Veterans to Non-Deployed Veterans
Primary Hypothesis: Gulf War veterans will have an equal prevalence or mean level of the following medical and psychological conditions frequently reported in the literature compared to a control group of nondeployed veterans…
- Conditions
- Chronic Fatigue Syndrome, Fibromyalgia, Post-Traumatic Stress Disorder, Neurologic Abnormalities
- Trial name
- NCT00032461
- Volunteers
- 2,000 people
- Sponsor
- US Department of Veterans Affairs
Chronic Conditions, Multiple, Diseases of the Circulatory System
National Institute for Health and Care Research Global Health Research Centre for Multiple Long-Term Conditions
Multiple Long-Term Conditions (MLTC), defined as the coexistence of two or more chronic conditions, is increasingly prevalent in India.
- Conditions
- Chronic Conditions, Multiple, Diseases of the Circulatory System, Diseases of the Respiratory System, Endocrine, Nutritional and Metabolic Diseases
- Trial name
- NIHR-GHRC MLTC (NCT07582380)
- Testing
- Electronic Decision Support System (EDSS), Assisted Telemedicine, Patient-facing app for self-management, supported by care coordination through Community Champions and Care Coordinators.
- Where
- 120 sites in India, Nepal
- Volunteers
- 3,600 people
- Sponsor
- Centre for Chronic Disease Control, India
Gender Relations, Reproductive Health
Global Early Adolescent Study - Kinshasa
The Global Early Adolescent Study (GEAS) is the first international study exploring how gender norms evolve over time and inform a spectrum of adolescent health outcomes, including sexual and mental health, through the adolescent…
- Trial name
- GEAS_KI (NCT03610568)
- Testing
- Growing up GREAT! Intervention
- Where
- Democratic Republic of the Congo
- Volunteers
- 2,862 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Depression Disorder, Anxiety
Impact of Nut Consumption on Mental Health in Young Adults
Nuts have a high nutrient density, and numerous studies have reported their cardiometabolic benefits. Although observational studies in adults have indicated a potential link between nut consumption and improved mental health…
- Conditions
- Depression Disorder, Anxiety, Mental Health, Stress
- Trial name
- NUTS4BRAIN-RCT (NCT07292610)
- Testing
- mixed nuts. Group A, mixed nuts. Group B, control group
- Where
- Spain
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Health Behavior
Health Behavior Change During COVID-19 Pandemic
This study aims at investigating handwashing behavior during COVID-19 pandemic. It was hypothesized that social-cognitive and emotional predictors as well as COVID-19 morbidity and mortality rates within the country would be…
- Trial name
- NCT04367337
- Testing
- No intervention
- Where
- 14 sites in Australia, Canada and 12 more
- Volunteers
- 6,079 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Depression / Major Depressive Disorder, Anxiety Disorder (Panic Disorder or GAD)
Feasibility and Preliminary Outcomes of Compassion-Focused Group Therapy for Depression and Anxiety
This pilot study evaluated the feasibility and preliminary outcomes of compassion-focused group therapy (CFT) for adults with depression and/or anxiety who continued to experience symptoms despite previous treatment.
- Trial name
- NCT07876453
- Testing
- Compassion-Focused Group Therapy (CFT)
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- Karolinska Institutet
Post-Acute Sequelae of SARS-CoV-2 Infection, Long COVID
Observational Study of Intranasal IVIG in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Patients Undergoing Medical Tourism
This observational study is being conducted by Healing Hope International to collect real-world data on an emerging treatment approach for Long COVID in patients with immunodeficiency.
- Conditions
- Post-Acute Sequelae of SARS-CoV-2 Infection, Long COVID, Long COVID Fatigue, Long COVID Syndrome
- Trial name
- IVIG-LC (NCT06992401)
- Volunteers
- 50 people
- Sponsor
- Tamara C Tamas
Anxiety Disorders Generalized, Depression
Feasibility Trial of an Online Course (eMB) to Reduce Anxiety and Depression for Pregnant Women and Their Partners
This pilot study engaged pregnant couples experiencing elevated symptoms of maternal anxiety or depression with an existing online psychoeducation intervention, the Online Mothers and Babies Course (eMB).
- Trial name
- NCT05867680
- Testing
- Online Mothers and Babies Course (eMB)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Missouri-Columbia
Psychiatric Disorder, Schizophrenia
Improving Physical Health in Patients With Psychiatric Disorders in General Practice (SOFIA)
People with a severe mental illness (SMI) have an increased risk for premature mortality, predominantly due somatic health conditions.
- Conditions
- Psychiatric Disorder, Schizophrenia, Bipolar Disorder, Severe Depression
- Trial name
- SOFIA (NCT04618250)
- Testing
- SOFIA model
- Where
- Denmark
- Volunteers
- 76 people
- Sponsor
- University of Copenhagen
Mental Health and General Well-being
Effect of a Brief Daily Digital Meditation on Well-Being in US Young Adults (BEGIN II)
This study is testing whether a short, daily, app-based meditation can help young adults feel better in their everyday lives. Adults aged 18-40 years who live in the United States and have not meditated regularly (defined as more…
- Trial name
- BEGIN II (NCT07607782)
- Testing
- Miracle of Mind meditation, Neutral audio learning task
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Generalized Anxiety, Social Phobia
Integrated Mental Health Care and Vocational Rehabilitation to Individuals on Sick Leave Due to Anxiety and Depression
The purpose of this study is to investigate the efficacy of 1) a stepped mental health care intervention and 2) an integrated mental health care and vocational rehabilitation intervention for people on sick leave because of…
- Conditions
- Generalized Anxiety, Social Phobia, Panic Disorder, Depression
- Trial name
- IBBIS (NCT02872051)
- Testing
- IBBIS mental health care and standard vocational rehabilitation, Integrated mental health care and vocational rehabilitation
- Where
- Denmark
- Volunteers
- 631 people
- Sponsor
- Amager Hospital
Depression, Anxiety
Consultation-Liaison Intervention for Patients with Depression and Anxiety in Primary Care
The CoLiPri study is a cluster randomized controlled trial funded by the Swiss National Science Foundation to evaluate the clinical and cost effectiveness as well as the implementation of a complex consultation-liaison…
- Trial name
- CoLiPri (NCT04233853)
- Testing
- CoLiPri intervention, Usual primary care enhanced
- Where
- Switzerland
- Volunteers
- 82 people
- Sponsor
- University of Zurich
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Delirium, Postoperative, Anesthesia
Depth of Anesthesia on Postoperative Delirium and Cognitive After Surgery
The goal of this clinical trial (Balanced-2 study) is to compare light to deep general anesthesia using widely available brain monitors, to see if 'light' anesthesia could reduce rates of delirium, cognitive decline, and…
- Conditions
- Delirium, Postoperative, Anesthesia, Surgery-Complications, Cognition Disorder
- Trial name
- Balanced-2 (NCT06268080)
- Testing
- Depth of anesthesia titration using pEEG
- Where
- 3 sites in New Zealand
- Volunteers
- 2,766 people
- Sponsor
- Auckland City Hospital
Pandemic, COVID-19, Adult ALL
Emotional and Physical Health Status of Adults
To investigate the comparison of differences between emotional and physical health status of adults in COVID-19 isolation period and controlled normalization period.
- Trial name
- NCT05206903
- Testing
- Questionnaires
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Major Depression, Generalized Anxiety
Common Factors Group Psychotherapy for General Mental Health Concerns
The current research will investigate the impact of general psychotherapy using common factors (i.e., techniques and communication skills that are common to all major forms of psychotherapy) to investigate whether mental health…
- Conditions
- Major Depression, Generalized Anxiety, Stress Disorder, Post Traumatic, Stress
- Trial name
- NCT06614842
- Testing
- Common Factors Group Psychotherapy
- Sponsor
- University of Alabama at Birmingham