Clinical trials: Global Surgery
Tongue Cancer
Effects of Different General Anesthesia Methods on Immune Responses in Patients Undergoing Surgery for Tongue Cancer
Surgical excision is the mainstay of treatment for tongue cancer. However, surgery-induced immunosuppression has been implicated in the development of post-operative septic complications and neoplasm metastasis.
- Trial name
- NCT01854021
- Testing
- intravenous anesthesia, combined intravenous-inhalational anesthesia, inhalational anesthesia
- Where
- China
- Volunteers
- 60 people
- Sponsor
- tiejun Zhang
Strabismus
The Effect of Povidone-iodine Ophthalmic Surgical Prep Solution on Respiration in Children Undergoing Strabismus Surgery With General Anesthesia.
Determine whether the application of povidone-iodine ophthalmic solution onto the ocular surface causes a change in respiration in children undergoing strabismus surgery with general anesthesia.
- Trial name
- NCT03349515
- Testing
- Provodine-Iodine Solution, Group B will receive three drops in each eye of ophthalmic balanced salt solution.
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Spine Fusion, Locoregional Anaesthesia
PeriOPerative Spine Surgery COntrol Pain (POPSSCOP) Study: Intrathecal Morphine vs Erector Spinae Plane Block for Postoperative Pain Management in Spinal Fusion
This is a prospective observational study conducted at the trauma center of Città della Salute e della Scienza of Turin. The aim of the study is to compare two local regional anesthesia techniques in multimodal analgesia for…
- Conditions
- Spine Fusion, Locoregional Anaesthesia, Intrathecal Anesthesia, Erector Spina Plan Block
- Trial name
- POPSSCOP (NCT07245524)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Nausea, Emesis
Post- Surgery Recovery: Nerve Blocks w/ Sedation vs. Nerve Block w/ Either Sedation/Gen. Anesthesia
Nausea after surgery may negatively influence patient satisfaction, may delay discharge, and cause unexpected hospital admissions.
- Trial name
- NCT02602080
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Hospital for Special Surgery, New York
Emergency General Surgery
Development and Pilot Testing the SITe Intervention
Every year, nearly 240,000 patients age 60 and older are transferred between acute care hospitals for nontraumatic surgical emergencies, and these patients experience worse outcomes than patients admitted directly from an…
- Trial name
- NCT06118359
- Testing
- Intervention to Support Interhospital Transfer Decisions (SITe)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Wisconsin, Madison
Anesthesia Morbidity, Anesthesia; Adverse Effect
Comparison of CLSB With Sedation Versus General Endotracheal Anesthesia on Postoperative Outcomes in Elderly Patients Undergoing Hip Fracture Surgery
Hip fracture is a global public health problem. The postoperative mortality and disability rate of hip fracture is high, and early surgery is still the most effective treatment method, but these patients are often associated with…
- Trial name
- NCT03318133
- Testing
- anesthesia
- Where
- China
- Volunteers
- 1,086 people
- Sponsor
- Shanghai 6th People's Hospital
Open Abdomen
Assessment of a Non-invasive Device in the Management of Open Abdomen (AbCLO)
The goal of this multicenter, prospective Cohort Interventional study is to perform a pilot study of the AbCLO (Abdominal Wall Closure) device in patients with Open Abdomen.
- Trial name
- AbCLO (NCT06242925)
- Testing
- AbCLO (Abdominal Wall Closure) Device
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Tufts Medical Center
Peripheral Vein Cannulation Guided by Ultrasound
Ultrasound Guided Peripheral Venous Cannulation in Patient Undergoing Elective Surgery Under General Anesthesia.
This study evaluates two different techniques for peripheral venous cannulation in operating theatre. Ultrasound guided insertion of peripheral cannula in comparison with conventional approach without any ultrasound guidance.
- Trial name
- NCT05119985
- Testing
- Peripheral vein cannulation, Cannulation without ultrasound
- Where
- Czechia
- Volunteers
- 860 people, healthy volunteers welcome
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Coping Skills Training for Persistent Post-Surgical Pain, General Health Education
Well-Being After Breast Cancer Surgery
The purpose of this study is to compare the benefits of skills training and health education interventions designed specifically to increase the well-being of people with persistent pain after breast surgery for lobular carcinoma…
- Trial name
- WB ABCs (NCT04225585)
- Testing
- CST-PSP, General health education
- Where
- 2 sites in United States
- Volunteers
- 316 people
- Sponsor
- Duke University
Hip Fractures
Hypobaric Lateral Spinal Anesthesia Versus General Anesthesia for the Hip Fracture Surgery
Hip fracture is a frequent pathology, involving elderly patients with many co-morbidities ; therefore, post-operative morbidity and mortality is high.
- Trial name
- RACHYP (NCT03373864)
- Testing
- Unilateral spinal anesthesia, General anesthesia
- Where
- France
- Volunteers
- 154 people
- Sponsor
- Hospices Civils de Lyon
Neoplasms
A Randomized Controlled Trial of a Robotic Simulation Curriculum to Teach Robotic Suturing
The aim of this study is to determine if training with a robotic simulator improves ability to perform robotic suturing. We aim to recruit 38 participants (attending surgeons or residents in obstetrics and gynecology, urology…
- Trial name
- NCT01811095
- Testing
- Training
- Where
- 2 sites in Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- McGill University
Gingival Recession, Generalized
Cor Adv Flap Plus Ac Derm Matrix in Thin Phenotype Multiple Recessions
Clinical evaluation of conventional and modified coronally advanced flaps combined with acellular dermal matrix graft
- Trial name
- NCT03883438
- Testing
- Modified coronally advanced flap and acellular dermal matrix graft
- Where
- 4 sites in Azerbaijan, Brazil and 2 more
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Aziz Aliyev Azerbaijan State Advanced Training Institute for Doctors
Cognitive Ability, General, Brain Injury
The Effect of Dexmedetomidine to Cognition of Geriatrics in Prolonged Surgery
The incidence of postoperative cognitive dysfunction (POCD) is high and POCD affect the life quality and the prognosis of patients.
- Trial name
- NCT02123355
- Testing
- Induction of anesthesia, Intubation, Sevoflurane, remifentanil ,vecuronium
- Volunteers
- 80 people
- Sponsor
- Shaanxi Provincial People's Hospital
Surgery
The Clinical Efficacy of Supraglottic Airway Device, Self-pressurized Air-Q Intubating Laryngeal Airway (ILA -SP) in Adult Patients: Comparison With Classic-laryngeal Airway (c-LMA)
Supraglottic airway devices (SADs) are well established in anesthetic practice. Among these devices ,classic laryngeal airway has been typically widely used.
- Trial name
- NCT02206438
- Testing
- Insertion of C-LMA, Insertion of air-Q according
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Yonsei University
Anesthesia, ERAS
Impact of General Anesthesia v/s Spinal Anesthesia on ERAS Parameters in Intestinal Stoma Reversal
Randomized, Interventional ,Open labeled, Parallel Assignment and Superiority trial.
- Conditions
- Anesthesia, ERAS, Surgical Stomas, Ileostomy - Stoma
- Trial name
- SPIGERAS (NCT06226753)
- Testing
- Type of anaesthesia used
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Neurocognitive Disorder, General Anesthesia
EVALUATION OF POSTOPERATIVE NEUROCOGNITIVE IMPAIRMENT
In this prospective study, the effects of different anesthesia methods (total intravenous anesthesia and inhaled anesthesia) on neurocognitive function will be examined in patients undergoing breast-conserving surgery without…
- Conditions
- Neurocognitive Disorder, General Anesthesia, Total Intravenous Anesthesia, Sevoflurane Anaesthesia
- Trial name
- NCT06685770
- Testing
- Mini mental state assessment test, Mini-cog test
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Haseki Training and Research Hospital
Geriatrics, Hypotension on Induction
Carotid Artery Corrected Flow Time and Inferior Vena Cava Collapsibility Index for Prediction of Hypotension After Induction of General Anesthesia in Geriatric Patients Undergoing Elective Surgery
In this observational study, we will assess cFT by Carotid ultrasound and IVC collapsibility index for prediction of hypotension after induction of general anesthesia in geriatric patients undergoing elective surgery.
- Conditions
- Geriatrics, Hypotension on Induction, General Anesthetic Drug Adverse Reaction, Elective Surgery
- Trial name
- NCT06814054
- Testing
- Carotid Artery Corrected Flow Time measurement, Inferior vena cava collapsibility index
- Where
- Egypt
- Volunteers
- 189 people
- Sponsor
- Tanta University
Sleep Disordered Breathing
Oxygen Monitoring of Patients After Surgery on the Hospital General Care Floor
The pain medication given after major surgery may cause some patients to stop breathing for periods of time especially at night time. An oxygen monitor may reflect this abnormal breathing pattern.
- Trial name
- NCT01082575
- Testing
- Oxygen Monitoring
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Medtronic - MITG
Wound Infection, Breast Neoplasms
Wound Infections in Breast Cancer Surgery After Preoperative Skin Preparation With Chlorhexidine vs. Povidone-iodine
The development of surgical site infections (SSI) in clean-contaminated surgery is regarded as being preventable. Known to be effective in the prevention of surgical site infection are the adequate sterilization of the surgical…
- Trial name
- NCT02479347
- Testing
- Chlorhexidine, Povidone-Iodine
- Where
- Italy
- Volunteers
- 2,158 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Gastrointestinal Dysfunction
Clinical Study on the Treatment of Gastrointestinal Dysfunction After Knee Joint Surgery Under General Anesthesia With Floating Needle
A randomized controlled trial was conducted to compare the clinical efficacy of Fu's subcutaneous acupuncture and western medication in the treatment of gastrointestinal dysfunction after knee surgery under general anesthesia.
- Trial name
- NCT07607249
- Testing
- Fu's Acupuncture group, Mosapride
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Zhenyu Zhang
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