Clinical trials: Global Surgery
Emergency Surgical Procedures, Postoperative Pain
Postoperative Progressive Relaxation Exercises for Pain and Anxiety After Emergency Surgery
This randomized controlled trial investigated the effectiveness of postoperative progressive relaxation exercises (PRE) on pain, anxiety, and physiological parameters among adult patients undergoing emergency general surgery.
- Conditions
- Emergency Surgical Procedures, Postoperative Pain, Postoperative Anxiety
- Trial name
- PRE-ES (NCT07301073)
- Testing
- Progressive Relaxation Exercises (PRE)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Agri Ibrahim Cecen University
Sepsis, SIRS
The Ward Study for SeptiCyte® Lab to Distinguish Between Infection-positive and Infection-negative SIRS
A non-interventional, prospective observational study to assess the performance of SeptiCyte® Lab to diagnose patients identified as suspected of sepsis in general medical and surgical wards with infection-positive from…
- Trial name
- NCT02704871
- Testing
- SeptiCyte Lab molecular diagnostic test (non-interventional)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Immunexpress
Urologic Diseases
10 Minutes Prewarming and Warmed Intravenous Fluid on Core Temperature
Hypothermia occurs frequently during general anesthesia. This study is to evaluate the efficacy of 10 minutes of prewarming and warmed fluid during urologic surgery.
- Trial name
- NCT04991272
- Testing
- prewarming and warmed fluid infusion
- Where
- South Korea
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Inje University
Airway Complication of Anaesthesia
The Clinical Efficacy of Recently Developed Supraglottic Airway Device, I-gel™, in Neonates and Infants: Comparison With Classic-laryngeal Mask Airway (c-LMA)
Although the safety and efficacy of the Classic-laryngeal mask airway (c-LMA) in children has been shown in several large observational studies, findings suggest that the smaller-sized c-LMAs, in particular sizes 1 and 1½, are…
- Trial name
- NCT01437137
- Testing
- classic-laryngeal mask airway (c-LMA), i-gel™
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Yonsei University
Caudal Block, Pediatric Urologic Surgeries
Comparison of Caudal Block Combined With General Anesthesia and Penile Block and Intravenous Fentanyl in Pediatric Surgeries
Urogenital surgery is one of the most frequently performed surgical procedures in the pediatric patient population. There is no consensus on which analgesic method is most effective for pain control in these patients.
- Conditions
- Caudal Block, Pediatric Urologic Surgeries, Fentanyl, Pediatric Delirium
- Trial name
- NCT06862271
- Testing
- Group 1 ( Caudal block group ), Group 2 (Penile block and IV Fentanyl group)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Miray Gözde Özdemir
Pain, Postoperative
Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia
The purpose of this study is to investigate the effectiveness of various oral analgesic regimens in minimizing post-operative pain and discomfort in young children following dental rehabilitation under general anesthesia (DRGA).
- Trial name
- NCT06757075
- Testing
- Ibuprofen, Acetominophen
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Boston University
Postoperative Sore Throat
Effect of Chewing Gum and Mouthwash Before Operation on Sore Throat After General Anesthesia With a Laryngeal Mask
Postoperative sore throat (POST) is an important problem after general anaesthesia. We assessed whether chewing gum preoperatively or mouthwash can reduce the incidence of POST after general anaesthesia administered via a…
- Trial name
- NCT04644900
- Testing
- chewed mint gum, Mouthwash
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Fudan University
Hernia, Inguinal
Transinguinal Periperitoneal Technique in Inguinal Hernioplasty
evaluation of feasibility and efficacy of trans inguinal periperitoneal technique by using conventional mesh inguinal hernia repair in general surgery department in Assiut university hospitals
- Trial name
- NCT06270472
- Testing
- hernioplasty
- Volunteers
- 20 people
- Sponsor
- Assiut University
Heart Chambers
Comparing Cardiac Chamber Measurements: TTE vs. TEE Under Anesthesia
This study aims to compare two common ultrasound techniques used during heart surgery: transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE).
- Trial name
- CM-TTE-TEE (NCT06715371)
- Testing
- Transthoracic Echocardiography (TTE) and Transesophageal Echocardiography (TEE)
- Where
- Canada
- Volunteers
- 114 people
- Sponsor
- Sunnybrook Health Sciences Centre
Postoperative Pain, Pain Management
Patients' Perceptions of Postoperative Analgesic Monitoring in Elective General Surgery
This study examines how patients perceive postoperative analgesic monitoring during routine care in elective general surgery. Postoperative pain monitoring is a standard nursing practice, but patients may experience it as either…
- Trial name
- PSAM-SEM (NCT07389330)
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 312 people
- Sponsor
- Agri Ibrahim Cecen University
Frail Elderly Syndrome, Emergencies
Frailty and Sarcopenia Outcomes in Emergency General Surgery
1. A retrospective scoping cohort review of adult patients undergoing emergency laparotomy/laparoscopy for acute gastrointestinal (GI) pathology who have had a CT scan of the abdomen(+/- pelvis).
- Conditions
- Frail Elderly Syndrome, Emergencies, Surgery, Sarcopenia
- Trial name
- FrOGS (NCT03534765)
- Testing
- CT abdomen +/- pelvis, Edmunton Frailty Score, Emergency laparotomy for general surgical pathology
- Where
- 10 sites in United Kingdom
- Volunteers
- 294 people
- Sponsor
- Yeovil District Hospital NHS Foundation Trust
Endotracheal Extubation, Airway Anesthesia
BELUGA: Better to Exchange ETT for LMA Before Extubation in Children Under General Anaesthesia
During surgery, anaesthetists can use an endotracheal tube (ETT) to facilitate ventilation. At emergence from general anaesthesia, there are two techniques for removal of the ETT: (1) the ETT is removed when the child is waking…
- Conditions
- Endotracheal Extubation, Airway Anesthesia, Paediatric
- Trial name
- BELUGA (NCT07204990)
- Testing
- Direct removal of endotracheal tube, Laryngeal mask airway inserted following deep extubation
- Where
- 8 sites in United States, Australia and 4 more
- Volunteers
- 1,400 people
- Sponsor
- Telethon Kids Institute
Intubation
First Attempt Intubation Rate With Airtraq vs Macintosh Direct Laryngoscope
In recent decades, numerous videolaryngoscopes have been introduced to facilitate tracheal intubation. However, it remains unclear whether videolaryngoscope will increase the successful tracheal intubation compared with usual…
- Trial name
- FAIRAiM (NCT03887897)
- Testing
- Tracheal Intubation
- Where
- Hong Kong
- Volunteers
- 1,586 people
- Sponsor
- Chinese University of Hong Kong
Generalized Chronic Periodontitis
Erbium Chromium: YSGG Laser Effect on Surgical Treatment of Chronic Periodontitis
Microbiological and Clinical assessment of Er,Cr:YSGG laser in conjunction to open flap debridement (OFD) in treatment of chronic periodontitis through real time PCR assay for quantification of total bacterial load.
- Trial name
- NCT03810560
- Testing
- laser device Er,Cr:YSGG laser
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- alaa
Strabismus
The Effect of Povidone-iodine Ophthalmic Surgical Prep Solution on Respiration in Children Undergoing Strabismus Surgery With General Anesthesia.
Determine whether the application of povidone-iodine ophthalmic solution onto the ocular surface causes a change in respiration in children undergoing strabismus surgery with general anesthesia.
- Trial name
- NCT03349515
- Testing
- Provodine-Iodine Solution, Group B will receive three drops in each eye of ophthalmic balanced salt solution.
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Pregnancy, Cesarean Delivery
Pharmacogenetics of Remifentanil in Patients With Hypertension Undergoing Cesarean Delivery Under General Anesthesia
Caesarean delivery under general anaesthesia (GA) carries nowadays still 25% risk of insufficient depth of anaesthesia in a time before the fetus delivery. The reason is the lack of opioid administration.
- Conditions
- Pregnancy, Cesarean Delivery, General Anesthesia
- Trial name
- NCT01550640
- Testing
- Remifentanil
- Where
- Czechia
- Volunteers
- 149 people
- Sponsor
- Charles University, Czech Republic
Aggressive Periodontitis, Generalized, Periodontal Health
GCF HIF-1α, VEGF and TNF-α Levels in G-AgP Patients Before and After Periodontal Treatment.
Hypoxia-inducible angiogenic pathway involving hypoxia inducible factor-1 alpha (HIF-1α), vascular endothelial growth factor (VEGF) and tumour necrosis factor- alpha (TNF-α) may regulate the several biological processes related…
- Trial name
- NCT04020315
- Testing
- Non-surgically performed scaling and root planing
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Vitrectomy Operation Under General Anesthesia
Comparison Between Propofol-remifentanil Total Intravenous Anesthesia and Desflurane-remifentanil Balanced Anesthesia With Regard to Post-anesthetic Functional Recovery Measured With QoR-40 in Vitrectomy
Total intravenous anesthesia (TIVA) and inhalation anesthesia are both widely and safely used, and there are many clinical trials comparing these on various aspects of anesthesia.
- Trial name
- NCT02212340
- Testing
- fresofol and remifentanil, desflurane and remifentanil
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Yonsei University
In-hospital Mortality
Association Between Administration of Dexmedetomidine and Postoperative Mortality in Hospitals
The present multicentre retrospective cohort study aimed to investigate the association between intraoperative administration of dexmedetomidine and postoperative mortality in hospitals.
- Trial name
- NCT06248346
- Testing
- Dexmedetomidine
- Volunteers
- 518,043 people
- Sponsor
- Xijing Hospital
Oropharyngeal Leak Pressure
The Effects of GMA-TULIP, I-gel, and BlockBuster Laryngeal Mask in Surgeries With Lateral Position Under General Anesthesia
To compare the efficacy and safety of traditional inflatable laryngeal mask, i-gel non-inflatable laryngeal mask and GMA-TULIP non-inflatable laryngeal mask in surgeries with lateral position under general anesthesia, so that…
- Trial name
- NCT06782841
- Testing
- GMA-TULIP Laryngeal Mask, i-gel Laryngeal Mask, BlockBuster Laryngeal Mask
- Where
- China
- Volunteers
- 102 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.