Clinical trials: Global Surgery
Surgery, Anesthesia Intubation Complication
MAsk VEntilation With Paratracheal Pressure In Children. Para Tracheal Compression to Prevent Gastric Insufflation in Children
The use of cricoid pressure to prevent gastric aspiration or regurgitation in case of "full stomach" situation or emergency is still controversial in the adult population.
- Trial name
- MAVEPPIC (NCT05279170)
- Testing
- MAVEPPIC: MAsk VEntilation with Paratracheal Pressure In Children
- Where
- 2 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Lille
Anesthesia, Cognitive Dysfunction
Evaluation of Cognitive Functions by Cerebral Pulse Oximetry
General and Spinal Anesthesia can be used in geriatric patients in orthopedic surgery. Post-op cognitive dysfunction can be seen in orthopedic surgeries in this group of patients.
- Trial name
- NCT03827083
- Testing
- cerebral pulse oximetry
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Global Surgery, Medical Missions
From Short-term Surgical Missions Towards Sustainable Partnerships
Introduction: Recently, the devastating consequences of neglected surgical care in global health became apparent with an estimated five billion people lacking access to safe surgical and anesthesia care.
- Trial name
- NCT04450823
- Testing
- no intervention
- Where
- Netherlands
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Global Surgery Amsterdam
Low Cardiac Output Syndrome After Adult Cardiac Surgery
Peak Systolic Global Longitudinal Strain and Low Cardiac Output Syndrome After Cardiac Surgery
This is a retrospective observational study to assess the relationship between peak systolic global longitudinal strain measured on pre-cardiopulmonary bypass trans-esophageal echo images predicts post-operative low cardiac…
- Trial name
- NCT02771080
- Testing
- Cardiac surgery
- Volunteers
- 275 people
- Sponsor
- University of Liege
Nutrition Assessment, Nutritional Support
The Effect of Perioperative Nutritional Assessment and Nutritional Support on Clinical Outcomes
It is a study to evaluate the relationship between preoperative nutritional assessment and clinical outcomes and to explore the effect of preoperative nutritional support on clinical outcomes in patients after abdominal operation.
- Conditions
- Nutrition Assessment, Nutritional Support, Clinical Outcomes, General Surgery
- Trial name
- PNAS (NCT03115931)
- Testing
- no intervention
- Where
- China
- Volunteers
- 4,880 people
- Sponsor
- Jinling Hospital, China
Surgery, Anesthesia
Surgical Capacity in Zimbabwean Public Hospitals
This study aimed to understand how ready Zimbabwe's public hospitals are to perform essential surgeries, which are critical for treating a wide range of health issues from emergencies like car accidents to planned procedures such…
- Trial name
- NCT06358183
- Testing
- No intervention
- Where
- Zimbabwe
- Volunteers
- 80 people
- Sponsor
- Parirenyatwa Hospital
Postoperative Complication, Cognitive Retention Disorder
Methylprednisolone Combined Electric-acupuncture on Cognitive Function
Postoperative cognitive dysfunction (POCD) refers to the patients in the central nervous system complications after general anesthesia and clinical manifestations of mental disorder, anxiety, personality changes, impaired memory…
- Trial name
- NCT02535039
- Testing
- Methylprednisolone, Physiological saline
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
COVID-19, Emergency General Surgery
Outcomes in Emergency Laparotomies During COVID-19 Pandemic
NLR has previously been observed to correlate with complications in upper GI (1) and colorectal (2) surgery. The investigators sought to assess if a similar correlation can be identified in emergency general surgical patients and…
- Trial name
- NCT04419571
- Testing
- Emergency Laparotomy
- Where
- United Kingdom
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Barking, Havering and Redbridge University Hospitals NHS Trust
Postoperative Delirium, Elective Non-Cardiac Surgery
Correlation Between Blood Biomarkers and Postoperative Delirium in Elective Non-Cardiac Surgery.
More than 20% of patients over 60 years old develop postoperative delirium following non-cardiac surgery . Delirium increases morbidity and mortality , and may lead to long-term cognitive impairment .
- Trial name
- NCT03915314
- Testing
- Neuropsychological tests
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Xuzhou Medical University
Postoperative Pain, Postoperative Nausea and Vomiting
Effectiveness of Low-Dose Ketamine and Intravenous Lidocaine Versus Fentanyl for Postoperative Pain
Background: Rational approaches to perioperative patient management have been used to meet intraoperative analgesic needs and avoid opioid-related adverse effects.
- Trial name
- Vs(versus) (NCT07213687)
- Testing
- Low dose intravenous ketamine
- Where
- Ethiopia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dilla University
Anesthesia of Mucous Membrane
The Effect of Bilateral Sphenopalatine Ganglion Block on Postoperative Pain in Patients to be Subject to Septorhinoplasty Surgery
The aim of this study is to examine the effects of bilateral sphenopalatine ganglion block on surgical conditions, hemodynamics, intraoperative and postoperative analgesic use, recovery characteristics, and postoperative pain…
- Trial name
- NCT06016816
- Testing
- Bilateral endoscopic sphenopalatine ganglion block
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Quality of Life (QOL), Decision Making
Peri-Operative Surgical Care Optimisation for Patients Requiring Emergency Surgery
Emergency General Surgery (EGS) is an umbrella term which describes all patients presenting to hospital with an acute abdominal problem. Patients can have various conditions requiring emergency operations.
- Conditions
- Quality of Life (QOL), Decision Making, Emergency General Surgery
- Trial name
- PERI-SCOPES (NCT06972017)
- Volunteers
- 112 people
- Sponsor
- NHS Greater Glasgow and Clyde
Supraglottic Airway Devices
Respiration and The Airway With Laryngeal Masks
Baska® mask (Proact Medical Systems, Frenchs Forest NSW, Australia) is displayed in figure 1 which is the latest addition to an array of supra-glottic airway devices in clinical use.
- Trial name
- NCT03542890
- Testing
- Baska Mask, I-gel
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Reham Ali Abdelhaleem Abdelrahman
Anesthesia; Reaction, Adverse Effect of Other General Anesthetics
Influence of Anesthesia Technique on Postoperative Evolution After Urogenital Surgical Interventions
The study hypothesis is that regional anesthesia offers better outcome for the patients who underwent robot assisted laparoscopic urogenital surgery.
- Conditions
- Anesthesia; Reaction, Adverse Effect of Other General Anesthetics, Adverse Anesthesia Outcome, Acute Kidney Injury
- Trial name
- ROBOTNGAL (NCT01898897)
- Testing
- epidural catheter insertion, robot assisted laparoscopic urogenital surgery
- Where
- Romania
- Volunteers
- 60 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Gingival Recession, Generalized
Cor Adv Flap Plus Ac Derm Matrix in Thin Phenotype Multiple Recessions
Clinical evaluation of conventional and modified coronally advanced flaps combined with acellular dermal matrix graft
- Trial name
- NCT03883438
- Testing
- Modified coronally advanced flap and acellular dermal matrix graft
- Where
- 4 sites in Azerbaijan, Brazil and 2 more
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Aziz Aliyev Azerbaijan State Advanced Training Institute for Doctors
Intraoperative Neurophysiological Monitoring, Malignant Brain Tumors
Intraoperative Neurophysiological Monitoring in Brain Tumor Surgery: Prospective Cohort Studies
BACKGROUND Brain tumor surgery requires balancing two competing priorities: maximizing the extent of tumor resection to improve survival while preserving neurological function.
- Conditions
- Intraoperative Neurophysiological Monitoring, Malignant Brain Tumors, Motor Evoked Potential Monitoring, Cortico-cortical Evoked Potential Monitoring
- Trial name
- NCT07789938
- Testing
- Intraoperative neurophysiological monitoring, no Intraoperative neurophysiological monitoring
- Where
- Denmark
- Volunteers
- 166 people
- Sponsor
- Odense University Hospital
Hysterectomy (MeSH nr: E04.950.300.399)
Transforming Global Surgery Capacity and Capability Through Affordable Virtual Reality
The goal of this randomized controlled trial was to evaluate whether Deliberate Virtual Reality (VR) training can improve surgical skills, knowledge, and confidence in performing postpartum hysterectomy among junior-level Zambian…
- Trial name
- NCT07403526
- Testing
- Deliberate Virtual Reality (VR) Training, Standard Clinical Training
- Where
- Zambia
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Southern Methodist University
Post Surgical Pat., Medical Pat., Resp. Failure, Car.Arrest, Death
Evaluation of EverOn™ - A Contact-Free System for Measuring Heart Rate, Respiratory Rate and Motion
Evaluation of continuous monitoring device on patients Risk during hospitalization and nurse satisfaction level.
- Trial name
- NCT00875602
- Testing
- EverOn (EarlySense) contactless monitoring device
- Where
- United States
- Sponsor
- EarlySense Ltd.
Hysteroscopy, Ambulatory Surgery
Remimazolam-Flumazenil Versus Sevoflurane for Hysteroscopic Day Surgery
This prospective, single-center, randomized controlled trial aims to compare remimazolam anesthesia with planned flumazenil reversal and sevoflurane-based balanced anesthesia in adult women undergoing ambulatory hysteroscopic…
- Conditions
- Hysteroscopy, Ambulatory Surgery, General Anesthesia
- Trial name
- NCT07663877
- Testing
- Remimazolam, Flumazenil, Sevoflurane
- Where
- South Korea
- Volunteers
- 124 people
- Sponsor
- Chung-Ang University Gwangmyeong Hospital
Liver Diseases
The Orange-III Trial: Optimised Recovery With Movicol® Preoperatively Within an Enhanced Recovery Programme
The aim of this study is to accelerate recovery after liver surgery by enhancing intestinal passage through the preoperative use of Movicol.
- Trial name
- NCT01429779
- Testing
- Movicol
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 80 people
- Sponsor
- Maastricht University Medical Center
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