Clinical trials: Global Surgery
Arthrosis; Spine, Spinal Stenosis Lumbar
Lumbar Stabilization Exercises in Adult Patients With Lumbar Arthrodesis Surgery
The purpose of this study is to determine which type of lumbar stabilization exercise is more effective to improve functionality and reduce pain in patients operated with lumbar arthrodesis, to guide clinical practice in the…
- Trial name
- NCT03538093
- Testing
- Experimental: Local Stabilization Exercise, Experimental: Global Stabilization Exercise, Experimental: Mixed Stabilization Exercise
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- University of Chile
Surgery
Improving Surgeon Performance Measures for Robot-Assisted Surgery
The purpose of this study is to develop new tools to understand surgeon performance to improve surgical training and participant outcomes after surgery.
- Trial name
- NCT06037837
- Testing
- Robotic Surgery
- Where
- 7 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cerebral Hypoxia
Feasibility Trial to Maintain Normal Cerebral Oxygen Saturation in High-Risk Cardiac Surgery
Using the brain and the heart as index organs, perioperative interventions to optimize cerebral oxygen saturation and cardiac contractility in high-risk patients undergoing cardiac surgery should have a beneficial systemic effect…
- Trial name
- Tête-à-coeur (NCT01432184)
- Testing
- strategies to reverse decrease in rSO2
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Montreal Heart Institute
Postoperative Pain Relief
Bilateral Thorathic Erector Spinae Plane Block in Laparoscopic Bariatic Surgeries
The study is to evaluate effectiveness of one-level versus two-level thoracic ESP block on intraoperative and postoperative analgesia in bariatric surgeries and to compare total opioid consumption of both groups.
- Trial name
- ESPBbariatrics (NCT06812364)
- Testing
- one level ESPB, two level ESPB
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Cairo University
Hypoxia
Effect of Different Positions During Extubation on Incidence of Hypoxemia in the Peri Extubation Period
Pediatric Obstructive Sleep Apnea Syndrome (OSAS) is common, often due to enlarged tonsils/adenoids. Tonsillectomy/adenoidectomy frequently performed under GA with tracheal intubation due to the age of children.
- Trial name
- NCT07231887
- Testing
- positioning during peri-extubation
- Volunteers
- 262 people
- Sponsor
- Assiut University
Breast Cancer
Effect of Midazolam Premedication Before Induction on the Functional Recovery After General Anesthesia in the Patients Undergoing Breast Surgery Due to Breast Cancer
Normally, higher levels of preoperational stress or anxiety affect behavior and recovery after the operation. Moreover, patients undergoing mastectomy are usually young women, and this demographic is known to experience higher…
- Trial name
- NCT01945476
- Testing
- midazolam premedication
- Where
- South Korea
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Spine Fusion, Spine Metastases
Erector Spinae Plane Block in Spine Surgeries for Postoperative Pain
This prospective single-blind randomized controlled study on 50 patients between 18 and 65 years, both sexes, with ASA I-II and undergoing elective lumbar spine surgical procedures.
- Conditions
- Spine Fusion, Spine Metastases, Postoperative Pain
- Trial name
- NCT06970704
- Testing
- Erector Spinae Plane Block using 0.25 % bupivacaine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Urogenital Diseases, Nerve Block
Comparison of the Efficacy of Sacral Espb and Caudal Block for Pain Management After Urogenital Surgeries in Children
The aim of this study was to compare the efficacy of caudal block and sacral espb used as a postoperative analgesia method in urogenital pediatric surgery cases.
- Conditions
- Urogenital Diseases, Nerve Block, Pain, Postoperative
- Trial name
- SESPB (NCT06373185)
- Testing
- Ultrasound-guided sacral erector spinae plane block, Ultrasound-guided caudal block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Giresun University
Adverse Effect of Other General Anesthetics
The Effects of Remifentanil and Remifentanil-Alfentanil Administration in Children
Sevoflurane is widely and frequently used in pediatric anesthesia due to its non-irritating airway properties, rapid induction and emergence. However, it is associated with emergence agitation (EA) in children.
- Trial name
- NCT02486926
- Testing
- Sevoflurane, Remifentanil, Alfentanil
- Volunteers
- 102 people
- Sponsor
- Hallym University Medical Center
Abdomen, Acute
Clinical Outcomes and Equality in Healthcare for Emergency General Surgery Patients Undergoing Emergency Laparotomy
The goal of this observational cohort study is to evaluate the standard of care for general surgerical patients undergoing emergency laparotomy and assess factors affecting clinical outcomes, as well as evaluating the quality of…
- Trial name
- LAPTOP (NCT05623176)
- Testing
- Standardised laparotomy care
- Where
- Sweden
- Volunteers
- 2,000 people
- Sponsor
- Region Stockholm
Analgesia
Evaluation of Surgical Stress Index (SSI) During Sevoflurane/Remifentanil Anesthesia
The aim of the present prospective randomized study was to challenge the ability of SSI to detect painful stimulation during sevoflurane - remifentanil anesthesia.
- Trial name
- NCT00791791
- Testing
- standardized pain stimulus
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University Hospital Schleswig-Holstein
Laparoscopic Gynecologic, Abdominal, Other Surgery, General Anesthesia
Therapeutic Efficacy and Safety of Palonosetron in Treatment of Postoperative Nausea and Vomiting
This study was designed to evaluate the treatment efficacy and safety of palonosetron for the patients who undergo laparoscopic gynecologic, abdominal or other surgery under general anesthesia.
- Trial name
- NCT01568268
- Testing
- Palonosetron
- Where
- 4 sites in South Korea
- Volunteers
- 384 people
- Sponsor
- Samsung Medical Center
Large Bowel Cancer
Effects of Different Strategy of Fluids Administration on Acid/Base Disorders and Inflammatory Mediators
Aim of the study is to ascertain whether a different strategy of fluids administration can be responsible of differences in terms of acid/base disorders (Stewart approach), pro-inflammatory and inflammatory mediators.
- Trial name
- NCT01320891
- Testing
- balanced solutions, not balanced
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Università degli Studi di Ferrara
Gynecologic Surgery, General Anesthesia
Long-term Follow-up of Bio-signals and Quality of Recovery Following Implementation of ERAS
The goal of this clinical trial is to evaluate the effect of an Enhanced Recovery After Surgery(ERAS) protocol in patients undergoing gynecologic laparoscopic surgery under general anesthesia.
- Trial name
- NCT07146178
- Testing
- Enhanced Recovery After Surgery, Usual Care
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Wonju Severance Christian Hospital
Intensive Care, Surgical
Postoperative Delirium in Adult Patients After Elective Craniotomy Under General Anaesthesia
Postoperative delirium may result in many adverse complications. At present little is known about postoperative delirium in patients after crniotomy because they may manifest similar symptoms to definitely delirium for some…
- Conditions
- Intensive Care, Surgical, Postoperative Care, Neurosurgery
- Trial name
- NCT03087838
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Capital Medical University
Anesthesia, General
Safety and Efficacy of Sugammadex (Org 25969, MK-8616) in Participants With or Having a Past History of Pulmonary Disease (19.4.308) (P05932) (MK-8616-017)
The purpose of the trial is to research the safety and to show faster recovery after administration of 2.0 mg/kg or 4.0 mg/kg sugammadex (Org 25969, MK-8616) given as a reversal agent for 0.6 mg/kg (0.15 mg/kg maintenance dose)…
- Trial name
- NCT00475215
- Testing
- Sugammadex, Rocuronium
- Volunteers
- 86 people
- Sponsor
- Merck Sharp & Dohme LLC
Cleft Palate
Suprazygomatic Block in Cleft Palate Surgery in Children
Cleft palate (CP) is a common congenital malformation, with an incidence ranging from 0.1 to 1.1 per 1000 births depending on the population group (liau et al, 2010).
- Trial name
- NCT03412474
- Testing
- Bupivacaine, Dexmedetomidine, paracetamol
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Pain
Analgesia Nociception Index in Orthognathic Surgery
This study aims to determine whether goal-directed analgesia using ANI(Analgesia/Nociception Index) can improve the quality of postoperative recovery in patients undergoing maxillofacial surgery.
- Trial name
- NCT06205355
- Testing
- Analgesia/Nociception Index (ANI) monitoring, Standard monitoring
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Hospital
Supraglottic Airway Devices
Respiration and The Airway With Laryngeal Masks
Baska® mask (Proact Medical Systems, Frenchs Forest NSW, Australia) is displayed in figure 1 which is the latest addition to an array of supra-glottic airway devices in clinical use.
- Trial name
- NCT03542890
- Testing
- Baska Mask, I-gel
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Reham Ali Abdelhaleem Abdelrahman
Difficult / Failed Intubation
NC/TMD Ratio As a Difficult Airway Predictor in Obese Patients
To assess accuracy of NC/TM distance ratio in terms of sensitivity, specificity, negative predictive value (NPV) and positive predictive value (PPV) for predicting difficult intubation in obese patient with Intubation difficulty…
- Trial name
- NCT05735106
- Where
- Pakistan
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- KRL Hospital, Islamabad
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