Clinical trials: Global Surgery
Frailty, Perioperative/Postoperative Complications
Correlation of Preoperative Global Olfactory Function With Frailty, Perioperative Neurocognitive Disorders and Mortality
The aims of this research project are to evaluate whether global olfactory impairment is a reliable indicator of preoperative frailty and cognitive impairment, and whether it may predict postoperative neurocognitive disorders…
- Conditions
- Frailty, Perioperative/Postoperative Complications, Olfactory Disorder, Neurocognitive Disorders
- Trial name
- NCT04761458
- Testing
- Olfactory function testing, Edmonton Frail Scale, Clinical Frailty Scale
- Where
- Belgium
- Volunteers
- 215 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Lumbar Disc Herniation, Spinal Surgery
Comparison of 5 vs 8 cmH₂O PEEP on Respiratory Mechanics in Prone Lumbar Surgery
This randomized controlled clinical trial aims to compare the effects of two different positive end-expiratory pressure (PEEP) levels (5 cmH₂O and 8 cmH₂O) on respiratory mechanics in patients undergoing lumbar spine surgery in…
- Conditions
- Lumbar Disc Herniation, Spinal Surgery, Prone Position, General Anesthesia
- Trial name
- PROPEEP (NCT07545733)
- Testing
- Mechanical Ventilation (PEEP)
- Volunteers
- 60 people
- Sponsor
- Harran University
Adult Spinal Deformity, Wireless Continuous Vital Signs Monitoring
Feasibility of Wireless Continuous Vital Sign Monitoring and Impact on Patients Undergoing Adult Spinal Surgery in a General Ward
The goal of this feasibility study is to explore the use of wireless continuous vital sign monitoring in an orthopaedic setting among orthopaedic nurses and patients undergoing adult spinal deformity surgery.
- Conditions
- Adult Spinal Deformity, Wireless Continuous Vital Signs Monitoring, Wireless Vital Signs Monitoring System, Acceptability
- Trial name
- NCT07105189
- Testing
- Wireless monitoring
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Breast Cancer
Paravertebral Block, an Adjunct to General Anaesthesia for Breast Surgery?
Aim is to study if a paravertebral block as an adjunct to general anesthesia is a suitable technique for extended, one sided, breast surgery.
- Trial name
- NCT00547989
- Testing
- standard anaesthesia (bupivacaine), additional pvb (ropivacaine) and elastomeric disposable infusion pump, additional pvb (ropivacaine)
- Where
- Netherlands
- Volunteers
- 46 people
- Sponsor
- Maastricht University Medical Center
Neuromuscular Blockade
Safety and Efficacy of HRS-9190 Compared to Rocuronium for Bolus Maintenance in Adults
The study will enroll adult patients scheduled for elective surgery requiring general anesthesia. Participants will be randomly assigned to receive either HRS-9190 for Injection or Rocuronium.
- Trial name
- NCT07404579
- Testing
- HRS-9190, Rocuronium
- Where
- 2 sites in China
- Volunteers
- 103 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Preventing Hypothermia, Perioperative Hypothermia
The Effect of Preoperative Warming on Postoperative Hypothermia
36 patients American society of anesthesiology (ASA) physical status I,II and III undergoing general anesthesia for elective transurethral resection of the prostate (TUR-P) surgery will be included in the study.
- Trial name
- NCT01858727
- Testing
- forced air warming group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ankara Diskapi Training and Research Hospital
Colorectal Surgery, Surgical Wound Infection
A Study of an Antibiotic Implant in General Surgical Subjects at Higher Risk for Surgical Wound Infection
The purpose of this study is to determine whether the gentamicin-collagen sponge is safe and effective for preventing surgical wound infections in patients undergoing colorectal surgery.
- Trial name
- NCT00600925
- Testing
- gentamicin-collagen sponge dipped in saline
- Where
- 39 sites in United States
- Volunteers
- 602 people
- Sponsor
- Innocoll
General Anesthesia, Elective Surgery
Effect of Pre-injection of Rocuronium on Neuromuscular Blockade Onset Time and Hemodynamics During General Anesthesia Induction
This is a single-center, prospective, randomized, controlled trial comparing pre-injection versus standard bolus administration of rocuronium bromide for general anesthesia induction.
- Trial name
- NCT07716891
- Testing
- Rocuronium Bromide (Pretreatment Injection), Rocuronium Bromide (Conventional Injection)
- Where
- China
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Postoperative Complications, Postoperative Wound Infection
Influence of Deep Versus Moderate Neuromuscular Blockade During General Anesthesia on 30-day Readmission Rates
Deep neuromuscular block (NMB) has shown to produce superior surgical conditions during various abdominal and non abdominal surgeries.
- Conditions
- Postoperative Complications, Postoperative Wound Infection, Pneumonia
- Trial name
- NCT03174223
- Testing
- deep neuromuscular block
- Where
- Netherlands
- Volunteers
- 460 people
- Sponsor
- Leiden University Medical Center
Delirium, Postoperative
Perioperative Risk Factors for Postoperative Delirium in Children
Despite recent advances in postoperative delirium research, the proportion of children with postoperative delirium is still high.
- Trial name
- NCT01032161
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Huazhong University of Science and Technology
Drug Use
Regional Nasal Block and Dexmedetomidine in Endoscopic Sinus Surgery
The purpose is to compare the efficacy of combined regional nasal block and general anesthesia versus general anesthesia with dexmedetomidine during endoscopic sinus surgery in optimizing intraoperative surgical field.
- Trial name
- NCT05361642
- Testing
- Bupivacaine HCl 0.5% Injectable Solution, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Smoking and POCD
The Effect of Heavy Smoking on Early Post Operative Cognitive Dysfunction in Senile Patients .
Cognitive dysfunction is the impairment of mental process of perception, memory and information processing which allow the human to acquire knowledge and plan for the future .
- Trial name
- NCT05782946
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Beni-Suef University
General Surgery, Geriatrics
Frailty and Postoperative Outcomes After Emergency General Surgery
The investigators will examine the association between preoperative frailty and postoperative outcomes and resource utilization after emergency general surgery.
- Conditions
- General Surgery, Geriatrics, Outcomes Research
- Trial name
- NCT02835053
- Testing
- Frailty
- Where
- Canada
- Volunteers
- 150,000 people
- Sponsor
- Ottawa Hospital Research Institute
Infant Apnea, Surgical Procedure, Unspecified
Apneic Oxygénation by Nasal Canula During Infants Airway Management Study
This is a randomized clinical trial investigating the utility of apneic oxygenation via high flow nasal cannulae during airway management for infants general anaesthesia.
- Conditions
- Infant Apnea, Surgical Procedure, Unspecified, Airway Management
- Trial name
- Oxyeno (NCT03967769)
- Testing
- High Flow nasal Cannula
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Clermont-Ferrand
Bispectral Index Variability During General Anesthesia and Postoperative Recovery, Cholecystectomy, Laparoscopic
BIS Variability and Change in Quality of Recovery After Surgery
This prospective observational study aims to examine the relationship between fluctuations in anesthesia depth, measured by bispectral index (BIS) monitoring during surgery, and changes in patients' postoperative recovery…
- Trial name
- NCT07454629
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Sakarya University
General Anesthesia
One-year Mortality After Surgery and Low Bispectral Index
A correlation between deep anesthesia (defined as time with Bispectral Index (BIS) lower than 45) and death within 1 yr after surgery has previously been reported.
- Trial name
- ELA (NCT01198639)
- Testing
- manual administration of iv anesthetics (propofol and remifentanil) using the Toolbox platform, closed-loop administration of iv anesthetics (propofol and remifentanil) using the Toolbox platform
- Where
- 22 sites in France
- Volunteers
- 2,044 people
- Sponsor
- Hopital Foch
Elderly Patients Undergoing Elective Non-cardiac Surgery
Ultrasound of the Inferior Vena Cava in the Prevention of Hypotension After Induction of General Anesthesia
Based on the preoperative ultrasound detection of various parametric indicators of the inferior vena cava cross-section, including the ratio of the inferior vena cava's long and short axes, cross-sectional area and circumference…
- Trial name
- NCT06530901
- Testing
- Multidimensional ultrasound of the inferior vena cava
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhuan Zhang
Colorectal Cancer, Esophageal Cancer
Clinical Trial Protocol for Evaluating the Efficacy and Safety of Thoracoabdominal Endoscopic Surgery System in Remote Laparoscopic Surgery for Urology, General Surgery, Gynecology and Thoracic Surgery
Evaluation of the Efficacy and Safety of the Thoracoabdominal Endoscopic Surgery System Produced by Shenzhen Cornerstone Robotics Technology Co., Ltd.
- Conditions
- Colorectal Cancer, Esophageal Cancer, Hepatectomy, Radical Hysterectomy
- Trial name
- NCT07382635
- Testing
- Robot-assisted surgery
- Volunteers
- 98 people
- Sponsor
- Cornerstone Robotics
Gynecology, Postoperative Recovery
Correlation Between Physical Fitness Status and Quality of Postoperative Recovery in Gynaecological ERAS Patients
Investigate the current status of perioperative physical fitness.To compare the degree of agreement between the 6-minute walk test and the EQ5D5L-VAS score in assessing recovery after gynecological ERAS, and to provide a…
- Conditions
- Gynecology, Postoperative Recovery, Enhanced Recovery After Surgery, Six-minute Walk Test
- Trial name
- NCT06704750
- Testing
- 6-minute walk test
- Where
- China
- Volunteers
- 146 people
- Sponsor
- Peking Union Medical College Hospital
Ultrasonography, Airway Management
Evaluation of Anterior Neck Ultrasound in Predicting Difficult Airway in Obese Patients
Obese patients are at increased risk of difficult airway management due to anatomical changes in the anterior neck soft tissues.
- Conditions
- Ultrasonography, Airway Management, Intubation, Intratracheal, Obesity and Overweight
- Trial name
- NCT07346768
- Testing
- None (Observational study)
- Volunteers
- 52 people
- Sponsor
- Gaziantep City Hospital
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