Clinical trials: Global Surgery
Anesthesia, General
The Effect of BIS-guided Propofol Induction on Hemodynamic Response in Patients With Cardiac Risk.
Anesthesia induction will be started by monitoring ECG, non-invasive artery monitoring, peripheral oxygen saturation and BIS for all patients who are taken to the operating room without sedation.
- Trial name
- NCT04729465
- Testing
- Propofol, Bispectral Index Monitor
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Head and Neck Neoplasm
Preoxygenation With a High-flow Nasal Cannula or a Simple Mask Before General Anesthesia in Head and Neck Surgery
Objectives: To assess arterial oxygen partial pressure (PaO2) at defined time points during the preoxygenation and to compare between high flow heated humidified nasal oxygen versus standard preoxygenation with oxygen insufflation…
- Trial name
- NCT03896906
- Testing
- High-flow nasal cannula, simple mask
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Asan Medical Center
Intestinal Obstruction, Digestive System Surgical Procedures
Seprafilm in the Reduction of Incidence of Bowel Obstruction in General Surgery
The purpose of the study is to evaluate the efficacy of Seprafilm in reducing the incidence of bowel obstruction and to evaluate the incidence of all serious adverse events (SAEs) associated with the use of Seprafilm occurring…
- Trial name
- NCT00130715
- Testing
- Seprafilm Bioresorbable Membrane
- Where
- 21 sites in United States, Canada and 3 more
- Sponsor
- Genzyme, a Sanofi Company
Arthroplasty, Replacement, Hip, Knee
Enhanced Recovery After Surgery (ERAS) Pathway for Primary Hip and Knee Arthroplasty
As the world goes into the aging society, the number of total hip and total knee arthroplasty (THA and TKA) will increase fast. It's important to develop strategies to improve the quality of healthcare and get earlier recovery…
- Trial name
- NCT03517098
- Testing
- The ERAS group, The non-ERAS group
- Where
- China
- Volunteers
- 640 people
- Sponsor
- West China Hospital
Shoulder Surgery
Modeling the Effect of EtCO2 on Cerebral Oxygenation
The aim of this study was to investigate the relationship between the end-tidal carbon dioxide (EtCO2) and cerebral oxygen saturation (rSO2) and to identify the covariates in the pharmacodynamic relationship between EtCO2 and…
- Trial name
- NCT02284763
- Testing
- EtCO2
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Severance Hospital
Cognitive Dysfunction
Effects of Dexmedetomidine on Cognitive Outcome and Brain Injury Markers
Dexmedetomidine is a drug with sedative, anxiolytic, and analgesic properties. Benefits of its use covers good sedations without respiratory suppression, reduced circulating catecholamines due to decreased sympathetic…
- Trial name
- NCT03585452
- Testing
- Dexmedetomidine Infusion, Propofol based general anesthesia
- Where
- Poland
- Volunteers
- 23 people
- Sponsor
- Michał Kowalczyk
Total Knee Replacement Surgery
Postoperative Pain in Total Knee Arthroplasty: a Comparison Between General and Spinal Anesthesia
Total knee arthroplasty may be conducted either under general anesthesia or spinal block. previous studies have shown that spinal block leads to less complications.
- Trial name
- NCT03176758
- Testing
- Spinal Block, General anesthetic, Total knee replacement
- Volunteers
- 60 people
- Sponsor
- Meir Medical Center
General Surgery, Costs and Cost Analysis
Evaluating the Impact of the National Health Insurance Scheme of Ghana on Surgical Care
Ghana, a Low-Middle Income Country (LMIC) situated in the heart of West Africa started a national health insurance scheme in 2003.The scheme was designed to provide a comprehensive benefit package inclusive of surgical care and…
- Trial name
- NCT03604458
- Where
- Ghana
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Monitored Anesthesia Care, Cardiac Surgery
Monitored Anesthesia Care Versus Intubated General Anesthesia for Open Heart Surgery Under Cardiopulmonary Bypass
Though Cardiac surgery under cardiopulmonary bypass (CPB) under epidural anesthesia in conscious patients is associated with increased risk of epidural hematoma.
- Conditions
- Monitored Anesthesia Care, Cardiac Surgery, Postoperative Recovery
- Trial name
- NCT05011617
- Testing
- Non-intubation and monitoring anesthesia care (MAC)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- ShuGuang Hospital
Pediatric Disorder
Comparing the Difference in Pain Control in the Pediatric General Surgery Population: to Alternate or Combine Acetaminophen and Ibuprofen?
To examine the difference in pain control in the pediatric general surgery population alternating acetaminophen and Ibuprofen q 3 hours vs giving them simultaneous combination therapy around the clock.
- Trial name
- NCT06505148
- Testing
- Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Baylor Research Institute
Respiratory Complication, Respiration, Artificial
Ventilation in Cardiac Surgery
The purpose of this study is to evaluate prospectively ventilatory practices in the perioperative cardiac surgery period.
- Conditions
- Respiratory Complication, Respiration, Artificial, Anesthesia, General, Bypass, Cardiopulmonary
- Trial name
- VENICE (NCT03255356)
- Testing
- Survey
- Where
- 10 sites in Belgium, Brazil and 8 more
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Caen
Tooth Extraction
Assessing Levels of Fear and Anxiety and Monitoring Wound Healing Among Patients Who Are About to Undergo Wisdom Tooth Extraction Surgery or Jaw Implant Surgery Under Local Anesthesia Versus General Anesthesia
Tooth extraction is one of the most common surgical procedures in dentistry. Up to 15% of the world's adult population suffers from high anxiety about dental treatments.
- Trial name
- NCT06473922
- Testing
- Reginal anesthesia
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Assaf-Harofeh Medical Center
Laparoscopic Cholecystectomy, Vector Electrocardiography
Electrocardiographic Changes in Cholecystectomy Surgery
Laparoscopic (closed) surgery provides several advantages over open surgery, such as smaller surgical incisions, postoperative recovery, and shorter hospital stay.
- Trial name
- NCT06651450
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Tokat Gaziosmanpasa University
Morning Operation, Evening Operation
Comparison of Morning Operation and Evening Operation on Postoperative Sleep Quality and Pain Under General Anesthesia
General anesthesia is a medically induced state of low reactivity consciousness involving amnesia, immobility, unconsciousness, and analgesia, which is similar to natural sleep.
- Conditions
- Morning Operation, Evening Operation, Sleep Quality, General Anesthesia
- Trial name
- NCT04094376
- Testing
- receiving operation during the day or at night
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shengjing Hospital
Surgery, Vascular Diseases
NMES for Rehab After Surgery
A randomised pilot study assessing the acceptability and feasibility of utilising neuromuscular stimulation devices to enhance post-operative rehabilitation and recovery after general, vascular and urological surgery procedures.
- Trial name
- NCT04784962
- Testing
- Revitive Medic Neuromuscular Stimulation Device
- Where
- United Kingdom
- Volunteers
- 103 people
- Sponsor
- Imperial College London
General Anaesthesia, Airway Devices
Sevoflurane Versus Propofol for Laryngeal Mask Airway Placement in Children Undergoing Surgery
The goal of this clinical trial is to compare two commonly used anesthetic medicines, sevoflurane and propofol, for inserting a laryngeal mask airway (LMA) in children undergoing minor elective surgery.
- Conditions
- General Anaesthesia, Airway Devices, Airway Control
- Trial name
- NCT07673003
- Testing
- propofol, Sevoflurane
- Where
- Pakistan
- Volunteers
- 170 people
- Sponsor
- Children's Hospital and Institute of Child Health, Multan
Surgery
Effect of Dexmedetomidine on QT Interval in Pediatric Patients Under General Anesthesia
Various medications used in anesthesia have been implicated in the prolongation of QT interval. Recently, there has been an increase in the use of dexmedetomidine in patients presenting for surgeries given its beneficial…
- Trial name
- NCT01917786
- Testing
- ECG
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Senthil G. Krishna
General Anesthesia Induction for Elective Surgery, Sono Guided Catheterization
Sonographic Safety Margins of Subclavian Vein: Effect of View and Arm Position
The purpose of this observational study is to evaluate and compare the anatomical safety margins of the subclavian vein using ultrasound.
- Trial name
- NCT07556770
- Testing
- Non-invasive sonographic observation
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Asan Medical Center
Anastomotic Leakage in Colon Surgery, Anastomotic Leak Rectum
Anastomotic Leakage in Colorectal Cancer Surgery in Syria
Anastomotic leakage is a serious complication of colorectal cancer surgery, particularly in resource-limited and conflict-affected settings.
- Conditions
- Anastomotic Leakage in Colon Surgery, Anastomotic Leak Rectum, Anastomotic Leak Large Intestine
- Trial name
- NCT07092631
- Where
- Syria
- Volunteers
- 119 people
- Sponsor
- Elie Bitar
Surgery--Complications, Atelectasis
The Incidence of Postoperative Pulmonary Complications in Patients With a Positive and Negative AIR-Test During General Anesthesia
The overall objective of this study is to describe the incidence of postoperative pulmonary complications in patients with a positive and negative AIR-test result.
- Conditions
- Surgery--Complications, Atelectasis, Anesthesia
- Trial name
- NCT05345743
- Testing
- Surgery
- Where
- Netherlands
- Volunteers
- 632 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
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