Clinical trials: Global Surgery
Intubation; Difficult or Failed, Videolaryngoscopy
Videolaryngoscopic Intubation Using Macintosh vs.Hyperangulated Blades in Patients With Expected Difficult Intubation
Videolaryngoscopy-guided intubation has become widespread as a means of preventing major complications relating to airway management by improving the glottic view, increasing the first attempt success rate, likely reduce rates of…
- Conditions
- Intubation; Difficult or Failed, Videolaryngoscopy, General Anesthesia
- Trial name
- NCT05522049
- Testing
- hyperangulated videolaryngoscope, Macintosh videolaryngoscope
- Where
- Germany
- Volunteers
- 182 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Laparoscopic Surgery, Laparoscopic Entry Technique
Laparoscopic Access in General Surgery: the Closed (Veress Needle) Technique Versus the Open (Hasson) Technique
A randomised controlled trial (RCT) comparing the closed (Veress needle) with the open (Hasson) laparoscopic entry technique in haemodynamically stable patients undergoing either emergency or elective surgical procedures was…
- Trial name
- NCT03506555
- Testing
- Laparoscopic peritoneal entry technique: Veress needle versus Hasson
- Volunteers
- 96 people
- Sponsor
- Sefako Makgatho Health Sciences University
Colon Cancer
Follow-up After Surgery for Colon Cancer. General Practice vs. Surgical-based Follow-up?
The purpose of this study is to clarify cost effectiveness and quality of life issues among colon cancer patients followed up in a hospital setting or by their GP's.Statement of study hypothesis:Postoperative follow up of colon…
- Trial name
- ONKOLINK (NCT00572143)
- Testing
- ca coli follow-up by GP
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- University Hospital of North Norway
Rotator Cuff Tear, Shoulder Surgery
Interscalene Brachial Plexus Block and Early Wound-Related Symptoms After Open Rotator Cuff Repair
This exploratory randomized controlled trial evaluated the association of interscalene brachial plexus block (ISB) with early postoperative wound-related symptom scores and perioperative biomarker responses in patients undergoing…
- Conditions
- Rotator Cuff Tear, Shoulder Surgery, Postoperative Recovery
- Trial name
- NCT05499897
- Testing
- Ultrasound-Guided Interscalene Brachial Plexus Block, General Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Yuzuncu Yil University
Breast Carcinoma, Breast Carcinoma in Situ
Postoperative Pain After Breast Surgery Under Tumescent Local Anaesthesia Versus General Anaesthesia ( TLA-001 )
The present study aims to investigate the impact of Tumescent Local Anesthesia (TLA) on pain perception following surgeries typical for breast cancer.
- Trial name
- NCT06335108
- Testing
- General Anaesthesia, Local tumescent anaesthesia
- Where
- Germany
- Volunteers
- 349 people
- Sponsor
- University Hospital Tuebingen
Gastrointestinal Dysfunction
Clinical Study on the Treatment of Gastrointestinal Dysfunction After Knee Joint Surgery Under General Anesthesia With Floating Needle
A randomized controlled trial was conducted to compare the clinical efficacy of Fu's subcutaneous acupuncture and western medication in the treatment of gastrointestinal dysfunction after knee surgery under general anesthesia.
- Trial name
- NCT07607249
- Testing
- Fu's Acupuncture group, Mosapride
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Zhenyu Zhang
Pediatric Surgical Procedures, Adult Surgical Procedures
A Study of HARMONIC 700 Shears With Advanced Hemostasis in Pediatric and Adult Surgical Procedures
The main purpose of this study is to demonstrate acceptable performance and assess safety of the HARMONIC 700 Shears device in a post-market setting when used per the instructions for use in pediatric and adult surgical…
- Conditions
- Pediatric Surgical Procedures, Adult Surgical Procedures, Adult Gynecological Procedures, Adult Urological Procedures
- Trial name
- NCT06608485
- Testing
- HARMONIC 700 Shears
- Where
- 7 sites in United States, Canada and 1 more
- Volunteers
- 173 people
- Sponsor
- Ethicon Endo-Surgery
Postoperative Pain, Ambulatory Surgery
Comparison Between Pre-operative Prescription Delivered During Anesthesia Consultation or Post-operative Prescription
This study evaluates the comparison of the incidence of postoperative home pain after ambulatory surgery with general anesthesia between a group with pre-surgical prescription delivered during anesthesia preoperative clinic and a…
- Conditions
- Postoperative Pain, Ambulatory Surgery, Anesthesia, Postoperative Complication
- Trial name
- AMBUPRESS (NCT03205189)
- Testing
- Comparison between pre-operative prescription and post-operative prescription
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Ankle Sprains, Instability, Joint
The Clinical Outcomes of the Modified Broström vs Anatomic Reconstruction Operation in CLAI and GJL
Investigators designed this prospective cohort study to compare the clinical outcomes of modified Broström operation and anatomical reconstruction for the treatment of CLAI and GJL.
- Conditions
- Ankle Sprains, Instability, Joint, Joint Hypermobility
- Trial name
- NCT05196906
- Testing
- Modified Broström operation and anatomic reconstruction operation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Older Patients, Nasal Administration
Dexmedetomidine-esketamine Combined Nasal Administration and Emergence Delirium
Emergence delirium is common in older patients after surgery and associated with worse perioperative outcomes, including increased postoperative delirium.
- Conditions
- Older Patients, Nasal Administration, Dexmedetomidine, Esketamine
- Trial name
- NCT06566469
- Testing
- Dexmedetomidine, Esketamine, Normal saline
- Where
- China
- Volunteers
- 340 people
- Sponsor
- Peking University First Hospital
Craniosynostosis, Anesthesia
Influence of General Anesthesia on the Dynamic Changes in Brain Damage Markers During and After Craniosynostosis Operations in Infancy
The issue of anesthetics neurotoxicity is one of the most discussed topics in pediatric anesthesiology, thus it opens the question of the safety of commonly used anesthetics in the pediatric patient.
- Trial name
- TAnBrainDam (NCT05911139)
- Where
- Slovakia
- Volunteers
- 45 people
- Sponsor
- Comenius University
Perioperative Hypothermia
Incidence of Perioperative Hypothermia in Patients With Elective Surgery Under General Anesthesia in Turkey
Primary objective of the study is to project the incidence rate of perioperative hypothermia under general anesthesia in patients who go under minimum 1 hour long elective surgery in at least 25 hospitals/medical centers in…
- Trial name
- GAPOHI (NCT02736630)
- Testing
- body temperature
- Volunteers
- 3,000 people
- Sponsor
- Turkish Society of Anesthesiology and Reanimation
Pain, Postoperative
Comparing Analgesic Efficacy of Systemic Lidocaine Against Placebo in General Anesthesia in Bariatric Surgery
The investigators plan to evaluate the analgesic effect of systemic Lidocaine in addition to general anesthesia during bariatric surgery. Patients will be subdivided into a "Lidocaine group" and a "Control group".
- Trial name
- COALAS (NCT03667001)
- Testing
- Lidocaine Hydrochloride, Saline Solution
- Where
- Switzerland
- Volunteers
- 140 people
- Sponsor
- Miodrag Filipovic, Prof. Dr. med.
Gynecological Surgery
Effect of Combined Administration of Sevoflurane and Remimazolam on Emergence
Enhanced recovery after surgery (ERAS) protocols are being explored to improve patient outcomes. The method of inducing anesthesia and maintenance using inhalation anesthetics is common but may delay recovery.
- Trial name
- NCT06385002
- Testing
- Remimazolam
- Where
- South Korea
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Anesthesia Morbidity, Anesthesia; Adverse Effect
Comparison of CLSB With Sedation Versus General Endotracheal Anesthesia on Postoperative Outcomes in Elderly Patients Undergoing Hip Fracture Surgery
Hip fracture is a global public health problem. The postoperative mortality and disability rate of hip fracture is high, and early surgery is still the most effective treatment method, but these patients are often associated with…
- Trial name
- NCT03318133
- Testing
- anesthesia
- Where
- China
- Volunteers
- 1,086 people
- Sponsor
- Shanghai 6th People's Hospital
Perfusion Index, Hypothermia; Anesthesia
The Impact of Intraoperative Change in the Body Temperature on the Perfusion Index
The goal of this observational study is to learn about the impact of intraoperative change in temperature in adult patients undergoing surgeries under general anaesthesia.
- Trial name
- NCT06998849
- Testing
- Perfusion index
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Elective Surgery, High Risk
General Decolonization With Octenisan® Set Before Elective Orthopedic Surgery
The general decolonization of the human body surface by industrial antiseptic agents, before elective surgery is recommended by the World Health Organization (WHO).
- Conditions
- Elective Surgery, High Risk, Prevention of Surgical Site Infections, Randomized-controlled Trial
- Trial name
- BALGDEC (NCT05647252)
- Testing
- Whole Body and nasal decolonization with octenidin (Octenisan Set), Questionnaire for study participants immediately after the decolonization
- Where
- 2 sites in Switzerland
- Volunteers
- 1,086 people
- Sponsor
- Balgrist University Hospital
Education, Training
Trial of Proficiency- Based Simulation Training for General Surgical Trainees
The hypothesis of this trial is to demonstrate that training junior surgeons on a virtual reality (VR) simulator in addition to didactic teaching will improve their intraoperative performance compared to those trainees who…
- Conditions
- Education, Training, Computer Simulation
- Trial name
- NCT00712387
- Testing
- LapSim simulator
- Where
- 14 sites in Ireland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Pregnancy, Cesarean Delivery
Pharmacogenetics of Remifentanil in Patients With Hypertension Undergoing Cesarean Delivery Under General Anesthesia
Caesarean delivery under general anaesthesia (GA) carries nowadays still 25% risk of insufficient depth of anaesthesia in a time before the fetus delivery. The reason is the lack of opioid administration.
- Conditions
- Pregnancy, Cesarean Delivery, General Anesthesia
- Trial name
- NCT01550640
- Testing
- Remifentanil
- Where
- Czechia
- Volunteers
- 149 people
- Sponsor
- Charles University, Czech Republic
Airway Ultrasound
Airway Ultrasound As an Independent Predictor of Difficult Laryngoscopy in Patients Receiving General Anesthesia for Elective Surgery
The goal of this observational study is to determine the usefulness of pre-operative airway ultrasound in predicting difficult laryngoscopy in patients receiving general anesthesia for elective surgery.
- Trial name
- NCT06391840
- Testing
- Airway ultrasound
- Where
- Greece
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- DIMITRIOS KATSAROS
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