Clinical trials: Global Surgery
Bronchospasm, Surgery
Observational Study on Obese Patients During General Anesthesia
There is increased frequency of asthma in obese patients. This study is trying to find out if there is a difference in the presence of bronchospasm during anesthesia in obese and non obese patients.
- Conditions
- Bronchospasm, Surgery, Obesity
- Trial name
- NCT01488643
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Larissa University Hospital
Wisdom Teeth Extraction or Jaw Implant
Levels of Fear, Anxiety and Wound Healing Among Aental Surgery Patients Under Local Versus General Anesthesia
Tooth extraction is one of the most common procedures in dentistry. Surgical extraction of damaged wisdom teeth involves bone resection and injury to the soft tissue.
- Trial name
- NCT06380608
- Testing
- Local anesthesia, General anesthesia
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Zoya Haitov Ben Zikri
Knee Arthroscopy
Chloroprocaine Spinal for Outpatient Knee Surgery
Outpatient knee surgeries with duration of less than one hour pose a challenge to the use of spinal anesthesia given that traditional agents remain in effect for 2-3 hours, thus creating a mismatch between length of surgery and…
- Trial name
- NCT03365752
- Testing
- Chloroprocaine, Mepivacaine, General Anesthetics
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Hospital for Special Surgery, New York
IOP Changes Due to Anesthesia (Healthy Patients)
The Effect of Different Sevoflurane Concentrations on Intraocular Pressure in Patients Undergoing Ocular Surgery Under General Anesthesia
One important goal in anesthetic management during ocular surgery is to provide adequate control of intraocular pressure (IOP). An increase in IOP may be catastrophic in patients with glaucoma or a penetrating open-eye injury.
- Trial name
- NCT01575626
- Testing
- Sevoflurane
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
ASA Class I/II Patients Scheduled for Surgery Under General Anesthesia
Nitrous Oxide - Sevoflurane-Remifentanil Interaction
patients are allocated to one of the two study groups. In both groups a mixture of 60% nitrous oxide and 40% oxygen is administered through a face mask.
- Trial name
- NCT01103193
- Testing
- remifentanil injected, sevoflurane in step up concentration
- Where
- Belgium
- Volunteers
- 4 people
- Sponsor
- University Hospital, Ghent
Pain, Postoperative
Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia
The purpose of this study is to investigate the effectiveness of various oral analgesic regimens in minimizing post-operative pain and discomfort in young children following dental rehabilitation under general anesthesia (DRGA).
- Trial name
- NCT06757075
- Testing
- Ibuprofen, Acetominophen
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Boston University
Generalized Aggressive Periodontitis
Effects Of Adjunctive Photodynamic Therapy To Non-Surgical Periodontal Treatment In Patients With Generalized Aggressive Periodontitis
Generalized aggressive periodontitis (GAgP) is a distinct type of periodontal disease characterized by rapid loss of attachment and alveolar bone occuring in young individuals.
- Trial name
- NCT03412331
- Testing
- Ultrasonic, Hand Instruments, LED Source
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dreaming, General Anesthesia
Dreaming During Anesthesia and Anesthetic Depth in Elective Surgery Patients Under General Anesthesia
Dreaming is a common, enduring, and fascinating part of the anesthetic experience, but its cause and timing remain elusive. Patients typically report that they were dreaming during anesthesia, but the actual timing of anesthetic…
- Trial name
- NCT05357872
- Testing
- deep anesthesia depth, light anesthesia depth
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Surgical Site Infection, Superficial Surgical Site Infection
Clipping Versus No Hair Removal and the Risk of Surgical Site Infections
The objective of this study is to determine whether hair clipping is non-inferior to no hair removal in preventing superficial, deep, and organ space surgical site infections (SSI) in patients undergoing various general surgical…
- Conditions
- Surgical Site Infection, Superficial Surgical Site Infection, Deep Surgical Site Infection, Organ/Space Surgical Site Infection
- Trial name
- NCT00975377
- Testing
- Hair clipping
- Where
- United States
- Volunteers
- 1,678 people
- Sponsor
- Gundersen Lutheran Medical Foundation
Open Surgery, Lymphedema
A Global, Prospective, Real-World, Investigation of the Symani® Surgical System for Microsurgical Anastomosis
The objective of this clinical study is to evaluate the Symani System's safety and effectiveness for microsurgical anastomosis during free tissue transfer surgery and lymphatic surgery.
- Conditions
- Open Surgery, Lymphedema, Free Tissue Transfer, Microsurgery
- Trial name
- PRIME (NCT06628219)
- Testing
- Symani Surgical System
- Sponsor
- MMI (Medical Microinstruments, Inc.)
Trauma Injury, Maxilla Fracture
Prospective Study to Evaluate the Performance and the Safety of Global D's Implants of Craniomaxillofacial Surgery (CMF) Ranges Indicated for Trauma Surgery
This study is set up within the framework of the European Union regulation 2017/745 on medical devices. Its objective is to confirm the performance and safety of the Global D implants (ORTRAUTEK® and MINITEK/MICROTEK®) used for…
- Conditions
- Trauma Injury, Maxilla Fracture, Maxillofacial Trauma
- Trial name
- NCT05742932
- Testing
- Trauma surgery using Global D's implants.
- Where
- 2 sites in France
- Volunteers
- 99 people
- Sponsor
- Global D
Elective Surgery of Short Duration (Less Than 2 hr) Undergoing General Anesthesia Using Supraglottic Airway
The Comparison of the Clinical Efficacy Between I-gel and LMA-Supreme, the Two Most Recently Developed Supraglottic Airway Devices, in Infants
Although the safety and efficacy of the I gel in children has been shown in several large observational studies, There is no study about comparison of the clinical efficacy between I-gel and LMA-Supreme , in particular sizes 1…
- Trial name
- NCT01863316
- Testing
- I gel, LMA Supreme
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Laparoscopic Cholecystectomy, Postoperative Sore Throat
Low-Flow Sevoflurane and Desflurane Anesthesia in Laparoscopic Cholecystectomy
Several studies have demonstrated that inhalational anesthetic agents such as desflurane and sevoflurane may cause varying degrees of postoperative sore throat, hoarseness, and cough in orotracheally intubated patients.
- Trial name
- NCT07440758
- Testing
- Sevoflurane, Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kayseri City Hospital
Vitreoretinal Surgeries, Postoperative Nausea and Vomiting
Paracetamol and Metamizole With SPI-guided Anaesthesia for VRS
The aim of this randomized trial is to assess the efficacy of preemptive analgesia using paracetamol or metamizole or both of them under SPI-guided anaesthesia for vitreoretinal surgery (VRS), presence of PONV (postoperative…
- Conditions
- Vitreoretinal Surgeries, Postoperative Nausea and Vomiting, Postoperative Pain
- Trial name
- P&MSPIVRS (NCT03389243)
- Testing
- Metamizol, paracetamol, paracetamol and metamizole
- Where
- Poland
- Volunteers
- 165 people
- Sponsor
- Medical University of Silesia
Intervention Affecting Autonomic Nervous System
Exploration of Autonomic Nervous System by Photoplethysmography
The autonomic nervous system state (ANSS) and the autonomic nervous system state index (ANSSi) - two indices derived from the pulse photo-plethysmography analysis - have been recently advocated as a measure of sympathetic…
- Trial name
- NCT02324478
- Testing
- autonomic nervous system analysis
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- ASST Fatebenefratelli Sacco
General Anaesthesia
Comparative Clinical Study of Efficacy and Safety of Remimazolam and Propofol in Patients Undergoing Elective Surgery Under General Anaesthesia
The purpose of this study was to perform comparative evaluation of clinical efficacy and safety of Remimazolam and Propofol for induction and maintenance of general anesthesia in patients undergoing elective surgery under general…
- Trial name
- NCT03669484
- Testing
- Remimazolam, Propofol, Fentanyl
- Where
- 6 sites in Russia
- Volunteers
- 150 people
- Sponsor
- R-Pharm
Stress, Pain
Evaluation of the Surgical Pleth Index During Spinal and General Anesthesia
The Surgical Pleth index (SPI) has been introduced as a non invasive tool to "measure" stress and pain during surgery. Preliminary studies were performed in patients under general anaesthesia with propofol and remifentanil.
- Trial name
- NCT00789438
- Where
- Germany
- Volunteers
- 69 people
- Sponsor
- University Hospital Schleswig-Holstein
Verapamil, Diltiazim
Efficacy of Oral Verapamil and Oral Diltiazim on Reduction of Intraoperative Bleeding During Endoscopic Sinus Surgery Under General Anesthesia
To study the effect of addition of oral verapamil or Diltiazim to general anaesthesia on the Intraoperative haemodynamics : heart rate(HR), noninvasive blood pressure(NIBP), mean arterial blood pressure(MAP), and the blood loss…
- Conditions
- Verapamil, Diltiazim, FESS
- Trial name
- NCT04790331
- Testing
- Verapamil, Diltiazem
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Assiut University
Patients Undergoing General Anesthesia
Deep Neuromuscular Block With Pipecuronium in Patients Undergoing Robotic Thoracic Surgery
Robotic-assisted surgery is rapidly expanding across surgical specialties, including thoracic surgery. Compared with conventional techniques, robotic surgery provides the surgeon with a three-dimensional view and highly precise…
- Trial name
- Deep block (NCT07868094)
- Testing
- Electromiograph
- Where
- Hungary
- Volunteers
- 19 people
- Sponsor
- University of Debrecen
Major Abdominal Surgery
Paravertebral Block vs. General Anesthesia for Major Abdominal Surgery
Elderly patients are usually presented with higher risk for developing cardiopulmonary complications after general anesthesia (GA).
- Trial name
- NCT02534012
- Testing
- Paravertebral block, General anesthesia, Major abdominal surgery
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Makassed General Hospital
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