Clinical trials: Global Surgery
Otosclerosis
The Cost-effectiveness of Stapes Surgery for Otosclerosis Performed Under Local Versus General Anesthesia
Otosclerosis is a localized disorder of the otic capsule, characterized by bone resorption anterior to the oval window in the region of the fissula ante fenestram.
- Trial name
- CESSO (NCT06618053)
- Testing
- cost-effectiveness and audiometry outcomes
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
General Surgery, Cholecystectomy
Surgical Practices in Algeria : the Cholecystectomy
An anonymous national survey involving all practicing Algerian surgeons was conducted. At the end of the survey, all data were captured and processed using the SPSS v20 software; χ 2 tests were used to compare different groups of…
- Conditions
- General Surgery, Cholecystectomy, Practice Guidelines as Topic
- Trial name
- NCT04270357
- Testing
- Cholecystectomy
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Oran 1
General Surgery, Perioperative Medicine
Preoperative Walking Evaluation and Postoperative Outcome
The hypothesis is that physical activity is associated with a reduced risk of complications and death after surgery. Self-reporting of physical activity is prone to be unreliable.
- Trial name
- PREVENT (NCT06023069)
- Testing
- Number of steps recorded by mobile phone as a proxy for physical activity
- Where
- Sweden
- Volunteers
- 264 people
- Sponsor
- Karolinska Institutet
Obesity &Amp; Overweight, General Anesthetic
Postoperative Opioid Consumption in Gastric Sleeve Surgery
The study aimed to compare balanced anesthesia protocols using only opioids as analgesics during induction in gastric sleeve surgery with protocols using opioids and ketamine together in terms of anesthesia management, opioid…
- Conditions
- Obesity &Amp; Overweight, General Anesthetic, Ketamine
- Trial name
- POCiGSS (NCT07135154)
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Balikesir University
Morbid Obesity
Dietary Intake After Laparoscopic Sleeve Gastrectomy -a 5 Year Study
Weight reducing surgery is the only effective therapy for morbid obese patients. Sleeve gastrectomy is a popular choice for bariatric surgery because of less sequela.
- Trial name
- NCT02193529
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Min-Sheng General Hospital
Chronic Periodontitis, Generalized
The Effects of Periodontal Therapy on Glycemic Control in Diabetic Patients
Is the non-surgical periodontal therapy can improve glycemic control in type 2 diabetic patients with chronic periodontitis?
- Trial name
- NCT03783845
- Testing
- amoxicillin 500mg and metronidazole 400mg
- Volunteers
- 44 people
- Sponsor
- Taibah University
Music Therapy, General Anesthesia
Intraoperative Music Therapy in Gynecological Oncology
Background Perioperative anxiety and postoperative pain can impact surgical morbidity. We aimed to evaluate the effect of intraoperative music therapy in the reduction of immediate postoperative pain in patients undergoing…
- Conditions
- Music Therapy, General Anesthesia, Surgery, Pain
- Trial name
- NCT04694508
- Testing
- Headphones (Disok, Alicante, España)
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Neuromuscular Blockade, Residual Curarisation, Postoperative
Provider Variability in the Use of Neuromuscular Blocking Drugs and Reversal
The use of neuromuscular blocking agents during surgery is associated with postoperative respiratory complications and increased risk of readmission to the hospital following ambulatory surgery.
- Conditions
- Neuromuscular Blockade, Residual Curarisation, Postoperative, Surgery Under General Anaesthesia
- Trial name
- NCT03585348
- Testing
- Neuromuscular blocking agents
- Where
- 2 sites in United States
- Volunteers
- 265,537 people
- Sponsor
- Beth Israel Deaconess Medical Center
Postoperative Pain, Arm Injury
Plasma Concentration of Somatostatin and Endocannabinoids After GA and RA in Upper Extremity Trauma Surgery
The application of RA can decrease the central sensitization and chronic pain after trauma surgery. The plasma concentrations of somatostatin and fatty acid amides were not studied up to this time in this kind of settings, so…
- Trial name
- SECsGRUES (NCT04040738)
- Testing
- Upper extremity surgery under general anaesthesia, Upper extremity surgery under regional anaesthesia
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- University of Pecs
Reversing Vecuronium-Induced Neuromuscular Blockade in Patients Undergoing General Anesthesia Surgery, Reversing Rocuronium-Induced Neuromuscular Blockade in Patients Undergoing General Anesthesia Surgery
A Dose-Finding Study of Amogammadex Sodium for Reversing Vecuronium and Rocuronium-Induced Neuromuscular Blockade
Background context: Amogammadex sodium has completed Phase I-III clinical studies in China for reversal of rocuronium-induced blockade. No clinical studies have yet been conducted for vecuronium-induced blockade.
- Trial name
- NCT07595393
- Testing
- Rocuronium (0.6mg/kg), vecuronium bromide (0.1mg/kg)
- Volunteers
- 64 people
- Sponsor
- Amckaus PTY LTD.
Pharyngitis
Combined Effect of Dexamethasone and Paracetamol for Postoperative Sore Throat
The investigators want to evaluate the efficacy of the dexamethasone and paracetamol for the prevention of postoperative sore throat.
- Trial name
- NCT02252419
- Testing
- Dexamethasone, Paracetamol
- Where
- South Korea
- Volunteers
- 242 people
- Sponsor
- Seoul National University Hospital
Thyroid Cancer
Effect of Perioperative Intravenous Lidocaine Infusion and Magnesium Infusion on the Functional Recovery After General Anesthesia in the Patients Undergoing Thyroid Surgery
Studies have attempted to control pain and increase patients' recovery satisfaction following many kinds of operations by using as small an opioid analgesic dose as possible and adding a nonopioid analgesic to reduce the side…
- Trial name
- NCT02018276
- Testing
- Lidocaine, Magnesium
- Where
- South Korea
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Cardiac Surgical Procedures, Retained Blood Syndrome
CPPF After General Cardiac Surgery
In two randomized clinical trials the investigators have demonstrated that continuous postoperative pericardial flushing (CPPF) therapy can reduce postoperative blood loss and bleeding-related complications after cardiac surgery…
- Conditions
- Cardiac Surgical Procedures, Retained Blood Syndrome, Cardiac Tamponade, Postoperative Hemorrhage
- Trial name
- FLUID (NCT05308589)
- Testing
- CPPF
- Where
- 4 sites in Netherlands
- Volunteers
- 164 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Idiopathic Normal Pressure Hydrocephalus
Gait Pattern and Experienced Global Change After Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus
Part 1 Patients with idiopathic Normal Pressure Hydrocephalus (iNPH) have variable disabilities regarding gait, balance, cognition and continence.
- Trial name
- NCT04795089
- Testing
- Shunt surgery
- Where
- Sweden
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Behavior Problem
Intranasal Dexmedetomidine or Esketamine for Negative Postoperative Behavioral Changes in Children
The goal of this clinical trial is to learn whether intranasal dexmedetomidine or esketamine given before anesthesia can reduce negative postoperative behavioral changes in children undergoing day surgery.
- Trial name
- PEDI-NPOBCs (NCT07570160)
- Testing
- Dexmedetomidine, Esketamine, Normal Saline
- Where
- China
- Volunteers
- 342 people
- Sponsor
- Nanjing Children's Hospital
Pelvic Floor Disorders
Factors Influencing Hemodynamic Stability and Its Management in Patients Undergoing Pelvic Surgery Under Spinal and GA
Patients are at risk for hemodynamic instability both during and after surgery, as it is an independent predictor of long-term patient morbidity and length of hospital stay.
- Trial name
- NCT06767397
- Testing
- general anesthesia
- Where
- Pakistan
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Superior University
Vitiligo, Generalized
Autologous Cellular Graft in Surgical Treatment of Vitiligo
This is a double blinded self controlled randomized trial to assess Autologous Micro Cellular Grafts in surgical treatment of stable resistant vitiligo.
- Trial name
- NCT05503368
- Testing
- surgical treatment of vitiligo using NCES
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Healthy
I-Gel Versus Disposable Laryngeal Mask (LMA) for General Anesthesia (GA) With Controlled Ventilation
Randomized controlled trial comparing performance of the I-gel and disposable Laryngeal Mask Airways under controlled ventilation. 200 patients, 100 in each arm. Measurement of peak airway and sealing pressures.
- Trial name
- IGE(L)MA (NCT00668278)
- Testing
- Insertion of laryngeal mask airway (AuraOnce mask), Insertion of I-gel airway, Measurement of airway pressures
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Northern Health and Social Care Trust
Pain
Combined Anesthesia for Laparoscopy Surgery in Gynecology
The purpose of this study is to determine whether combined anesthesia will provide better pain control for the postoperative period following gynecological laparoscopy surgery.
- Trial name
- NCT01246323
- Testing
- Spinal anesthesia with Fentanyl+ Morphine
- Where
- 2 sites in Israel
- Volunteers
- 40 people
- Sponsor
- Rambam Health Care Campus
Neurodevelopmental Disorders, Child Behavior
Neurodevelopmental Outcome After Prenatal Anesthesia
In 2016, the US Food and Drug Administration raised concerns about the potential negative effects of anesthesia exposure on neurodevelopment in children during pregnancy or before the age of three.
- Trial name
- NCT06052878
- Testing
- Parental telephone interview with standardized parental questionnaire from the "Behaviour Rating Inventory of Executive Function" (BRIEF), Parental questionnaire about their child's cognitive functioning in their daily life and medical history.
- Where
- France
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
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