Clinical trials: Global Surgery
Postoperative Delirium, Postoperative Recovery in Elderly Patients
Recovery After Upper Extrimety Surgery
The goal of this randomized clinical trial is to determine whether Bispectral Index (BIS)-guided general anesthesia improves postoperative cognitive recovery and overall quality of recovery in adults undergoing elective hand or…
- Conditions
- Postoperative Delirium, Postoperative Recovery in Elderly Patients, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- Recovery (NCT07714928)
- Testing
- BIS-Guided General Anesthesia, Clinically Guided General Anesthesia
- Where
- Sweden
- Volunteers
- 112 people
- Sponsor
- Region Örebro County
Hypothermia Following Anesthesia, Hypothermia, Accidental
Comparison of Active Prewarming Versus Standard Care to Prevent Perioperative Hyporthermia in Short Outpatient Surgery Under General Anesthesia
The purpose of this prospective randomized controlled study is to compare the efficiency in preventing perioperative hypothermia of a continuous active prewarming combined with active intraoperative warming versus passive…
- Trial name
- PREWARMING (NCT04601636)
- Testing
- Active Prewarming, Standard Care
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Anesthesia
Psychological Assessment Before General Anesthesia (VeSPPA2018)
The level of preoperative anxiety can be related to the outcome of an operation and to the post operative patient management . The Dutch questionnaire APAIS (Amsterdam Preoperative Anxiety and Information Scale) is a useful tool…
- Trial name
- NCT03818464
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Parma
Endothelial Dysfunction, Ischemia Reperfusion
Effects of Anesthesia Technique on Endothelial Function
The aim of this study was to compare the effects of two different anesthesia methods, general anesthesia and infraclavicular block, on oxidative stress and endothelial dysfunction in upper extremity forearm operations.This…
- Conditions
- Endothelial Dysfunction, Ischemia Reperfusion, Oxidative Stress
- Trial name
- NCT06515028
- Testing
- Group GA, Group IB
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Bagcilar Training and Research Hospital
Breast Cancer
Comparing Local Anesthesia With General Anesthesia for Breast Cancer Surgery
The purpose of this study is to determine therapeutic benefits by local anesthetic technique for breast cancer.
- Trial name
- NCT00938171
- Testing
- Local anesthesia, General anesthesia
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Mackay Memorial Hospital
General Anesthesia; Pediatric Surgery; Intraoperative Music Therapy; Operating Room Noise Reduction; Anesthetic Requirement; Analgesic Requirement
Effect of Intraoperative Instrumental Music and Operating Room Noise Reduction on Anesthetic and Analgesic Requirements in Pediatric Patients Aged 3-18 Years Undergoing Surgery Under General Anesthesia: A Randomized Controlled Trial
This randomized controlled clinical trial aims to evaluate the effects of intraoperative instrumental music and operating room noise reduction on anesthetic and analgesic requirements in pediatric patients aged 3-18 years…
- Trial name
- MUSIC-OR (NCT07630675)
- Volunteers
- 180 people
- Sponsor
- Ankara City Hospital Bilkent
Periodontitis
Non-Surgical Treatment of Periodontitis With Adjunctive Sodium Hypochlorite/Amino Acids and Cross-Linked Hyaluronic Acid
The goal of this clinical trial is to learn if using sodium hypochlorite/amino acid gel, with or without cross-linked hyaluronic acid, as an addition to standard non-surgical periodontal therapy works to treat periodontitis in…
- Trial name
- NCT07474272
- Testing
- Standard Non-Surgical Periodontal Therapy, tandard Therapy + Sodium Hypochlorite/Amino Acid Gel, Standard Therapy + Sodium Hypochlorite/Amino Acid Gel + Cross-Linked Hyaluronic Acid
- Where
- Lebanon
- Volunteers
- 78 people
- Sponsor
- Marwan El Mobadder
The Study Was Aimed to Assessing the Clinical Profile of Acute Abdomen and Their Frequency According to Age and Sex
A Retrospective Case Series Study for Acute Abdomen in General Surgery Ward
The acute abdomen is a clinical situation in which an acute an change in the condition of intra-abdominal organ, commonly attached to inflammation or infection need urgent and correct diagnosis .
- Trial name
- NCT05088200
- Testing
- surgery
- Where
- Afghanistan
- Volunteers
- 118 people
- Sponsor
- Ahmadullah Danish
Surgery With General Anesthesia, Gynecologic Surgical Procedures
COMPARISON OF PLAIN BLOCKS FOR POSTOPERATIVE PAIN MANAGEMENT IN GYNECOLOGICAL ABDOMINAL SURGERIES
This study compares the effects of transversus abdominis plane (TAP) block, quadratus lumborum block (QLB), and erector spinae plane block (ESP) on postoperative morphine consumption, pain scores, patient satisfaction, and side…
- Conditions
- Surgery With General Anesthesia, Gynecologic Surgical Procedures, Plane Block, Postoperative Pain Management
- Trial name
- ESP QLB TAP (NCT07021105)
- Testing
- ESP Plane block, QLB plane block, TAP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cukurova University
Opioid Misuse and Addiction, Pain
Toward Zero Prescribed Opioids for Outpatient General Surgery
Investigators have created an opioid reduction "package" which includes patient education, non-narcotic pain control instructions, and limited (or no) opioid pain prescriptions provided at discharge in an attempt to reduce the…
- Trial name
- NCT05327777
- Testing
- Oxycodone, Zero Opioid Protocol
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Gynecologic Surgical Procedures, Urologic Surgical Procedures
Study of Atelectasis by Electrical Impedance Tomography
The goal of this interventional study is to learn about the effects of different positions on the occurrence, regional distribution and reversibility of atelectasis by using a PulmoVista 500 monitor (Dräger.
- Trial name
- NCT05713929
- Testing
- Recruitment maneuver (RM), Reverse Trend (REV TREND)
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Erasme University Hospital
Carcinoma, Hepatocellular
Clinical Study of Effectiveness of Radiotherapy Before Surgery in High-risk Relapse Hepatocellular Cancer Patients
This study aims to evaluate the effectiveness of radiotherapy before surgery in high-risk relapse hepatocellular cancer patients.
- Trial name
- NCT02580929
- Testing
- radiotherapy
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College
Delirium, Postoperative, Anesthesia
Depth of Anesthesia on Postoperative Delirium and Cognitive After Surgery
The goal of this clinical trial (Balanced-2 study) is to compare light to deep general anesthesia using widely available brain monitors, to see if 'light' anesthesia could reduce rates of delirium, cognitive decline, and…
- Conditions
- Delirium, Postoperative, Anesthesia, Surgery-Complications, Cognition Disorder
- Trial name
- Balanced-2 (NCT06268080)
- Testing
- Depth of anesthesia titration using pEEG
- Where
- 3 sites in New Zealand
- Volunteers
- 2,766 people
- Sponsor
- Auckland City Hospital
Surgery With General Anesthesia, Depression - Major Depressive Disorder
Perioperative Depression, an Observational Cohort Study
This observational cohort study studies two aspects of perioperative depression. First, it examines the postoperative morbidity and mortality among patients with preoperative depression.
- Trial name
- NCT06783842
- Where
- Sweden
- Volunteers
- 700,000 people
- Sponsor
- Karolinska Institutet
Post Operative Nausea and Vomiting
Association of 5-HT3 Receptor Gene Polymorphism With the Efficiency of Ondansetron for Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) is a common and distressing complication in patients undergoing general anesthesia. However, although 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists have significantly reduced…
- Trial name
- NCT01657786
- Testing
- administration of ondanstron and screening of genomic DNA
- Where
- South Korea
- Volunteers
- 198 people
- Sponsor
- Yonsei University
Hyperparathyroidism
Interaction Between Anaesthetics and Methylene Blue
We hypothesized that pre-treatment with methylene blue could potentiate the effects of general anaesthetic agents in patients undergoing parathyroidectomy
- Trial name
- NCT00513032
- Testing
- methylene blue
- Where
- Switzerland
- Volunteers
- 22 people
- Sponsor
- University Hospital, Geneva
Emergence Agitation, Pain
Can Acetaminophen Given 1-2 Hours to Children Before Ear Tube Surgery Reduce Agitation After Anesthesia?
Emergence agitation (EA) occurs in up to 67% of pediatric patients after anesthesia for bilateral myringotomy tubes (BMT, "ear tubes").
- Trial name
- NCT01737593
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Anesthesia Induced Hypothermia, Inadvertent Perioperative Hypothermia
Study to Evaluate Safety and Efficacy of Blanket Used to Prevent Anesthesia Induced Hypothermia
The investigation was designed as an Open-Label, Multicenter, Randomised, Controlled Investigation to Evaluate the Efficacy and Safety of the BARRIER® EasyWarm Active Self-Warming Blanket Used for Continuous Active Warming to…
- Trial name
- NCT01900067
- Testing
- BARRIER® EasyWarm Active Self-Warming Blanket
- Volunteers
- 271 people
- Sponsor
- Molnlycke Health Care AB
Tracheal Intubation, Videolaryngoscopy
Video Versus Direct Laryngoscopy for Tracheal Intubation in Pediatric Surgery
Tracheal intubation in paediatric patients is a high-risk procedure in which failure to achieve successful intubation on the first attempt is associated with an increased risk of complications, including hypoxaemia and airway…
- Conditions
- Tracheal Intubation, Videolaryngoscopy, General Anesthesia, Difficult Airway Intubation
- Trial name
- VIDEOKIDS (NCT07495436)
- Testing
- Videolaryngoscope, Direct Laryngoscope
- Where
- Spain
- Volunteers
- 5,562 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Anesthesia, Blood Pressure
Norepinephrine Prevent Post-induction Hypotension in High-risk Patients
The investigators aimed to investigate the effects of continuous infusion of norepinephrine before and after general anesthesia induction on the occurrence of post-induction hypotension.
- Conditions
- Anesthesia, Blood Pressure, Norepinephrine
- Trial name
- NCT06028256
- Testing
- Norepinephrine Hydrochloride
- Volunteers
- 180 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
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