Clinical trials: Global Surgery
Cerebral Perfusion, Cerebral Oxygenation
Evaluation of Cerebral Oxygenation During Orthopedic Surgeries Performed in the Beach Chair Position Under General Anesthesia
The goal of this observational study is to determine the correlation between cerebral oxygenation values measured by near-infrared spectroscopy (NIRS) and other routine monitoring parameters in patients placed in the semi-sitting…
- Conditions
- Cerebral Perfusion, Cerebral Oxygenation, Hemodynamic Monitoring, Semi-sitting Position
- Trial name
- NCT07270341
- Testing
- Near-Infrared Spectroscopy (NIRS) Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Akdeniz University
Distal Radius Fracture, Postoperative Pain
Regional or General Anesthesia for Distal Radius Fracture Surgery in a Day Surgery Setting
The purpose of this study is to compare general and regional anesthesia with regard to postoperative pain in patients who undergo surgery in a day surgery setting due to a displaced distal radius fracture.
- Trial name
- NCT02495688
- Testing
- Regional anesthesia, General anesthesia
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Anesthesia, General
Brainwave Entrainment During Emergence
The investigators will compare whether there is a significant difference in the time required for general anesthesia recovery according to application of the binaural sound after surgery.
- Trial name
- BB_emergence (NCT05736510)
- Testing
- Binaural sound, Control
- Where
- South Korea
- Volunteers
- 106 people
- Sponsor
- Seoul National University Hospital
Anesthesia, General, Laparoscopic Surgery
Effect of Preoperative Pregabalin on Propofol Induction Dose
The primary issue is to determine whether preoperatively administered pregabalin decreases the necessary dose of propofol during induction of general anesthesia.
- Trial name
- NCT01158859
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Inguinal Hernia, Groin Hernia
A Global Prospective Study on Inguinal Hernia Surgery
The primary aim of the HIPPO study is to identify compliance to audit standards (pre-operative and intraoperative) standards for the repair and management of inguinal hernia.
- Conditions
- Inguinal Hernia, Groin Hernia, Surgery
- Trial name
- HIPPO (NCT05748886)
- Where
- United Kingdom
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Patients With Breast Cancer and Breast Surgery Requiring
Assessment of Cognitive Function After Surgery in Two Types of Anesthesia in Patients Operated for Breast Cancer
The emergence of cognitive disorders after surgery under general anesthesia (GA) is the second leading cause of patient complaints (after dental debris caused by intubation techniques).
- Trial name
- HYPNOSEIN (NCT01880541)
- Testing
- hypnosedation, general anesthésia
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- Institut Bergonié
Pain Management, Regional Anesthesia
Revision of Deep Brain Stimulator in Patients With Parkinson's Disease
Parkinson's disease is a chronic and progressive neurodegenerative disease that affects the central nervous system, particularly impairing movement control.
- Conditions
- Pain Management, Regional Anesthesia, Deep Brain Stimulation, Parkinsons Disease
- Trial name
- NCT07176494
- Testing
- Patients who underwent surgery under general anesthesia, Patients who underwent surgery under regional anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara Etlik City Hospital
Hernia, Inguinal
Transinguinal Periperitoneal Technique in Inguinal Hernioplasty
evaluation of feasibility and efficacy of trans inguinal periperitoneal technique by using conventional mesh inguinal hernia repair in general surgery department in Assiut university hospitals
- Trial name
- NCT06270472
- Testing
- hernioplasty
- Volunteers
- 20 people
- Sponsor
- Assiut University
Anesthesiology, General Surgery
The Effect of Enhanced Recovery After Surgery (ERAS) in Gastric Cancer Surgery
The investigators aimed to clarify the clinical relevance of the ERAS protocol by evaluating the perioperative course in patients undergoing laparoscopic gastric cancer surgery.
- Trial name
- NCT06209983
- Testing
- ERAS, Conventional care
- Where
- Taiwan
- Volunteers
- 38 people
- Sponsor
- National Taiwan University Hospital
Orthognathic Surgery, Maxillofacial Abnormalities
Study Evaluating the Performance and Safety of Global D Implants Indicated for Orthognathic Surgery
This study is set up within the framework of the European Union regulation 2017/745 on medical devices. Its objective is to confirm the performance and safety of the Global D implants (ORTRAUTEK® and MINITEK®) used for…
- Conditions
- Orthognathic Surgery, Maxillofacial Abnormalities, Maxilla Fracture
- Trial name
- CMF-ORTHO (NCT05271383)
- Testing
- Orthognathic surgery using Global D's implants.
- Where
- France
- Volunteers
- 198 people
- Sponsor
- Global D
Anorectal Disorder
Urine Retention Rate Between Spinal and General Anesthesia for Anorectal Surgery
Anorectal surgery includes pilonidal sinus, hemorrhoidectomy, anal fissure, and anal fistula operations. General and spinal anesthesia were common anesthetic methods in anorectal surgery.
- Trial name
- NCT05571202
- Testing
- General anesthesia plus local infiltration, Spinal anesthesia
- Where
- Taiwan
- Volunteers
- 1,400 people
- Sponsor
- Taichung Veterans General Hospital
Anxiety State, Child Behavior
Effects of Different Parental Involvement on Anxiety and Delirium
Induction of anesthesia in surgical procedures can be a distressing process for both children and their parents. Nonpharmacological behavioral interventions, unlike sedative medications, can reduce children's anxiety without…
- Trial name
- NCT06634680
- Testing
- Procedure: Selection of parent(mother or father) according to children preference, Procedure: Both parents will accompany the children.
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Chronic Periodontitis
Serum TRAP-5b Levels in Patients With Generalized Chronic Periodontitis
To compare the effect of non-surgical periodontal therapy with or without systemic administration of amoxicillin and metronidazole on the concentration of serum levels of TRAP-5b in patients with generalized chronic periodontitis.
- Trial name
- NCT03043066
- Testing
- Scaling and root planing, scaling and root planing along with antibiotic intervention
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Burst Suppression, Electroencephalogram
Impact of Interscalene Block Combined With General Anesthesia on Burst Suppression in Shoulder Surgery Patients
This prospective, randomized, double-blind clinical study aimed to investigate the effects of combining general anesthesia with an interscalene brachial plexus block (ISB) on burst suppression ratio (BSR) and…
- Conditions
- Burst Suppression, Electroencephalogram, Interscalene Brachial Plexus Block
- Trial name
- NCT07081672
- Testing
- Ultrasound-guided interscalene brachial plexus block (ISB), General Anesthesia (control group)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bezmialem Vakif University
Anesthesia, General
Evaluation of Volatile Induction and Maintenance Anesthesia (VIMA) With Sevorane in Adult Patients Requiring General Anesthesia for Surgery in Terms of Quality of Anesthesia and Its Influence on the Cardiovascular System in Common Clinical Practice
The main objective of this post-marketing observational study (PMOS) is to collect data of using general anesthesia in patients undergoing any surgery to create local recommendations.
- Trial name
- SEVOPROTECTION (NCT01282086)
- Where
- 10 sites in Ukraine
- Volunteers
- 1,365 people
- Sponsor
- Abbott (Ukraine)
Colon Cancer, Anesthesia
General Anesthesia or Combined Spinal-epidural Anesthesia With Ketofol Sedation in Colon Cancer Surgery?
Anesthesia management in colon cancer surgery affects the postoperative mobilization, discharge and oral intake times of the patients.
- Trial name
- NCT05334251
- Testing
- combined spinal-epidural anesthesia
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Anesthesia
Japan Phase 2/3 Clinical Study With BLM-240 (Desflurane)
The purposes of this study are to evaluate the efficacy and safety of desflurane (BLM-240) as an anesthetic agent and to demonstrate the non-inferiority of desflurane to sevoflurane in term of awakening/recovery from anesthesia.
- Trial name
- NCT00762372
- Testing
- desflurane, desflurane/nitrous oxide, sevoflurane/nitrous oxide
- Where
- 15 sites in Japan
- Volunteers
- 216 people
- Sponsor
- Baxter Healthcare Corporation
Postoperative Delirium
Prevention of Postoperative Delirium After Acute Surgery
The aim of this trial is to evaluate the implementation and effect of an evidence based, multicomponent intervention on postoperative delirium, when fast implemented throughout the patients stay in hospital before, during and…
- Trial name
- POD-CARE (NCT04857125)
- Testing
- Patient interventions, Staff education
- Where
- Denmark
- Volunteers
- 476 people
- Sponsor
- Bispebjerg Hospital
Laparoscopic Surgical Procedures, Airway Control
Evaluation of SaCo VLMA for General Anesthesia for Laparoscopic Procedures
Evaluation of new supraglottic device SaCo VLMA for laparoscopic procedures under general anesthesia in comparison with other airway management methods including other supraglottic devices.
- Conditions
- Laparoscopic Surgical Procedures, Airway Control, Anesthesia
- Trial name
- NCT07391969
- Testing
- SaCo VLM or SAD or ET for airway control for laparoscopy
- Volunteers
- 20 people
- Sponsor
- Medical University of Lodz
Anesthesia Airway Management, Respiratory Complications
Deflated and Inflated Cuff Endotracheal Extubations
General anesthesia is a treatment with medicine to make a patient unconscious for surgery. This is sometimes called "being put to sleep" or "being put under." Most of the time, a breathing tube is used to help a machine breathe…
- Trial name
- DICEE (NCT06990308)
- Testing
- Inflated Cuff Extubation, Deflated Cuff Extubation
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Naval Medical Center Camp Lejeune
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