Clinical trials: Global Surgery
Postoperative Morbidity, Postoperative Mortality
Hemostasis Evolution During Fluid Loading in Abdominal Surgery. Effects of Fluid Choice: Saline Versus Hydroxyethyl Starch (HAEMO Study)
The primary purpose of the study is to evaluate whether the type of fluid (0.9% saline or 6% Hydroxyethyl starch 130/0.4) in the context of an individualized goal-directed fluid therapy is associated with a difference in…
- Conditions
- Postoperative Morbidity, Postoperative Mortality, Hemostasis Change
- Trial name
- HAEMO (NCT03420261)
- Testing
- 0.9% saline, HES 130/0.4
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Clermont-Ferrand
Inguinal Hernia, Groin Hernia
A Global Prospective Study on Inguinal Hernia Surgery
The primary aim of the HIPPO study is to identify compliance to audit standards (pre-operative and intraoperative) standards for the repair and management of inguinal hernia.
- Conditions
- Inguinal Hernia, Groin Hernia, Surgery
- Trial name
- HIPPO (NCT05748886)
- Where
- United Kingdom
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Postoperative Pain, Open Abdominal Surgery
Erector Spinae Plane Block for Pain Control After Open Abdominal Surgery
his randomized controlled trial aims to evaluate the efficacy of the bilateral erector spinae plane (ESP) block in reducing postoperative opioid consumption in patients undergoing open abdominal surgeries under general anesthesia
- Trial name
- NCT07479069
- Testing
- Bilateral Erector Spinae Plane (ESP) Block, Standard Postoperative Analgesia
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Fatima Memorial Hospital
Pain, Postoperative
Biobehavioral Recovery From Surgery and Anesthesia
Reducing postoperative pain leads to increased patient comfort and facilitates speedy recovery and discharge from the hospital following surgery.
- Trial name
- NCT00176696
- Testing
- Use of FACE monitor and BIS monitor
- Volunteers
- 20 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Anesthesia, General, Gynecologic Surgical Procedures
DSA vs. BIS for Anesthesia and Analgesia Management
The purpose of this study is to compare two different methods of monitoring brain activity (anesthesia depth) during gynecological surgeries.
- Conditions
- Anesthesia, General, Gynecologic Surgical Procedures, Intraoperative Monitoring, Anesthesia Depth Monitoring
- Trial name
- DSA-PRECISION (NCT07502261)
- Testing
- Density Spectral Array (DSA) Monitoring, Bispectral Index (BIS) Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Surgical Procedure, Unspecified
Bucatini Pasta, Japanese Shirataki Konjac Noodles, and Artificial Vessels: In Search of the Ideal Low-cost Vessel Simulator for Microsurgical Education
The aim of this study is to assess the strengths and weaknesses of training models that are accessible, reproducible, and geared toward new learners.
- Trial name
- NCT07006766
- Testing
- Microsurgical Training Models
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Nasolabial Fold Correction, Facial Aging
Bridging Technique Validation for Nasolabial Folds JN-BRIDGE-1
The goal of this clinical study is to learn whether the Bridging Technique can safely and effectively treat nasolabial folds (NLF, also known as smile lines) in adults.
- Conditions
- Nasolabial Fold Correction, Facial Aging, Skin Rejuvenation, Wrinkles Such as Nasolabial Folds
- Trial name
- BRIDGING (NCT07178119)
- Testing
- (Bridging) Horizontal Cannula Technique for Treatment of Nasolabial Folds using AILEENE Vol. 2
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Joseph M Novoa Libermann
Hip Fractures
Hypobaric Lateral Spinal Anesthesia Versus General Anesthesia for the Hip Fracture Surgery
Hip fracture is a frequent pathology, involving elderly patients with many co-morbidities ; therefore, post-operative morbidity and mortality is high.
- Trial name
- RACHYP (NCT03373864)
- Testing
- Unilateral spinal anesthesia, General anesthesia
- Where
- France
- Volunteers
- 154 people
- Sponsor
- Hospices Civils de Lyon
Anesthesia
Efficacy and Safety of HSK3486 Compared to Propofol in Induction of General Anesthesia in Adults Having Elective Surgery
This is a multicenter, randomized, double-blinded, propofol-controlled, Phase 3 clinical study to evaluate the efficacy and safety of HSK3486 for induction of general anesthesia in adults undergoing elective surgery.
- Trial name
- NCT04711837
- Testing
- HSK3486, Propofol
- Where
- 13 sites in United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Haisco-USA Pharmaceuticals, Inc.
Limit Emergence Phenomena After General Anesthesia
Limiting Emergence Phenomena After General Anesthesia With Combined LMA and ETT Airway Management Technique
Emergence from general anesthesia with a laryngeal mask airway compared with an endotracheal tube has been shown to favorable with respect to limiting emergence phenomena such as coughing, straining, restlessness, and sympathetic…
- Trial name
- LEPAGA (NCT02708836)
- Testing
- Induction of anesthesia, Placement of LMA [Ambu (R) AuraGain (TM) disposable laryngeal mask], Laryngoscopy and placement of ETT
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Milton S. Hershey Medical Center
Hypotension
Vasopressor Outcomes in Spine Surgery
This is a prospective, randomized control trial comparing norepinephrine versus phenylephrine for vasopressor support in patients undergoing elective spinal fusion surgery.
- Trial name
- V-SPINE (NCT06053398)
- Testing
- Phenylephrine, Norepinephrine
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of Texas Southwestern Medical Center
General Surgery With Endotracheal Intubation
The Effect Site Concentration of Remifentanil for Preventing QTc Interval Prolongation During Intubation Under Propofol-remifentanil Anesthesia in Elderly Patients
To find out the effect site concentration of remifentanil for preventing QTc interval prolongation during intubation under propofol-remifentanil anesthesia in elderly patients
- Trial name
- NCT01720498
- Testing
- remifentanil
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Severance Hospital
Bariatric Surgery, Anesthesia, General
Predictors of Anesthesia Complications in Patients Undergoing Bariatric Surgery
This study aims to identify factors that can predict complications related to anesthesia in patients undergoing weight-loss surgery.
- Conditions
- Bariatric Surgery, Anesthesia, General, Postoperative Complications, Obesity
- Trial name
- NCT06981793
- Where
- France
- Volunteers
- 125 people
- Sponsor
- Centre Hospitalier de Gonesse
Telemedicine, General Surgery
Comparative Study Between Conventional and Telematic Patients Follow-up
This is a parallel group clinical trial comparing two types of follow-up in patients operated and treated in a General and GI surgery department.
- Conditions
- Telemedicine, General Surgery, Outpatients
- Trial name
- TLM-CGD (NCT03304509)
- Testing
- Telematic follow-up
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Germans Trias i Pujol Hospital
Day Surgery
Ramosetron OD Tablet and Postdischarge Nausea and Vomiting
Postoperative nausea and vomiting after general anesthesia is one of the common anesthetic complications. If the patient is discharged from the hospital after surgery, proper treatment may be delayed or impossible if nausea and…
- Trial name
- NCT04297293
- Testing
- Ramosetron
- Where
- South Korea
- Volunteers
- 138 people
- Sponsor
- Seoul National University Hospital
Cerebral Ischemia
Impact of Interscalene Nerve Block on Cerebral Perfusion During Surgery in the Beachchair Position
Beachchair position is used by many orthopaedic surgeons for shoulder surgery. Most patients undergoing surgery in this position have no complications.
- Trial name
- NCT01983618
- Testing
- Interscalene nerve block and catheter, Interscalene catheter
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
General Anesthesia
Gastric Ultrasound in Paediatric Anaesthesia
Anesthesia for emergency surgery is a situation at risk of pulmonary aspiration of gastric contents. It has been previously reported that bedside two-dimensional ultrasonography can be a useful tool for anesthesiologists to…
- Trial name
- ECHOGASTRO (NCT02584348)
- Testing
- Gastric ultrasound
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Hospices Civils de Lyon
Evisceration; Traumatic, Eye
Quality Of Life After Eye Surgical Removal
Studies have shown that health-related quality of life (HRQOL) was worse among patients who underwent surgical eye removal compared to the general population in Denmark.
- Trial name
- QOLAE (NCT05397743)
- Testing
- Quality of Life
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Abdomen, Acute
Clinical Outcomes and Equality in Healthcare for Emergency General Surgery Patients Undergoing Emergency Laparotomy
The goal of this observational cohort study is to evaluate the standard of care for general surgerical patients undergoing emergency laparotomy and assess factors affecting clinical outcomes, as well as evaluating the quality of…
- Trial name
- LAPTOP (NCT05623176)
- Testing
- Standardised laparotomy care
- Where
- Sweden
- Volunteers
- 2,000 people
- Sponsor
- Region Stockholm
Laparoscopic Cholecystectomy Surgery
Beneficial Effects of Low-Dose Intravenous Dexmedetomidine Premedication in Patient Undergoing Laparoscopic Cholecystectomy Under General Anesthesia
Laparoscopic cholecystectomy (LC) is considered the standard treatment for gallbladder disease.1 Compared to open cholecystectomy, LC is the preferred treatment approach because it is associated with less surgical trauma, shorter…
- Trial name
- NCT06838650
- Testing
- Dexmedetomidine, Saline
- Volunteers
- 100 people
- Sponsor
- Assiut University
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