Clinical trials: Global Surgery
Emergency Surgery, Surgical Site Infections
Irrisept in Emergency General Surgery Patients
This is a single institution, randomized study conducted to determine if irrigation with Irrisept in emergency general surgery patients results in lower surgical site infections compared to normal saline irrigation.
- Trial name
- NCT07048899
- Testing
- Chlorhexidine, Normal Saline
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- The University of Texas Health Science Center at Tyler
Neuromuscular Blockade
Safety and Efficacy of HRS-9190 Compared to Rocuronium for Tracheal Intubation and Bolus Maintenance in Adults
The study will enroll adult patients scheduled for elective surgery requiring general anesthesia. Participants will be randomly assigned to receive either HRS-9190 for Injection or Rocuronium.
- Trial name
- NCT07746726
- Testing
- HRS-9190, Rocuronium
- Where
- 2 sites in China
- Volunteers
- 320 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Posterior Fossa Tumor
Partial Scalp Block in Posterior Fossa Surgery
Pain in patients undergoing posterior fossa surgery is regarded as more intense when compared to pain in patients undergoing supratentorial cranial surgeries.
- Trial name
- NCT04955236
- Testing
- Partial scalp block, Fentanyl
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kasr El Aini Hospital
Postoperative Sore Throat
Comparison of Nebulized Ketamine With Nebulized Magnesium Sulfate for the Prevention of Postoperative Sore Throat
The aim of this study is to compare the efficacy of nebulized ketamine versus nebulized magnesium sulfate in reducing the incidence and severity of POST. Primary outcome To compare the incidence of POST method.
- Trial name
- NCT07381036
- Testing
- Ketamine nebulizer, Mg sulfate nebulizer
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sohag University
General Anesthesia
Interest of the Study of Electroencephalogram and Peripheral Vegetative Markers for the Evaluation of Nociception Under General Anesthesia.
General anesthesia (GA) is a state of loss of consciousness induced by anesthetic products. In a GA, two classes of products are usually used: on the one hand, hypnotics that are responsible for the sleep component (hypnosis) and…
- Trial name
- BRAIN (NCT03994887)
- Testing
- Experimental group
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Emergencies
COVID-19 Pandemic and General Surgery Emergencies
A retrospective analysis of emergency general surgical admissions during the first six months of the pandemic (from March 11 to September 11, 2020) and the same period in 2019, will be conducted.
- Trial name
- NCT04686708
- Testing
- Emergency general surgical admissions
- Where
- Turkey (Türkiye)
- Volunteers
- 750 people
- Sponsor
- Gulhane Training and Research Hospital
Postoperative Pain
Effect of Noise Blocking During General Anesthesia on Postoperative Pain
To investigate the effect of noise blocking during general anesthesia on postoperative pain in patients undergoing laparoscopic abdominal surgery.
- Trial name
- NCT05540691
- Testing
- Wear noise-cancelling earphones
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Rotator Cuff Tear, Shoulder Surgery
Interscalene Brachial Plexus Block and Early Wound-Related Symptoms After Open Rotator Cuff Repair
This exploratory randomized controlled trial evaluated the association of interscalene brachial plexus block (ISB) with early postoperative wound-related symptom scores and perioperative biomarker responses in patients undergoing…
- Conditions
- Rotator Cuff Tear, Shoulder Surgery, Postoperative Recovery
- Trial name
- NCT05499897
- Testing
- Ultrasound-Guided Interscalene Brachial Plexus Block, General Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Yuzuncu Yil University
Type 2 Diabetes
Exenatide Inpatient Trial: A Randomized Controlled Pilot Trial on the Safety and Efficacy of Exenatide (Byetta®) Therapy for the Inpatient Management of Patients With Type 2 Diabetes
The purpose of this study is to try and achieve similar glycemic control in general non-Intensive Care Unit (non-ICU) patients with Type 2 Diabetes with exenatide alone or in combination with basal insulin as compared to…
- Trial name
- NCT02455076
- Testing
- Exenatide, Glargine, Rapid-acting insulin analogs
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Emory University
Postoperative Complications
Predictive Model for Postoperative Mortality
Surgery has risk of morbidity and mortality. Risk factors include: patient factors; surgical factors; and anesthetic factors. The risk is much higher in emergency cases.
- Trial name
- NCT02947789
- Testing
- Emergency surgery
- Where
- Thailand
- Volunteers
- 740 people
- Sponsor
- Khon Kaen University
Surgery
Comparison of Blood Pressure Measurements in Upper and Lower Extremities in Children Under General Anesthesia
There is very little information comparing non-invasive blood pressure (BP) readings obtained from upper and lower limbs, as well as comparing invasive and non-invasive blood pressures in the children under anesthesia.
- Trial name
- NCT03220906
- Testing
- Blood pressure measurement
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Nationwide Children's Hospital
Sepsis, Hypotension
Pre-induction Norepinephrine in Septic Patients Undergoing Surgery
This randomized controlled trial aims to evaluate the effect of early pre-induction norepinephrine infusion on perioperative hemodynamic stability in septic patients with SOFA score ≥2 undergoing surgery under general anesthesia.
- Trial name
- NCT07869693
- Testing
- Norepinephrine, Standard Care
- Volunteers
- 90 people
- Sponsor
- Assiut University
Vasopressor Agents, Endarterectomy, Carotid
Comparison of the Effects of Phenylephrine and Norepinephrine on Cardiac Function During Carotid Artery Surgery
This will be a prospective, randomized, double-blinded, cross-over clinical trial to compare the effects of phenylephrine or norepinephrine on cardiac function during carotid artery surgery in patients under general anesthesia.
- Conditions
- Vasopressor Agents, Endarterectomy, Carotid, Echocardiography, Transesophageal
- Trial name
- NCT00294606
- Testing
- Comparison of Effects of Phenylephrine and Norepinephrine
- Where
- Canada
- Volunteers
- 86 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Global Surgery, Global Health
Google Trends of Global Surgery
Introduction Global surgery is a growing movement worldwide, but its expansion has not been quantified. Google Search is the most popular search engine worldwide, and Google Trends analyzes its queries to determine popularity…
- Trial name
- NCT05012085
- Testing
- Investigation of Global Interest in Global Surgery
- Where
- Cameroon
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Association of Future African Neurosurgeons, Yaounde, Cameroon
Elective Surgery of Short Duration (Less Than 2 hr) Undergoing General Anesthesia Using Supraglottic Airway
The Comparison of the Clinical Efficacy Between I-gel and LMA-Supreme, the Two Most Recently Developed Supraglottic Airway Devices, in Infants
Although the safety and efficacy of the I gel in children has been shown in several large observational studies, There is no study about comparison of the clinical efficacy between I-gel and LMA-Supreme , in particular sizes 1…
- Trial name
- NCT01863316
- Testing
- I gel, LMA Supreme
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Periodontitis Chronic Generalized Severe, Intrabony Periodontal Defect
Clinical and Radiograhic Evaluation of NIPSA With and Without Allograft Plus Platelet Rich Fibrin in the Treatment of Intraosseous Defects in Stage III Periodontitis Patients
Several minimal invasive techniques have been proposed since the last decade aiming to enhance and provide adequate environment for periodontal regeneration.
- Trial name
- NCT04444063
- Testing
- Non-Incised Papilla Surgical Approach
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cerebral Hypoxia, Postoperative Delirium
Sevoflurane Decreases the Risk of Postoperative Delirium After Cerebral Hypoxemia During Surgery
The aim of this study is to distinguish possible differences in frequency of delirium after Volatile Induction and Maintenance of Anesthesia and Total Intravenous Anesthesia in case of undeliberate cerebral desaturation during…
- Trial name
- NCT02133638
- Testing
- Sevoflurane, Propofol
- Where
- Russia
- Volunteers
- 130 people
- Sponsor
- Negovsky Reanimatology Research Institute
Surgical Patients
The Impact of Clinical Pharmacist in the Identification and Management of Treatment Related Problems in the Surgery Ward
Patients in the surgery ward are at risk of morbidity and mortality from various types of treatment-related problems (TRPs). The primary aim of this study is to assess the impact of the clinical pharmacist in the identification…
- Trial name
- NCT04941820
- Testing
- clinical pharmacist intervention
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Surgical Complication, Emergencies
Implementation of an Epidemiological and Clinical Registry of Emergency Surgery Patients in a Costa Rican Hospital
A retrospective cross-sectional study was conducted in a quaternary level university hospital of the Costa Rican public health system.
- Trial name
- NCT05930574
- Testing
- Abdominal surgery
- Where
- Costa Rica
- Volunteers
- 575 people
- Sponsor
- Caja Costarricense de Seguro Social
Breast Neoplasms
The Application of Pectoral Nerve II(PECS II)block in Breast Fibroadenoma Resection Surgery
Patients were randomly assigned to the GA group, PECS II group, or TPVB group using a computer-generated random number table. Group assignments were kept in a sealed envelope, which was opened only after induction of general…
- Trial name
- PECS II (NCT06608810)
- Testing
- nerve block with 0.5% ropivacaine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Inner Mongolia Baogang Hospital
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