Clinical trials: Global Surgery
Surgery, Vascular Diseases
NMES for Rehab After Surgery
A randomised pilot study assessing the acceptability and feasibility of utilising neuromuscular stimulation devices to enhance post-operative rehabilitation and recovery after general, vascular and urological surgery procedures.
- Trial name
- NCT04784962
- Testing
- Revitive Medic Neuromuscular Stimulation Device
- Where
- United Kingdom
- Volunteers
- 103 people
- Sponsor
- Imperial College London
Pain, Postoperative
US-guided Thoracic Spinal Epidural Anesthesia VS GA for Abdominal and Breast Surgeries
Ultrasound-guided combined thoracic segmental spinal epidural anesthesia in comparison with general anesthesia in upper abdominal and breast surgery.
- Trial name
- NCT05587608
- Testing
- combined thoracic segmental spinal epidural anesthesia
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- South Egypt Cancer Institute
Airway Management, Tracheal Intubation
Effect of Night Shift Versus Daytime Duty on Tracheal Intubation Complications and Duration in Surgical Patients
Airway management is one of the most critical steps of anesthesia, and its complications can be life-threatening. Reduced staffing, differences in personnel experience, and physical and mental fatigue during off-hours (evenings…
- Conditions
- Airway Management, Tracheal Intubation, Intubation Complications, General Anesthesia
- Trial name
- NCT07823179
- Testing
- Tracheal Intubation
- Volunteers
- 1,000 people
- Sponsor
- Merve Yazici Kara
Shoulder Injuries, Shoulder Osteoarthritis
The Effects of General Anesthesia and Combined Anesthesia in Controlled Hypotension During Arthroscopic Shoulder Surgery
Controlled hypotension is one of the important techniques used for facilitates the clarity of the surgical field during arthroscopic shoulder surgery.
- Trial name
- NCT05451550
- Testing
- Brachial plexus block, General anesthesia, Suprascapular nerve block
- Where
- China
- Volunteers
- 100 people
- Sponsor
- General Hospital of Ningxia Medical University
General Anesthesia, Testosterone
Comparison of the Effect of Testosterone Administered for Micropenis Hypospadias Surgery With Bispectral Index
The aim of this observational study is to learn the effects of hormone therapy (testosterone) applied in micropenis hypospadias surgery on the depth of anesthesia under general anesthesia.
- Conditions
- General Anesthesia, Testosterone, BIS
- Trial name
- NCT06606496
- Testing
- Bispectral index (BIS)
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Namik Kemal University
Supratentorial Neoplasms, Anesthesia, General
Effect of PEEP on Subdural Pressure, Optic Nerve Sheath Diameter, Lung Compliance and Brain Perfusion Pressure
We aim to determine the level of intraoperative PEEP that optimizes lung compliance without causing a rise in subdural pressure and if we can utilize optic nerve sheath diameter measurement as an indicator for ICP while…
- Conditions
- Supratentorial Neoplasms, Anesthesia, General, Optic Nerve
- Trial name
- NCT04316208
- Testing
- PEEP variations
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Intraocular Pressure
Effect of Sevoflurane Concentration on Intraocular Pressure in Surgical Children With Healthy Eyes
One important goal in anesthetic management during ocular surgery is to provide adequate control of intraocular pressure (IOP). An increase in IOP may be catastrophic in patients with glaucoma or a penetrating open-eye injury.
- Trial name
- NCT01248689
- Testing
- concentration profile 1, concentration profile 2, concentration profile 3
- Where
- Israel
- Volunteers
- 21 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Surgery, Anaesthesia
Local Assessment of Ventilatory Management During General Anesthesia for Surgery
Objectives 1. To characterize mechanical ventilation practices during general anesthesia for surgery 2. To assess the dependence of intra-operative and post-operative pulmonary complications on intra-operative Mechanical…
- Conditions
- Surgery, Anaesthesia, Ventilator-Induced Lung Injury, Lung Injury
- Trial name
- LAS VEGAS (NCT01601223)
- Where
- 19 sites in United States, Estonia and 6 more
- Volunteers
- 10,690 people
- Sponsor
- European Society of Anaesthesiology
Orthopedic Surgery, General Anesthesia
Comparison Study of Intraoperative Patient Warming Systems
Medications used to put people to sleep during surgical procedures also cause changes in the body's ability to control its temperature. These changes can make a person's temperature drop below normal.
- Trial name
- NCT00670826
- Testing
- vitalHEAT vH2 Temperature Management System, Arizant Healthcare Bair Hugger Temperature Management System
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Dynatherm Medical Inc.
Postoperative Respiratory Complications
PROVHILO:Protective Ventilation During General Anesthesia for Open Abdominal Surgery
The purpose of this international, multicentre, double-blinded randomized controlled trial is to determine if the "open lung approach" providing recruitment maneuvers and PEEP(Positive End Expiratory Pressure) during general…
- Trial name
- PROVHILO (NCT01441791)
- Testing
- Lung protective strategy ventilation
- Where
- 30 sites in United States, Austria and 8 more
- Volunteers
- 900 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Gastro-Intestinal Disorder
Advanced GastroInstestinal(GI) Surgery Training in Residency and Fellowship.
The aim of this anonymous survey is to identify who teaches GI procedures to general surgical residents during residency training and understand the need as well as desire for an Advanced Surgical GI fellowship amongst senior…
- Trial name
- NCT07494318
- Testing
- Advanced GI Surgery Training
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Methodist Health System
Volume-Outcome Relationship in Pancreatic Surgery
Pancreatic Surgery - Optimal Caseload Thresholds and Predictive Accuracy
The main objective of the study is to identify the optimal annual number of cases in a hospital with regard to minimising hospital mortality in pancreatic surgery.
- Trial name
- PaSuT (NCT06389890)
- Testing
- Pancreatic resection procedure
- Volunteers
- 80,000 people
- Sponsor
- Richard Hunger
Gynecological Surgery, General Anesthesia
Heat and Moisture Exchanger and Low-flow Gas
The aim of the present study was to measure the inspired gas temperature and humidity of the anesthetic circuit in the Dräger Primus machine and esophageal temperature with or without and heat and moisture exchanger (HME) and…
- Trial name
- NCT00997295
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Lung Cancer, OLV
Spontaneous Breathing Mode: A Risk for Hypoxemia During OLV?
Patients undergoing thoracic surgery with one-lung ventilation (OLV) are prone to hypoxemia, which is primarily attributable to pulmonary ventilation-perfusion (V/Q) mismatch.
- Conditions
- Lung Cancer, OLV, Hypoxemia During Surgery
- Trial name
- OLV (NCT07494006)
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Peking University People's Hospital
Hip Fracture Surgery
Predicted Level of General Anaesthesia in Hip Fracture Surgery
The purpose of this study is to evaluate if prediction of general anaesthesia level by the Smartpilot® View device can improve the quality of anaesthesia in patients undergoing hip fracture surgery.
- Trial name
- NAPfem (NCT02556658)
- Testing
- General anesthesia managed by the Smartpilot® View, General anesthesia managed without the Smartpilot® View
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Orchiopexy
Comparison of Analgesic Efficacy of Fascia Transversalis Plan Block and Caudal Epidural Block in Pediatric Patients Undergoing Orchiopexy
Orchiopexy is a surgery with a high frequency in the pediatric population. The use of regional anesthesia techniques has become widespread and its importance has increased in order to provide more effective and prolonged…
- Trial name
- NCT07006844
- Volunteers
- 60 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Severe Mitral Regurgitation, Preserved Ventricular Ejection Fraction
Use of Pre-operative Global Longitudinal Strain to Predict Post-operative Left Ventricular Dysfunction in Mitral Regurgitation Surgery
Primary mitral regurgitation (MR) is the second most frequent valve disease requiring surgery and it is important to identify patients whose outcome could be improved with surgery by considering the risks and benefits.
- Trial name
- DysPO IM (NCT03968601)
- Testing
- Mitral regurgitation surgery such as mitral valve replacement or repair
- Where
- France
- Volunteers
- 79 people
- Sponsor
- University Hospital, Clermont-Ferrand
Benzodiazepines, Bladder Cancer
Impact of Remimazolam on Prognosis After Bladder Cancer Surgery
Bladder cancer is one of the most common genitourinary cancers. Transurethral resection of bladder tumor (TURBT) is the standard therapy for nonmuscle invasive bladder cancer.
- Conditions
- Benzodiazepines, Bladder Cancer, Delirium, Surgery
- Trial name
- NCT04532606
- Testing
- Remimazolam, Propofol
- Where
- 6 sites in China
- Volunteers
- 1,128 people
- Sponsor
- Peking University First Hospital
General Anesthesia, Sevoflurane
Efficacy and Safety of Sevofran in Patients Scheduled for Elective Surgery Under General Anesthesia
Sevoflurane is currently being used in more than 100 countries worldwide with an estimated 100 million operations having been performed using sevoflurane as a general anesthetic.
- Conditions
- General Anesthesia, Sevoflurane, Generic Drugs
- Trial name
- NCT01096212
- Testing
- original sevoflurane, generic sevoflurane
- Where
- 2 sites in South Korea
- Volunteers
- 178 people
- Sponsor
- Asan Medical Center
Hypotension on Induction
FloPatch for Prevention of Hypotension After Induction of General Anesthesia
This study is being conducted to find out if a special device called FloPatch™, which sticks to a persons skin and uses ultrasound to check the blood flow in their neck, can tell if someone going to have low blood pressure after…
- Trial name
- HI-CAP (NCT06316817)
- Testing
- FloPatch
- Where
- Canada
- Volunteers
- 172 people
- Sponsor
- Mount Sinai Hospital, Canada
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