Clinical trials: Glucose
Diabetes Mellitus, Type 2
Incidence of Type 2 Diabetes in the di@Bet.es Study
Our aim was to determine the incidence of type 2 diabetes mellitus in a nation-wide population based cohort from Spain (di@bet.es study). The target was the Spanish population.
- Trial name
- NCT02542735
- Where
- Spain
- Volunteers
- 2,408 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Metabolic Syndrome
Dairy Macronutrient Effects on the Metabolic Syndrome
The investigators examined the effects of 4-week dietary protein intake in mixed meals at two levels of protein amount on whole body glucose metabolisms in older adults with metabolic syndrome.
- Trial name
- NCT02885935
- Testing
- Recommended protein intake, Elevated protein intake
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Diabetes Mellitus, Type 2
Care Navigator Support for Younger Latinx Adults With Type 2 Diabetes
The study proposes to rigorously evaluate a proactive, culturally responsive care navigator intervention targeting younger-onset Latinx individuals with a new T2D diagnosis (AURORA [Active Outreach to Younger Latinx]) within…
- Trial name
- AURORA (NCT05754008)
- Testing
- AURORA Care Strategy
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Type 2 Diabetes
KPSC MNT Pilot RCT
The purpose of this pilot randomized trial is to evaluate the implementation and effectiveness of a Diabetes Medical Nutrition Therapy (DM MNT) program for adults with type 2 diabetes and poor glycemic control receiving care in a…
- Trial name
- DM MNT Pilot (NCT07868250)
- Testing
- Diabetes Medical Nutrition Therapy (DM MNT) Pilot
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Kaiser Permanente
Diabetic Nephropathy
Low-dose Colchicine in Patients With Type 2 Diabetes Mellitus and Microalbuminuria
1. The primary objective of this study was： in patients with type 2 diabetes and microalbuminuria who have been receiving stable treatment of angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker (ACEI/ARB) for…
- Trial name
- NCT02035891
- Testing
- colchicine 0.5mg/d
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Chongqing Medical University
Type 2 Diabetes
Mobile Phone Support for Adults and Support Persons to Live Well With Diabetes
This study evaluates a mobile phone-delivered intervention (FAMS 2.0; Family/friend Activation to Motivate Self-care) designed to help adults with type 2 diabetes set and achieve self-care goals and improve the quality of…
- Trial name
- FAMS 2 (NCT04347291)
- Testing
- FAMS 2.0, Print Materials
- Where
- United States
- Volunteers
- 638 people
- Sponsor
- Vanderbilt University Medical Center
Gestational Diabetes Mellitus
Exercise Intervention to Prevent Gestational Diabetes
This study evaluates the role of exercise intervention in reducing the risk of gestational diabetes mellitus(GDM) risk of overweight/obese(prepregnancy BMI≥24kg/m^2） Chinese pregnant women.
- Trial name
- NCT02304718
- Testing
- Stationary bike
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University First Hospital
Diabetes Mellitus
A Study on Effect of Health Promotion for Prevention NIDDM in People With Prediabetes
OBJECTIVE - The role of health promotion for patients with impaired fasting glucose on preventing or delay the progression of diabetes mellitus has not been widely investigated in Taiwan.
- Trial name
- NCT00257218
- Testing
- Life style modification
- Where
- Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Vitamin D Deficiency, HIV Infections
The Prevalence of Vitamin D Deficiency and Effects of Vitamin D Supplementation in HIV-1 Infected Patients
The purpose of this study is to determine the effect of normalization of vitamin D levels on bone density, immune and adipocyte function in HIV1-seropositive patients.
- Trial name
- NCT00306410
- Testing
- colecalciferol
- Where
- Netherlands
- Volunteers
- 85 people
- Sponsor
- Radboud University Medical Center
Type 2 Diabetes Mellitus
Saxagliptin Compared to Glimepiride in Elderly Type 2 Diabetes Patients, With Inadequate Glycemic Control on Metformin
This study will evaluate the efficacy and tolerability of saxagliptin compared to glimepiride in elderly patients with type 2 diabetes mellitus who have inadequate glycaemic control on metformin monotherapy.
- Trial name
- GENERATION (NCT01006603)
- Testing
- Saxagliptin, Glimepiride
- Where
- 131 sites in Austria, Denmark and 11 more
- Volunteers
- 957 people
- Sponsor
- AstraZeneca
Diabetes, Coronary Artery Calcification
A Study Comparing Skin Fluorescence to Coronary Artery Calcification
This study examines the relationship between the SCOUT DM device and coronary artery calcification as determined by rapid computed tomography in patients at risk for coronary heart disease.
- Trial name
- CACS (NCT00895427)
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- VeraLight, Inc.
Cardiovascular Diseases, Coronary Disease
Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
To determine if the combined incidence of nonfatal myocardial infarction and coronary heart disease death differs between diuretic-based and each of three alternative antihypertensive pharmacological treatments.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Diabetes Mellitus, Heart Diseases
- Trial name
- NCT00000542
- Testing
- Inhibitors, ACE, amlodipine, lisinopril
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Type 1 Diabetes Mellitus, Lipohypertrophy
Innovative Insulin Injection Sites Map to Minimize Lipohypertrophy Risk
Background: Patients on long-term insulin therapy frequently develop a condition called lipohypertrophy (LH), which involves the accumulation of abnormal fatty tissue at insulin injection sites.
- Trial name
- NCT07561086
- Testing
- Insulin Injection Site Mapping Tool
- Where
- Egypt
- Volunteers
- 170 people
- Sponsor
- Helwan University
Hypoglycemia
Analysis of Related Risk Factors of Hypoglycemia Consciousness Disorder
Objective to explore the high risk factors and inducements of consciousness disorder in patients with hypoglycemia, and to conduct a retrospective study.
- Trial name
- NCT04971070
- Testing
- Observation and follow-up
- Where
- China
- Volunteers
- 292 people
- Sponsor
- Chongqing Renji Hospital, University of Chinese Academy of Sciences
Genetic Predisposition to Disease, Hyperglycemia
TCF7L2 Polymorphisms Influence on Glycemic Control in ICU Patients With Organ Failure
This study evaluates the link between genetic polymorphisms as r7903146, rs12255372 of TCF7L2 gene and the risk of developing hyperglycemia during Intensive care unit stay
- Conditions
- Genetic Predisposition to Disease, Hyperglycemia, Intensive Care Unit Syndrome, Multiple Organ Failure
- Trial name
- READIAB-G4 (NCT03055169)
- Testing
- genetic analysis, blood and stools samples
- Where
- 5 sites in France
- Volunteers
- 994 people
- Sponsor
- University Hospital, Lille
Diabetes, Diabetes Mellitus, Type 1
Comparison of Single Dose and Steady State Pharmacodynamics of Biphasic Insulin Aspart 30 and 70 in Subjects With Type 1 Diabetes
This trial is conducted in Europe. The aim of this trial is to compare the single dose and steady state pharmacodynamics of biphasic insulin aspart 30 and biphasic insulin aspart 70 in subjects with type 1 diabetes.
- Trial name
- NCT01526941
- Testing
- biphasic insulin aspart 30, biphasic insulin aspart 70
- Where
- Germany
- Volunteers
- 27 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 2
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Subcutaneous Injections of HRS9531 in Patients With Type 2 Diabetes Mellitus
The main purpose of this study is to assess the safety and tolerability of multiple subcutaneous injections of HRS9531 in patients with type 2 diabetes mellitus who have suboptimal glycaemic control after conventional lifestyle…
- Trial name
- NCT05516966
- Testing
- HRS9531, Dulaglutide Injection
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Prediabetic State, Diabetes type2
Effect of Totum-63 on Glucose and Lipid Homeostasis in Subjects With Dysglycemia (REVERSE-IT)
This clinical study aims to assess the efficacy of TOTUM-63, a mix of 5 plant extracts, consumed at the daily regimen of three times per day on glucose and lipid homeostasis in dysglycemic subjects.
- Conditions
- Prediabetic State, Diabetes type2, Dysglycemia
- Trial name
- REVERSE-IT (NCT04423302)
- Testing
- TOTUM-63 3 intakes per day, TOTUM-63 2 intakes per day
- Where
- 52 sites in Bulgaria, France and 5 more
- Volunteers
- 636 people, healthy volunteers welcome
- Sponsor
- Valbiotis
Diabetes Mellitus, Type 2
Empa PASS on Urinary Tract Malignancies
The aim of the study is to assess the risk of urinary tract malignancies in patients initiating empagliflozin (free or fixed dose combination) compared to patients initiating a dipeptidyl peptidase-4 (DPP-4) inhibitor.
- Trial name
- NCT03464045
- Testing
- empagliflozin, DPP-4 inhibitors
- Where
- 3 sites in Finland, Sweden and 1 more
- Volunteers
- 344,995 people
- Sponsor
- Boehringer Ingelheim
Vascular Stiffness, Hypoglycemic Agents
The Effects of Empagliflozin on Arterial Wall Characteristics
Introduction: Diabetes mellitus is characterized by impaired arterial function and high incidence of cardiovascular events. Metformin and most recent antidiabetic groups of drugs, SGLT2 inhibitors, were in previous studies shown…
- Conditions
- Vascular Stiffness, Hypoglycemic Agents, Diabetes Complications, Diabetes Mellitus, Type 1
- Trial name
- NCT03639545
- Testing
- Empagliflozin 25mg, Metformin, Empagliflozin/Metformin
- Where
- Slovenia
- Volunteers
- 120 people
- Sponsor
- University Medical Centre Ljubljana