Clinical trials: Glucose Metabolism
Diabetes
Multi-day (3) In-patient Evaluation of Intradermal Versus Subcutaneous Basal and Bolus Insulin Infusion
The primary objective of this study is to investigate if intradermal (in the skin) basal and bolus insulin delivery of a fast acting insulin analog (NovoRapid) as needed to adequately control the blood glucose for a subject with…
- Trial name
- NCT01557907
- Testing
- Subcutaneous delivery via Medtronic Quick-Set, Intradermal delivery via the BD Research Catheter Set
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- Becton, Dickinson and Company
Diabetes Mellitus, Type 2
MATCH: The Mexican-American Trial of Community Health Workers
The MATCH study (Mexican-American Trial of Community Health Workers) tests the hypothesis that the use of indigenous Community Health Workers (CHWs), recruited from the target community and trained to provide culturally…
- Trial name
- MATCH (NCT01067092)
- Testing
- Community Health Worker Intervention, Educational Newsletter
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Rush University Medical Center
Diabetes, Peripheral Neuropathy
Metanx Effects on Nerve Fiber Density in Neuropathic Diabetics
This study focuses on the use of Metanx® as the sole treatment for improving and reversing nerve damage in type 2 diabetic patients with peripheral neuropathy.
- Trial name
- SLHN2011-18 (NCT01503892)
- Testing
- Metanx
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital and Health Network, Pennsylvania
Type 2 Diabetes
Well-child Visit Video Project
The purpose of this study is to determine if incorporating videos on the importance of minimizing infant sugar-containing beverage (SCB) consumption into well-child visit protocols increases parents' SCB-related knowledge and…
- Trial name
- NCT05011292
- Testing
- Educational Video about SCB, Survey on child feeding and related knowledge and practices, Educational Video other than SCB
- Where
- United States
- Volunteers
- 388 people
- Sponsor
- Emory University
Low-GI Dietary Education, ADA Dietary Education
Diabetic Educational Eating Plan
By improving glycemic control, many of the devastating complications of diabetes are to a large extent preventable. The use of a low GI (glycemic index) diet to improve glycemic control is relatively new and untested.
- Trial name
- DEEP (NCT00473811)
- Testing
- Low GI, ADA diet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Massachusetts, Worcester
Type 2 Diabetes Mellitus
To Evaluate the Efficacy and Safety of JT-003 add-on in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin
A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase III Study to Evaluate the Efficacy and Safety of JT-003 Add-on in Patients with Type 2 Diabetes Mellitus Inadequately Controlled with Metformin and Dapagliflozin
- Trial name
- NCT05296044
- Testing
- JT-003
- Where
- South Korea
- Volunteers
- 245 people
- Sponsor
- Jeil Pharmaceutical Co., Ltd.
Diabetes
The Glycaemic Response of Local Foods Using the Continuous Glucose Monitoring System
This study is carried out to determine the effect of high and low GI of local foods using Continuous Glucose Monitoring System (CGMS™) on 24 hour blood glucose profiles.
- Trial name
- NCT03703544
- Testing
- High glycemic index, Low glycemic index
- Where
- Singapore
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Diabetes, Erectile Dysfunction
The Prevalence of Erectile Dysfunction (ED) and ED Related Quality of Life of Diabetic Men
Adult diabetic patients aged above 20 attending the diabetic clinic of National Taiwan University Hospital are invited to attend a face to face screening and interview.
- Trial name
- NCT00173134
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Metabolic Syndrome, Insulin Resistance
Asprosin and miRNA Expression in Young Women With Metabolic Syndrome
Metabolic syndrome is a major risk factor for cardiovascular disease and type 2 diabetes, and its prevalence in young adults is increasing. Early identification of individuals at risk may improve prevention strategies.
- Conditions
- Metabolic Syndrome, Insulin Resistance, Obesity, Abdominal, Dyslipidemias
- Trial name
- ASPRO-MetS (NCT07917364)
- Testing
- Biomarker panel (asprosin, microRNA, BDNF, cortisol), Clinical and questionnaire assessment
- Where
- Poland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences in Nowy Targ
Type 1 Diabetes
Bromocriptine Quick Release (BCQR) as Adjunct Therapy in Type 1 Diabetes
Type 1 diabetes (T1D) continues to be a disease plagued by hyperglycemia, insulin resistance (IR), and increased cardiovascular disease (CVD) despite advances in insulin delivery and glucose monitoring.
- Trial name
- NCT02544321
- Testing
- Bromocriptine
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Colorado, Denver
Type 2 Diabetes
The Evaluation of Laser Lancing Devices in Adult Type 2 Diabetes Patients
Self monitoring of blood glucose level is crucial in diabetes management, but currently available methods, lancet, have shown low compliance of self monitoring of blood glucose because of pain, keratinization of finger tip…
- Trial name
- NCT05251506
- Testing
- laser lancing device or lancet for blood glucose level measurement
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Korea University Guro Hospital
Congenital Hyperinsulinism
18FluoroLDOPA PET Imaging for the Detection and Localization of Focal Congenital Hyperinsulinism
The goal of this project is to determine the role of FDOPA/PET as a pre-operative diagnostic imaging procedure for differentiating focal and diffuse forms of congenital hyperinsulinism and locating focal lesions in the pancreas…
- Trial name
- DOPA PET (NCT04205604)
- Testing
- 18F-Fluoro Dopa Imaging
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Miguel Pampaloni
Type 2 Diabetes, Patient Engagement
The Effect of The Personalized Patient Engagement Plan on Diabetes Management
This study evaluates the effect of Personalized Patient Engagement Plan on diabetes management in patients with at least six months of Type-2 Diabetes.
- Conditions
- Type 2 Diabetes, Patient Engagement, Self Efficacy, Adherence, Patient
- Trial name
- NCT04256304
- Testing
- PHEinAction-Personalized Patient Engagement Plan
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Hacettepe University
Type 2 Diabetes Mellitus
Study on Liver Fat Content and Visceral Fat Mass in Overweight and Obese Type 2 Diabetes Patients After Treatment With Basal Insulin
Primary objective: To compare the change in liver fat content and visceral fat mass (cm2) assessed by MRS (Magnetic Resonance Spectroscopy) and MRI (Magnetic Resonance Image), after 26 weeks of treatment with insulin detemir once…
- Trial name
- NCT01310452
- Testing
- insulin detemir, neutral protamine insulin
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Fudan University
Diabetes Mellitus Type 2
A Study in Type 2 Diabetes Patients Who Are Taking Moderate Dose Insulin, Looking at the Effects of the Medication Luseogliflozin on Risk of Ketoacidosis and Insulin Resistance.
The goal of this clinical trial is to learn if the drug Luseogliflozin works to treat people with diabetes who are taking moderate dose insulin treatment. It will also learn about the safety of the drug Luseogliflozin.
- Trial name
- LUSIRES (NCT07876258)
- Testing
- Luseogliflozin
- Where
- Malaysia
- Volunteers
- 40 people
- Sponsor
- Aimi Fadilah Mohamad
Health Behavior
Effects of Individual, Dyadic, and Collaborative Plans on Physical Activity in Patient-Partner Dyads
THE AIMS: The project aims at investigating of the effects of three types of planning (individual planning, collaborative planning, and dyadic planning) on physical activity.The influence of three planning interventions are…
- Trial name
- NCT02712255
- Testing
- Individual Planning, Dyadic Planning, Collaborative Planning
- Where
- Poland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Diabetes Mellitus, Type 1, Child
The Effect of Mobile Application on the Pediatric Diabetes Management
Type 1 DM; It is a chronic metabolic disease that develops as a result of the destruction of pancreatic ß cells, which are responsible for insulin production.
- Conditions
- Diabetes Mellitus, Type 1, Child, Adolescent
- Trial name
- DM (NCT05333185)
- Testing
- DİABOT (mobile application robot )
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Dokuz Eylul University
Spinal Muscular Atrophy, Merosin Deficient Congenital Muscular Dystrophy
Fat and Glucose Metabolism in Fed and Fasted State in Patients With Low Skeletal Muscle Mass
In a study from 2003 the investigators showed that adult patients with very low skeletal muscle mass (spinal muscular atrophy (SMA) type II, Duchenne muscular dystrophy, congenital muscular dystrophy) are prone to develop…
- Trial name
- NCT03970135
- Testing
- Fasting
- Where
- Denmark
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Prostatic Cancer
Metabolic Changes in Prostate Cancer Patients With Androgen-ablation Therapy (AAT)
This is an observational, prospective, non-interventional and multi-centre study, to assess the impact of androgen ablation therapy in blood triglycerides, cholesterol and glucose, body fat distribution and fracture risk to ten…
- Trial name
- UROCOR (NCT01284608)
- Where
- 33 sites in Spain
- Volunteers
- 197 people
- Sponsor
- AstraZeneca
Type 1 Diabetes
Pancreatic Islet Transplantation Into the Gastric Submucosa
The overall objective of this pilot project is to evaluate the safety and efficacy of the gastric submucosal space as a novel site for clinical islet transplantation.
- Trial name
- NCT01571817
- Testing
- Isolated Human Pancreatic Islets
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Andrew Posselt
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