Clinical trials: Glucose Metabolism
Insulin Resistance
Insulin Resistance in Adolescents
The growing population of adolescents with insulin resistance (IR) is predicted to create a large public health burden in the next few decades.
- Trial name
- NCT04089332
- Testing
- Oral Glucose Tolerance Test (OGTT), 3 Tesla MRI, Intravenous Catheter
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Diabetes Mellitus, Type 2, Hypertension
Motivational Interviewing (MI) Intervention to Improve Adherence
The purpose of this study is to examine the effectiveness of a telephone motivational interviewing intervention by pharmacy students in enhancing adherence to angiotensin converting enzyme inhibitors (ACEI)/ angiotensin receptor…
- Trial name
- MI (NCT03985098)
- Testing
- Motivational interviewing intervention arm
- Where
- United States
- Volunteers
- 727 people
- Sponsor
- University of Houston
Healthy
Molecular and Hormonal Responses to Diet-Induced Insulin Resistance
This study determined the effect of 7 days of high-fat overfeeding on whole-body glycaemic control, glucose kinetics, skeletal muscle insulin signalling, and markers of skeletal muscle microvascular function in 15 healthy young…
- Trial name
- NCT03879187
- Testing
- High-fat, high-energy diet
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Diabetes, Depression
e-Pharmacovigilance II - Surveillance for Safety and Effectiveness - Calling for Earlier Detection of Adverse Reactions
Specific Aim 1: To develop a patient-reported, EHR-integrated system to actively monitor the safety and effectiveness of treatment for patients taking FDA-approved medications for one of four common chronic conditions (diabetes…
- Conditions
- Diabetes, Depression, Insomnia, Hypertension
- Trial name
- CEDAR (NCT02087293)
- Testing
- Intervention arm - automated call and phone-based pharmacist counseling
- Where
- United States
- Volunteers
- 38,400 people
- Sponsor
- Brigham and Women's Hospital
Type 2 Diabetes Mellitus
To Assess Safety of Fixed Dose Combination of Dapagliflozin and Saxagliptin in Type 2 Diabetes Mellitus Patients
A prospective, multicenter, phase -IV study to assess the safety of fixed dose combination of dapagliflozin and saxagliptin in Indian Type 2 Diabetes Mellitus (T2D) patients.
- Trial name
- NCT04445714
- Testing
- dapagliflozin and saxagliptin
- Where
- 9 sites in India
- Volunteers
- 196 people
- Sponsor
- AstraZeneca
Type2 Diabetes, Insulin Resistance
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes
Type 2 diabetes are characterized by insulin resistance in skeletal muscle. Insulin resistance plays a major role for the increased risk of heart disease seen in type 2 diabetes.
- Trial name
- NCT03500016
- Testing
- High intensity interval training
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Diabetes Type 2
The Acute Effects of Low-dose TNF-α on Glucose Metabolism and β-cell Function in Humans
Type 2 diabetes is characterized by increased insulin resistance and impaired insulin secretion. In addition, type 2 diabetes is associated with low grade inflammation indicated by increased levels of proinflammatory cytokines…
- Trial name
- NCT01953393
- Testing
- Low-dose TNF-alpha
- Where
- Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Diabetes, Hyperlipidemia
Diabetic Under 70 (Diabetics Below 70)
A screening project of diabetics with a very high cardiovascular risk (e.g. diabetes plus coronary heart disease) who already receive cholesterol-lowering therapy.
- Conditions
- Diabetes, Hyperlipidemia, Atherosclerosis
- Trial name
- NCT00516204
- Where
- Austria
- Volunteers
- 685 people
- Sponsor
- AstraZeneca
Type 2 Diabetes
Effect of Gynostemma Pentaphyllum Tea in Insulin Sensitivity in Type 2 Diabetic Patients
The aim of the present study was to investigate the effects of Gynostemma Pentaphyllum tea on insulin sensitivity in drug-naïve type 2 diabetic patients.
- Trial name
- NCT01254084
- Testing
- Gynostemma Pentaphyllum tea
- Where
- 2 sites in Vietnam
- Volunteers
- 16 people
- Sponsor
- Hanoi Medical University
Diabetes Mellitus, Type 2
Diabetes Self Management Education Programme in Thailand
Type 2 diabetes is amongst the foremost challenges facing policy makers in Thailand, accounting for considerable death, disability and healthcare expenditure.
- Trial name
- DSMET (NCT03938233)
- Testing
- A low-cost DSME program and scalable delivery model for roll-out within the Thai primary care system
- Volunteers
- 693 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Type 2 Diabetes
Health Benefits of Aerobic and Resistance Training in Individuals With Type 2 Diabetes
The goal of the proposed study, Health Benefits of Aerobic and Resistance Training in individuals with type 2 diabetes (HART-D), is to compare the effect of resistance training alone (RT), resistance in combination with aerobic…
- Trial name
- HART-D (NCT00458133)
- Testing
- exercise
- Where
- United States
- Volunteers
- 262 people
- Sponsor
- Pennington Biomedical Research Center
Diabetes Mellitus, Type 2
A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Germany, as Part of Local Clinical Practice (SURE GERMANY)
The purpose of the study is to collect information on how semaglutide works in real world patients. Participants will get semaglutide prescribed by their study doctor. The study will last for about 6 to 8 months.
- Trial name
- SURE GERMANY (NCT04261933)
- Testing
- semaglutide
- Where
- 95 sites in Germany
- Volunteers
- 789 people
- Sponsor
- Novo Nordisk A/S
M-health, Metabolic Syndrome
Exercise-Targeted Smart Lifestyle Management
To investigate the effects of simple dietary management and diet combined with exercise capacity-targeted intelligent lifestyle management on improving metabolic indicators in patients with overweight/obesity and metabolic…
- Conditions
- M-health, Metabolic Syndrome, Lifestyle Alteration, Lifestyle (Sedentary Behavior and Physical Activity)
- Trial name
- NCT07535333
- Testing
- Dietary Prescription, Personalized Exercise Prescription, Metabolic Syndrome Prevention and Education
- Volunteers
- 435 people
- Sponsor
- China National Center for Cardiovascular Diseases
Diabetes Mellitus, Type 2
Feasibility Testing an Exercise Program to Improve Cognition for T2DM Patients
This proposed study will advance science by providing evidence on the feasibility of a standardized, rigorously designed and delivered exercise program to improve cognition and plasma brain-derived neurotrophic factor (BDNF)…
- Trial name
- NCT04590833
- Testing
- Supervised walking on a treadmill, Supervised stretching exercise
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Florida State University
Pancreatitis, Acute, Hyperglycaemia
Glucose Levels in Acute Pancreatitis and the Impact of Insulin Depletion and Bacterial Endotoxaemia
There are currently no early predictive biomarkers for severity of acute pancreatitis (AP) that would allow stratification of patients for potential early interventional therapies.
- Trial name
- GLIDE (NCT06972238)
- Volunteers
- 30 people
- Sponsor
- Manchester University NHS Foundation Trust
Type 1 Diabetes
Comparison of Exposure and Activity of SAR341402 Mix 70/30 to NovoLog Mix 70/30, NovoMix 30 and SAR341402 Rapid-acting Solution in Patients With Type 1 Diabetes Mellitus
Primary Objectives: To demonstrate similarity in exposure of SAR341402 Mix 70/30 to NovoLog Mix 70/30 and NovoMix 30 (cohort 1).
- Trial name
- NCT03916601
- Testing
- SAR341402, Insulin Aspart
- Where
- Germany
- Volunteers
- 52 people
- Sponsor
- Sanofi
Obesity, Type 2 Diabetes Prevention
The Medical College of Georgia PLAY Project: Exercise Dose and Insulin Sensitivity in Obese Children
The study is a behavioral clinical trial of aerobic exercise to determine dose-response effects on risk for type 2 diabetes, fatness, fitness, blood cholesterol levels, and other cardiovascular risk factors in overweight…
- Conditions
- Obesity, Type 2 Diabetes Prevention, Executive Function (Cognition)
- Trial name
- NCT00108901
- Testing
- Aerobic exercise program
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Metabolic Syndrome
Postprandial Glucose, Insulin Responses and Appetite Hormones to Dried Mushrooms
Obesity, characterized by an increase in body weight that results in excessive fat accumulation, is a global health problem. Recently, it has also been shown that obesity is associated with low-grade chronic systemic inflammation…
- Trial name
- NCT04444219
- Testing
- Breakfast meals
- Where
- Greece
- Volunteers
- 19 people
- Sponsor
- Harokopio University
Diabetes Mellitus, Type 2
The Effect of Reiki in Patients With Type-II Diabetes
Aim: To evaluate the effects of Reiki on subjective well-being, happiness, and some metabolic variables in patients with Type-II diabetes.
- Trial name
- NCT06617767
- Testing
- Reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Osmaniye Korkut Ata University
Type 1 Diabetes Mellitus
Mindfulness for Adolescents With Type 1 Diabetes
Adolescents with Type 1 Diabetes will be invited to the Mindfulness study. They will be randomly assigned to a Control or Active Group.
- Trial name
- NCT03942471
- Testing
- Mindfulness Based Stress Reduction
- Volunteers
- 65 people
- Sponsor
- Duquesne University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.